RS61718B1 - Oksisteroli i postupci za njihovu upotrebu - Google Patents
Oksisteroli i postupci za njihovu upotrebuInfo
- Publication number
- RS61718B1 RS61718B1 RS20210461A RSP20210461A RS61718B1 RS 61718 B1 RS61718 B1 RS 61718B1 RS 20210461 A RS20210461 A RS 20210461A RS P20210461 A RSP20210461 A RS P20210461A RS 61718 B1 RS61718 B1 RS 61718B1
- Authority
- RS
- Serbia
- Prior art keywords
- oxysterols
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
- C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Anesthesiology (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562189048P | 2015-07-06 | 2015-07-06 | |
US201662280394P | 2016-01-19 | 2016-01-19 | |
EP16821924.4A EP3319611B1 (en) | 2015-07-06 | 2016-07-06 | Oxysterols and methods of use thereof |
PCT/US2016/041168 WO2017007836A1 (en) | 2015-07-06 | 2016-07-06 | Oxysterols and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
RS61718B1 true RS61718B1 (sr) | 2021-05-31 |
Family
ID=57686105
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RS20210461A RS61718B1 (sr) | 2015-07-06 | 2016-07-06 | Oksisteroli i postupci za njihovu upotrebu |
Country Status (30)
Country | Link |
---|---|
US (4) | US10201550B2 (sr) |
EP (2) | EP3319611B1 (sr) |
JP (4) | JP2018519351A (sr) |
KR (2) | KR20240137111A (sr) |
CN (2) | CN113292623A (sr) |
AU (3) | AU2016289967B2 (sr) |
BR (2) | BR112018000129B1 (sr) |
CA (1) | CA2991214C (sr) |
CO (1) | CO2018000660A2 (sr) |
CY (1) | CY1124496T1 (sr) |
DK (2) | DK3319611T3 (sr) |
ES (1) | ES2865258T3 (sr) |
FI (1) | FI3828194T3 (sr) |
HR (1) | HRP20210526T8 (sr) |
HU (1) | HUE053778T2 (sr) |
IL (2) | IL305404A (sr) |
LT (1) | LT3319611T (sr) |
MA (2) | MA42410B1 (sr) |
MD (1) | MD3319611T2 (sr) |
MX (2) | MX390302B (sr) |
PE (1) | PE20180483A1 (sr) |
PH (2) | PH12021551134A1 (sr) |
PL (1) | PL3319611T3 (sr) |
PT (1) | PT3319611T (sr) |
RS (1) | RS61718B1 (sr) |
RU (2) | RU2744267C2 (sr) |
SG (1) | SG10202010553XA (sr) |
SI (1) | SI3319611T1 (sr) |
SM (1) | SMT202100226T1 (sr) |
WO (1) | WO2017007836A1 (sr) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SMT202300232T1 (it) | 2011-09-08 | 2023-09-06 | Sage Therapeutics Inc | Steroidi neuroattivi, composizioni e relativi usi |
JP6255082B2 (ja) | 2013-03-13 | 2017-12-27 | セージ セラピューティクス, インコーポレイテッド | 神経刺激性ステロイドおよびその使用方法 |
EP3157528B1 (en) | 2014-06-18 | 2023-09-13 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
WO2016007762A1 (en) | 2014-07-09 | 2016-01-14 | Duke University | Compositions and methods for the repair of myelin |
SG10202002655VA (en) | 2015-07-06 | 2020-05-28 | Sage Therapeutics Inc | Oxysterols and methods of use thereof |
LT3319611T (lt) | 2015-07-06 | 2021-05-10 | Sage Therapeutics, Inc. | Oksisteroliai ir jų naudojimo būdai |
EP4316591A3 (en) | 2015-07-06 | 2024-04-24 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
WO2017173358A1 (en) * | 2016-04-01 | 2017-10-05 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
WO2017193046A1 (en) | 2016-05-06 | 2017-11-09 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
JP6966486B2 (ja) | 2016-07-07 | 2021-11-17 | セージ セラピューティクス, インコーポレイテッド | オキシステロールおよびその使用方法 |
EP3519422B1 (en) | 2016-09-30 | 2022-08-31 | Sage Therapeutics, Inc. | C7 substituted oxysterols and these compounds for use as nmda modulators |
MX2019004578A (es) | 2016-10-18 | 2019-10-09 | Sage Therapeutics Inc | Oxisteroles y metodos de uso de los mismos. |
RU2019115112A (ru) | 2016-10-18 | 2020-11-24 | Сейдж Терапьютикс, Инк. | Оксистеролы и способы их применения |
EP4537847A3 (en) * | 2017-01-13 | 2025-07-30 | Duke University | Compositions and methods for the treatment of myelin related and inflammation related diseases or disorders |
US10857163B1 (en) | 2019-09-30 | 2020-12-08 | Athenen Therapeutics, Inc. | Compositions that preferentially potentiate subtypes of GABAA receptors and methods of use thereof |
WO2022261510A1 (en) | 2021-06-11 | 2022-12-15 | Sage Therapeutics, Inc. | Neuroactive steroid for the treatment of alzheimer's disease |
CN113667734B (zh) * | 2021-07-16 | 2022-05-24 | 四川大学华西医院 | Shank3片段序列甲基化检测试剂在制备精神分裂症诊断试剂盒中的用途 |
WO2023028278A2 (en) * | 2021-08-25 | 2023-03-02 | Sage Therapeutics, Inc. | Positive nmda-modulating compounds and methods of use thereof |
WO2023083979A1 (en) * | 2021-11-10 | 2023-05-19 | Umecrine Ab | 3.beta.-hydroxy, 3.alpha.-ethyl steroids for modulation of the alpha-3 subtype of the gaba-a receptor |
WO2023114224A1 (en) | 2021-12-13 | 2023-06-22 | Sage Therapeutics, Inc. | Combination of muscarinic receptor positive modulators and nmda positive allosteric modulators |
CN116514893A (zh) * | 2022-01-28 | 2023-08-01 | 珂阑(上海)医药科技有限公司 | 甾类化合物、其制备方法和应用 |
WO2024229297A1 (en) * | 2023-05-02 | 2024-11-07 | Sage Therapeutics, Inc. | Lymphatic system-targeting compounds |
TW202508555A (zh) * | 2023-07-27 | 2025-03-01 | 大陸商珂闌(上海)醫藥科技有限公司 | 甾類化合物、其製備方法和應用 |
WO2025020190A1 (zh) * | 2023-07-27 | 2025-01-30 | 珂阑(上海)医药科技有限公司 | 甾类化合物、其制备方法和应用 |
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