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PT99435A - Processo para a preparacao de derivados de amino-sulfonil-ureia e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de derivados de amino-sulfonil-ureia e de composicoes farmaceuticas que os contem

Info

Publication number
PT99435A
PT99435A PT99435A PT9943591A PT99435A PT 99435 A PT99435 A PT 99435A PT 99435 A PT99435 A PT 99435A PT 9943591 A PT9943591 A PT 9943591A PT 99435 A PT99435 A PT 99435A
Authority
PT
Portugal
Prior art keywords
pharmaceutical compositions
sulfonyl
amino
preparation
compositions containing
Prior art date
Application number
PT99435A
Other languages
English (en)
Other versions
PT99435B (pt
Inventor
Drago Robert Sliskovic
Joseph Armand Picard
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of PT99435A publication Critical patent/PT99435A/pt
Publication of PT99435B publication Critical patent/PT99435B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/96—Sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C307/04—Diamides of sulfuric acids
    • C07C307/06—Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C307/04—Diamides of sulfuric acids
    • C07C307/08—Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C307/04—Diamides of sulfuric acids
    • C07C307/10—Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/14—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT99435A 1990-11-07 1991-11-06 Processo para a preparacao de derivados de amino-sulfonil-ureia e de composicoes farmaceuticas que os contem PT99435B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61028790A 1990-11-07 1990-11-07
US07/747,040 US5214206A (en) 1990-11-07 1991-08-19 Aminosulfonyl urea acat inhibitors

Publications (2)

Publication Number Publication Date
PT99435A true PT99435A (pt) 1992-12-31
PT99435B PT99435B (pt) 1999-04-30

Family

ID=27086230

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99435A PT99435B (pt) 1990-11-07 1991-11-06 Processo para a preparacao de derivados de amino-sulfonil-ureia e de composicoes farmaceuticas que os contem

Country Status (16)

Country Link
US (2) US5214206A (pt)
EP (1) EP0556322B1 (pt)
JP (2) JP3256541B2 (pt)
AT (1) ATE139226T1 (pt)
AU (1) AU657928B2 (pt)
CA (1) CA2094806C (pt)
DE (1) DE69120287T2 (pt)
DK (1) DK0556322T3 (pt)
ES (1) ES2088128T3 (pt)
GR (1) GR3020355T3 (pt)
IE (1) IE75379B1 (pt)
MX (1) MX9101958A (pt)
NZ (1) NZ240481A (pt)
PH (1) PH30665A (pt)
PT (1) PT99435B (pt)
WO (1) WO1992008694A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT68721A (en) * 1990-12-28 1995-07-28 Teijin Ltd Benzofuran and benzizoxazole derivatives, pharmaceutical composition containing said compounds as active agent and process for preparing them
US5576335A (en) * 1994-02-01 1996-11-19 Nisshin Flour Milling Co., Ltd. Urea derivatives and their use as ACAT inhibitors
US5491170A (en) * 1994-12-19 1996-02-13 Warner-Lambert Company β-carboxy sulfonamide ACAT inhibitors
US6103733A (en) * 1998-09-09 2000-08-15 Bachmann; Kenneth A. Method for increasing HDL cholesterol levels using heteroaromatic phenylmethanes
CA2369967A1 (en) * 2001-02-12 2002-08-12 Joseph Anthony Cornicelli Methods of treating nuclear factor-kappa b mediated diseases and disorders
EP1281399A3 (en) * 2001-08-01 2004-02-11 Warner-Lambert Company Dual inhibitors of wax ester and cholesteryl ester synthesis for inhibiting sebum production
DK2881392T3 (en) * 2010-11-16 2018-07-23 Texas Heart Inst Agonists that enhance the binding of integrin-expressing cells to integrin receptors
CN103288749A (zh) * 2013-03-04 2013-09-11 盐城工学院 可作除草剂的氨基磺酰脲类化合物
CN112494657B (zh) * 2014-10-03 2025-02-11 西纳福克斯股份有限公司 磺酰胺接头、其缀合物及制备方法
RS62164B1 (sr) 2015-02-16 2021-08-31 Univ Queensland Sulfoniluree i srodna jedinjenja i njihova upotreba
CA3014487A1 (en) * 2016-02-16 2017-08-24 The Provost, Fellows, Foundation Scholars, And The Other Members Of Board, Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin Sulfonylureas and related compounds and use of same
KR102669722B1 (ko) 2017-07-07 2024-05-29 인플라좀 리미티드 신규한 설폰아마이드 카복스아마이드 화합물
GB201721185D0 (en) 2017-12-18 2018-01-31 Nodthera Ltd Sulphonyl urea derivatives
MA53221A (fr) * 2018-08-15 2022-04-27 Inflazome Ltd Nouveaux composés de sulfonamide urée
PT3983387T (pt) 2019-06-12 2024-07-10 Nodthera Ltd Derivados de sulfonilurea e seus usos

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2312404A (en) * 1939-11-22 1943-03-02 Haack Erich Method of preparing n-sulphonylureas
CH396872A (de) * 1959-08-13 1965-08-15 Ciba Geigy Verfahren zur Herstellung neuer Harnstoffe
US3242174A (en) * 1962-02-06 1966-03-22 Pfizer & Co C 1-(tertiary aminosulfonyl)-3-(hydrocarbon) ureas
GB990860A (en) * 1962-02-08 1965-05-05 Pfizer & Co C N,n-disubstituted sulfamylureas and compositions thereof
US3245982A (en) * 1962-03-27 1966-04-12 Pfizer & Co C Sulfamylsemicarbazides
DE1518541A1 (de) * 1965-03-16 1969-09-11 Boehringer Mannheim Gmbh Verfahren zur Herstellung von Sulfonylharnstoffen und Sulfonylsemicarbaziden
CH649081A5 (de) * 1982-01-12 1985-04-30 Ciba Geigy Ag Triaza-verbindungen.

Also Published As

Publication number Publication date
AU657928B2 (en) 1995-03-30
ES2088128T3 (es) 1996-08-01
IE75379B1 (en) 1997-09-10
PH30665A (en) 1997-09-16
US5288757A (en) 1994-02-22
IE913874A1 (en) 1992-05-20
JPH06501707A (ja) 1994-02-24
GR3020355T3 (en) 1996-09-30
CA2094806C (en) 2004-11-02
DE69120287T2 (de) 1996-10-10
JP3256541B2 (ja) 2002-02-12
CA2094806A1 (en) 1992-05-08
PT99435B (pt) 1999-04-30
NZ240481A (en) 1994-06-27
WO1992008694A1 (en) 1992-05-29
MX9101958A (es) 1992-07-08
ATE139226T1 (de) 1996-06-15
JP2001026574A (ja) 2001-01-30
EP0556322B1 (en) 1996-06-12
AU8959791A (en) 1992-06-11
US5214206A (en) 1993-05-25
DK0556322T3 (da) 1996-10-14
EP0556322A1 (en) 1993-08-25
DE69120287D1 (en) 1996-07-18

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19920814

FG3A Patent granted, date of granting

Effective date: 19990119

MM3A Annulment or lapse

Effective date: 20060719