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MX9800401A - Sistema transcorneal de liberacion de medicamentos. - Google Patents

Sistema transcorneal de liberacion de medicamentos.

Info

Publication number
MX9800401A
MX9800401A MX9800401A MX9800401A MX9800401A MX 9800401 A MX9800401 A MX 9800401A MX 9800401 A MX9800401 A MX 9800401A MX 9800401 A MX9800401 A MX 9800401A MX 9800401 A MX9800401 A MX 9800401A
Authority
MX
Mexico
Prior art keywords
release system
transcorneal
drug
transcorneal drug
novel
Prior art date
Application number
MX9800401A
Other languages
English (en)
Other versions
MXPA98000401A (es
Inventor
Joachim Eicher
Bernd Zierenberg
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of MXPA98000401A publication Critical patent/MXPA98000401A/es
Publication of MX9800401A publication Critical patent/MX9800401A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

El presente invento concierne a un nuevo sistema transcorneal de liberacion de medicamentos.
MX9800401A 1995-07-14 1996-07-15 Sistema transcorneal de liberacion de medicamentos. MX9800401A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19525607A DE19525607A1 (de) 1995-07-14 1995-07-14 Transcorneales Arzneimittelfreigabesystem
DE19525607.7 1995-07-14
PCT/EP1996/003090 WO1997003718A1 (de) 1995-07-14 1996-07-15 Transcorneales arzneimittelfreigabesystem

Publications (2)

Publication Number Publication Date
MXPA98000401A MXPA98000401A (es) 1998-04-01
MX9800401A true MX9800401A (es) 1998-04-30

Family

ID=7766771

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9800401A MX9800401A (es) 1995-07-14 1996-07-15 Sistema transcorneal de liberacion de medicamentos.

Country Status (34)

Country Link
US (1) US6132755A (es)
EP (1) EP0840634B1 (es)
JP (1) JPH11509123A (es)
KR (1) KR100430703B1 (es)
CN (1) CN1183979C (es)
AR (1) AR004499A1 (es)
AT (1) ATE207769T1 (es)
AU (1) AU722943B2 (es)
BG (1) BG63142B1 (es)
BR (1) BR9609796A (es)
CA (1) CA2226718C (es)
CO (1) CO4700491A1 (es)
CZ (1) CZ290458B6 (es)
DE (2) DE19525607A1 (es)
DK (1) DK0840634T3 (es)
EE (1) EE04006B1 (es)
ES (1) ES2163035T3 (es)
HK (1) HK1010844A1 (es)
HU (1) HU222342B1 (es)
IL (1) IL122907A0 (es)
MX (1) MX9800401A (es)
NO (1) NO316313B1 (es)
NZ (1) NZ313984A (es)
PL (1) PL181658B1 (es)
PT (1) PT840634E (es)
RO (1) RO118738B1 (es)
RU (1) RU2209640C2 (es)
SK (1) SK284358B6 (es)
TR (1) TR199800048T1 (es)
TW (1) TW375528B (es)
UA (1) UA62918C2 (es)
UY (1) UY24277A1 (es)
WO (1) WO1997003718A1 (es)
ZA (1) ZA965931B (es)

Families Citing this family (291)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0914178B1 (en) * 1996-06-18 2003-03-12 Alza Corporation Device for enhancing transdermal agent delivery or sampling
US6746688B1 (en) * 1996-10-13 2004-06-08 Neuroderm Ltd. Apparatus for the transdermal treatment of Parkinson's disease
EP0957972B1 (en) * 1996-12-20 2003-03-19 Alza Corporation Device and method for enhancing transdermal agent flux
JP3879785B2 (ja) * 1997-05-20 2007-02-14 日東電工株式会社 キラーt細胞賦活剤
US6918901B1 (en) 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
AU757230B2 (en) 1997-12-11 2003-02-06 Alza Corporation Device for enhancing transdermal agent flux
US6083196A (en) * 1997-12-11 2000-07-04 Alza Corporation Device for enhancing transdermal agent flux
CA2330207C (en) * 1998-06-10 2005-08-30 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US7344499B1 (en) 1998-06-10 2008-03-18 Georgia Tech Research Corporation Microneedle device for extraction and sensing of bodily fluids
GB9815820D0 (en) * 1998-07-22 1998-09-16 Secr Defence Improvements relating to micro-machining
GB9815819D0 (en) * 1998-07-22 1998-09-16 Secr Defence Transferring materials into cells and a microneedle array
US6532386B2 (en) 1998-08-31 2003-03-11 Johnson & Johnson Consumer Companies, Inc. Electrotransort device comprising blades
EP1113832A4 (en) * 1998-09-18 2002-04-17 Univ Utah Res Found MICRO-MACHINED NEEDLES ON A SURFACE
US7048723B1 (en) * 1998-09-18 2006-05-23 The University Of Utah Research Foundation Surface micromachined microneedles
AU2189400A (en) * 1998-12-18 2000-07-03 Minimed, Inc. Insertion sets with micro-piercing members for use with medical devices and methods of using the same
DE60018726T2 (de) 1999-04-16 2006-04-13 Johnson & Johnson Consumer Companies, Inc. Vorrichtung zur iontophoretischen verabreichung von medikamenten mit internen sensoren
US6611707B1 (en) 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
CA2376128C (en) * 1999-06-04 2009-01-06 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6743211B1 (en) 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6379324B1 (en) 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6312612B1 (en) 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
US6256533B1 (en) * 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6890553B1 (en) 1999-07-08 2005-05-10 Johnson & Johnson Consumer Companies, Inc. Exothermic topical delivery device
AU6076200A (en) 1999-07-08 2001-01-30 Johnson & Johnson Consumer Companies, Inc. Exothermic bandage
US7133717B2 (en) 1999-08-25 2006-11-07 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
US7113821B1 (en) 1999-08-25 2006-09-26 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery
US6623457B1 (en) * 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
US6835184B1 (en) * 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
DE60020159T2 (de) * 1999-12-10 2005-10-06 Alza Corp., Mountain View Hautbehandlungsvorrichtung zur verlängerten transdermalen verabreichung von medikamenten
WO2001041863A1 (en) 1999-12-10 2001-06-14 Alza Corporation Device and method for enhancing microprotrusion skin piercing
AU2542001A (en) * 2000-01-21 2001-07-31 Instrumentarium Corporation Medical electrode
US6622035B1 (en) 2000-01-21 2003-09-16 Instrumentarium Corp. Electrode for measurement of weak bioelectrical signals
IL134997A0 (en) * 2000-03-09 2001-05-20 Yehoshua Yeshurun Health care system based on micro device
AU2001245472A1 (en) * 2000-03-09 2001-09-17 Nanopass Ltd. Systems and methods for the transport of fluids through a biological barrier andproduction techniques for such systems
US7404815B2 (en) 2000-05-01 2008-07-29 Lifescan, Inc. Tissue ablation by shear force for sampling biological fluids and delivering active agents
US6629949B1 (en) 2000-05-08 2003-10-07 Sterling Medivations, Inc. Micro infusion drug delivery device
US6659982B2 (en) * 2000-05-08 2003-12-09 Sterling Medivations, Inc. Micro infusion drug delivery device
US6595947B1 (en) 2000-05-22 2003-07-22 Becton, Dickinson And Company Topical delivery of vaccines
US6565532B1 (en) 2000-07-12 2003-05-20 The Procter & Gamble Company Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup
US6589202B1 (en) * 2000-06-29 2003-07-08 Becton Dickinson And Company Method and apparatus for transdermally sampling or administering a substance to a patient
US6656147B1 (en) 2000-07-17 2003-12-02 Becton, Dickinson And Company Method and delivery device for the transdermal administration of a substance
GB0017999D0 (en) * 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
US6533949B1 (en) 2000-08-28 2003-03-18 Nanopass Ltd. Microneedle structure and production method therefor
BR0113749A (pt) 2000-09-08 2004-06-22 Alza Corp Métodos para inibir a diminuição no fluxo de droga transdérmica por inibição do fechamento das vias
JP2002085561A (ja) * 2000-09-14 2002-03-26 Terumo Corp 液体注入針
AU2002210881A1 (en) * 2000-10-12 2002-04-22 Ink Jet Technology Ltd. Transdermal method
EP1341453B1 (en) 2000-10-13 2009-04-15 Alza Corporation Apparatus and method for piercing skin with microprotrusions
US7419481B2 (en) 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
RU2277390C2 (ru) 2000-10-13 2006-06-10 Алза Корпорейшн Аппликатор для силового воздействия комплектом микроножей
CZ20031302A3 (cs) 2000-10-13 2003-10-15 Alza Corporation Prvek zadržující mikrovýčnělkový prvek pro nárazový aplikátor
US7131987B2 (en) * 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
US6821281B2 (en) * 2000-10-16 2004-11-23 The Procter & Gamble Company Microstructures for treating and conditioning skin
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
RU2282468C2 (ru) 2000-10-26 2006-08-27 Алза Корпорейшн Устройство для трансдермальной доставки лекарственных средств, имеющее микровыступы с покрытием
US6638246B1 (en) 2000-11-28 2003-10-28 Scimed Life Systems, Inc. Medical device for delivery of a biologically active material to a lumen
EP1345646A2 (en) 2000-12-14 2003-09-24 Georgia Tech Research Corporation Microneedle devices and production thereof
WO2002050584A2 (en) 2000-12-21 2002-06-27 Biovalve Technologies, Inc. Microneedle array systems
DE10065168A1 (de) * 2000-12-23 2002-07-11 Lohmann Therapie Syst Lts Nadelpflaster mit vermindertem Infektionsrisiko
US6663820B2 (en) 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
WO2002074173A1 (en) 2001-03-16 2002-09-26 Alza Corporation Method and apparatus for coating skin piercing microprojections
EP3251722B1 (en) 2001-04-20 2020-06-17 ALZA Corporation Microprojection array having a beneficial agent containing coating and method of forming the coating thereon
KR20040020889A (ko) 2001-04-20 2004-03-09 알자 코포레이션 유용한 약물을 갖는 코팅을 포함하는 미세돌출부 어레이
US6591124B2 (en) 2001-05-11 2003-07-08 The Procter & Gamble Company Portable interstitial fluid monitoring system
WO2002100476A2 (en) * 2001-06-08 2002-12-19 Becton, Dickinson And Company Device for manipulating a needle or abrader array
SE0102736D0 (sv) * 2001-08-14 2001-08-14 Patrick Griss Side opened out-of-plane microneedles for microfluidic transdermal interfacing and fabrication process of side opened out-of-plane microneedles
US6881203B2 (en) 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
WO2003024507A2 (en) 2001-09-19 2003-03-27 Biovalve Technologies, Inc. Microneedles, microneedle arrays, and systems and methods relating to same
AU2002330083A1 (en) * 2001-09-21 2003-04-01 Biovalve Technologies, Inc. Gas pressure actuated microneedle arrays, and systems and methods relating to same
US6830562B2 (en) 2001-09-27 2004-12-14 Unomedical A/S Injector device for placing a subcutaneous infusion set
EP1469903A2 (en) * 2001-09-28 2004-10-27 BioValve Technologies, Inc. Microneedle with membrane
CA2500452A1 (en) * 2001-09-28 2003-04-03 Biovalve Technologies, Inc. Switchable microneedle arrays and systems and methods relating to same
US6689100B2 (en) 2001-10-05 2004-02-10 Becton, Dickinson And Company Microdevice and method of delivering or withdrawing a substance through the skin of an animal
EP1439870B1 (en) * 2001-10-29 2009-01-14 Becton, Dickinson and Company Device for the delivery of a substance
US20040120964A1 (en) * 2001-10-29 2004-06-24 Mikszta John A. Needleless vaccination using chimeric yellow fever vaccine-vectored vaccines against heterologous flaviviruses
US6908453B2 (en) 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
US7858112B2 (en) 2002-02-28 2010-12-28 Lintec Corporation Percutaneous absorption system and percutaneous absorption method
JP4608187B2 (ja) * 2002-02-28 2011-01-05 リンテック株式会社 経皮吸収型製剤
AU2003209645A1 (en) * 2002-03-04 2003-09-16 Nano Pass Technologies Ltd. Devices and methods for transporting fluid across a biological barrier
JP4026745B2 (ja) * 2002-03-26 2007-12-26 財団法人大阪産業振興機構 医療用システムおよびその製造方法
EP1594559B1 (en) 2002-03-26 2013-02-13 Becton, Dickinson and Company Multi-stage fluid delivery device
US7115108B2 (en) 2002-04-02 2006-10-03 Becton, Dickinson And Company Method and device for intradermally delivering a substance
US7047070B2 (en) * 2002-04-02 2006-05-16 Becton, Dickinson And Company Valved intradermal delivery device and method of intradermally delivering a substance to a patient
US6780171B2 (en) * 2002-04-02 2004-08-24 Becton, Dickinson And Company Intradermal delivery device
US6945952B2 (en) * 2002-06-25 2005-09-20 Theraject, Inc. Solid solution perforator for drug delivery and other applications
KR101061975B1 (ko) 2002-06-25 2011-09-05 권성윤 약물 송달 및 다른 용도를 위한 신속 용해형 마이크로 퍼포레이터를 포함하는 어레이
US6899838B2 (en) * 2002-07-12 2005-05-31 Becton, Dickinson And Company Method of forming a mold and molding a micro-device
BR0312671A (pt) * 2002-07-19 2005-04-26 3M Innovative Properties Co Dispositivo de microagulhas, método para utilizar um dispositivo de microagulhas, e, método para aplicar um dispositivo de microagulhas
BRPI0312846B8 (pt) * 2002-07-22 2021-06-22 Becton Dickinson Co dispositivo de infusão semelhante a emplastro
US20040051019A1 (en) 2002-09-02 2004-03-18 Mogensen Lasse Wesseltoft Apparatus for and a method of adjusting the length of an infusion tube
WO2004024224A1 (en) * 2002-09-16 2004-03-25 Sung-Yun Kwon Solid micro-perforators and methods of use
DE10243917A1 (de) * 2002-09-20 2004-04-01 Udo Dr. Auweiler Vorrichtung zur subkutanen Abgabe eines pharmazeutischen Wirkstoffes
US20040106904A1 (en) * 2002-10-07 2004-06-03 Gonnelli Robert R. Microneedle array patch
IL152573A (en) * 2002-10-31 2009-11-18 Transpharma Medical Ltd A system for the transmission through the skin of a medical preparation against vomiting and nausea
IL152575A (en) * 2002-10-31 2008-12-29 Transpharma Medical Ltd A skin-to-skin transmission system of water-insoluble drugs
IL152912A0 (en) * 2002-11-18 2003-06-24 Nanopass Ltd Micro needle systems
DK200201823A (da) 2002-11-26 2004-05-27 Maersk Medical As Forbindelsesstykke for en slangeforbindelse
EP1426662A1 (de) * 2002-12-06 2004-06-09 Boehringer Ingelheim International GmbH Kolbenpumpsystem
US7578954B2 (en) 2003-02-24 2009-08-25 Corium International, Inc. Method for manufacturing microstructures having multiple microelements with through-holes
EP1624914B1 (en) 2003-05-08 2008-04-16 Novo Nordisk A/S Internal needle inserter
WO2004098684A2 (en) * 2003-05-08 2004-11-18 Novo Nordisk A/S Skin mountable injection device with a detachable needle insertion actuation
EP1475113A1 (en) * 2003-05-08 2004-11-10 Novo Nordisk A/S External needle inserter
JP5456234B2 (ja) 2003-06-30 2014-03-26 アルザ・コーポレーシヨン 非揮発性の対イオンを含有する被覆された微小突起のための製剤
EP1502613A1 (en) 2003-08-01 2005-02-02 Novo Nordisk A/S Needle device with retraction means
CA2534726C (en) 2003-08-12 2015-04-28 Becton, Dickinson And Company Patch-like infusion device
CA2536249A1 (en) 2003-08-25 2005-03-10 3M Innovative Properties Company Delivery of immune response modifier compounds
EP1675539A4 (en) 2003-10-24 2007-09-12 Alza Corp METHOD AND SYSTEM FOR PRETREATMENT FOR IMPROVING TRANSDERMAL DRUG DELIVERY
BRPI0415986A (pt) 2003-10-28 2007-01-23 Alza Corp método e aparelho para reduzir a incidência do uso de tabaco
US7097631B2 (en) 2003-10-31 2006-08-29 Alza Corporation Self-actuating applicator for microprojection array
US7753888B2 (en) * 2003-11-21 2010-07-13 The Regents Of The University Of California Method and/or apparatus for puncturing a surface for extraction, in situ analysis, and/or substance delivery using microneedles
US8017145B2 (en) * 2003-12-22 2011-09-13 Conopco, Inc. Exfoliating personal care wipe article containing an array of projections
JP2007516781A (ja) * 2003-12-29 2007-06-28 スリーエム イノベイティブ プロパティズ カンパニー 医療用具および該医療用具を含むキット
WO2005082593A1 (en) * 2004-02-17 2005-09-09 Avery Dennison Corporation Method of making microneedles
US20070191761A1 (en) * 2004-02-23 2007-08-16 3M Innovative Properties Company Method of molding for microneedle arrays
US7591618B2 (en) 2004-02-25 2009-09-22 Agency For Science, Technology And Research Machining method for micro abraders and micro abraders produced thereby
JP2005246595A (ja) * 2004-03-05 2005-09-15 Ritsumeikan マイクロニードルアレイ及びその製造方法
WO2005094526A2 (en) 2004-03-24 2005-10-13 Corium International, Inc. Transdermal delivery device
WO2005092410A1 (en) 2004-03-26 2005-10-06 Unomedical A/S Infusion set
EP1732626A1 (en) 2004-03-30 2006-12-20 Novo Nordisk A/S Actuator system comprising lever mechanism
CN100402107C (zh) * 2004-03-31 2008-07-16 中国科学院理化技术研究所 金属微针阵列芯片及其制备方法和用途
ES2650188T3 (es) * 2004-06-10 2018-01-17 3M Innovative Properties Company Dispositivo y kit de aplicación de parches
US8062250B2 (en) 2004-08-10 2011-11-22 Unomedical A/S Cannula device
ITPD20040252A1 (it) * 2004-10-14 2005-01-14 Bidoia Sas Di Gianfranco Bidoi Irrigatore chirurgico
US9174035B2 (en) 2004-11-18 2015-11-03 3M Innovative Properties Company Microneedle array applicator and retainer
JP5015787B2 (ja) 2004-11-18 2012-08-29 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイの接触コーティング法
CA2587505C (en) 2004-11-18 2013-01-08 3M Innovative Properties Company Low-profile microneedle array applicator
AU2005306426B2 (en) * 2004-11-18 2011-04-28 3M Innovative Properties Company Masking method for coating a microneedle array
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
US20080009800A1 (en) * 2004-12-02 2008-01-10 Nickel Janice H Transdermal drug delivery device
CN102358015A (zh) * 2004-12-07 2012-02-22 3M创新有限公司 模制微型针的方法
AU2005313662B2 (en) 2004-12-10 2011-07-14 Unomedical A/S Cannula inserter
EP1669100A1 (en) * 2004-12-13 2006-06-14 Debiotech S.A. Micro-needle
US8167841B2 (en) 2005-01-24 2012-05-01 Novo Nordisk A/S Transcutaneous device assembly
KR100679714B1 (ko) * 2005-02-07 2007-02-07 재단법인서울대학교산학협력재단 3차원 구조의 마이크로 스파이크 및 그 제조 방법
US7985199B2 (en) 2005-03-17 2011-07-26 Unomedical A/S Gateway system
JP4793806B2 (ja) * 2005-03-22 2011-10-12 Tti・エルビュー株式会社 イオントフォレーシス装置
WO2006101146A1 (ja) * 2005-03-22 2006-09-28 Transcutaneous Technologies Inc. イオントフォレーシス装置
EP1885210A1 (en) * 2005-03-23 2008-02-13 Velcro Industries B.V. Molding touch fastener elements
CA2602259A1 (en) 2005-03-29 2006-10-05 Arkal Medical, Inc. Devices, systems, methods and tools for continuous glucose monitoring
US7601284B2 (en) * 2005-04-06 2009-10-13 Velcro Industries B.V. Molding fastener elements on folded substrate
US10035008B2 (en) 2005-04-07 2018-07-31 3M Innovative Properties Company System and method for tool feedback sensing
US20080009802A1 (en) * 2005-04-25 2008-01-10 Danilo Lambino Method of treating acne with stratum corneum piercing device
US20060253079A1 (en) * 2005-04-25 2006-11-09 Mcdonough Justin Stratum corneum piercing device
US20070270738A1 (en) * 2005-04-25 2007-11-22 Wu Jeffrey M Method of treating ACNE with stratum corneum piercing patch
US20060283465A1 (en) * 2005-06-16 2006-12-21 Nickel Janice H Smart drug delivery system and a method of implementation thereof
EP1904158B1 (en) 2005-06-24 2013-07-24 3M Innovative Properties Company Collapsible patch with microneedle array
DE602006016279D1 (de) 2005-06-27 2010-09-30 3M Innovative Properties Co Mikronadelkartuschenanordnung
EP2474338B1 (en) * 2005-06-27 2013-07-24 3M Innovative Properties Company Microneedle array applicator device
US20070060837A1 (en) * 2005-08-18 2007-03-15 Seoul National University Industry Foundation Barb-wired micro needle made of single crystalline silicon and biopsy method and medicine injecting method using the same
US8118753B2 (en) * 2005-08-18 2012-02-21 Seoul National University Industry Foundation Barb-wired micro needle made of single crystalline silicon and biopsy method and medicine injecting method using the same
DE102005040251A1 (de) * 2005-08-24 2007-03-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Transcorneales System zur Abgabe eines Arzneimittel-Wirkstoffes
AU2006287603B2 (en) * 2005-09-06 2012-05-10 Theraject, Inc. Solid solution perforator containing drug particle and/or drug-adsorbed particles
US9011473B2 (en) 2005-09-07 2015-04-21 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9358033B2 (en) * 2005-09-07 2016-06-07 Ulthera, Inc. Fluid-jet dissection system and method for reducing the appearance of cellulite
US8518069B2 (en) 2005-09-07 2013-08-27 Cabochon Aesthetics, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US10548659B2 (en) 2006-01-17 2020-02-04 Ulthera, Inc. High pressure pre-burst for improved fluid delivery
US9486274B2 (en) 2005-09-07 2016-11-08 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
EP1762259B2 (en) 2005-09-12 2025-01-01 Unomedical A/S Inserter for an infusion set with a first and second spring units
JP2009509659A (ja) * 2005-09-30 2009-03-12 Tti・エルビュー株式会社 生体界面への活性物質の送達のイオントフォレーシス装置及び方法
US20080262416A1 (en) * 2005-11-18 2008-10-23 Duan Daniel C Microneedle Arrays and Methods of Preparing Same
WO2007061964A1 (en) * 2005-11-18 2007-05-31 3M Innovative Properties Company Methods for coating microneedles
US9248317B2 (en) 2005-12-02 2016-02-02 Ulthera, Inc. Devices and methods for selectively lysing cells
US7885793B2 (en) 2007-05-22 2011-02-08 International Business Machines Corporation Method and system for developing a conceptual model to facilitate generating a business-aligned information technology solution
USD655807S1 (en) 2005-12-09 2012-03-13 Unomedical A/S Medical device
WO2007075614A1 (en) * 2005-12-21 2007-07-05 3M Innovative Properties Company Microneedle devices
EP2130560B1 (en) 2005-12-23 2013-08-07 Unomedical A/S device for administration
US20070191811A1 (en) * 2006-02-10 2007-08-16 Joseph Berglund System and Method for Treating a Vascular Condition
EP1988958B2 (en) 2006-02-28 2016-03-16 Unomedical A/S Inserter for infusion part
EP1996275A2 (en) * 2006-03-10 2008-12-03 Alza Corporation Microprojection array application with high barrier retainer
CN101401313B (zh) 2006-03-13 2014-06-11 诺沃—诺迪斯克有限公司 用于使用成双通信装置的电子设备的安全配对的系统
US9119945B2 (en) 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
EP2032188A1 (en) 2006-06-06 2009-03-11 Novo Nordisk A/S Assembly comprising skin-mountable device and packaging therefore
EP2023818A2 (en) 2006-06-07 2009-02-18 Unomedical A/S Inserter for transcutaneous sensor
CN101489604B (zh) 2006-06-09 2012-05-23 优诺医疗有限公司 安装垫
RU2443436C2 (ru) 2006-08-02 2012-02-27 Уномедикал А/С Канюльное и доставочное устройство
US20080058726A1 (en) * 2006-08-30 2008-03-06 Arvind Jina Methods and Apparatus Incorporating a Surface Penetration Device
EP2077882A2 (en) * 2006-10-25 2009-07-15 Nektar Therapeutics Powder dispersion apparatus, method of making and using the apparatus, and components that can be used on the apparatus and other devices
EP1917990A1 (en) 2006-10-31 2008-05-07 Unomedical A/S Infusion set
AU2008209537B2 (en) 2007-01-22 2013-01-31 Corium Pharma Solutions, Inc. Applicators for microneedle arrays
FR2912919B1 (fr) 2007-02-22 2009-05-01 Bernard Perriere Dispositif d'injection miniaturise a usage medical
EP2664323B1 (en) 2007-04-16 2020-07-29 Corium, Inc. Solvent-cast microneedle arrays containing active
US8439861B2 (en) 2007-04-24 2013-05-14 Velcro Industries B.V. Skin penetrating touch fasteners
US9186480B2 (en) 2007-06-20 2015-11-17 Unomedical A/S Apparatus for making a catheter
RU2010103450A (ru) 2007-07-03 2011-08-10 Уномедикал А/С (Dk) Устройство введения с бистабильными равновесными состояниями
DK2173410T3 (da) 2007-07-10 2011-06-06 Unomedical As Inserter med to fjedre
JP2010533524A (ja) 2007-07-18 2010-10-28 ウノメディカル アクティーゼルスカブ 枢動作用を持つ挿入デバイス
KR20090015449A (ko) * 2007-08-08 2009-02-12 현대자동차주식회사 수크로스 탄소 전구체로부터 결정성이 우수한 기공성그래파이트 탄소의 제조방법
US8439940B2 (en) 2010-12-22 2013-05-14 Cabochon Aesthetics, Inc. Dissection handpiece with aspiration means for reducing the appearance of cellulite
WO2009048607A1 (en) 2007-10-10 2009-04-16 Corium International, Inc. Vaccine delivery via microneedle arrays
JP2011502018A (ja) 2007-10-31 2011-01-20 ノボ・ノルデイスク・エー/エス 殺菌障壁としての無孔性材料
MX2010008759A (es) 2008-02-13 2010-08-31 Unomedical As Sellado entre una parte de canula y una trayectoria de fluido.
US9566384B2 (en) 2008-02-20 2017-02-14 Unomedical A/S Insertion device with horizontally moving part
EP2100850A1 (en) * 2008-03-11 2009-09-16 Stichting Voor De Technische Wetenschappen Microneedle array and a method for manufacturing microneedles
WO2009142741A1 (en) * 2008-05-21 2009-11-26 Theraject, Inc. Method of manufacturing solid solution peforator patches and uses thereof
BRPI0923489A2 (pt) 2008-12-22 2016-01-26 Unomedical As dispositivo médico compreendendo almofada adesiva
WO2010099321A1 (en) 2009-02-26 2010-09-02 The University Of North Carolina At Chapel Hill Interventional drug delivery system and associated methods
US20110006458A1 (en) * 2009-04-24 2011-01-13 Corium International, Inc. Methods for manufacturing microprojection arrays
EP2275164A1 (en) 2009-07-15 2011-01-19 Debiotech S.A. Multichannel micro-needles
AU2010277755A1 (en) 2009-07-30 2012-02-02 Unomedical A/S Inserter device with horizontal moving part
CN102497909B (zh) 2009-07-31 2014-10-29 3M创新有限公司 中空微针阵列
US11096708B2 (en) 2009-08-07 2021-08-24 Ulthera, Inc. Devices and methods for performing subcutaneous surgery
CN102548598B (zh) 2009-08-07 2014-09-17 犹诺医药有限公司 具有传感器和一个或多个插管的传送装置
US9358064B2 (en) 2009-08-07 2016-06-07 Ulthera, Inc. Handpiece and methods for performing subcutaneous surgery
US8062568B2 (en) * 2009-08-27 2011-11-22 Korea University Research And Business Foundation Nano pattern writer
HU227748B1 (en) 2009-09-21 2012-02-28 Zoltan Dr Piros Microinfusion device for dosing insuline in the treatment of diabetes
US20110144591A1 (en) * 2009-12-11 2011-06-16 Ross Russell F Transdermal Delivery Device
JP5650241B2 (ja) 2009-12-16 2015-01-07 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company 自己注射装置
ES2565405T3 (es) 2009-12-16 2016-04-04 Becton Dickinson And Company Dispositivo de autoinyección
ES2860755T3 (es) 2009-12-16 2021-10-05 Becton Dickinson Co Dispositivo de auto inyección
JP5894082B2 (ja) 2009-12-16 2016-03-23 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company 自己注射装置
JP5650243B2 (ja) 2009-12-16 2015-01-07 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company 自己注射装置
WO2011075102A1 (en) 2009-12-16 2011-06-23 Becton, Dickinson And Company Self- injection device
JP2013523233A (ja) 2010-03-30 2013-06-17 ウノメディカル アクティーゼルスカブ 医療デバイス
CA2797205C (en) 2010-04-28 2019-04-16 Kimberly-Clark Worldwide, Inc. Medical devices for delivery of sirna
AU2011311255B2 (en) 2010-04-28 2015-10-08 Sorrento Therapeutics, Inc. Method for increasing permeability of an epithelial barrier
RU2585159C2 (ru) 2010-04-28 2016-05-27 Кимберли-Кларк Ворлдвайд, Инк. Устройство доставки лекарственного средства, применяемого при ревматоидном артрите
KR101794377B1 (ko) 2010-04-28 2017-11-06 킴벌리-클라크 월드와이드, 인크. 나노구조체를 포함하는 복합형 마이크로니들 어레이
WO2011140274A2 (en) 2010-05-04 2011-11-10 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
US9125625B2 (en) 2010-06-10 2015-09-08 The Regents Of The University Of California Textile-based printable electrodes for electrochemical sensing
CN101905856B (zh) * 2010-06-11 2012-10-10 北京大学 一种用于透皮给药的平面空心微针的制备方法
DE102010038733A1 (de) * 2010-07-30 2012-02-02 Robert Bosch Gmbh Modulare Mikronadel-Transportvorrichtung
JP5718622B2 (ja) * 2010-08-31 2015-05-13 Asti株式会社 マイクロニードルアレイ装置
CN103153360B (zh) 2010-09-02 2016-04-06 贝克顿·迪金森公司 具有带激活阻止器的针盖的自注射装置
WO2012038959A2 (en) * 2010-09-21 2012-03-29 Israel Shamir Lebovitz Multi-directional needle
EP2433663A1 (en) 2010-09-27 2012-03-28 Unomedical A/S Insertion system
EP2436412A1 (en) 2010-10-04 2012-04-04 Unomedical A/S A sprinkler cannula
WO2012057270A1 (ja) * 2010-10-27 2012-05-03 Asti株式会社 マイクロニードルアレイ装着用治具とマイクロニードルアレイ装置
CN102641549B (zh) * 2011-02-18 2016-05-04 帕洛阿尔托研究中心公司 包括微针的透粘膜药物输送装置和方法
US8696637B2 (en) 2011-02-28 2014-04-15 Kimberly-Clark Worldwide Transdermal patch containing microneedles
KR101241059B1 (ko) * 2011-03-04 2013-03-11 연세대학교 산학협력단 마이크로 니들을 이용한 혈관외벽 장착 약물 전달장치 및 약물 전달방법
US8636696B2 (en) 2011-06-10 2014-01-28 Kimberly-Clark Worldwide, Inc. Transdermal device containing microneedles
US9352084B2 (en) * 2011-08-05 2016-05-31 Unitract Syringe Pty Ltd Injectable drug delivery arrangement with controlled delivery cannula position relative to point of delivery
AU2012326664A1 (en) 2011-09-02 2014-04-03 North Carolina State University Microneedle arrays for biosensing and drug delivery
CN103957962B (zh) 2011-10-05 2017-07-07 犹诺医药有限公司 用于同时插入多个经皮部分的插入物
EP2583715A1 (en) 2011-10-19 2013-04-24 Unomedical A/S Infusion tube system and method for manufacture
HUE058275T2 (hu) 2011-10-27 2022-07-28 Sorrento Therapeutics Inc Beültethetõ eszközök biológiailag hatásos szerek tobábbítására
US9550053B2 (en) 2011-10-27 2017-01-24 Kimberly-Clark Worldwide, Inc. Transdermal delivery of high viscosity bioactive agents
US20170246439A9 (en) 2011-10-27 2017-08-31 Kimberly-Clark Worldwide, Inc. Increased Bioavailability of Transdermally Delivered Agents
US9440051B2 (en) 2011-10-27 2016-09-13 Unomedical A/S Inserter for a multiplicity of subcutaneous parts
JP5845808B2 (ja) * 2011-10-28 2016-01-20 凸版印刷株式会社 マイクロニードルデバイスおよびその製造方法
JP5788019B2 (ja) * 2011-11-18 2015-09-30 南部化成株式会社 経皮投薬装置
WO2014100750A1 (en) 2012-12-21 2014-06-26 Corium International, Inc. Microarray for delivery of therapeutic agent and methods of use
AU2014207944A1 (en) 2013-01-21 2015-07-23 Bukyoung Pharm Co., Ltd. Microneedle, mould for producing same, and production method for same
CN103157178B (zh) * 2013-02-05 2014-12-31 北京化工大学 精确控制微针插入长度的印章式工具
WO2014164314A1 (en) 2013-03-12 2014-10-09 Corium International, Inc. Microprojection applicators
EP2968116A1 (en) 2013-03-15 2016-01-20 Corium International, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
CA2903583C (en) 2013-03-15 2021-12-28 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
EP4194028A1 (en) 2013-03-15 2023-06-14 Corium Pharma Solutions, Inc. Multiple impact microprojection applicators
KR102341601B1 (ko) 2013-03-15 2021-12-21 코리움, 인크. 치료제를 전달하기 위한 마이크로어레이 및 사용 방법
EP3027263A1 (en) 2013-07-30 2016-06-08 ZP Opco, Inc. Low-profile microneedle patch applicator
US9987427B1 (en) 2014-06-24 2018-06-05 National Technology & Engineering Solutions Of Sandia, Llc Diagnostic/drug delivery “sense-respond” devices, systems, and uses thereof
EP2974758A1 (de) * 2014-07-15 2016-01-20 LTS LOHMANN Therapie-Systeme AG Zylinder-Kolben-Einheit mit Kanülen
WO2016036866A1 (en) 2014-09-04 2016-03-10 Corium International, Inc. Microstructure array, methods of making, and methods of use
JP5967595B2 (ja) * 2014-09-08 2016-08-10 株式会社かいわ 穿刺器具
NL2013654B1 (nl) * 2014-10-20 2016-08-11 Helène Tamara Witteman Amber Draagbare injectie-inrichting voor draagbare bevestiging aan een lichaamsdeel, voor het in een draagtoestand injecteren van een geneesmiddel via de huid van het lichaamsdeel.
JP6906885B2 (ja) 2014-11-14 2021-07-21 ロレアル しわを減少させるためのマイクロニードルシート
CN104307098B (zh) * 2014-11-15 2016-09-07 唐晨 微针给药装置及其制造方法
EP3235539B1 (en) * 2014-12-16 2024-06-05 Juvic Inc. Microcellular microstructure and method for manufacturing same
JP6766802B2 (ja) * 2015-02-16 2020-10-14 凸版印刷株式会社 マイクロニードル
CN107405477B (zh) * 2015-03-18 2020-06-16 凸版印刷株式会社 药剂施予装置及药剂施予装置的制造方法
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
CN108601932A (zh) * 2016-01-28 2018-09-28 株式会社理光 微针阵列和微针片
JP2017176652A (ja) 2016-03-31 2017-10-05 花王株式会社 微細中空突起具
CN105963855A (zh) * 2016-06-22 2016-09-28 成都市亿泰科技有限公司 一种含分离式储药囊的微针给药贴片
CN105999533B (zh) * 2016-06-30 2022-01-25 山东中医药大学附属医院 药物夹层敷贴袋
US12109032B1 (en) 2017-03-11 2024-10-08 Biolinq Incorporated Methods for achieving an isolated electrical interface between an anterior surface of a microneedle structure and a posterior surface of a support structure
US11045142B1 (en) 2017-04-29 2021-06-29 Biolinq, Inc. Heterogeneous integration of silicon-fabricated solid microneedle sensors and CMOS circuitry
WO2019036609A1 (en) * 2017-08-17 2019-02-21 New York University BONE GROWTH STIMULATOR AND METHODS OF USE
TWI666036B (zh) * 2017-10-27 2019-07-21 研能科技股份有限公司 穿戴式人體胰島素注入供液裝置
TWI657842B (zh) * 2017-10-27 2019-05-01 研能科技股份有限公司 人體胰島素注入之供液裝置
TWI656893B (zh) 2017-10-27 2019-04-21 研能科技股份有限公司 穿戴式人體胰島素注入供液裝置
US11844919B2 (en) * 2018-01-03 2023-12-19 The Trustees Of Columbia University In The City Of New York Microneedle for local delivery of therapeutic agent
JP7305311B2 (ja) 2018-05-30 2023-07-10 ロレアル マイクロニードルシート
JP2020002084A (ja) 2018-06-29 2020-01-09 ロレアル マイクロニードルシートを使用する美容方法
JP7335061B2 (ja) 2018-06-29 2023-08-29 ロレアル マイクロニードルシートを使用する美容方法
JP2020018327A (ja) 2018-07-17 2020-02-06 ロレアル マイクロニードルシート
JP2020099513A (ja) 2018-12-21 2020-07-02 ロレアル マイクロニードルシートを使用するキット及び美容方法
US20220134072A1 (en) * 2019-03-19 2022-05-05 King Abdullah University Of Science And Technology Miniaturized delivery system and method
CN110478613B (zh) * 2019-08-22 2022-08-09 京东方科技集团股份有限公司 递送制剂的器件、设备及器件中针头阵列的制备方法
JP2021094146A (ja) 2019-12-16 2021-06-24 ロレアル マイクロニードルシートを使用する美容方法
JP2023514926A (ja) * 2019-12-20 2023-04-12 アレス トレーディング ソシエテ アノニム マイクロニードルアレイ、アクチュエータ及び使用方法
EP3854375A1 (en) 2020-01-23 2021-07-28 Paean Aesthetics Inc Micro-spicule composition to control its shape and method for producing the same
CN115551584A (zh) 2020-06-17 2022-12-30 莱雅公司 使用微针片的套件和美容方法
FR3113843B1 (fr) 2020-09-07 2024-03-15 Oreal Kit et traitement cosmetique utilisant une feuille de micro-aiguilles
GB2631618A (en) 2020-07-29 2025-01-08 Biolinq Incorporated Continuous analyte monitoring system with microneedle array
DE102020133395A1 (de) 2020-12-14 2022-06-15 Lts Lohmann Therapie-Systeme Ag. Wirkstoffabgabesystem
US12161832B2 (en) 2021-03-01 2024-12-10 Deka Products Limited Partnership Medical agent dispensing systems, methods, and apparatuses
JP7341583B6 (ja) 2021-05-08 2023-09-29 バイオリンク インコーポレイテッド 微小針アレイベースの持続的分析物監視デバイスのための障害検出
FR3135206A1 (fr) 2022-05-05 2023-11-10 L'oreal Processus cosmétique utilisant une feuille de micro-aiguilles
FR3139007A1 (fr) 2022-08-23 2024-03-01 L'oreal Composition convenant pour des traitements cosmétiques de substance kératineuse
KR20240043210A (ko) * 2022-09-26 2024-04-03 주식회사 케이티앤지 에멀전을 방출하는 전자 장치 및 그의 동작 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US4622031A (en) * 1983-08-18 1986-11-11 Drug Delivery Systems Inc. Indicator for electrophoretic transcutaneous drug delivery device
GB2221394B (en) * 1988-08-05 1992-03-04 Eilert Eilertsen An injection device
CA2149836C (en) * 1994-05-23 1999-07-06 Sang Bae Choi Perforating device for dermal administration

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EP0840634B1 (de) 2001-10-31
AU722943B2 (en) 2000-08-17
HUP9802773A2 (en) 1999-06-28
JPH11509123A (ja) 1999-08-17
PL181658B1 (pl) 2001-08-31
AR004499A1 (es) 1998-12-16
NZ313984A (en) 2000-04-28
ATE207769T1 (de) 2001-11-15
TW375528B (en) 1999-12-01
NO980147D0 (no) 1998-01-13
NO980147L (no) 1998-03-13
CZ290458B6 (cs) 2002-07-17
CN1190904A (zh) 1998-08-19
UA62918C2 (en) 2004-01-15
EE04006B1 (et) 2003-04-15

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