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SA518391159B1 - مترافقات الألفة- قليلة النيوكليوتيد واستخداماتها - Google Patents

مترافقات الألفة- قليلة النيوكليوتيد واستخداماتها

Info

Publication number
SA518391159B1
SA518391159B1 SA518391159A SA518391159A SA518391159B1 SA 518391159 B1 SA518391159 B1 SA 518391159B1 SA 518391159 A SA518391159 A SA 518391159A SA 518391159 A SA518391159 A SA 518391159A SA 518391159 B1 SA518391159 B1 SA 518391159B1
Authority
SA
Saudi Arabia
Prior art keywords
affinity
oligonucleotide conjugates
conjugates
oligonucleotide
composition
Prior art date
Application number
SA518391159A
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English (en)
Inventor
ورانجهام بريجـز ادريان
جيه بلمونت براين
جيه جولدفليس ستيفن
فيجنياولت فرانسوا
Original Assignee
ابفيترو ال ال سي
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ابفيترو ال ال سي filed Critical ابفيترو ال ال سي
Publication of SA518391159B1 publication Critical patent/SA518391159B1/ar

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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/6869—Methods for sequencing
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    • C12N15/09—Recombinant DNA-technology
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    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
    • C—CHEMISTRY; METALLURGY
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
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    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/159—Microreactors, e.g. emulsion PCR or sequencing, droplet PCR, microcapsules, i.e. non-liquid containers with a range of different permeability's for different reaction components
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    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/179—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a nucleic acid
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    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/185—Nucleic acid dedicated to use as a hidden marker/bar code, e.g. inclusion of nucleic acids to mark art objects or animals
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
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    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/7051—T-cell receptor (TcR)-CD3 complex
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    • G01N2333/70514—CD4
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    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70539—MHC-molecules, e.g. HLA-molecules
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/10—Oligonucleotides as tagging agents for labelling antibodies

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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Abstract

يتعلق الاختراع الحالي بتوفير طرق وتركيبات لتمييز الخلايا الفردية باستخدام مترافقات الألفة- قليلة النيوكليوتيد. شكل 9أ.
SA518391159A 2015-09-24 2018-03-21 مترافقات الألفة- قليلة النيوكليوتيد واستخداماتها SA518391159B1 (ar)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562232209P 2015-09-24 2015-09-24
PCT/US2016/053598 WO2017053905A1 (en) 2015-09-24 2016-09-24 Affinity-oligonucleotide conjugates and uses thereof

Publications (1)

Publication Number Publication Date
SA518391159B1 true SA518391159B1 (ar) 2022-02-22

Family

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Country Status (17)

Country Link
US (4) US11156611B2 (ar)
EP (3) EP3353326B1 (ar)
JP (2) JP6869233B2 (ar)
KR (2) KR20180085717A (ar)
CN (2) CN108291257B (ar)
AU (1) AU2016326737B2 (ar)
BR (1) BR112018005937A2 (ar)
CA (2) CA2999888C (ar)
ES (1) ES2928681T3 (ar)
IL (1) IL258248B (ar)
MX (3) MX2018003532A (ar)
MY (2) MY193806A (ar)
PH (2) PH12018500647A1 (ar)
RU (1) RU2763554C2 (ar)
SA (1) SA518391159B1 (ar)
SG (1) SG10201912906RA (ar)
WO (1) WO2017053905A1 (ar)

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