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RS61412B1 - Anti-tnf alfa-antitela i njihovi funkcionalni fragmenti - Google Patents

Anti-tnf alfa-antitela i njihovi funkcionalni fragmenti

Info

Publication number
RS61412B1
RS61412B1 RS20210140A RSP20210140A RS61412B1 RS 61412 B1 RS61412 B1 RS 61412B1 RS 20210140 A RS20210140 A RS 20210140A RS P20210140 A RSP20210140 A RS P20210140A RS 61412 B1 RS61412 B1 RS 61412B1
Authority
RS
Serbia
Prior art keywords
antibodies
functional fragments
tnf alpha
tnf
alpha
Prior art date
Application number
RS20210140A
Other languages
English (en)
Inventor
Tea Gunde
Sebastian Meyer
Esther Maria Furrer
Original Assignee
Tillotts Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tillotts Pharma Ag filed Critical Tillotts Pharma Ag
Publication of RS61412B1 publication Critical patent/RS61412B1/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241Tumor Necrosis Factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/626Diabody or triabody
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
RS20210140A 2016-03-17 2016-03-17 Anti-tnf alfa-antitela i njihovi funkcionalni fragmenti RS61412B1 (sr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16160918.5A EP3219727B1 (en) 2016-03-17 2016-03-17 Anti-tnf alpha-antibodies and functional fragments thereof

Publications (1)

Publication Number Publication Date
RS61412B1 true RS61412B1 (sr) 2021-03-31

Family

ID=55542579

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20210140A RS61412B1 (sr) 2016-03-17 2016-03-17 Anti-tnf alfa-antitela i njihovi funkcionalni fragmenti

Country Status (27)

Country Link
US (1) US10975143B2 (sr)
EP (2) EP3219727B1 (sr)
JP (1) JP7126485B2 (sr)
KR (1) KR102474765B1 (sr)
CN (1) CN109071651B (sr)
AR (1) AR107916A1 (sr)
BR (1) BR112018067713A2 (sr)
CA (1) CA3011786A1 (sr)
CY (1) CY1123781T1 (sr)
DK (1) DK3219727T3 (sr)
EA (1) EA201892097A1 (sr)
ES (1) ES2843974T3 (sr)
HR (1) HRP20210120T1 (sr)
HU (1) HUE052869T2 (sr)
IL (1) IL261140B2 (sr)
JO (1) JOP20170063B1 (sr)
LT (1) LT3219727T (sr)
MA (1) MA43738A (sr)
PL (1) PL3219727T3 (sr)
PT (1) PT3219727T (sr)
RS (1) RS61412B1 (sr)
SG (1) SG11202000029PA (sr)
SI (1) SI3219727T1 (sr)
SM (1) SMT202000703T1 (sr)
TW (1) TWI758280B (sr)
UY (1) UY37158A (sr)
WO (1) WO2017158097A1 (sr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
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EA039201B1 (ru) 2016-03-17 2021-12-16 Нумаб Инновейшн Аг Антитела к фно и их функциональные фрагменты
SI3219726T1 (sl) 2016-03-17 2021-02-26 Tillotts Pharma Ag Anti-TNF alfa protitelesa in njihovi funkcionalni fragmenti
US10787508B2 (en) 2016-03-17 2020-09-29 Numab Innovation Ag Anti-TNFα-antibodies and functional fragments thereof
CN118873822A (zh) 2016-12-14 2024-11-01 比奥拉治疗股份有限公司 使用tnf抑制剂治疗胃肠道疾病
CA3055256A1 (en) * 2017-03-09 2018-09-13 Mab Discovery Gmbh Antibodies specifically binding to human il-1r7
EP3810095A1 (en) 2018-06-20 2021-04-28 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a tnf inhibitor
WO2020051275A1 (en) * 2018-09-05 2020-03-12 The Board Of Regents Of The University Of Texas System Monoclonal antibodies against endotrophin and the use thereof
CA3120619A1 (en) 2018-11-19 2020-05-28 Progenity, Inc. Methods and devices for treating a disease with biotherapeutics
WO2020114616A1 (en) 2018-12-07 2020-06-11 Tillotts Pharma Ag Topical treatment of immune checkpoint inhibitor induced diarrhoea, colitis or enterocolitis using antibodies and fragments thereof
WO2021119482A1 (en) 2019-12-13 2021-06-17 Progenity, Inc. Ingestible device for delivery of therapeutic agent to the gastrointestinal tract

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US10787508B2 (en) 2016-03-17 2020-09-29 Numab Innovation Ag Anti-TNFα-antibodies and functional fragments thereof
EA039201B1 (ru) 2016-03-17 2021-12-16 Нумаб Инновейшн Аг Антитела к фно и их функциональные фрагменты

Also Published As

Publication number Publication date
CY1123781T1 (el) 2022-05-27
TW201739765A (zh) 2017-11-16
BR112018067713A2 (pt) 2019-01-08
WO2017158097A1 (en) 2017-09-21
ES2843974T3 (es) 2021-07-21
IL261140B2 (en) 2023-04-01
MA43738A (fr) 2018-11-28
EP3430045B1 (en) 2023-08-23
CA3011786A1 (en) 2017-09-21
SG11202000029PA (en) 2020-02-27
LT3219727T (lt) 2021-02-10
HRP20210120T1 (hr) 2021-03-05
SI3219727T1 (sl) 2021-04-30
EP3219727B1 (en) 2020-12-16
US20200299375A1 (en) 2020-09-24
US10975143B2 (en) 2021-04-13
CN109071651B (zh) 2022-08-30
PL3219727T3 (pl) 2021-05-17
JOP20170063B1 (ar) 2021-08-17
IL261140A (en) 2018-10-31
JP7126485B2 (ja) 2022-08-26
DK3219727T3 (da) 2021-01-04
EA201892097A1 (ru) 2019-02-28
AR107916A1 (es) 2018-06-28
EP3430045A1 (en) 2019-01-23
HUE052869T2 (hu) 2021-05-28
PT3219727T (pt) 2021-01-21
KR20180118671A (ko) 2018-10-31
KR102474765B1 (ko) 2022-12-06
JP2019512269A (ja) 2019-05-16
TWI758280B (zh) 2022-03-21
EP3219727A1 (en) 2017-09-20
IL261140B (en) 2022-12-01
CN109071651A (zh) 2018-12-21
SMT202000703T1 (it) 2021-01-05
UY37158A (es) 2017-10-31

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