RS49702B - Stereoselektivna mikrobska redukcija racemskog tetralona - Google Patents
Stereoselektivna mikrobska redukcija racemskog tetralonaInfo
- Publication number
- RS49702B RS49702B YUP-551/99A YU55199A RS49702B RS 49702 B RS49702 B RS 49702B YU 55199 A YU55199 A YU 55199A RS 49702 B RS49702 B RS 49702B
- Authority
- RS
- Serbia
- Prior art keywords
- atcc
- formula
- compound
- microorganism
- reduction
- Prior art date
Links
- 230000000813 microbial effect Effects 0.000 title abstract 2
- 230000000707 stereoselective effect Effects 0.000 title abstract 2
- XHLHPRDBBAGVEG-UHFFFAOYSA-N 1-tetralone Chemical compound C1=CC=C2C(=O)CCCC2=C1 XHLHPRDBBAGVEG-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 7
- 102000004190 Enzymes Human genes 0.000 abstract 3
- 108090000790 Enzymes Proteins 0.000 abstract 3
- 244000005700 microbiome Species 0.000 abstract 3
- 241000320412 Ogataea angusta Species 0.000 abstract 2
- 241000306282 Umbelopsis isabellina Species 0.000 abstract 2
- 241000293029 Absidia caerulea Species 0.000 abstract 1
- 241000223678 Aureobasidium pullulans Species 0.000 abstract 1
- 241001489166 Cyberlindnera fabianii Species 0.000 abstract 1
- 244000168141 Geotrichum candidum Species 0.000 abstract 1
- 235000017388 Geotrichum candidum Nutrition 0.000 abstract 1
- 241001539803 Magnusiomyces capitatus Species 0.000 abstract 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 abstract 1
- 241001123649 Schwanniomyces polymorphus Species 0.000 abstract 1
- 241000187419 Streptomyces rimosus Species 0.000 abstract 1
- 241000180122 Umbelopsis vinacea Species 0.000 abstract 1
- 241000863486 Vinca minor Species 0.000 abstract 1
- 241000192237 [Candida] schatavii Species 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
- C12P7/26—Ketones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Postupak stereoselektivne mikrobske redukcije jedinjenja formule (I) do jedinjenja formula (II) i (III) koji obuhvata: dovodjenje u kontakt jedinjenja formule (I) sa mikroorganizmom, ili enzimskim redukcionim sistemom koji može da izvrši redukovanje, a koji sadrži jedan enzim izveden iz datog mikroorganizma i jedan ko-faktor za dati enzim, i inkubaciju dobijene mešavine pod uslovima dovoljnim da se dobije više jedinjenja formule (II) nego jedinjenja formule (III), ostavljajući više neizreagovanog jedinjenja formule (V) nego jedinjenja formule (IV), pri čemu se mikroorganizam bira iz sledeće grupe: Hansenula polymorpha ATCC No. 26012, Hansenula polymorpha ATCC No. 74449, Absidia coerulea ATCC No. 20317, Geotrichum candidum ATCC No. 34614, Geotrichum candidum ATCC No.62401, Mortierella isabellina ATCC No.42613, Mortierella isabellina ATCC No. 38063, Mortierella vinacea ATCC No.09515, Penicillum notatum ATCC No.36740, Blastoschizomyces capitatus ATCC No.28575, Monosporium olivaceuom v. major ATCC No.36300, Aureobasidium pullulans ATCC No. 16623, Debaryomyces polymorphus ATCC No.20280, Saccharomyces cerevisiae ATCC No.15248, Candida schatavii ATCC No.24409, Pichia fabianii ATCC No.16755 i Streptomyces rimosus ss. rimosus ATCC No.10970, i njihovi mutanti koji mogu da ostvare ovu reakciju.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10623398P | 1998-10-29 | 1998-10-29 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| YU55199A YU55199A (sh) | 2003-04-30 |
| RS49702B true RS49702B (sr) | 2007-12-31 |
Family
ID=22310267
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YUP-551/99A RS49702B (sr) | 1998-10-29 | 1999-10-27 | Stereoselektivna mikrobska redukcija racemskog tetralona |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US6589777B1 (sr) |
| EP (1) | EP0997535B1 (sr) |
| JP (2) | JP3106135B2 (sr) |
| KR (2) | KR100432309B1 (sr) |
| CN (1) | CN1252277C (sr) |
| AR (1) | AR018967A1 (sr) |
| AT (1) | ATE328107T1 (sr) |
| AU (1) | AU751282B2 (sr) |
| BR (1) | BR9904964A (sr) |
| CA (1) | CA2287560C (sr) |
| CY (1) | CY1105148T1 (sr) |
| CZ (1) | CZ293579B6 (sr) |
| DE (1) | DE69931574T2 (sr) |
| DK (1) | DK0997535T3 (sr) |
| ES (1) | ES2264244T3 (sr) |
| HK (1) | HK1027596A1 (sr) |
| HU (1) | HUP9903941A3 (sr) |
| ID (1) | ID23591A (sr) |
| IL (1) | IL132500A0 (sr) |
| IN (1) | IN191494B (sr) |
| PL (1) | PL336331A1 (sr) |
| PT (1) | PT997535E (sr) |
| RS (1) | RS49702B (sr) |
| RU (1) | RU2235784C2 (sr) |
| TR (1) | TR199902668A2 (sr) |
| TW (1) | TWI224141B (sr) |
| ZA (1) | ZA996786B (sr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN187170B (sr) * | 2000-01-04 | 2002-02-23 | Sun Pharmaceutical Ind Ltd | |
| EP1457570A4 (en) * | 2001-11-28 | 2006-02-01 | Kaneka Corp | PROCESS FOR THE PREPARATION OF 2-AMINOTETRALIN DERIVATIVES AND THEIR INTERMEDIATE COMPOUNDS |
| WO2015071861A2 (en) * | 2013-11-14 | 2015-05-21 | Biocon Limited | Fungus mediated stereo-selective bioreduction of keto intermediates of pharmaceutically active compounds to their corresponding hydroxy compounds |
| CN104293856A (zh) * | 2014-10-30 | 2015-01-21 | 青岛科技大学 | 一种细胞催化生产氟吡啶乙酮的方法 |
| CN107418981B (zh) * | 2017-06-27 | 2020-04-07 | 中山大学 | 白地霉菌株不对称催化还原卤代芳香酮的方法 |
| CN107746861B (zh) * | 2017-11-20 | 2020-06-23 | 浙江工业大学 | 一种(r)-1-(2-三氟甲基苯基)乙醇的生物制备方法 |
| KR102319188B1 (ko) * | 2019-06-04 | 2021-10-29 | (주)이엔씨파워 | 횡단보도용 양면 표지판 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4536518A (en) | 1979-11-01 | 1985-08-20 | Pfizer Inc. | Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine |
| US4857468A (en) * | 1985-04-13 | 1989-08-15 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Process for preparing optically active 2-halo-1-phenyl ethanol |
| US5049497A (en) | 1986-08-25 | 1991-09-17 | Syntex (U.S.A.) Inc. | Novel process for the synthesis of the enantiomers of bicyclo(4.2.0)oct-2-en-7-one and derivatives |
| US4839104A (en) | 1987-06-11 | 1989-06-13 | Pfizer, Inc. | Process for preparing sertraline intermediates |
| US4777288A (en) | 1987-06-11 | 1988-10-11 | Pfizer Inc. | Process for preparing a 4,4-diphenylbutanoic acid derivative |
| US4855500A (en) | 1988-05-04 | 1989-08-08 | Pfizer Inc. | Process for preparing a ketimine |
| US5130338A (en) | 1989-08-30 | 1992-07-14 | Pfizer Inc. | Method of treating chemical dependencies using sertraline |
| US4940731A (en) | 1989-08-30 | 1990-07-10 | Pfizer Inc. | Method of treating premature ejaculation using sertraline |
| US4962128A (en) | 1989-11-02 | 1990-10-09 | Pfizer Inc. | Method of treating anxiety-related disorders using sertraline |
| US5082970A (en) | 1991-03-06 | 1992-01-21 | Pfizer Inc. | Process for recycling amine isomer |
| GB9114948D0 (en) | 1991-07-11 | 1991-08-28 | Pfizer Ltd | Process for preparing sertraline intermediates |
| GB9114947D0 (en) | 1991-07-11 | 1991-08-28 | Pfizer Ltd | Process for preparing sertraline |
| US5196607A (en) | 1992-02-14 | 1993-03-23 | Pfizer Inc. | Process for preparing ketone enantiomer |
| DK0630402T3 (da) | 1992-03-13 | 1997-12-22 | Forschungszentrum Juelich Gmbh | Ny ketoesterreduktase, fremstilling deraf og anvendelse deraf til enzymatiske redoxreaktioner |
| US5248699A (en) | 1992-08-13 | 1993-09-28 | Pfizer Inc. | Sertraline polymorph |
| WO1994005802A1 (en) | 1992-08-28 | 1994-03-17 | Zeneca Limited | Enzymatic asymmetric reduction process to produce 4 h-thieno(2,3-6)thio pyrane derivatives |
| US5466880A (en) | 1992-09-15 | 1995-11-14 | Pfizer Inc. | Process for preparing ketone enantiomer |
| DE69406553T2 (de) * | 1993-11-30 | 1998-02-26 | Pfizer Inc., New York, N.Y. | Verfahren zur herstellung von chiralen tetralonen |
| US5597826A (en) | 1994-09-14 | 1997-01-28 | Pfizer Inc. | Compositions containing sertraline and a 5-HT1D receptor agonist or antagonist |
| US5618707A (en) | 1996-01-04 | 1997-04-08 | Schering Corporation | Stereoselective microbial reduction of 5-fluorophenyl-5-oxo-pentanoic acid and a phenyloxazolidinone condensation product thereof |
-
1999
- 1999-10-21 IL IL13250099A patent/IL132500A0/xx not_active IP Right Cessation
- 1999-10-22 IN IN1409DE1999 patent/IN191494B/en unknown
- 1999-10-25 DK DK99308422T patent/DK0997535T3/da active
- 1999-10-25 CZ CZ19993790A patent/CZ293579B6/cs not_active IP Right Cessation
- 1999-10-25 PT PT99308422T patent/PT997535E/pt unknown
- 1999-10-25 TW TW088118421A patent/TWI224141B/zh not_active IP Right Cessation
- 1999-10-25 AT AT99308422T patent/ATE328107T1/de not_active IP Right Cessation
- 1999-10-25 EP EP99308422A patent/EP0997535B1/en not_active Expired - Lifetime
- 1999-10-25 DE DE69931574T patent/DE69931574T2/de not_active Expired - Fee Related
- 1999-10-25 ES ES99308422T patent/ES2264244T3/es not_active Expired - Lifetime
- 1999-10-26 TR TR1999/02668A patent/TR199902668A2/xx unknown
- 1999-10-26 US US09/427,424 patent/US6589777B1/en not_active Expired - Fee Related
- 1999-10-27 CA CA002287560A patent/CA2287560C/en not_active Expired - Fee Related
- 1999-10-27 AR ARP990105423A patent/AR018967A1/es active IP Right Grant
- 1999-10-27 RS YUP-551/99A patent/RS49702B/sr unknown
- 1999-10-27 ID IDP990987D patent/ID23591A/id unknown
- 1999-10-28 KR KR10-1999-0047145A patent/KR100432309B1/ko not_active IP Right Cessation
- 1999-10-28 CN CNB991233883A patent/CN1252277C/zh not_active Expired - Fee Related
- 1999-10-28 ZA ZA9906786A patent/ZA996786B/xx unknown
- 1999-10-28 BR BR9904964-3A patent/BR9904964A/pt not_active Application Discontinuation
- 1999-10-28 AU AU57097/99A patent/AU751282B2/en not_active Ceased
- 1999-10-28 RU RU99122704/13A patent/RU2235784C2/ru not_active IP Right Cessation
- 1999-10-28 JP JP11307272A patent/JP3106135B2/ja not_active Expired - Fee Related
- 1999-10-28 PL PL99336331A patent/PL336331A1/xx not_active IP Right Cessation
- 1999-10-28 HU HU9903941A patent/HUP9903941A3/hu unknown
-
2000
- 2000-06-30 JP JP2000198150A patent/JP3359905B2/ja not_active Expired - Fee Related
- 2000-10-23 HK HK00106703A patent/HK1027596A1/xx not_active IP Right Cessation
-
2003
- 2003-08-20 KR KR10-2003-0057440A patent/KR100432306B1/ko not_active IP Right Cessation
-
2006
- 2006-08-10 CY CY20061101126T patent/CY1105148T1/el unknown
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