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PT932402E - Metodo de utilizacao de inibidores de ciclooxigenase-2 no tratamento e prevencaode neoplasia - Google Patents

Metodo de utilizacao de inibidores de ciclooxigenase-2 no tratamento e prevencaode neoplasia

Info

Publication number
PT932402E
PT932402E PT97911746T PT97911746T PT932402E PT 932402 E PT932402 E PT 932402E PT 97911746 T PT97911746 T PT 97911746T PT 97911746 T PT97911746 T PT 97911746T PT 932402 E PT932402 E PT 932402E
Authority
PT
Portugal
Prior art keywords
neoplasia
treatment
prevencaode
cyclooxygenase
inhibitors
Prior art date
Application number
PT97911746T
Other languages
English (en)
Inventor
Karen Seibert
Jaime Masferrer
Gary B Gordon
Original Assignee
Searle Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21843754&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT932402(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Searle Llc filed Critical Searle Llc
Publication of PT932402E publication Critical patent/PT932402E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10Sulfides; Sulfoxides; Sulfones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41781,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/4211,3-Oxazoles, e.g. pemoline, trimethadione
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
PT97911746T 1996-10-15 1997-10-14 Metodo de utilizacao de inibidores de ciclooxigenase-2 no tratamento e prevencaode neoplasia PT932402E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2849496P 1996-10-15 1996-10-15

Publications (1)

Publication Number Publication Date
PT932402E true PT932402E (pt) 2004-11-30

Family

ID=21843754

Family Applications (2)

Application Number Title Priority Date Filing Date
PT97911746T PT932402E (pt) 1996-10-15 1997-10-14 Metodo de utilizacao de inibidores de ciclooxigenase-2 no tratamento e prevencaode neoplasia
PT04011516T PT1479385E (pt) 1996-10-15 1997-10-14 Utilização de inibidores de ciclo-oxigenase 2 no tratamento e na prevenção de neoplasias

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT04011516T PT1479385E (pt) 1996-10-15 1997-10-14 Utilização de inibidores de ciclo-oxigenase 2 no tratamento e na prevenção de neoplasias

Country Status (25)

Country Link
EP (3) EP0932402B1 (pt)
JP (1) JP2001503395A (pt)
KR (1) KR20000049138A (pt)
CN (2) CN100558356C (pt)
AT (2) ATE399547T1 (pt)
AU (1) AU742645B2 (pt)
BR (1) BR9712314A (pt)
CA (1) CA2267186C (pt)
CZ (1) CZ298022B6 (pt)
DE (2) DE69729946T2 (pt)
DK (2) DK1479385T3 (pt)
ES (2) ES2224222T3 (pt)
HK (1) HK1025518A1 (pt)
HU (1) HU227564B1 (pt)
IL (3) IL154501A0 (pt)
NO (1) NO326822B1 (pt)
NZ (3) NZ506515A (pt)
PT (2) PT932402E (pt)
RO (1) RO120172B1 (pt)
RU (1) RU2239429C2 (pt)
SK (1) SK284788B6 (pt)
TR (1) TR199900827T2 (pt)
TW (1) TWI235060B (pt)
UA (1) UA67732C2 (pt)
WO (1) WO1998016227A1 (pt)

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US20040122011A1 (en) * 1998-12-23 2004-06-24 Pharmacia Corporation Method of using a COX-2 inhibitor and a TACE inhibitors as a combination therapy
US20040053900A1 (en) * 1998-12-23 2004-03-18 Pharmacia Corporation Method of using a COX-2 inhibitor and an aromatase inhibitor as a combination therapy
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Also Published As

Publication number Publication date
ATE271385T1 (de) 2004-08-15
AU742645B2 (en) 2002-01-10
CN1660083A (zh) 2005-08-31
NZ506515A (en) 2002-05-31
NZ334921A (en) 2001-03-30
RO120172B1 (ro) 2005-10-28
DE69729946T2 (de) 2005-01-20
IL154501A0 (en) 2003-09-17
CN1332661C (zh) 2007-08-22
PT1479385E (pt) 2008-09-02
KR20000049138A (ko) 2000-07-25
CN1244122A (zh) 2000-02-09
ATE399547T1 (de) 2008-07-15
NO991793L (no) 1999-04-15
IL128568A0 (en) 2000-01-31
TR199900827T2 (xx) 1999-07-21
JP2001503395A (ja) 2001-03-13
CA2267186C (en) 2002-05-14
UA67732C2 (uk) 2004-07-15
TWI235060B (en) 2005-07-01
SK284788B6 (sk) 2005-11-03
NO326822B1 (no) 2009-02-23
HUP9904221A2 (hu) 2000-09-28
CZ298022B6 (cs) 2007-05-30
NZ509755A (en) 2002-09-27
HUP9904221A3 (en) 2000-12-28
DE69729946D1 (de) 2004-08-26
RU2239429C2 (ru) 2004-11-10
EP0932402B1 (en) 2004-07-21
ES2224222T3 (es) 2005-03-01
EP1977749A1 (en) 2008-10-08
HU227564B1 (en) 2011-08-29
BR9712314A (pt) 1999-08-31
AU4904897A (en) 1998-05-11
DK1479385T3 (da) 2008-08-04
SK46299A3 (en) 2000-03-13
WO1998016227A1 (en) 1998-04-23
EP1479385B1 (en) 2008-07-02
DK0932402T3 (da) 2004-11-08
CN100558356C (zh) 2009-11-11
CZ117199A3 (cs) 1999-07-14
NO991793D0 (no) 1999-04-15
EP0932402A1 (en) 1999-08-04
EP1479385A1 (en) 2004-11-24
IL165816A0 (en) 2006-01-15
ES2308068T3 (es) 2008-12-01
DE69738815D1 (de) 2008-08-14
HK1025518A1 (en) 2000-11-17
CA2267186A1 (en) 1998-04-23

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