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RS50937B - Farmaceutska kompozicija koja sadrži metformin i glibenklamid za lečenje šećerne bolesti tipa ii - Google Patents

Farmaceutska kompozicija koja sadrži metformin i glibenklamid za lečenje šećerne bolesti tipa ii

Info

Publication number
RS50937B
RS50937B YUP-473/04A YUP47304A RS50937B RS 50937 B RS50937 B RS 50937B YU P47304 A YUP47304 A YU P47304A RS 50937 B RS50937 B RS 50937B
Authority
RS
Serbia
Prior art keywords
glibenclamide
metformine
treatment
type
pharmaceutical compositions
Prior art date
Application number
YUP-473/04A
Other languages
English (en)
Inventor
Alessandro Tosetti
Mauro Guiducci
Giovanni Viti
Original Assignee
Menarini International Operations Luxembourg S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11442301&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RS50937(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Menarini International Operations Luxembourg S.A. filed Critical Menarini International Operations Luxembourg S.A.
Publication of RS47304A publication Critical patent/RS47304A/sr
Publication of RS50937B publication Critical patent/RS50937B/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Farmaceutska formulacija za oralno davanje u obliku tablete, koja se sastoji od glibenklamida i metformina ili njihovih farmaceutski prihvatljivih soli, kao aktivne materije, naznačena time, što su pomenute aktivne materije u slojevima odvojenim jedan od drugog i količina glibenklamida u svakoj tableti je u opsegu između 1 i 20 mg, a količina metformina u svakoj tableti je u opsegu između 200 i 1000 mg.Prijava sadrži još 17 patentnih zahteva.
YUP-473/04A 2001-11-29 2004-05-28 Farmaceutska kompozicija koja sadrži metformin i glibenklamid za lečenje šećerne bolesti tipa ii RS50937B (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2001FI000230A ITFI20010230A1 (it) 2001-11-29 2001-11-29 Composizioni farmaceutiche per il trattamento del diabete mellito di tipo ii
PCT/EP2002/013497 WO2003045355A1 (en) 2001-11-29 2002-11-29 Pharmaceutical compositions comprising metformine and glibenclamide for the treatment of type-ii diabetes mellitus

Publications (2)

Publication Number Publication Date
RS47304A RS47304A (en) 2006-10-27
RS50937B true RS50937B (sr) 2010-08-31

Family

ID=11442301

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-473/04A RS50937B (sr) 2001-11-29 2004-05-28 Farmaceutska kompozicija koja sadrži metformin i glibenklamid za lečenje šećerne bolesti tipa ii

Country Status (40)

Country Link
US (1) US20050053661A1 (sr)
EP (1) EP1458364B1 (sr)
JP (1) JP4474162B2 (sr)
KR (1) KR20040079898A (sr)
CN (1) CN1596103B (sr)
AR (1) AR037407A1 (sr)
AT (1) ATE387190T1 (sr)
AU (1) AU2002358061B2 (sr)
BR (1) BR0214403A (sr)
CA (1) CA2466677A1 (sr)
CO (1) CO5590906A2 (sr)
CY (1) CY1107966T1 (sr)
DE (1) DE60225331T2 (sr)
DK (1) DK1458364T3 (sr)
EA (1) EA006766B1 (sr)
EG (1) EG24124A (sr)
ES (1) ES2302862T3 (sr)
HK (1) HK1069974A1 (sr)
HN (1) HN2002000341A (sr)
HR (1) HRP20040501A2 (sr)
HU (1) HUP0402154A3 (sr)
IL (1) IL162143A0 (sr)
IT (1) ITFI20010230A1 (sr)
MA (1) MA27087A1 (sr)
MX (1) MXPA04004974A (sr)
MY (1) MY141243A (sr)
NO (1) NO20042713L (sr)
NZ (1) NZ533779A (sr)
PA (1) PA8559801A1 (sr)
PE (1) PE20030580A1 (sr)
PL (1) PL206016B1 (sr)
PT (1) PT1458364E (sr)
RS (1) RS50937B (sr)
SI (1) SI1458364T1 (sr)
SV (1) SV2004001415A (sr)
TN (1) TNSN04095A1 (sr)
UA (1) UA81615C2 (sr)
UY (1) UY27549A1 (sr)
WO (1) WO2003045355A1 (sr)
ZA (1) ZA200404880B (sr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
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MXPA03006217A (es) * 2001-01-12 2004-10-15 Sun Pharmaceutical Ind Ltd Sistema de administracion espaciada de farmacos.
EP1515701B1 (en) 2002-06-17 2014-09-17 Inventia Healthcare Private Limited Process for the manufacture of multilayer tablet compositions comprising thiazolidinedione and biguanide
US7785627B2 (en) 2002-09-20 2010-08-31 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US9060941B2 (en) 2002-09-20 2015-06-23 Actavis, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
EP2316456B1 (en) 2003-04-29 2017-06-14 Orexigen Therapeutics, Inc. Compositions for affecting weight loss comprising an opioid antagonist and bupropion
PE20061245A1 (es) * 2005-03-30 2007-01-06 Generex Pharm Inc Composiciones para la transmision transmucosa oral de la metformina
TWI471145B (zh) * 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
KR101479324B1 (ko) * 2006-11-09 2015-01-05 오렉시젠 세러퓨틱스 인크. 신속하게 용해되는 중간층을 포함하는 층상의 약제학적 제형
ITMI20062254A1 (it) * 2006-11-24 2008-05-25 Acraf Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca
EP2303025A4 (en) 2008-05-30 2012-07-04 Orexigen Therapeutics Inc METHOD FOR TREATING DIGITAL FAT SWITCHES
CA2638240C (en) 2008-08-29 2010-02-02 Alexander Macgregor Method of treating dysglycemia and glucose excursions
US9248123B2 (en) 2010-01-11 2016-02-02 Orexigen Therapeutics, Inc. Methods of providing weight loss therapy in patients with major depression
RU2483717C2 (ru) * 2010-11-22 2013-06-10 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Фармацевтическая композиция для лечения диабета (варианты)
US8796338B2 (en) 2011-01-07 2014-08-05 Elcelyx Therapeutics, Inc Biguanide compositions and methods of treating metabolic disorders
US9211263B2 (en) 2012-01-06 2015-12-15 Elcelyx Therapeutics, Inc. Compositions and methods of treating metabolic disorders
US9572784B2 (en) 2011-01-07 2017-02-21 Elcelyx Therapeutics, Inc. Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk
US11759441B2 (en) 2011-01-07 2023-09-19 Anji Pharmaceuticals Inc. Biguanide compositions and methods of treating metabolic disorders
US11974971B2 (en) 2011-01-07 2024-05-07 Anji Pharmaceuticals Inc. Compositions and methods for treating metabolic disorders
US9480663B2 (en) 2011-01-07 2016-11-01 Elcelyx Therapeutics, Inc. Biguanide compositions and methods of treating metabolic disorders
SG10201607085WA (en) 2011-01-07 2016-10-28 Elcelyx Therapeutics Inc Chemosensory Receptor Ligand-Based Therapies
EP2800562A2 (en) 2012-01-06 2014-11-12 Elcelyx Therapeutics, Inc. Compositions and methods for treating metabolic disorders
EP2800561B1 (en) 2012-01-06 2020-08-19 Anji Pharma (US) LLC Biguanide compositions and methods of treating metabolic disorders
KR20200035501A (ko) 2012-06-06 2020-04-03 오렉시젠 세러퓨틱스 인크. 과체중 및 비만의 치료 방법
EP3219318A4 (en) 2014-11-11 2018-07-11 Shionogi & Co., Ltd. Multi-layered tablet containing drug unstable with respect to light
KR101750690B1 (ko) * 2015-10-28 2017-06-27 주식회사 종근당 메트포르민 및 로베글리타존을 포함하는 약제학적 조성물
CN105596339A (zh) * 2015-12-23 2016-05-25 青岛海之源智能技术有限公司 一种二甲双胍阿昔莫司复方组合物及制备方法
CN110128305A (zh) * 2019-05-10 2019-08-16 天津大学 二甲双胍-甲苯磺丁脲新盐型、其制备方法及医药用途
JP2021120357A (ja) * 2020-01-30 2021-08-19 サンノーバ株式会社 錠剤
GB2599950A (en) * 2020-10-16 2022-04-20 Zentiva Ks Pharmaceutical compositions with low amounts of nitrosamine impurities and methods for producing the same
CN113143940A (zh) * 2020-12-30 2021-07-23 成都恒瑞制药有限公司 一种抗糖尿病药物组合物的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2347531A1 (de) * 1973-09-21 1975-04-30 Hoechst Ag Arzneizubereitungen zur oralen diabetes-behandlung
IT1276130B1 (it) * 1995-11-14 1997-10-27 Gentili Ist Spa Associazione glibenclamide-metformina, composizioni farmaceutiche che la contengono e loro uso nel trattamento del diabete mellito di tipo
EP2332522A3 (en) * 1998-03-19 2011-12-07 Bristol-Myers Squibb Company Biphasic controlled release delivery system for high solubility pharmaceuticals and method
SI0974356T1 (en) * 1998-07-15 2003-12-31 Merck Sante Tablets comprising a combination of metformin and glibenclamide
US6780432B1 (en) * 2000-05-01 2004-08-24 Aeropharm Technology, Inc. Core formulation
MXPA03006217A (es) * 2001-01-12 2004-10-15 Sun Pharmaceutical Ind Ltd Sistema de administracion espaciada de farmacos.

Also Published As

Publication number Publication date
ITFI20010230A1 (it) 2003-05-29
PA8559801A1 (es) 2003-06-30
HRP20040501A2 (en) 2004-12-31
EP1458364B1 (en) 2008-02-27
CY1107966T1 (el) 2013-09-04
CN1596103A (zh) 2005-03-16
HUP0402154A3 (en) 2008-04-28
JP2005518360A (ja) 2005-06-23
MA27087A1 (fr) 2004-12-20
CA2466677A1 (en) 2003-06-05
AU2002358061B2 (en) 2007-01-11
TNSN04095A1 (en) 2006-06-01
JP4474162B2 (ja) 2010-06-02
PL369851A1 (en) 2005-05-02
HUP0402154A2 (hu) 2005-02-28
ZA200404880B (en) 2005-07-29
US20050053661A1 (en) 2005-03-10
PT1458364E (pt) 2008-05-26
NZ533779A (en) 2007-02-23
EA006766B1 (ru) 2006-04-28
PE20030580A1 (es) 2003-09-05
SV2004001415A (es) 2004-05-07
CN1596103B (zh) 2010-06-16
EG24124A (en) 2008-07-07
UA81615C2 (ru) 2008-01-25
NO20042713L (no) 2004-07-16
ATE387190T1 (de) 2008-03-15
RS47304A (en) 2006-10-27
MXPA04004974A (es) 2004-08-11
CO5590906A2 (es) 2005-12-30
UY27549A1 (es) 2003-06-30
PL206016B1 (pl) 2010-06-30
DK1458364T3 (da) 2008-06-23
AR037407A1 (es) 2004-11-10
WO2003045355A1 (en) 2003-06-05
SI1458364T1 (sl) 2008-08-31
AU2002358061A1 (en) 2003-06-10
MY141243A (en) 2010-03-31
HK1069974A1 (en) 2005-06-10
BR0214403A (pt) 2004-10-19
KR20040079898A (ko) 2004-09-16
DE60225331T2 (de) 2009-02-26
EA200400664A1 (ru) 2004-10-28
HN2002000341A (es) 2009-12-07
EP1458364A1 (en) 2004-09-22
DE60225331D1 (de) 2008-04-10
ES2302862T3 (es) 2008-08-01
IL162143A0 (en) 2005-11-20

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