RS59493B2 - Kombinacioni tretman raka - Google Patents
Kombinacioni tretman rakaInfo
- Publication number
- RS59493B2 RS59493B2 RS20191392A RSP20191392A RS59493B2 RS 59493 B2 RS59493 B2 RS 59493B2 RS 20191392 A RS20191392 A RS 20191392A RS P20191392 A RSP20191392 A RS P20191392A RS 59493 B2 RS59493 B2 RS 59493B2
- Authority
- RS
- Serbia
- Prior art keywords
- cancer
- combination treatment
- treatment
- combination
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 238000011284 combination treatment Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161564975P | 2011-11-30 | 2011-11-30 | |
PCT/GB2012/052969 WO2013079964A1 (en) | 2011-11-30 | 2012-11-30 | Combination treatment of cancer |
EP12795842.9A EP2785349B2 (en) | 2011-11-30 | 2012-11-30 | Combination treatment of cancer |
Publications (2)
Publication Number | Publication Date |
---|---|
RS59493B1 RS59493B1 (sr) | 2019-12-31 |
RS59493B2 true RS59493B2 (sr) | 2023-02-28 |
Family
ID=47295082
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RS20191392A RS59493B2 (sr) | 2011-11-30 | 2012-11-30 | Kombinacioni tretman raka |
Country Status (27)
Country | Link |
---|---|
US (2) | US20140329786A1 (sr) |
EP (1) | EP2785349B2 (sr) |
JP (1) | JP6309454B2 (sr) |
KR (1) | KR102035361B1 (sr) |
CN (1) | CN103945849B (sr) |
AU (2) | AU2013205648B2 (sr) |
CA (1) | CA2856646C (sr) |
CY (1) | CY1122624T1 (sr) |
DK (1) | DK2785349T4 (sr) |
ES (1) | ES2762250T5 (sr) |
FI (1) | FI2785349T4 (sr) |
HK (1) | HK1202253A1 (sr) |
HR (1) | HRP20191982T4 (sr) |
HU (1) | HUE046667T2 (sr) |
IL (1) | IL232530B (sr) |
LT (1) | LT2785349T (sr) |
MX (1) | MX367640B (sr) |
MY (1) | MY175800A (sr) |
PH (1) | PH12014500943A1 (sr) |
PL (1) | PL2785349T5 (sr) |
PT (1) | PT2785349T (sr) |
RS (1) | RS59493B2 (sr) |
RU (1) | RU2640485C2 (sr) |
SG (1) | SG11201401471PA (sr) |
SI (1) | SI2785349T2 (sr) |
SM (1) | SMT201900708T1 (sr) |
WO (1) | WO2013079964A1 (sr) |
Families Citing this family (23)
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US20100047338A1 (en) | 2008-03-14 | 2010-02-25 | Angela Brodie | Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens, In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity |
ES2770308T3 (es) | 2008-10-02 | 2020-07-01 | Salix Pharmaceuticals Ltd | Procedimientos de tratamiento de encefalopatía hepática |
WO2010091306A1 (en) | 2009-02-05 | 2010-08-12 | Tokai Pharmaceuticals | Novel prodrugs of steroidal cyp17 inhibitors/antiandrogens |
BR112012020558B1 (pt) | 2010-02-16 | 2020-11-03 | Aragon Pharmaceuticals, Inc | moduladores do receptor de androgênio, suas composições farmacêuticas, e seus usos |
WO2012097021A1 (en) | 2011-01-11 | 2012-07-19 | Glaxosmithkline Llc | Combination |
JP2015503508A (ja) * | 2011-12-22 | 2015-02-02 | トーカイ ファーマシューティカルズ,インク. | PI3K/mTOR阻害剤を使用する併用療法のための方法および組成物 |
AU2013204533B2 (en) * | 2012-04-17 | 2017-02-02 | Astrazeneca Ab | Crystalline forms |
EA037806B1 (ru) * | 2012-09-26 | 2021-05-24 | Арагон Фармасьютикалз, Инк. | Способ лечения неметастатического кастрационно-резистентного рака простаты |
JOP20200097A1 (ar) | 2013-01-15 | 2017-06-16 | Aragon Pharmaceuticals Inc | معدل مستقبل أندروجين واستخداماته |
EP4066841A1 (en) | 2013-03-14 | 2022-10-05 | University of Maryland, Baltimore | Androgen receptor down-regulating agents and uses thereof |
SG11201600525XA (en) | 2013-08-12 | 2016-02-26 | Tokai Pharmaceuticals Inc | Biomarkers for treatment of neoplastic disorders using androgen-targeted therapies |
EP3052098B1 (en) * | 2013-10-01 | 2020-12-02 | Novartis AG | Enzalutamide in combination with afuresertib for the treatment of prostate cancer |
BR112016006976A2 (pt) * | 2013-10-01 | 2017-08-01 | Novartis Ag | combinação |
US9566280B2 (en) | 2014-01-28 | 2017-02-14 | Massachusetts Institute Of Technology | Combination therapies and methods of use thereof for treating cancer |
WO2016162229A1 (en) | 2015-04-10 | 2016-10-13 | Capsugel Belgium N.V. | Abiraterone acetate lipid formulations |
TWI726969B (zh) | 2016-01-11 | 2021-05-11 | 比利時商健生藥品公司 | 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物 |
US11478453B2 (en) | 2016-07-21 | 2022-10-25 | Hadasit Medical Research Services And Development Ltd. | Treatment for glioblastoma |
EP3527210B1 (en) | 2016-12-16 | 2021-06-09 | Kangpu Biopharmaceuticals, Ltd. | Combined composition comprising a benzoheterocyclic compound and an androgen receptor pathway modulator and uses thereof |
CN107670048B (zh) * | 2017-08-30 | 2019-04-26 | 南京明臻医药科技有限公司 | 具有协同抗癌活性的中间体药物和聚乙二醇偶联协同抗癌药物、及其制备方法和应用 |
KR20200064993A (ko) * | 2017-09-22 | 2020-06-08 | 디스퍼솔 테크놀로지스, 엘엘씨 | 아비라테론-사이클릭 올리고머 약제학적 제형 및 이의 형성 및 투여 방법 |
SG11202003402QA (en) | 2017-10-16 | 2020-05-28 | Aragon Pharmaceuticals Inc | Anti-androgens for the treatment of non-metastatic castration-resistant prostate cancer |
CN108486041A (zh) * | 2018-03-28 | 2018-09-04 | 华南农业大学 | PI3K/Akt信号通路在鸡胚成纤维细胞内对马立克氏病毒增殖的应用及其检测方法 |
CA3131034A1 (en) | 2019-03-06 | 2020-09-10 | Matthew J. Sharp | Abiraterone prodrugs |
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-
2012
- 2012-11-30 PL PL12795842.9T patent/PL2785349T5/pl unknown
- 2012-11-30 KR KR1020147016680A patent/KR102035361B1/ko active Active
- 2012-11-30 HU HUE12795842A patent/HUE046667T2/hu unknown
- 2012-11-30 PH PH1/2014/500943A patent/PH12014500943A1/en unknown
- 2012-11-30 AU AU2013205648A patent/AU2013205648B2/en active Active
- 2012-11-30 SG SG11201401471PA patent/SG11201401471PA/en unknown
- 2012-11-30 JP JP2014543977A patent/JP6309454B2/ja active Active
- 2012-11-30 AU AU2012321110A patent/AU2012321110B2/en active Active
- 2012-11-30 RU RU2014119713A patent/RU2640485C2/ru active
- 2012-11-30 LT LT12795842T patent/LT2785349T/lt unknown
- 2012-11-30 MY MYPI2014701394A patent/MY175800A/en unknown
- 2012-11-30 WO PCT/GB2012/052969 patent/WO2013079964A1/en active Application Filing
- 2012-11-30 US US14/361,718 patent/US20140329786A1/en not_active Abandoned
- 2012-11-30 MX MX2014006547A patent/MX367640B/es active IP Right Grant
- 2012-11-30 EP EP12795842.9A patent/EP2785349B2/en active Active
- 2012-11-30 RS RS20191392A patent/RS59493B2/sr unknown
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