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PT98148A - Processo de preparacao de r(+)-2-{4-{(tetra-hidro-2-furanil)carbonil}-1-piperazinil}-6,7-dimetoxi-4-quinazolinamina e de seus sais farmaceuticamente aceitaveis,substancialmente isentos de enantiomero s(-) e de composicoes farmaceuticas - Google Patents

Processo de preparacao de r(+)-2-{4-{(tetra-hidro-2-furanil)carbonil}-1-piperazinil}-6,7-dimetoxi-4-quinazolinamina e de seus sais farmaceuticamente aceitaveis,substancialmente isentos de enantiomero s(-) e de composicoes farmaceuticas

Info

Publication number
PT98148A
PT98148A PT98148A PT9814891A PT98148A PT 98148 A PT98148 A PT 98148A PT 98148 A PT98148 A PT 98148A PT 9814891 A PT9814891 A PT 9814891A PT 98148 A PT98148 A PT 98148A
Authority
PT
Portugal
Prior art keywords
furanyl
tetrahydro
carbonyl
quinazolinamine
pyrazazyl
Prior art date
Application number
PT98148A
Other languages
English (en)
Other versions
PT98148B (pt
Inventor
Bruce W Horrom
John J Kyncl
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of PT98148A publication Critical patent/PT98148A/pt
Publication of PT98148B publication Critical patent/PT98148B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT98148A 1990-06-29 1991-06-28 Processo de preparacao de r(+)-2-{4-{(tetra-hidro-2-furanil)carbonil}-1-piperazinil}-6,7-dimetoxi-4-quinazolinamina e de seus sais farmaceuticamente aceitaveis,substancialmente isentos de enantiomero s(-) e de composicoes farmaceuticas PT98148B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/546,349 US5212176A (en) 1990-06-29 1990-06-29 R(+)-terazosin
CA002086974A CA2086974C (en) 1990-06-29 1993-01-08 R(+)-terazosin

Publications (2)

Publication Number Publication Date
PT98148A true PT98148A (pt) 1993-08-31
PT98148B PT98148B (pt) 1998-12-31

Family

ID=25675811

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98148A PT98148B (pt) 1990-06-29 1991-06-28 Processo de preparacao de r(+)-2-{4-{(tetra-hidro-2-furanil)carbonil}-1-piperazinil}-6,7-dimetoxi-4-quinazolinamina e de seus sais farmaceuticamente aceitaveis,substancialmente isentos de enantiomero s(-) e de composicoes farmaceuticas

Country Status (14)

Country Link
US (1) US5212176A (pt)
EP (1) EP0536329B1 (pt)
JP (1) JPH07119222B2 (pt)
AT (1) ATE136779T1 (pt)
AU (1) AU654148B2 (pt)
CA (1) CA2086974C (pt)
DE (1) DE69118889T2 (pt)
DK (1) DK0536329T3 (pt)
ES (1) ES2089224T3 (pt)
GR (1) GR3020364T3 (pt)
IE (1) IE72967B1 (pt)
IL (1) IL98562A (pt)
PT (1) PT98148B (pt)
WO (1) WO1992000073A1 (pt)

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DE19861323B4 (de) * 1998-12-08 2006-02-16 Robert Bosch Gmbh Verfahren zur Übertragung von Kurznachrichten
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US6200573B1 (en) 1999-12-03 2001-03-13 Starcor Pharmaceuticals, Inc. Method of medical management for lower urinary tract symptoms and benign prostatic hyperplasia
US7335803B2 (en) 2001-10-19 2008-02-26 Allergan, Inc. Methods and compositions for modulating alpha adrenergic receptor activity
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US7276522B2 (en) 2002-05-21 2007-10-02 Allergan, Inc. 4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones, 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds
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BRPI0906925A2 (pt) 2008-01-18 2019-09-24 Allergan Inc agentes adrenérgicos do subtipo alfa 2 seletivos e métodos de uso dos mesmos
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CA2724435A1 (en) 2008-05-16 2009-11-19 Allergan, Inc. Selective subtype alpha 2 adrenergic agents and methods for use thereof
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WO2010091209A1 (en) 2009-02-06 2010-08-12 Allergan, Inc. Pyridine compounds as subtype selective modulators of alpha2b and/or alpha 2c adrenergic receptors
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Also Published As

Publication number Publication date
ATE136779T1 (de) 1996-05-15
ES2089224T3 (es) 1996-10-01
EP0536329A4 (en) 1993-05-19
JPH05507280A (ja) 1993-10-21
EP0536329A1 (en) 1993-04-14
WO1992000073A1 (en) 1992-01-09
DE69118889D1 (en) 1996-05-23
IL98562A (en) 1995-12-31
PT98148B (pt) 1998-12-31
AU654148B2 (en) 1994-10-27
JPH07119222B2 (ja) 1995-12-20
CA2086974A1 (en) 1994-07-09
CA2086974C (en) 2001-04-10
AU8323191A (en) 1992-01-23
DK0536329T3 (da) 1996-08-12
IE72967B1 (en) 1997-05-07
EP0536329B1 (en) 1996-04-17
IE912086A1 (en) 1992-01-01
US5212176A (en) 1993-05-18
GR3020364T3 (en) 1996-09-30
DE69118889T2 (de) 1996-11-07

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