[go: up one dir, main page]

ATE294574T1 - Kombination therapie mit pentafluorobenzenesulfonamid und platin-derivate - Google Patents

Kombination therapie mit pentafluorobenzenesulfonamid und platin-derivate

Info

Publication number
ATE294574T1
ATE294574T1 AT00953755T AT00953755T ATE294574T1 AT E294574 T1 ATE294574 T1 AT E294574T1 AT 00953755 T AT00953755 T AT 00953755T AT 00953755 T AT00953755 T AT 00953755T AT E294574 T1 ATE294574 T1 AT E294574T1
Authority
AT
Austria
Prior art keywords
pentafluorobenzenesulfonamide
combination therapy
platinum derivatives
platinum
derivatives
Prior art date
Application number
AT00953755T
Other languages
English (en)
Inventor
Susan Schwendner
Pieter Timmermans
Jacqueline Walling
Original Assignee
Tularik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tularik Inc filed Critical Tularik Inc
Application granted granted Critical
Publication of ATE294574T1 publication Critical patent/ATE294574T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Weting (AREA)
AT00953755T 1999-07-29 2000-07-27 Kombination therapie mit pentafluorobenzenesulfonamid und platin-derivate ATE294574T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14643699P 1999-07-29 1999-07-29
PCT/US2000/020763 WO2001008693A2 (en) 1999-07-29 2000-07-27 Combination therapy using pentafluorobenzenesulfonamide and platin compound

Publications (1)

Publication Number Publication Date
ATE294574T1 true ATE294574T1 (de) 2005-05-15

Family

ID=22517356

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00953755T ATE294574T1 (de) 1999-07-29 2000-07-27 Kombination therapie mit pentafluorobenzenesulfonamid und platin-derivate

Country Status (16)

Country Link
US (1) US6355628B1 (de)
EP (1) EP1206256B8 (de)
JP (1) JP2003505513A (de)
KR (1) KR100685059B1 (de)
CN (1) CN1181819C (de)
AT (1) ATE294574T1 (de)
AU (1) AU775305B2 (de)
CA (1) CA2380078C (de)
DE (1) DE60019937T2 (de)
DK (1) DK1206256T3 (de)
ES (1) ES2241639T3 (de)
IL (2) IL147890A0 (de)
PT (1) PT1206256E (de)
RU (1) RU2268054C2 (de)
WO (1) WO2001008693A2 (de)
ZA (1) ZA200200889B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT896533E (pt) * 1996-02-22 2004-02-27 Tularik Inc Pentafluorobenzenosulfonamidas e analogos
IL127965A0 (en) * 1996-07-19 1999-11-30 Tularik Inc Pentafluorobenzenesulfonamide derivatives analogs thereof and pharmaceutical compositions containing the same
EP1115701B1 (de) * 1998-09-23 2003-05-21 Tularik Inc. Arylsulfonanilid-harnstoffe
US20050250854A1 (en) * 2000-11-03 2005-11-10 Amgen Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
US6822001B2 (en) 2000-11-03 2004-11-23 Tularik Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
FR2834641B1 (fr) * 2002-01-14 2005-04-22 Ct Regional De Lutte Contre Le Protection de la neurotoxicite de l'oxaliplatine par administration de calcium et de magnesium
CN1968685B (zh) * 2003-11-19 2014-05-14 张立新 互动药物的筛选
US10238831B2 (en) 2013-09-08 2019-03-26 Qool Therapeutics, Inc. Temperature measurement and feedback for therapeutic hypothermia
JP6722685B2 (ja) 2015-02-23 2020-07-15 クール セラピューティクス， インコーポレイテッド 凍結された粒子の気管内送達のためのシステムおよび方法
EP3676255B1 (de) 2017-08-29 2025-04-16 Rutgers, The State University University Of New Jersey Therapeutische indazole
WO2019056120A1 (en) * 2017-09-21 2019-03-28 Dalriada Therapeutics Inc. PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1955207A (en) 1931-09-16 1934-04-17 Ig Farbenindustrie Ag Mothproofing agent
US2402623A (en) 1943-06-24 1946-06-25 Rohm & Haas Nu-nitroaryl haloarylsulphonamides
CH361275A (de) 1957-09-10 1962-04-15 Geigy Ag J R Verfahren zur Herstellung von neuen Arylsulfonarylamiden
GB1242057A (en) 1968-07-04 1971-08-11 Ici Ltd Derivatives of 4-hydroxytetrafluoropyridine and the use thereof as plant growth regulators
NL174644C (nl) 1970-04-13 1984-07-16 Minnesota Mining & Mfg Werkwijze ter bereiding van een herbicide verbinding; tevens werkwijze voor de bereiding van een preparaat met herbicide werking.
SE447902B (sv) * 1977-10-19 1986-12-22 Johnson Matthey Co Ltd Cis-koordinationsforening av platina och komposition innehallande foreningen
DE3623184A1 (de) 1986-07-10 1988-01-14 Kali Chemie Ag Verfahren zur herstellung von n-fluorsulfonamiden
US4883914A (en) 1987-08-17 1989-11-28 American Cyanamid Company Benzenesulfonyl carboxamide compounds useful as herbicidal agents
DE3804990A1 (de) 1988-02-18 1989-08-31 Basf Ag Herbizid wirksame, heterocyclisch substituierte sulfonamide
FR2645537B1 (fr) 1989-04-05 1994-03-04 Fabre Medicament Pierre Nouveaux sulfonamides derives d'acides benzocycliques ou benzoheterocycliques, leur preparation et leur application en therapeutique
FR2665440B1 (fr) 1990-07-31 1994-02-04 Lipha Nouveaux cycloalkylsulfonamides substitues, procedes de preparation et medicaments les contenant.
US5189211A (en) 1990-08-01 1993-02-23 Taisho Pharmaceutical Co., Ltd. Sulfonamide derivatives
EP0472053B1 (de) 1990-08-20 1998-06-17 Eisai Co., Ltd. Sulfonamid-Derivate
RU2088288C1 (ru) * 1993-07-29 1997-08-27 Московский областной научно-исследовательский клинический институт Способ лечения больных местнораспространенными формами рака
RU2098096C1 (ru) * 1993-10-11 1997-12-10 Московский научно-исследовательский онкологический институт им.П.А.Герцена Средства, подавляющие рост раковых клеток
AU6112896A (en) 1995-06-07 1996-12-30 Sugen, Inc. Tyrphostin-like compounds for the treatment of cell prolifer ative disorders or cell differentiation disorders
PT896533E (pt) 1996-02-22 2004-02-27 Tularik Inc Pentafluorobenzenosulfonamidas e analogos
IL127965A0 (en) * 1996-07-19 1999-11-30 Tularik Inc Pentafluorobenzenesulfonamide derivatives analogs thereof and pharmaceutical compositions containing the same
RU2239429C2 (ru) * 1996-10-15 2004-11-10 Джи. Ди. Сирл Энд Ко. Способ применения ингибиторов циклооксигеназы-2 для лечения и профилактики неоплазии
UA70294C2 (en) * 1996-11-19 2004-10-15 Use of cyclooxygenase-2 inhibitors as anti-angiogeuse of cyclooxygenase-2 inhibitors as anti-angiogenic agents nic agents
US5773236A (en) 1997-04-25 1998-06-30 Molecule Probes, Inc. Assay for glutathiane transferase using polyhaloaryl-substituted reporter molecules
EP1090014B1 (de) * 1998-06-25 2003-09-03 Tularik Inc. Arylsulfonanilid-phosphate
EP1115701B1 (de) * 1998-09-23 2003-05-21 Tularik Inc. Arylsulfonanilid-harnstoffe
AU2190700A (en) * 1998-12-17 2000-07-03 Tularik Inc. Tubulin-binding agents
CO5170498A1 (es) * 1999-05-28 2002-06-27 Abbott Lab Biaril sulfonamidas son utiles como inhibidores de proliferacion celular

Also Published As

Publication number Publication date
RU2268054C2 (ru) 2006-01-20
RU2002105374A (ru) 2004-01-10
EP1206256B1 (de) 2005-05-04
ES2241639T3 (es) 2005-11-01
KR20020050225A (ko) 2002-06-26
US6355628B1 (en) 2002-03-12
CA2380078A1 (en) 2001-02-08
IL147890A (en) 2007-07-04
DE60019937D1 (de) 2005-06-09
DE60019937T2 (de) 2006-05-04
CN1181819C (zh) 2004-12-29
IL147890A0 (en) 2002-08-14
AU775305B2 (en) 2004-07-29
AU6615200A (en) 2001-02-19
JP2003505513A (ja) 2003-02-12
ZA200200889B (en) 2003-03-26
EP1206256A2 (de) 2002-05-22
CN1367690A (zh) 2002-09-04
CA2380078C (en) 2008-05-06
KR100685059B1 (ko) 2007-02-22
EP1206256B8 (de) 2005-06-29
DK1206256T3 (da) 2005-08-15
PT1206256E (pt) 2005-09-30
WO2001008693A2 (en) 2001-02-08
WO2001008693A3 (en) 2001-05-25

Similar Documents

Publication Publication Date Title
ATE261974T1 (de) Hoch-lipophile campothecin-derivate
NO20050807L (no) Farmasoytiske sammensetninger som innbefatter dekstrometorfan og kinidin for behandling av neurologiske forstyrrelser
IS7857A (is) Setnar pýrróló-pýrasól afleiður sem kínasa hindrar
ATE414536T1 (de) Kombinationstherapien gegen b-zell-lymphome beinhaltend die verabreichung von anti-cd20- antikörpern
DE60001974D1 (de) Derivate von flavonen, xanthonen und kumarinen
BRPI0407897A (pt) derivados de cianopiridina úteis no tratamento de cáncer e outros distúrbios
BR0116323A (pt) Compostos de heterociclilindazol e -azaindazol como ligandos de 5-hidroxitriptamina-6
TW200407326A (en) Pyrimido compounds having antiproliferative activity
ATE408601T1 (de) Fredericamycin-derivate
EP1783126A3 (de) N-Oxide von N-Phenyl-2-Pyrimidinamin Derivaten
DE69834923D1 (en) Hochgradig lipophile camptothecin-derivate
DE60003583D1 (de) Arylaminderivate und ihre verwendung als antitelomerasemittel
DE60143911D1 (de) Antitumorzusammensetzungen welche ecteinascidin 743 enthalten
BR0116481A (pt) Compostos de heterociclilalquilindol ou azaindol como ligandos de 5-hidroxitriptamina-6
ATE294574T1 (de) Kombination therapie mit pentafluorobenzenesulfonamid und platin-derivate
BR0108728A (pt) Combinação farmacêutica terapêutica, e, método para tratar um c ncer.
DE60115466D1 (de) Wirkstoffvorläufer von imidazopyridin-derivaten
GEP20105095B (en) Phenylacetamido-thiazole derivatives, process for their preparation and their use as antitumor agents
WO2002070515A3 (en) Chromane derivatives, process for their preparation and their use as antitumor agents
NO20031410D0 (no) Antitumorterapi innbefattende distamycinderivater
WO2002039958A3 (en) Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
ATE390921T1 (de) Zusammensetzung mit demethylcantharidin in kombination mit platinhaltigen antikrebsmitteln und ihre verwendung
ATE306283T1 (de) Biotin-derivate und ihre konjugaten mit chelatierungsmitteln
TR200200987T2 (tr) Kanser tedavisine yönelik,ornatılmış pirroller
PT1708693E (pt) Composições farmacêuticas contendo complexos de platina com xantatos secundários e suas utilizações terapêuticas

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1206256

Country of ref document: EP

REN Ceased due to non-payment of the annual fee