SE379920B - - Google Patents
Info
- Publication number
- SE379920B SE379920B SE7101222A SE122271A SE379920B SE 379920 B SE379920 B SE 379920B SE 7101222 A SE7101222 A SE 7101222A SE 122271 A SE122271 A SE 122271A SE 379920 B SE379920 B SE 379920B
- Authority
- SE
- Sweden
- Prior art keywords
- tissue
- followed
- tissue products
- products
- tissue part
- Prior art date
Links
- 210000001519 tissue Anatomy 0.000 abstract 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 230000001954 sterilising effect Effects 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 abstract 1
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 1
- 229910052782 aluminium Inorganic materials 0.000 abstract 1
- 239000004411 aluminium Substances 0.000 abstract 1
- 238000007710 freezing Methods 0.000 abstract 1
- 230000001678 irradiating effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000000944 nerve tissue Anatomy 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000004321 preservation Methods 0.000 abstract 1
- 238000007789 sealing Methods 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 238000004659 sterilization and disinfection Methods 0.000 abstract 1
- 238000001356 surgical procedure Methods 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/124—Disinfecting agents, e.g. antimicrobials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0029—Radiation
- A61L2/0035—Gamma radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
- A61L2/0094—Gaseous substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Botany (AREA)
- Zoology (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Materials For Medical Uses (AREA)
Abstract
1,274,409. Tissue products. B. BRAUN. 19 April, 1971 [2 Feb., 1970], No. 20725/71. Heading A2D. A process for the production of human or animal tissue products for use in surgery comprises introducing a tissue part into a concentrated sodium chloride solution for preservation and removal of enzymes, washing in water or treating with a dilute hydrogen peroxide solution, followed by slow deep-freezing and subsequently lyophilizing and sterilizing. The tissue part is preferably nerve tissue. The sterilization may be carried out under vacuum with ethylene oxide or alternatively the dry lyophilized preparation may be placed in a bag of polyethylene-aluminium laminate, followed by sealing, and irradiating with gamma rays.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2004553 | 1970-02-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
SE379920B true SE379920B (en) | 1975-10-27 |
Family
ID=5761154
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7101222A SE379920B (en) | 1970-02-02 | 1971-02-01 |
Country Status (13)
Country | Link |
---|---|
AT (1) | AT298664B (en) |
BR (1) | BR7100718D0 (en) |
CH (1) | CH557167A (en) |
DE (1) | DE2004553B1 (en) |
DK (1) | DK127663B (en) |
ES (1) | ES387801A1 (en) |
FI (1) | FI54217C (en) |
FR (1) | FR2112171B1 (en) |
GB (1) | GB1274409A (en) |
IT (1) | IT983092B (en) |
NL (1) | NL148801B (en) |
NO (1) | NO129120B (en) |
SE (1) | SE379920B (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2944278C2 (en) * | 1979-11-02 | 1983-07-21 | Karl Eugen Prof. Dr.med. 7302 Ostfildern Theurer | Process for the gentle sterilization of biological active substances, in particular of organ tissue for therapeutic purposes against microorganisms and viruses |
ATE13477T1 (en) * | 1981-07-02 | 1985-06-15 | Intermedicat Gmbh | PROCESS FOR THE PRODUCTION OF SCLEROPROTEIN TRANSPLANTS WITH INCREASED BIOLOGICAL STABILITY. |
GB2150811B (en) * | 1983-12-06 | 1987-04-08 | Ethicon Inc | Surgical training aid |
GB8807187D0 (en) * | 1988-03-25 | 1988-04-27 | Harrison J F | Improvements in/relating to inactivation of infectious agents |
EP0424159A3 (en) * | 1989-10-19 | 1991-11-06 | Osteotech, Inc., | Aseptic processing of allograft bone and tissue |
DE10217779A1 (en) | 2002-04-18 | 2003-11-13 | Co Don Ag | Preserved tissue matrix of a hollow organ, especially a blood vessel, process for the production and use thereof |
MX349920B (en) * | 2012-05-09 | 2017-08-21 | Icrom Spa | Production of sterile active pharmaceutical ingredients. |
-
1970
- 1970-02-02 DE DE19702004553D patent/DE2004553B1/en active Pending
-
1971
- 1971-01-14 AT AT25971A patent/AT298664B/en not_active IP Right Cessation
- 1971-01-26 FI FI207/71A patent/FI54217C/en active
- 1971-01-28 CH CH125171A patent/CH557167A/en not_active IP Right Cessation
- 1971-01-28 NL NL717101140A patent/NL148801B/en not_active IP Right Cessation
- 1971-01-29 DK DK41971AA patent/DK127663B/en unknown
- 1971-01-29 BR BR718/71A patent/BR7100718D0/en unknown
- 1971-01-30 IT IT19988/71A patent/IT983092B/en active
- 1971-01-30 ES ES387801A patent/ES387801A1/en not_active Expired
- 1971-02-01 NO NO00347/71*[A patent/NO129120B/no unknown
- 1971-02-01 FR FR7103224A patent/FR2112171B1/fr not_active Expired
- 1971-02-01 SE SE7101222A patent/SE379920B/xx unknown
- 1971-04-19 GB GB20725/71A patent/GB1274409A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
BR7100718D0 (en) | 1973-04-19 |
FR2112171A1 (en) | 1972-06-16 |
CH557167A (en) | 1974-12-31 |
NL7101140A (en) | 1971-08-04 |
NO129120B (en) | 1974-03-04 |
FR2112171B1 (en) | 1974-04-12 |
NL148801B (en) | 1976-03-15 |
FI54217B (en) | 1978-07-31 |
GB1274409A (en) | 1972-05-17 |
AT298664B (en) | 1972-05-25 |
ES387801A1 (en) | 1974-01-16 |
IT983092B (en) | 1974-10-31 |
FI54217C (en) | 1978-11-10 |
DE2004553B1 (en) | 1971-05-19 |
DK127663B (en) | 1973-12-17 |
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