DK0556322T3 - Aminosulfonylurinstof-ACAT-inhibitorer - Google Patents

Aminosulfonylurinstof-ACAT-inhibitorer

Info

Publication number: DK0556322T3
Authority: DK; Denmark
Prior art keywords: acat inhibitors; compounds; aminosulfonylurinstof; useful; aminosulfonyl
Prior art date: 1990-11-07

Application number

DK92900981.9T

Other languages

English (en)

Inventor

Joseph Armand Picard

Drago Robert Sliskovic

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-11-07

Filing date

1991-11-05

Publication date

1996-10-14

1991-11-05 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

1996-10-14 Application granted granted Critical

1996-10-14 Publication of DK0556322T3 publication Critical patent/DK0556322T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/96—Sulfur atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C307/04—Diamides of sulfuric acids
- C07C307/06—Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C307/04—Diamides of sulfuric acids
- C07C307/08—Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C307/04—Diamides of sulfuric acids
- C07C307/10—Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to carbon atoms of six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/14—Radicals substituted by nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Urology & Nephrology (AREA)
Obesity (AREA)
Diabetes (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Furan Compounds (AREA)
Hydrogenated Pyridines (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK92900981.9T 1990-11-07 1991-11-05 Aminosulfonylurinstof-ACAT-inhibitorer DK0556322T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US61028790A	1990-11-07	1990-11-07
US07/747,040 US5214206A (en)	1990-11-07	1991-08-19	Aminosulfonyl urea acat inhibitors

Publications (1)

Publication Number	Publication Date
DK0556322T3 true DK0556322T3 (da)	1996-10-14

Family

ID=27086230

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK92900981.9T DK0556322T3 (da)	1990-11-07	1991-11-05	Aminosulfonylurinstof-ACAT-inhibitorer

Country Status (16)

Country	Link
US (2)	US5214206A (da)
EP (1)	EP0556322B1 (da)
JP (2)	JP3256541B2 (da)
AT (1)	ATE139226T1 (da)
AU (1)	AU657928B2 (da)
CA (1)	CA2094806C (da)
DE (1)	DE69120287T2 (da)
DK (1)	DK0556322T3 (da)
ES (1)	ES2088128T3 (da)
GR (1)	GR3020355T3 (da)
IE (1)	IE75379B1 (da)
MX (1)	MX9101958A (da)
NZ (1)	NZ240481A (da)
PH (1)	PH30665A (da)
PT (1)	PT99435B (da)
WO (1)	WO1992008694A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE192446T1 (de) *	1990-12-28	2000-05-15	Teijin Ltd	Kondensierte benzoxa-ringverbindung, deren herstellung sowie diese enthaltendes arzneimittel
US5576335A (en) *	1994-02-01	1996-11-19	Nisshin Flour Milling Co., Ltd.	Urea derivatives and their use as ACAT inhibitors
US5491170A (en) *	1994-12-19	1996-02-13	Warner-Lambert Company	β-carboxy sulfonamide ACAT inhibitors
US6103733A (en) *	1998-09-09	2000-08-15	Bachmann; Kenneth A.	Method for increasing HDL cholesterol levels using heteroaromatic phenylmethanes
CA2369967A1 (en) *	2001-02-12	2002-08-12	Joseph Anthony Cornicelli	Methods of treating nuclear factor-kappa b mediated diseases and disorders
EP1281399A3 (en) *	2001-08-01	2004-02-11	Warner-Lambert Company	Dual inhibitors of wax ester and cholesteryl ester synthesis for inhibiting sebum production
EP2881392B1 (en) *	2010-11-16	2018-06-06	Texas Heart Institute	Agonists that enhance binding of integrin-expressing cells to integrin receptors
CN103288749A (zh) *	2013-03-04	2013-09-11	盐城工学院	可作除草剂的氨基磺酰脲类化合物
EP3733209A1 (en) *	2014-10-03	2020-11-04	Synaffix B.V.	Sulfamide linker, conjugates thereof, and methods of preparation
SI3578547T1 (sl) *	2015-02-16	2021-09-30	The University Of Queensland	Sulfonilsečnine in sorodne spojine ter njihova uporaba
WO2017140778A1 (en) *	2016-02-16	2017-08-24	The University Of Queensland	Sulfonylureas and related compounds and use of same
CA3067410A1 (en)	2017-07-07	2019-01-10	Inflazome Limited	Novel sulfonamide carboxamide compounds
GB201721185D0 (en)	2017-12-18	2018-01-31	Nodthera Ltd	Sulphonyl urea derivatives
SG11202101480XA (en) *	2018-08-15	2021-03-30	Inflazome Ltd	Novel sulfonamideurea compounds
PL3983387T3 (pl)	2019-06-12	2024-08-19	NodThera Limited	Pochodne sulfonylomocznika i ich zastosowania

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2312404A (en) *	1939-11-22	1943-03-02	Haack Erich	Method of preparing n-sulphonylureas
CH396872A (de)	1959-08-13	1965-08-15	Ciba Geigy	Verfahren zur Herstellung neuer Harnstoffe
US3242174A (en) *	1962-02-06	1966-03-22	Pfizer & Co C	1-(tertiary aminosulfonyl)-3-(hydrocarbon) ureas
GB990860A (en) *	1962-02-08	1965-05-05	Pfizer & Co C	N,n-disubstituted sulfamylureas and compositions thereof
US3245982A (en) *	1962-03-27	1966-04-12	Pfizer & Co C	Sulfamylsemicarbazides
DE1518541A1 (de) *	1965-03-16	1969-09-11	Boehringer Mannheim Gmbh	Verfahren zur Herstellung von Sulfonylharnstoffen und Sulfonylsemicarbaziden
FR2339694A1 (fr)	1976-01-30	1977-08-26	Martin Usines Fonderie Arthur	Machine a laver le linge comportant un dispositif de sechage par ventilation d'air chaud
CH649081A5 (de) *	1982-01-12	1985-04-30	Ciba Geigy Ag	Triaza-verbindungen.

1991
- 1991-08-19 US US07/747,040 patent/US5214206A/en not_active Expired - Lifetime
- 1991-11-05 AT AT92900981T patent/ATE139226T1/de not_active IP Right Cessation
- 1991-11-05 WO PCT/US1991/008223 patent/WO1992008694A1/en not_active Ceased
- 1991-11-05 DE DE69120287T patent/DE69120287T2/de not_active Expired - Fee Related
- 1991-11-05 NZ NZ240481A patent/NZ240481A/xx not_active IP Right Cessation
- 1991-11-05 DK DK92900981.9T patent/DK0556322T3/da active
- 1991-11-05 AU AU89597/91A patent/AU657928B2/en not_active Ceased
- 1991-11-05 JP JP50093292A patent/JP3256541B2/ja not_active Expired - Fee Related
- 1991-11-05 ES ES92900981T patent/ES2088128T3/es not_active Expired - Lifetime
- 1991-11-05 EP EP92900981A patent/EP0556322B1/en not_active Expired - Lifetime
- 1991-11-05 CA CA002094806A patent/CA2094806C/en not_active Expired - Fee Related
- 1991-11-06 PT PT99435A patent/PT99435B/pt not_active IP Right Cessation
- 1991-11-06 IE IE387491A patent/IE75379B1/en not_active IP Right Cessation
- 1991-11-06 MX MX9101958A patent/MX9101958A/es not_active IP Right Cessation
- 1991-11-06 PH PH43413A patent/PH30665A/en unknown
1993
- 1993-02-19 US US08/019,519 patent/US5288757A/en not_active Expired - Lifetime
1996
- 1996-06-27 GR GR960401724T patent/GR3020355T3/el unknown
2000
- 2000-06-14 JP JP2000177740A patent/JP2001026574A/ja active Pending

Also Published As

Publication number	Publication date
EP0556322A1 (en)	1993-08-25
EP0556322B1 (en)	1996-06-12
IE75379B1 (en)	1997-09-10
WO1992008694A1 (en)	1992-05-29
ATE139226T1 (de)	1996-06-15
ES2088128T3 (es)	1996-08-01
JP3256541B2 (ja)	2002-02-12
CA2094806A1 (en)	1992-05-08
JPH06501707A (ja)	1994-02-24
PT99435A (pt)	1992-12-31
NZ240481A (en)	1994-06-27
DE69120287T2 (de)	1996-10-10
PH30665A (en)	1997-09-16
DE69120287D1 (en)	1996-07-18
US5288757A (en)	1994-02-22
GR3020355T3 (en)	1996-09-30
PT99435B (pt)	1999-04-30
MX9101958A (es)	1992-07-08
JP2001026574A (ja)	2001-01-30
CA2094806C (en)	2004-11-02
IE913874A1 (en)	1992-05-20
US5214206A (en)	1993-05-25
AU657928B2 (en)	1995-03-30
AU8959791A (en)	1992-06-11

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TR199801255T2 (xx)	1998-10-21	Vitronektin resept�r antagonistleri.
EE9800223A (et)	1998-12-15	Fenantridiinid, neid sisaldavad ravimid ja nende kasutamine
ATE216590T1 (de)	2002-05-15	Arzneimittelformulierungen für il-12
ATE231872T1 (de)	2003-02-15	Thiazolopyrimidinderivate
ATE255589T1 (de)	2003-12-15	Kristallin form i von clarithromycin
DE69326776D1 (de)	1999-11-18	Verwendung von n-arylmethylen ethylendiamintriacetate, n-arylmethylen iminodiacetat oder n,n'-diarylmethylen ethylendiamindiacetat gegen oxidativen stress
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DE69102704D1 (de)	1994-08-04	Orales, melatonin enthaltendes arzneimittel.
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IT1255678B (it)	1995-11-10	Composizioni farmaceutiche per la somministrazione di paratormone, suoi frammenti biologicamente attivi o peptidi correlati per via rettale.