PT3219727T - Anticorpos anti-tnf alfa e fragmentos funcionais dos mesmos - Google Patents

Anticorpos anti-tnf alfa e fragmentos funcionais dos mesmos

Info

Publication number: PT3219727T
Authority: PT; Portugal
Prior art keywords: antibodies; functional fragments; tnf alpha; tnf; alpha
Prior art date: 2016-03-17

Application number

PT161609185T

Other languages

English (en)

Original Assignee

Tillotts Pharma Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2016-03-17

Filing date

2016-03-17

Publication date

2021-01-21

2016-03-17 Application filed by Tillotts Pharma Ag filed Critical Tillotts Pharma Ag

2021-01-21 Publication of PT3219727T publication Critical patent/PT3219727T/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/626—Diabody or triabody
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

PT161609185T 2016-03-17 2016-03-17 Anticorpos anti-tnf alfa e fragmentos funcionais dos mesmos PT3219727T (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP16160918.5A EP3219727B1 (en)	2016-03-17	2016-03-17	Anti-tnf alpha-antibodies and functional fragments thereof

Publications (1)

Publication Number	Publication Date
PT3219727T true PT3219727T (pt)	2021-01-21

Family

ID=55542579

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT161609185T PT3219727T (pt)	2016-03-17	2016-03-17	Anticorpos anti-tnf alfa e fragmentos funcionais dos mesmos

Country Status (27)

Country	Link
US (1)	US10975143B2 (pt)
EP (2)	EP3219727B1 (pt)
JP (1)	JP7126485B2 (pt)
KR (1)	KR102474765B1 (pt)
CN (1)	CN109071651B (pt)
AR (1)	AR107916A1 (pt)
BR (1)	BR112018067713A2 (pt)
CA (1)	CA3011786A1 (pt)
CY (1)	CY1123781T1 (pt)
DK (1)	DK3219727T3 (pt)
EA (1)	EA201892097A1 (pt)
ES (1)	ES2843974T3 (pt)
HR (1)	HRP20210120T1 (pt)
HU (1)	HUE052869T2 (pt)
IL (1)	IL261140B2 (pt)
JO (1)	JOP20170063B1 (pt)
LT (1)	LT3219727T (pt)
MA (1)	MA43738A (pt)
PL (1)	PL3219727T3 (pt)
PT (1)	PT3219727T (pt)
RS (1)	RS61412B1 (pt)
SG (1)	SG11202000029PA (pt)
SI (1)	SI3219727T1 (pt)
SM (1)	SMT202000703T1 (pt)
TW (1)	TWI758280B (pt)
UY (1)	UY37158A (pt)
WO (1)	WO2017158097A1 (pt)

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EA039201B1 (ru)	2016-03-17	2021-12-16	Нумаб Инновейшн Аг	Антитела к фно и их функциональные фрагменты
SI3219726T1 (sl)	2016-03-17	2021-02-26	Tillotts Pharma Ag	Anti-TNF alfa protitelesa in njihovi funkcionalni fragmenti
US10787508B2 (en)	2016-03-17	2020-09-29	Numab Innovation Ag	Anti-TNFα-antibodies and functional fragments thereof
CN118873822A (zh)	2016-12-14	2024-11-01	比奥拉治疗股份有限公司	使用tnf抑制剂治疗胃肠道疾病
CA3055256A1 (en) *	2017-03-09	2018-09-13	Mab Discovery Gmbh	Antibodies specifically binding to human il-1r7
EP3810095A1 (en)	2018-06-20	2021-04-28	Progenity, Inc.	Treatment of a disease of the gastrointestinal tract with a tnf inhibitor
WO2020051275A1 (en) *	2018-09-05	2020-03-12	The Board Of Regents Of The University Of Texas System	Monoclonal antibodies against endotrophin and the use thereof
CA3120619A1 (en)	2018-11-19	2020-05-28	Progenity, Inc.	Methods and devices for treating a disease with biotherapeutics
WO2020114616A1 (en)	2018-12-07	2020-06-11	Tillotts Pharma Ag	Topical treatment of immune checkpoint inhibitor induced diarrhoea, colitis or enterocolitis using antibodies and fragments thereof
WO2021119482A1 (en)	2019-12-13	2021-06-17	Progenity, Inc.	Ingestible device for delivery of therapeutic agent to the gastrointestinal tract

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SI3219726T1 (sl)	2016-03-17	2021-02-26	Tillotts Pharma Ag	Anti-TNF alfa protitelesa in njihovi funkcionalni fragmenti
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EA039201B1 (ru)	2016-03-17	2021-12-16	Нумаб Инновейшн Аг	Антитела к фно и их функциональные фрагменты

2016
- 2016-03-17 PT PT161609185T patent/PT3219727T/pt unknown
- 2016-03-17 RS RS20210140A patent/RS61412B1/sr unknown
- 2016-03-17 EP EP16160918.5A patent/EP3219727B1/en active Active
- 2016-03-17 PL PL16160918T patent/PL3219727T3/pl unknown
- 2016-03-17 HU HUE16160918A patent/HUE052869T2/hu unknown
- 2016-03-17 SM SM20200703T patent/SMT202000703T1/it unknown
- 2016-03-17 LT LTEP16160918.5T patent/LT3219727T/lt unknown
- 2016-03-17 ES ES16160918T patent/ES2843974T3/es active Active
- 2016-03-17 DK DK16160918.5T patent/DK3219727T3/da active
- 2016-03-17 SI SI201631041T patent/SI3219727T1/sl unknown
2017
- 2017-03-16 BR BR112018067713A patent/BR112018067713A2/pt unknown
- 2017-03-16 EP EP17712725.5A patent/EP3430045B1/en active Active
- 2017-03-16 MA MA043738A patent/MA43738A/fr unknown
- 2017-03-16 EA EA201892097A patent/EA201892097A1/ru unknown
- 2017-03-16 JP JP2019500014A patent/JP7126485B2/ja active Active
- 2017-03-16 WO PCT/EP2017/056246 patent/WO2017158097A1/en active Application Filing
- 2017-03-16 CA CA3011786A patent/CA3011786A1/en active Pending
- 2017-03-16 JO JOP/2017/0063A patent/JOP20170063B1/ar active
- 2017-03-16 CN CN201780015299.XA patent/CN109071651B/zh active Active
- 2017-03-16 US US16/085,543 patent/US10975143B2/en active Active
- 2017-03-16 KR KR1020187026446A patent/KR102474765B1/ko active Active
- 2017-03-16 SG SG11202000029PA patent/SG11202000029PA/en unknown
- 2017-03-17 UY UY0001037158A patent/UY37158A/es not_active Application Discontinuation
- 2017-03-17 AR ARP170100674A patent/AR107916A1/es unknown
- 2017-03-17 TW TW106108829A patent/TWI758280B/zh active
2018
- 2018-08-13 IL IL261140A patent/IL261140B2/en unknown
2021
- 2021-01-22 HR HRP20210120TT patent/HRP20210120T1/hr unknown
- 2021-01-22 CY CY20211100049T patent/CY1123781T1/el unknown

Also Published As

Publication number	Publication date
CY1123781T1 (el)	2022-05-27
TW201739765A (zh)	2017-11-16
BR112018067713A2 (pt)	2019-01-08
WO2017158097A1 (en)	2017-09-21
ES2843974T3 (es)	2021-07-21
IL261140B2 (en)	2023-04-01
MA43738A (fr)	2018-11-28
EP3430045B1 (en)	2023-08-23
CA3011786A1 (en)	2017-09-21
SG11202000029PA (en)	2020-02-27
LT3219727T (lt)	2021-02-10
HRP20210120T1 (hr)	2021-03-05
SI3219727T1 (sl)	2021-04-30
EP3219727B1 (en)	2020-12-16
US20200299375A1 (en)	2020-09-24
US10975143B2 (en)	2021-04-13
CN109071651B (zh)	2022-08-30
PL3219727T3 (pl)	2021-05-17
JOP20170063B1 (ar)	2021-08-17
IL261140A (en)	2018-10-31
JP7126485B2 (ja)	2022-08-26
DK3219727T3 (da)	2021-01-04
EA201892097A1 (ru)	2019-02-28
AR107916A1 (es)	2018-06-28
EP3430045A1 (en)	2019-01-23
HUE052869T2 (hu)	2021-05-28
RS61412B1 (sr)	2021-03-31
KR20180118671A (ko)	2018-10-31
KR102474765B1 (ko)	2022-12-06
JP2019512269A (ja)	2019-05-16
TWI758280B (zh)	2022-03-21
EP3219727A1 (en)	2017-09-20
IL261140B (en)	2022-12-01
CN109071651A (zh)	2018-12-21
SMT202000703T1 (it)	2021-01-05
UY37158A (es)	2017-10-31

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