RU98102774A - Транскорнеальная система высвобождения лекарства - Google Patents
Транскорнеальная система высвобождения лекарстваInfo
- Publication number
- RU98102774A RU98102774A RU98102774/14A RU98102774A RU98102774A RU 98102774 A RU98102774 A RU 98102774A RU 98102774/14 A RU98102774/14 A RU 98102774/14A RU 98102774 A RU98102774 A RU 98102774A RU 98102774 A RU98102774 A RU 98102774A
- Authority
- RU
- Russia
- Prior art keywords
- active substance
- paragraphs
- microneedles
- microneedle
- transkornalnaya
- Prior art date
Links
- 239000003814 drug Substances 0.000 title claims 5
- 229940079593 drug Drugs 0.000 title claims 5
- 239000013543 active substance Substances 0.000 claims 7
- 238000013270 controlled release Methods 0.000 claims 3
- 230000001276 controlling effect Effects 0.000 claims 1
- 230000005611 electricity Effects 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
- 230000009885 systemic effect Effects 0.000 claims 1
- 229920001169 thermoplastic Polymers 0.000 claims 1
Claims (15)
1. Транскорнеальная система для контролируемого высвобождения лекарств, содержащая резервуар для приема активного вещества и снабженное микроиглами или микролезвиями устройство для аппликации активного вещества.
2. Транскорнеальная система по п. 1, отличающаяся тем, что микроиглы соответственно микролезвия выполнены с длиной (глубиной), по меньшей мере соответствующей толщине корнеальных слоев кожи.
3. Транскорнеальная система для контролируемого высвобождения лекарств, содержащая резервуар для приема активного вещества и устройство, снабженное микроиглами, через которые апплицируется активное вещество в виде раствора.
4. Транскорнеальная система по пп. 1, 2 или 3, отличающаяся тем, что ее обращенная к коже сторона снабжена множеством микроигл.
5. Транскорнеальная система по одному из предыдущих пунктов, отличающаяся тем, что она включает устройство, обеспечивающее возможность подачи активного вещества из резервуара через отверстия микроигл в кожу.
6. Транскорнеальная система по одному из предыдущих пунктов, отличающаяся тем, что она содержит устройство для снабжения электроэнергией.
7. Транскорнеальная система по одному из предыдущих пунктов, отличающаяся тем, что она содержит устройства для контроля и регулирования высвобождения активного вещества.
8. Транскорнеальная система по одному из предыдущих пунктов, отличающаяся тем, что, по меньшей мере, одна из стенок резервуара выполнена или установлена подвижно.
9. Микроигла для аппликации лекарств в виде растворов, отличающаяся тем, что она имеет длину, по меньшей мере, 10 мкм.
10. Микроигла по п. 9, отличающаяся тем, что она снабжена, по меньшей мере, одним отверстием в виде круглого(ых) окна(окон) и/или щели(ей).
11. Микроигла по п. 9 или 10, отличающаяся тем, что она представляет собой составную часть резервуара для приема активного вещества.
12. Микроигла по одному из пп. 9-11, отличающаяся тем, что она выполнена из термопластичной пластмассы.
13. Микроигла по одному из пп. 9-12, отличающаяся тем, что ее кончик имеет радиус кривизны менее 10 мкм.
14. Микроигла по одному из пп. 9-13, отличающаяся тем, что она выполнена из пористого-проницаемого для жидкостей-материала.
15. Применение транскорнеальной системы согласно пп. 1-8 для контролируемого высвобождения лекарств с системным действием.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19525607A DE19525607A1 (de) | 1995-07-14 | 1995-07-14 | Transcorneales Arzneimittelfreigabesystem |
| DE19525607.7 | 1995-07-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU98102774A true RU98102774A (ru) | 2000-01-27 |
| RU2209640C2 RU2209640C2 (ru) | 2003-08-10 |
Family
ID=7766771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU98102774/14A RU2209640C2 (ru) | 1995-07-14 | 1996-07-15 | Транскорнеальная система высвобождения лекарства |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US6132755A (ru) |
| EP (1) | EP0840634B1 (ru) |
| JP (1) | JPH11509123A (ru) |
| KR (1) | KR100430703B1 (ru) |
| CN (1) | CN1183979C (ru) |
| AR (1) | AR004499A1 (ru) |
| AT (1) | ATE207769T1 (ru) |
| AU (1) | AU722943B2 (ru) |
| BG (1) | BG63142B1 (ru) |
| BR (1) | BR9609796A (ru) |
| CA (1) | CA2226718C (ru) |
| CO (1) | CO4700491A1 (ru) |
| CZ (1) | CZ290458B6 (ru) |
| DE (2) | DE19525607A1 (ru) |
| DK (1) | DK0840634T3 (ru) |
| EE (1) | EE04006B1 (ru) |
| ES (1) | ES2163035T3 (ru) |
| HK (1) | HK1010844A1 (ru) |
| HU (1) | HU222342B1 (ru) |
| IL (1) | IL122907A0 (ru) |
| MX (1) | MX9800401A (ru) |
| NO (1) | NO316313B1 (ru) |
| NZ (1) | NZ313984A (ru) |
| PL (1) | PL181658B1 (ru) |
| PT (1) | PT840634E (ru) |
| RO (1) | RO118738B1 (ru) |
| RU (1) | RU2209640C2 (ru) |
| SK (1) | SK284358B6 (ru) |
| TR (1) | TR199800048T1 (ru) |
| TW (1) | TW375528B (ru) |
| UA (1) | UA62918C2 (ru) |
| UY (1) | UY24277A1 (ru) |
| WO (1) | WO1997003718A1 (ru) |
| ZA (1) | ZA965931B (ru) |
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| US3964482A (en) * | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
| US4622031A (en) * | 1983-08-18 | 1986-11-11 | Drug Delivery Systems Inc. | Indicator for electrophoretic transcutaneous drug delivery device |
| GB2221394B (en) * | 1988-08-05 | 1992-03-04 | Eilert Eilertsen | An injection device |
| CA2149836C (en) * | 1994-05-23 | 1999-07-06 | Sang Bae Choi | Perforating device for dermal administration |
-
1995
- 1995-07-14 DE DE19525607A patent/DE19525607A1/de not_active Withdrawn
-
1996
- 1996-07-10 TW TW085108368A patent/TW375528B/zh not_active IP Right Cessation
- 1996-07-11 UY UY24277A patent/UY24277A1/es not_active IP Right Cessation
- 1996-07-12 CO CO96036735A patent/CO4700491A1/es unknown
- 1996-07-12 ZA ZA9605931A patent/ZA965931B/xx unknown
- 1996-07-12 AR ARP960103564A patent/AR004499A1/es unknown
- 1996-07-15 NZ NZ313984A patent/NZ313984A/xx not_active IP Right Cessation
- 1996-07-15 RU RU98102774/14A patent/RU2209640C2/ru not_active IP Right Cessation
- 1996-07-15 CZ CZ1998118A patent/CZ290458B6/cs not_active IP Right Cessation
- 1996-07-15 EP EP96926348A patent/EP0840634B1/de not_active Expired - Lifetime
- 1996-07-15 UA UA98020771A patent/UA62918C2/uk unknown
- 1996-07-15 SK SK49-98A patent/SK284358B6/sk not_active IP Right Cessation
- 1996-07-15 PT PT96926348T patent/PT840634E/pt unknown
- 1996-07-15 BR BR9609796A patent/BR9609796A/pt not_active IP Right Cessation
- 1996-07-15 MX MX9800401A patent/MX9800401A/es unknown
- 1996-07-15 EE EE9800025A patent/EE04006B1/xx unknown
- 1996-07-15 PL PL96324530A patent/PL181658B1/pl unknown
- 1996-07-15 RO RO98-00032A patent/RO118738B1/ro unknown
- 1996-07-15 ES ES96926348T patent/ES2163035T3/es not_active Expired - Lifetime
- 1996-07-15 WO PCT/EP1996/003090 patent/WO1997003718A1/de active IP Right Grant
- 1996-07-15 CA CA002226718A patent/CA2226718C/en not_active Expired - Fee Related
- 1996-07-15 DE DE59608081T patent/DE59608081D1/de not_active Expired - Lifetime
- 1996-07-15 AU AU66567/96A patent/AU722943B2/en not_active Ceased
- 1996-07-15 AT AT96926348T patent/ATE207769T1/de active
- 1996-07-15 CN CNB96195485XA patent/CN1183979C/zh not_active Expired - Fee Related
- 1996-07-15 IL IL12290796A patent/IL122907A0/xx not_active IP Right Cessation
- 1996-07-15 KR KR10-1998-0700268A patent/KR100430703B1/ko not_active IP Right Cessation
- 1996-07-15 DK DK96926348T patent/DK0840634T3/da active
- 1996-07-15 TR TR1998/00048T patent/TR199800048T1/xx unknown
- 1996-07-15 US US08/983,197 patent/US6132755A/en not_active Expired - Lifetime
- 1996-07-15 HU HU9802773A patent/HU222342B1/hu not_active IP Right Cessation
- 1996-07-15 JP JP9506273A patent/JPH11509123A/ja active Pending
-
1998
- 1998-01-13 NO NO19980147A patent/NO316313B1/no not_active IP Right Cessation
- 1998-01-20 BG BG102200A patent/BG63142B1/bg unknown
- 1998-11-09 HK HK98111847A patent/HK1010844A1/xx not_active IP Right Cessation
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