DK0520024T3 - Quinoxalinforbindelser og deres fremstilling og anvendelse - Google Patents
Quinoxalinforbindelser og deres fremstilling og anvendelseInfo
- Publication number
- DK0520024T3 DK0520024T3 DK91906855.1T DK91906855T DK0520024T3 DK 0520024 T3 DK0520024 T3 DK 0520024T3 DK 91906855 T DK91906855 T DK 91906855T DK 0520024 T3 DK0520024 T3 DK 0520024T3
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- represents hydrogen
- preparation
- compounds
- aryl
- Prior art date
Links
- 125000001567 quinoxalinyl group Chemical class N1=C(C=NC2=CC=CC=C12)* 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 150000002431 hydrogen Chemical group 0.000 abstract 4
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- -1 branched chains Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 208000020016 psychiatric disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
- C07D241/52—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK069790A DK69790D0 (da) | 1990-03-16 | 1990-03-16 | Heterocykliske forbindelser, deres fremstilling af anvendelse |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0520024T3 true DK0520024T3 (da) | 1996-10-14 |
Family
ID=8096500
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK069790A DK69790D0 (da) | 1990-03-16 | 1990-03-16 | Heterocykliske forbindelser, deres fremstilling af anvendelse |
| DK91906855.1T DK0520024T3 (da) | 1990-03-16 | 1991-03-15 | Quinoxalinforbindelser og deres fremstilling og anvendelse |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK069790A DK69790D0 (da) | 1990-03-16 | 1990-03-16 | Heterocykliske forbindelser, deres fremstilling af anvendelse |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5166155A (da) |
| EP (1) | EP0520024B1 (da) |
| JP (1) | JPH05505810A (da) |
| AT (1) | ATE139530T1 (da) |
| AU (1) | AU652560B2 (da) |
| CA (1) | CA2078429A1 (da) |
| CS (1) | CS68791A3 (da) |
| DE (1) | DE69120400T2 (da) |
| DK (2) | DK69790D0 (da) |
| ES (1) | ES2089204T3 (da) |
| FI (1) | FI924118A7 (da) |
| GR (1) | GR3020560T3 (da) |
| HU (1) | HUT62274A (da) |
| IE (1) | IE910685A1 (da) |
| IL (1) | IL97405A (da) |
| NO (1) | NO179949C (da) |
| NZ (1) | NZ237431A (da) |
| PT (1) | PT97047B (da) |
| WO (1) | WO1991013878A1 (da) |
| ZA (1) | ZA911779B (da) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT101004B (pt) * | 1991-10-26 | 1999-10-29 | Schering Ag | Derivados da quinoxalina, processo para a sua preparacao e composicoes farmaceuticas que os contem |
| US6057304A (en) * | 1992-10-26 | 2000-05-02 | Schering Aktiengesellschaft | Quinoxaline-phosphonic acid derivatives |
| PT647137E (pt) * | 1992-06-22 | 2008-11-24 | Univ California | Antagonistas dos receptores da glicina e a sua utilização |
| FR2696466B1 (fr) * | 1992-10-02 | 1994-11-25 | Rhone Poulenc Rorer Sa | Dérivés de 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, leur préparation et les médicaments les contenant. |
| IL109397A0 (en) * | 1993-04-28 | 1994-07-31 | Schering Ag | Quinoxalinedione derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same |
| DE4314592A1 (de) * | 1993-04-28 | 1994-11-03 | Schering Ag | Benzo(f)chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln |
| US5631373A (en) * | 1993-11-05 | 1997-05-20 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon | Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones |
| DE4340045A1 (de) * | 1993-11-24 | 1995-06-01 | Basf Ag | Neue Chinoxaline und Arzneimittel daraus |
| IL112235A (en) * | 1994-01-03 | 2000-06-29 | Acea Pharm Inc | 1,4-dihydro-pyrido¬2,3-b¾pyrazine-2,3-dione (5 or 8) oxide derivatives and pharmaceutical compositions containing them |
| DE4428152A1 (de) * | 1994-06-22 | 1996-01-04 | Basf Ag | Neue Amido-chinoxalindione, ihrer Herstellung und Verwendung |
| DE4436852A1 (de) * | 1994-10-14 | 1996-04-18 | Basf Ag | Pyrrolyl-tetrahydrobenzochinoxalindione, ihre Herstellung und Verwendung |
| DE4439492A1 (de) * | 1994-10-25 | 1996-05-02 | Schering Ag | Neue Chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln |
| US5559447A (en) * | 1994-11-17 | 1996-09-24 | Cypress Semiconductor | Output buffer with variable output impedance |
| DE19519979A1 (de) * | 1995-05-24 | 1996-11-28 | Schering Ag | Neue Chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln |
| DE19521058A1 (de) * | 1995-06-09 | 1996-12-12 | Basf Ag | Verfahren zur Herstellung von Aromaten enthaltenden Polyetherpolyolen |
| DE19545251A1 (de) * | 1995-11-24 | 1997-05-28 | Schering Ag | Neue Chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln |
| GB9604400D0 (en) | 1996-03-01 | 1996-05-01 | Pfizer Ltd | Compounds useful in therapy |
| DE19624808A1 (de) | 1996-06-21 | 1998-01-02 | Basf Ag | Pyrrolylchinoxalindione, ihre Herstellung und Verwendung |
| ATE325128T1 (de) * | 1996-10-24 | 2006-06-15 | Novartis Pharma Gmbh | Substituierte aminoalkanphosphonsäuren |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO179551C (no) * | 1987-11-10 | 1996-10-30 | Novo Nordisk As | Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser |
| DK715888D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Quinoxalinforbindelser, deres fremstilling og anvendelse |
| DK716188D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Quinoxalinforbindelser, deres fremstilling og anvendelse |
-
1990
- 1990-03-16 DK DK069790A patent/DK69790D0/da not_active Application Discontinuation
-
1991
- 1991-03-01 IE IE068591A patent/IE910685A1/en unknown
- 1991-03-04 IL IL9740591A patent/IL97405A/en not_active IP Right Cessation
- 1991-03-11 ZA ZA911779A patent/ZA911779B/xx unknown
- 1991-03-12 US US07/667,855 patent/US5166155A/en not_active Expired - Fee Related
- 1991-03-14 NZ NZ237431A patent/NZ237431A/xx unknown
- 1991-03-15 AU AU75767/91A patent/AU652560B2/en not_active Ceased
- 1991-03-15 EP EP91906855A patent/EP0520024B1/en not_active Expired - Lifetime
- 1991-03-15 AT AT91906855T patent/ATE139530T1/de not_active IP Right Cessation
- 1991-03-15 FI FI924118A patent/FI924118A7/fi not_active Application Discontinuation
- 1991-03-15 PT PT97047A patent/PT97047B/pt not_active IP Right Cessation
- 1991-03-15 DK DK91906855.1T patent/DK0520024T3/da active
- 1991-03-15 WO PCT/DK1991/000078 patent/WO1991013878A1/en not_active Ceased
- 1991-03-15 DE DE69120400T patent/DE69120400T2/de not_active Expired - Fee Related
- 1991-03-15 CA CA002078429A patent/CA2078429A1/en not_active Abandoned
- 1991-03-15 HU HU922953A patent/HUT62274A/hu unknown
- 1991-03-15 JP JP91506759A patent/JPH05505810A/ja active Pending
- 1991-03-15 CS CS91687A patent/CS68791A3/cs unknown
- 1991-03-15 ES ES91906855T patent/ES2089204T3/es not_active Expired - Lifetime
-
1992
- 1992-09-15 NO NO923586A patent/NO179949C/no unknown
-
1996
- 1996-07-17 GR GR960401929T patent/GR3020560T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CS68791A3 (en) | 1992-02-19 |
| NZ237431A (en) | 1993-09-27 |
| CA2078429A1 (en) | 1991-09-17 |
| GR3020560T3 (en) | 1996-10-31 |
| AU7576791A (en) | 1991-10-10 |
| AU652560B2 (en) | 1994-09-01 |
| IE910685A1 (en) | 1991-09-25 |
| WO1991013878A1 (en) | 1991-09-19 |
| ES2089204T3 (es) | 1996-10-01 |
| EP0520024A1 (en) | 1992-12-30 |
| NO179949C (no) | 1997-01-15 |
| PT97047A (pt) | 1991-10-31 |
| HU9202953D0 (en) | 1992-12-28 |
| HUT62274A (en) | 1993-04-28 |
| FI924118A0 (fi) | 1992-09-15 |
| NO179949B (no) | 1996-10-07 |
| ATE139530T1 (de) | 1996-07-15 |
| NO923586D0 (no) | 1992-09-15 |
| PT97047B (pt) | 1998-07-31 |
| IL97405A (en) | 1995-12-08 |
| IL97405A0 (en) | 1992-06-21 |
| NO923586L (no) | 1992-09-15 |
| FI924118L (fi) | 1992-09-15 |
| EP0520024B1 (en) | 1996-06-19 |
| DK69790D0 (da) | 1990-03-16 |
| DE69120400D1 (de) | 1996-07-25 |
| ZA911779B (en) | 1991-12-24 |
| US5166155A (en) | 1992-11-24 |
| DE69120400T2 (de) | 1996-12-19 |
| FI924118A7 (fi) | 1992-09-15 |
| JPH05505810A (ja) | 1993-08-26 |
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