RU96107098A - Фармацевтический препарат для блокирования отложения микроорганизмов на клетках млекопитающих - Google Patents
Фармацевтический препарат для блокирования отложения микроорганизмов на клетках млекопитающих Download PDFInfo
- Publication number
- RU96107098A RU96107098A RU96107098/4A RU96107098A RU96107098A RU 96107098 A RU96107098 A RU 96107098A RU 96107098/4 A RU96107098/4 A RU 96107098/4A RU 96107098 A RU96107098 A RU 96107098A RU 96107098 A RU96107098 A RU 96107098A
- Authority
- RU
- Russia
- Prior art keywords
- degree
- galacturonide
- polymerization
- drug according
- microorganisms
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title claims abstract 5
- 230000000903 blocking effect Effects 0.000 title claims 4
- 244000005700 microbiome Species 0.000 title claims 4
- 241000124008 Mammalia Species 0.000 title 1
- 229940127557 pharmaceutical product Drugs 0.000 title 1
- 238000006116 polymerization reaction Methods 0.000 claims abstract 10
- 230000032050 esterification Effects 0.000 claims abstract 5
- 238000005886 esterification reaction Methods 0.000 claims abstract 5
- 210000004962 mammalian cell Anatomy 0.000 claims abstract 3
- 239000003085 diluting agent Substances 0.000 claims abstract 2
- 239000003937 drug carrier Substances 0.000 claims abstract 2
- 239000000945 filler Substances 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims 8
- 229940079593 drug Drugs 0.000 claims 8
- 230000008021 deposition Effects 0.000 claims 2
- 230000001580 bacterial effect Effects 0.000 claims 1
- 229940088623 biologically active substance Drugs 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 210000002345 respiratory system Anatomy 0.000 claims 1
- 239000013543 active substance Substances 0.000 abstract 1
- 244000052616 bacterial pathogen Species 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Claims (14)
1. Фармацевтический препарат для блокирования отложения микроорганизмов на клетках млекопитающих, отличающийся тем, что он в качестве биологически активного вещества содержит один или несколько галактуронидов со степенью полимеризации ≥ 2 и степенью этерификации менее 20%, в данном случае вместе с фармацевтически употребительными носителями, разбавителями, вспомогательными веществами и наполнителями.
2. Препарат по п.1, отличающийся тем, что степень этерификации галактуронида <10%.
3. Препарат по п.1 или 2, отличающийся тем, что степень этерификации галактуронида <5%.
4. Препарат по одному из пп.1-3, отличающийся тем, что степень полимеризации галактуронида равна 2-7.
5. Препарат по одному из пп.1-4, отличающийся тем, что степень полимеризации галактуронида равна 2-6.
6. Препарат по одному из пп.1-5, отличающийся тем, что степень полимеризации галактуронида составляет 2-5.
7. Препарат по одному из пп.1-6, отличающийся тем, что степень полимеризации галактуронида равна 2-4.
8. Препарат по одному из пп.1-7, отличающийся тем, что степень полимеризации галактуронида равна 2-3.
9. Препарат по одному из пп.1-8, отличающийся тем, что степень полимеризации галактуронида равна 2.
10. Применение галактуронидов со степенью полимеризации ≥ 2 для получения фармацевтического препарата для блокирования отложения микроорганизмов на клетках млекопитающих.
11. Применение по п.10 для получения фармацевтического препарата для лечения инфекций кишечно-желудочного тракта, кровяной системы, дыхательных путей, урогенитального тракта или/и полости носоглотки.
12. Применение по п.10 или 11 для блокирования отложений бактериальных микроорганизмов.
13. Применение по одному из пп.10-12, отличающееся тем, что степень этерификации галактуронида < 20%.
14. Применение по одному из пп.1-13, отличающееся тем, что степень полимеризации галактуронида равна 2-4.0
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEP4330773.6 | 1993-09-10 | ||
| DE4330773A DE4330773A1 (de) | 1993-09-10 | 1993-09-10 | Blockierung der Anlagerung von Keimen an menschliche Zellen |
| PCT/EP1994/003006 WO1995007084A1 (de) | 1993-09-10 | 1994-09-08 | Blockierung der anlagerung von keimen an menschliche zellen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU96107098A true RU96107098A (ru) | 1998-07-27 |
Family
ID=6497409
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU96107098/4A RU96107098A (ru) | 1993-09-10 | 1994-09-08 | Фармацевтический препарат для блокирования отложения микроорганизмов на клетках млекопитающих |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5683991A (ru) |
| EP (1) | EP0716605B1 (ru) |
| JP (1) | JP3798425B2 (ru) |
| AT (1) | ATE174222T1 (ru) |
| AU (1) | AU679262B2 (ru) |
| CA (1) | CA2171197A1 (ru) |
| CZ (1) | CZ288050B6 (ru) |
| DE (2) | DE4330773A1 (ru) |
| DK (1) | DK0716605T3 (ru) |
| ES (1) | ES2127940T3 (ru) |
| GR (1) | GR3029619T3 (ru) |
| HU (1) | HU223043B1 (ru) |
| PL (1) | PL313393A1 (ru) |
| RU (1) | RU96107098A (ru) |
| SK (1) | SK282305B6 (ru) |
| WO (1) | WO1995007084A1 (ru) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19503423A1 (de) * | 1995-02-03 | 1996-08-08 | Beiersdorf Ag | Antiadhäsive Wirkstoffe |
| US5951965A (en) * | 1998-08-28 | 1999-09-14 | Colgate Palmolive Company | Method for visually demonstrating the effectiveness of an anti-bacteria attachment composition |
| AU730929B2 (en) * | 1999-07-06 | 2001-03-22 | Nestec S.A. | Composition and method for prolonging the useful life of enteral feeding tubes |
| DE10006989A1 (de) * | 2000-02-16 | 2001-08-23 | Nutricia Nv | Antiadhäsive Kohlenhydratmischung |
| DE10057976B4 (de) | 2000-11-22 | 2005-02-03 | Südzucker AG Mannheim/Ochsenfurt | Verfahren zur Herstellung von Pektinhydrolyseprodukten |
| DE10061574A1 (de) * | 2000-12-11 | 2002-06-13 | Josef Peter Guggenbichler | Blockierung der Anlagerung von Keimen bei Vögeln |
| FR2831819B1 (fr) * | 2001-11-08 | 2004-09-03 | Rocher Yves Biolog Vegetale | Utilisation d'oligosaccharides dans des compositions cosmetiques ou dermatologiques pour stimuler l'adhesion de keratinocytes sur les proteines majeures de la jonction dermo-epidermique |
| FR2852242B1 (fr) * | 2003-03-13 | 2007-09-14 | Utilisation d'oligogalacturonides en cosmetique ou pour la preparation d'une composition dermatologique ou pharmaceutique | |
| GB0321996D0 (en) | 2003-09-19 | 2003-10-22 | Novartis Nutrition Ag | Organic compounds |
| US8110215B2 (en) * | 2004-04-30 | 2012-02-07 | Kimberly-Clark Worldwide, Inc. | Personal care products and methods for inhibiting the adherence of flora to skin |
| EA200700467A1 (ru) * | 2004-08-18 | 2007-12-28 | БАЙОЛОДЖИК ХЕЛС СОЛУШЕНС ПиТиУай ЭлТиДи | Композиция из растений (варианты), фармацевтическая композиция на ее основе и способ профилактики и лечения нарушения мочеполовых функций |
| GB2430881B (en) * | 2005-10-06 | 2010-10-13 | Ntnu Technology Transfer As | Oligoelectrolyte polyols for the treatment of mucosal hyperviscosity |
| GB0707096D0 (en) * | 2007-04-12 | 2007-05-23 | Ntnu Technology Transfer As | Method |
| DK2268142T3 (en) | 2007-11-27 | 2017-05-22 | Algipharma As | USING ALGINATED OLIGOMERS TO FIGHT BIOFILM |
| GB0904942D0 (en) | 2009-03-23 | 2009-05-06 | Ntnu Technology Transfer As | Composition |
| GB0904941D0 (en) | 2009-03-23 | 2009-05-06 | Ntnu Technology Transfer As | Composition |
| EP2437784B8 (en) | 2009-06-03 | 2013-12-11 | Algipharma As | Alginate oligomers for use in overcoming multidrug resistance in bacteria |
| GB0909529D0 (en) * | 2009-06-03 | 2009-07-15 | Algipharma Ipr As | Alginate oligomers for the inhibition of microbial adherence to surfaces |
| WO2011060474A1 (de) | 2009-11-20 | 2011-05-26 | Erber Aktiengesellschaft | Verfahren zur herstellung eines futtermittelzusatzes sowie futtermittelzusatz |
| EP3054998A1 (en) * | 2013-08-28 | 2016-08-17 | The Procter & Gamble Company | Substrate comprising oligogalacturonides and disposable absorbent article comprising the substrate |
| DE102013022109A1 (de) * | 2013-12-27 | 2015-07-02 | Markus Paulmichl | Oligo-(2-7)-Glucuronat umfassendes Medikament (zweite medizinische Indikation) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2987448A (en) * | 1959-12-11 | 1961-06-06 | Oil Seed Products Inc | Recovery of galacturonic acid |
| US4521592A (en) * | 1981-10-23 | 1985-06-04 | Svenska Sockerfabriks Ab | Compounds for therapeutic or diagnostic use, a process and intermediates for their preparation |
| US4885128A (en) * | 1985-07-30 | 1989-12-05 | Janez Megusar | Method for improving performance of irradiated structural materials |
| GB8803157D0 (en) * | 1988-02-11 | 1988-03-09 | Nat Res Dev | Denture protection |
| US5055455A (en) * | 1988-09-28 | 1991-10-08 | Brigham And Women's Hospital | Capsular polysaccharide adhesin antigen, preparation, purification and use |
| WO1991016449A1 (en) * | 1990-04-16 | 1991-10-31 | The Trustees Of The University Of Pennsylvania | Saccharide compositions, methods and apparatus for their synthesis |
| US5523014A (en) * | 1994-05-16 | 1996-06-04 | Gojo Industries, Inc. | Flowable, pumpable cleaning compositions and method for the preparation thereof |
-
1993
- 1993-09-10 DE DE4330773A patent/DE4330773A1/de not_active Withdrawn
-
1994
- 1994-09-08 CA CA002171197A patent/CA2171197A1/en not_active Abandoned
- 1994-09-08 ES ES94927587T patent/ES2127940T3/es not_active Expired - Lifetime
- 1994-09-08 EP EP94927587A patent/EP0716605B1/de not_active Expired - Lifetime
- 1994-09-08 DE DE59407457T patent/DE59407457D1/de not_active Expired - Fee Related
- 1994-09-08 CZ CZ1996708A patent/CZ288050B6/cs not_active IP Right Cessation
- 1994-09-08 WO PCT/EP1994/003006 patent/WO1995007084A1/de active IP Right Grant
- 1994-09-08 AU AU76956/94A patent/AU679262B2/en not_active Ceased
- 1994-09-08 DK DK94927587T patent/DK0716605T3/da active
- 1994-09-08 JP JP50846295A patent/JP3798425B2/ja not_active Expired - Fee Related
- 1994-09-08 HU HU9600602A patent/HU223043B1/hu not_active IP Right Cessation
- 1994-09-08 SK SK329-96A patent/SK282305B6/sk not_active IP Right Cessation
- 1994-09-08 PL PL94313393A patent/PL313393A1/xx unknown
- 1994-09-08 RU RU96107098/4A patent/RU96107098A/ru not_active Application Discontinuation
- 1994-09-08 AT AT94927587T patent/ATE174222T1/de not_active IP Right Cessation
-
1996
- 1996-03-08 US US08/613,991 patent/US5683991A/en not_active Expired - Fee Related
-
1999
- 1999-03-08 GR GR990400706T patent/GR3029619T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH09502195A (ja) | 1997-03-04 |
| EP0716605A1 (de) | 1996-06-19 |
| CA2171197A1 (en) | 1995-03-16 |
| WO1995007084A1 (de) | 1995-03-16 |
| JP3798425B2 (ja) | 2006-07-19 |
| AU7695694A (en) | 1995-03-27 |
| PL313393A1 (en) | 1996-06-24 |
| HU9600602D0 (en) | 1996-05-28 |
| US5683991A (en) | 1997-11-04 |
| ATE174222T1 (de) | 1998-12-15 |
| SK32996A3 (en) | 1997-03-05 |
| CZ70896A3 (en) | 1996-10-16 |
| SK282305B6 (sk) | 2002-01-07 |
| EP0716605B1 (de) | 1998-12-09 |
| ES2127940T3 (es) | 1999-05-01 |
| DK0716605T3 (da) | 1999-08-16 |
| AU679262B2 (en) | 1997-06-26 |
| GR3029619T3 (en) | 1999-06-30 |
| DE59407457D1 (de) | 1999-01-21 |
| DE4330773A1 (de) | 1995-03-16 |
| HUT74431A (en) | 1996-12-30 |
| CZ288050B6 (cs) | 2001-04-11 |
| HU223043B1 (hu) | 2004-03-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU96107098A (ru) | Фармацевтический препарат для блокирования отложения микроорганизмов на клетках млекопитающих | |
| NZ506058A (en) | Antibacterial 9-substituted tetracyclines, and pharmaceuticals and uses thereof | |
| ATE206716T1 (de) | Cyclische wirkstoff-vorläufer verbindungen von peptiden und peptid-nukleicsäuren mit verbesserter metabolischer stabilität und zellmembran permeabilität | |
| DZ1877A1 (fr) | Forme posologiques d'azithromycine pour le traitement d'infection microbiennes. | |
| BG101118A (en) | Therapeutical compounds | |
| CA2031803A1 (en) | Improvements in or relating to glycopeptide deriveratives | |
| ZA952555B (en) | Lipopeptide derivatives a process for their preparation and their use | |
| ATE258057T1 (de) | Therapeutische und diagnostische agenzien zur behandlung mikrobieller infektionen | |
| DE69430385D1 (de) | Hiv-proteaseinhibitoren | |
| ATE78490T1 (de) | Glykopeptid-antibiotika. | |
| ATE259654T1 (de) | Pharmazeutische präparate zur bekämpfung oder prophylaxe von mikroorganismen infizierten oberflächen | |
| PT866791E (pt) | Diaminopirimidinas formulacoes farmaceuticas que as contem e sua utilizacao antibacteriana | |
| ES2159733T3 (es) | Compuestos de dialquiltiacumicina. | |
| EA200100700A1 (ru) | Гены и белки и их применение | |
| NO174258C (no) | Analogifremgangsmåte for fremstilling av terapeutisk aktive, krystallinske cefemsyreaddisjonssalter | |
| AU5643299A (en) | Humic acid and its use in the treatment of various conditions | |
| ITMI913493A1 (it) | Dispositivo per la disinfezione o la immunizzazione di zone del corpo umano esposte al contagio, da germi, batteri e virus | |
| ATE71299T1 (de) | Pharmazeutische zubereitung zur behandlung bakterieller infektionen. | |
| AU6304000A (en) | Vaccine | |
| ATE164764T1 (de) | T-lymphozyten enthaltende pharmazeutische zusammensetzung zur behandlung von infektionen | |
| RU2003121020A (ru) | Блокирование накопления микроорганизмов у птиц | |
| EP0281092A3 (de) | Cephalosporinderivate und Verfahren zu ihrer Herstellung | |
| UA28523A (ru) | Способ ингибирования репродукции вируса иммунодефицита человека | |
| AP9701040A0 (en) | Novel compounds. | |
| RU93057110A (ru) | Способ аппендэктомии |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA93 | Acknowledgement of application withdrawn (no request for examination) |
Effective date: 20050111 |