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PT97047A - Processo de preparacao de compostos de 1-carboxialquilquinoxalina-2,3(1h,4h)-diona e de composicoes farmaceuticas que os contem - Google Patents

Processo de preparacao de compostos de 1-carboxialquilquinoxalina-2,3(1h,4h)-diona e de composicoes farmaceuticas que os contem

Info

Publication number
PT97047A
PT97047A PT97047A PT9704791A PT97047A PT 97047 A PT97047 A PT 97047A PT 97047 A PT97047 A PT 97047A PT 9704791 A PT9704791 A PT 9704791A PT 97047 A PT97047 A PT 97047A
Authority
PT
Portugal
Prior art keywords
carboxychlycylinoxaline
diona
alkyl
pharmaceutical compositions
represents hydrogen
Prior art date
Application number
PT97047A
Other languages
English (en)
Other versions
PT97047B (pt
Inventor
Peter Faarup
Anker Steen Jorgensen
Carsten Enggaard Stidsen
Frederik Christian Gronvald
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of PT97047A publication Critical patent/PT97047A/pt
Publication of PT97047B publication Critical patent/PT97047B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40Benzopyrazines
    • C07D241/44Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT97047A 1990-03-16 1991-03-15 Processo de preparacao de compostos de 1-carboxialquilquinoxalina-2,3(1h,4h)-diona e de composicoes farmaceuticas que os contem PT97047B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK069790A DK69790D0 (da) 1990-03-16 1990-03-16 Heterocykliske forbindelser, deres fremstilling af anvendelse

Publications (2)

Publication Number Publication Date
PT97047A true PT97047A (pt) 1991-10-31
PT97047B PT97047B (pt) 1998-07-31

Family

ID=8096500

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97047A PT97047B (pt) 1990-03-16 1991-03-15 Processo de preparacao de compostos de 1-carboxialquilquinoxalina-2,3(1h,4h)-diona e de composicoes farmaceuticas que os contem

Country Status (20)

Country Link
US (1) US5166155A (pt)
EP (1) EP0520024B1 (pt)
JP (1) JPH05505810A (pt)
AT (1) ATE139530T1 (pt)
AU (1) AU652560B2 (pt)
CA (1) CA2078429A1 (pt)
CS (1) CS68791A3 (pt)
DE (1) DE69120400T2 (pt)
DK (2) DK69790D0 (pt)
ES (1) ES2089204T3 (pt)
FI (1) FI924118A (pt)
GR (1) GR3020560T3 (pt)
HU (1) HUT62274A (pt)
IE (1) IE910685A1 (pt)
IL (1) IL97405A (pt)
NO (1) NO179949C (pt)
NZ (1) NZ237431A (pt)
PT (1) PT97047B (pt)
WO (1) WO1991013878A1 (pt)
ZA (1) ZA911779B (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT101004B (pt) * 1991-10-26 1999-10-29 Schering Ag Derivados da quinoxalina, processo para a sua preparacao e composicoes farmaceuticas que os contem
US6057304A (en) 1992-10-26 2000-05-02 Schering Aktiengesellschaft Quinoxaline-phosphonic acid derivatives
ATE404201T1 (de) * 1992-06-22 2008-08-15 Univ California Glycinrezeptorantagonisten und ihre verwendung
FR2696466B1 (fr) * 1992-10-02 1994-11-25 Rhone Poulenc Rorer Sa Dérivés de 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, leur préparation et les médicaments les contenant.
IL109397A0 (en) * 1993-04-28 1994-07-31 Schering Ag Quinoxalinedione derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
DE4314592A1 (de) * 1993-04-28 1994-11-03 Schering Ag Benzo(f)chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln
US5631373A (en) * 1993-11-05 1997-05-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones
DE4340045A1 (de) * 1993-11-24 1995-06-01 Basf Ag Neue Chinoxaline und Arzneimittel daraus
US5620978A (en) * 1994-01-03 1997-04-15 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon 8-aza, 6-aza and 6,8-diaza-1,4-dihydroquinoxaline-2,3-diones and the use thereof as antagonists for the glycine/NMDA receptor
DE4428152A1 (de) * 1994-06-22 1996-01-04 Basf Ag Neue Amido-chinoxalindione, ihrer Herstellung und Verwendung
DE4436852A1 (de) * 1994-10-14 1996-04-18 Basf Ag Pyrrolyl-tetrahydrobenzochinoxalindione, ihre Herstellung und Verwendung
DE4439492A1 (de) * 1994-10-25 1996-05-02 Schering Ag Neue Chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln
US5559447A (en) * 1994-11-17 1996-09-24 Cypress Semiconductor Output buffer with variable output impedance
DE19519979A1 (de) * 1995-05-24 1996-11-28 Schering Ag Neue Chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln
DE19521058A1 (de) * 1995-06-09 1996-12-12 Basf Ag Verfahren zur Herstellung von Aromaten enthaltenden Polyetherpolyolen
DE19545251A1 (de) * 1995-11-24 1997-05-28 Schering Ag Neue Chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln
GB9604400D0 (en) 1996-03-01 1996-05-01 Pfizer Ltd Compounds useful in therapy
DE19624808A1 (de) 1996-06-21 1998-01-02 Basf Ag Pyrrolylchinoxalindione, ihre Herstellung und Verwendung
EP0934326B1 (de) * 1996-10-24 2006-05-03 Novartis AG Substituierte aminoalkanphosphonsäuren

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO179551C (no) * 1987-11-10 1996-10-30 Novo Nordisk As Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser
DK715888D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
DK716188D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse

Also Published As

Publication number Publication date
IL97405A0 (en) 1992-06-21
WO1991013878A1 (en) 1991-09-19
EP0520024A1 (en) 1992-12-30
AU652560B2 (en) 1994-09-01
EP0520024B1 (en) 1996-06-19
NO923586L (no) 1992-09-15
US5166155A (en) 1992-11-24
FI924118A0 (fi) 1992-09-15
NO923586D0 (no) 1992-09-15
DE69120400T2 (de) 1996-12-19
ES2089204T3 (es) 1996-10-01
IL97405A (en) 1995-12-08
DK69790D0 (da) 1990-03-16
IE910685A1 (en) 1991-09-25
NO179949C (no) 1997-01-15
HUT62274A (en) 1993-04-28
NO179949B (no) 1996-10-07
PT97047B (pt) 1998-07-31
ATE139530T1 (de) 1996-07-15
CS68791A3 (en) 1992-02-19
CA2078429A1 (en) 1991-09-17
JPH05505810A (ja) 1993-08-26
DK0520024T3 (da) 1996-10-14
GR3020560T3 (en) 1996-10-31
NZ237431A (en) 1993-09-27
ZA911779B (en) 1991-12-24
FI924118A (fi) 1992-09-15
DE69120400D1 (de) 1996-07-25
HU9202953D0 (en) 1992-12-28
AU7576791A (en) 1991-10-10

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19910710

FG3A Patent granted, date of granting

Effective date: 19980415

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19991031