PT897386E - Processo para a preparacao de um sal de magnesio de um heterociclo substituido com sulfinilo - Google Patents

Processo para a preparacao de um sal de magnesio de um heterociclo substituido com sulfinilo

Info

Publication number: PT897386E
Authority: PT; Portugal
Prior art keywords: preparing; magnesium salt; substituted heterocylic; sulfinyl substituted; sulfinyl
Prior art date: 1996-04-26

Application number

PT97921045T

Other languages

English (en)

Inventor

Jan-Ake Hogeberg

Panagiotis Ioannidis

Anders Mattson

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-26

Filing date

1997-04-22

Publication date

2002-12-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20402358&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT897386(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-04-22 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2002-12-31 Publication of PT897386E publication Critical patent/PT897386E/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

PT97921045T 1996-04-26 1997-04-22 Processo para a preparacao de um sal de magnesio de um heterociclo substituido com sulfinilo PT897386E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE9601598A SE508669C2 (sv)	1996-04-26	1996-04-26	Nytt förfarande

Publications (1)

Publication Number	Publication Date
PT897386E true PT897386E (pt)	2002-12-31

Family

ID=20402358

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT97921045T PT897386E (pt)	1996-04-26	1997-04-22	Processo para a preparacao de um sal de magnesio de um heterociclo substituido com sulfinilo

Country Status (40)

Country	Link
US (1)	US6124464A (pt)
EP (1)	EP0897386B1 (pt)
JP (1)	JP4233115B2 (pt)
KR (1)	KR100468331B1 (pt)
CN (1)	CN1100776C (pt)
AR (1)	AR006640A1 (pt)
AT (1)	ATE222904T1 (pt)
BR (1)	BR9708829A (pt)
CA (1)	CA2251636C (pt)
CZ (1)	CZ295067B6 (pt)
DE (1)	DE69714987T2 (pt)
DK (1)	DK0897386T3 (pt)
DZ (1)	DZ2209A1 (pt)
EE (1)	EE03485B1 (pt)
EG (1)	EG23874A (pt)
ES (1)	ES2180981T3 (pt)
HK (1)	HK1016978A1 (pt)
HR (1)	HRP970210B1 (pt)
HU (1)	HUP9901798A3 (pt)
ID (1)	ID16685A (pt)
IL (1)	IL126716A (pt)
IS (1)	IS1984B (pt)
MA (1)	MA24143A1 (pt)
MY (1)	MY119011A (pt)
NO (1)	NO318850B1 (pt)
NZ (1)	NZ332154A (pt)
PL (1)	PL188824B1 (pt)
PT (1)	PT897386E (pt)
RS (1)	RS49718B (pt)
RU (1)	RU2163238C2 (pt)
SA (1)	SA97170759B1 (pt)
SE (1)	SE508669C2 (pt)
SI (1)	SI0897386T1 (pt)
SK (1)	SK282752B6 (pt)
TN (1)	TNSN97068A1 (pt)
TR (1)	TR199802156T2 (pt)
TW (1)	TW420676B (pt)
UA (1)	UA51699C2 (pt)
WO (1)	WO1997041114A1 (pt)
ZA (1)	ZA973153B (pt)

Families Citing this family (44)

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SE9301830D0 (sv) *	1993-05-28	1993-05-28	Ab Astra	New compounds
US6875872B1 (en) *	1993-05-28	2005-04-05	Astrazeneca	Compounds
US6489346B1 (en)	1996-01-04	2002-12-03	The Curators Of The University Of Missouri	Substituted benzimidazole dosage forms and method of using same
US6699885B2 (en) *	1996-01-04	2004-03-02	The Curators Of The University Of Missouri	Substituted benzimidazole dosage forms and methods of using same
US6645988B2 (en) *	1996-01-04	2003-11-11	Curators Of The University Of Missouri	Substituted benzimidazole dosage forms and method of using same
US5840737A (en)	1996-01-04	1998-11-24	The Curators Of The University Of Missouri	Omeprazole solution and method for using same
DE19843413C1 (de)	1998-08-18	2000-03-30	Byk Gulden Lomberg Chem Fab	Neue Salzform von Pantoprazol
CA2347981C (en)	1998-11-18	2010-05-04	Astrazeneca Ab	Process for the manufacturing of alkaline salts of substituted sulphinyl compounds and products prepared thereby
CA2290893C (en) *	1999-11-16	2007-05-01	Bernard Charles Sherman	Magnesium omeprazole
CA2775616C (en) *	2000-08-04	2013-09-17	Takeda Pharmaceutical Company Limited	Salts of benzimidazole compound and application thereof
JP2005521662A (ja) *	2002-01-25	2005-07-21	サンタラスインコーポレイティッド	プロトンポンプ阻害剤の経粘膜送達
ATE363480T1 (de) *	2002-03-05	2007-06-15	Astrazeneca Ab	Alkylammoniumsalze von omeprazol und esomeprazol
DE10234617B4 (de) *	2002-07-29	2013-04-04	Nycomed Gmbh	Neues Salz von (S)-Pantoprazol
TW200410955A (en) *	2002-07-29	2004-07-01	Altana Pharma Ag	Novel salt of (S)-PANTOPRAZOLE
US20040235903A1 (en) *	2002-10-22	2004-11-25	Khanna Mahavir Singh	Amorphous form of esomeprazole salts
WO2004046134A2 (en) *	2002-11-18	2004-06-03	Dr. Reddy's Laboratories Limited	Crystalline form ii of esomeprazole magnesium trihydrate and process for its preparation
AU2003303240A1 (en) *	2002-12-19	2004-07-14	Eva Pharmaceutical Industries Ltd.	Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates
MXPA05009183A (es) *	2003-02-28	2005-10-20	Ranbaxy Lab Ltd	Polimorfos de s-omeprazol.
CL2004000983A1 (es)	2003-05-08	2005-03-04	Altana Pharma Ag	Composicion farmaceutica oral en forma de tableta que comprende a pantoprazol magnetico dihidratado, en donde la forma de tableta esta compuesto por un nucleo, una capa intermedia y una capa exterior; y uso de la composicion farmaceutica en ulceras y
PE20050150A1 (es)	2003-05-08	2005-03-22	Altana Pharma Ag	Una forma de dosificacion que contiene (s)-pantoprazol como ingrediente activo
WO2005012289A1 (en) *	2003-07-17	2005-02-10	Altana Pharma Ag	Novel salt of (r) - pantoprazole
US8993599B2 (en)	2003-07-18	2015-03-31	Santarus, Inc.	Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
SE0302382D0 (sv) *	2003-09-04	2003-09-04	Astrazeneca Ab	New salts II
SE0302381D0 (sv)	2003-09-04	2003-09-04	Astrazeneca Ab	New salts I
ITMI20031813A1 (it) *	2003-09-23	2005-03-24	Dinamite Dipharma S P A In Forma A Bbreviata Diph	Procedimento per la preparazione di pantoprazolo e suoi sali.
WO2005082888A1 (en) *	2004-03-01	2005-09-09	Milen Merkez Ilac Endustrisi A.S.	Process for the preparation of magnesium salt of omeprazole
US8815916B2 (en)	2004-05-25	2014-08-26	Santarus, Inc.	Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en)	2004-05-25	2014-12-09	Santarus, Inc.	Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
ES2246149B1 (es) *	2004-07-02	2007-06-01	Esteve Quimica, S.A.	Formas solidas de la sal magnesica de s-omeprazol y procedimientos para su preparacion.
US8779175B2 (en)	2004-10-25	2014-07-15	Synthonics, Inc.	Coordination complexes, pharmaceutical solutions comprising coordination complexes, and methods of treating patients
US20060141054A1 (en)	2004-10-25	2006-06-29	Thomas Piccariello	Metal coordinated compositions
US7799937B2 (en)	2004-10-25	2010-09-21	Synthonics, Inc.	Metal coordinated compositions
EP1801110A1 (en)	2005-12-22	2007-06-27	KRKA, tovarna zdravil, d.d., Novo mesto	Esomeprazole arginine salt
US7553857B2 (en)	2005-12-23	2009-06-30	Lek Pharmaceuticals D.D.	S-omeprazole magnesium
WO2007146341A2 (en)	2006-06-12	2007-12-21	Teva Pharmaceutical Industries Ltd.	Amorphous and crystalline forms of pantoprazole magnesium salt
EP1947099A1 (en)	2007-01-18	2008-07-23	LEK Pharmaceuticals D.D.	Process for solvent removal from omeprazole salts
EP2186807B1 (en)	2007-02-21	2015-01-07	Cipla Limited	Process for the preparation of esomeprazole magnesium dihydrate
EP2195309A4 (en) *	2007-10-08	2013-04-24	Hetero Drugs Ltd	SALT POLYMORPHS OF THE ESOMEPRAZOLE
EP2147918A1 (en)	2008-07-21	2010-01-27	LEK Pharmaceuticals D.D.	Process for the preparation of S-omeprazole magnesium in a stable form
WO2010097583A1 (en)	2009-02-24	2010-09-02	Cipla Limited	Esomeprazole potassium polymorph and its preparation
US20110207779A1 (en) *	2010-02-25	2011-08-25	Glenmark Generics Ltd	Process for the preparation of esomeprazole magnesium
EP2426111A1 (en)	2010-08-09	2012-03-07	Laboratorios Del. Dr. Esteve, S.A.	4-[-2-[[5-methyl-1-(2-naphtalenyl)-1h-pyrazol-3-yl]oxy]ethyl]morpholine hydrochloride amorphous solid forms
CN103467453A (zh) *	2013-09-13	2013-12-25	上海海虹实业(集团)巢湖今辰药业有限公司	一种奥美拉唑镁原料药制备方法
CN106397399A (zh) *	2015-07-29	2017-02-15	陕西合成药业股份有限公司	一种泮托拉唑镁的精制方法

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SE8301182D0 (sv) *	1983-03-04	1983-03-04	Haessle Ab	Novel compounds
GB8307865D0 (en) *	1983-03-22	1983-04-27	Fujisawa Pharmaceutical Co	Benzimidazole derivatives
FI861772A (fi) *	1985-05-07	1986-11-08	Chemie Linz Ag	Nya tieno(2,3-d)imidazolderivat och foerfarande for deras framstaellning.
FI864138A (fi) *	1985-10-16	1987-04-17	Fisons Plc	Heterocykliska blandningar.
NZ244301A (en) *	1991-09-20	1994-08-26	Merck & Co Inc	Preparation of 2-pyridylmethylsulphinylbenzimidazole and pyridoimidazole derivatives from the corresponding sulphenyl compounds
SE9301830D0 (sv) *	1993-05-28	1993-05-28	Ab Astra	New compounds
SE9302396D0 (sv) *	1993-07-09	1993-07-09	Ab Astra	A novel compound form
SE9302395D0 (sv) *	1993-07-09	1993-07-09	Ab Astra	New pharmaceutical formulation
DK0723436T3 (da) *	1994-07-08	2001-11-26	Astrazeneca Ab	Tabletteret flerenhedsdoseringsform

1996
- 1996-04-26 SE SE9601598A patent/SE508669C2/sv not_active IP Right Cessation
1997
- 1997-03-29 SA SA97170759A patent/SA97170759B1/ar unknown
- 1997-04-14 TW TW086104766A patent/TW420676B/zh not_active IP Right Cessation
- 1997-04-14 AR ARP970101488A patent/AR006640A1/es active IP Right Grant
- 1997-04-14 ZA ZA9703153A patent/ZA973153B/xx unknown
- 1997-04-15 TN TNTNSN97068A patent/TNSN97068A1/fr unknown
- 1997-04-17 MA MA24558A patent/MA24143A1/fr unknown
- 1997-04-20 DZ DZ970056A patent/DZ2209A1/fr active
- 1997-04-21 HR HR970210A patent/HRP970210B1/xx not_active IP Right Cessation
- 1997-04-22 UA UA98105319A patent/UA51699C2/uk unknown
- 1997-04-22 DE DE69714987T patent/DE69714987T2/de not_active Expired - Lifetime
- 1997-04-22 DK DK97921045T patent/DK0897386T3/da active
- 1997-04-22 CZ CZ19983398A patent/CZ295067B6/cs not_active IP Right Cessation
- 1997-04-22 EG EG32297A patent/EG23874A/xx active
- 1997-04-22 BR BR9708829A patent/BR9708829A/pt not_active Application Discontinuation
- 1997-04-22 ID IDP971342A patent/ID16685A/id unknown
- 1997-04-22 EP EP97921045A patent/EP0897386B1/en not_active Expired - Lifetime
- 1997-04-22 HU HU9901798A patent/HUP9901798A3/hu unknown
- 1997-04-22 TR TR1998/02156T patent/TR199802156T2/xx unknown
- 1997-04-22 NZ NZ332154A patent/NZ332154A/en unknown
- 1997-04-22 IL IL12671697A patent/IL126716A/xx not_active IP Right Cessation
- 1997-04-22 WO PCT/SE1997/000674 patent/WO1997041114A1/en active IP Right Grant
- 1997-04-22 SK SK1407-98A patent/SK282752B6/sk not_active IP Right Cessation
- 1997-04-22 ES ES97921045T patent/ES2180981T3/es not_active Expired - Lifetime
- 1997-04-22 PL PL97329683A patent/PL188824B1/pl not_active IP Right Cessation
- 1997-04-22 RU RU98121016/04A patent/RU2163238C2/ru not_active IP Right Cessation
- 1997-04-22 SI SI9730402T patent/SI0897386T1/xx unknown
- 1997-04-22 PT PT97921045T patent/PT897386E/pt unknown
- 1997-04-22 AT AT97921045T patent/ATE222904T1/de active
- 1997-04-22 JP JP53879697A patent/JP4233115B2/ja not_active Expired - Fee Related
- 1997-04-22 CN CN97194114A patent/CN1100776C/zh not_active Expired - Fee Related
- 1997-04-22 KR KR10-1998-0708556A patent/KR100468331B1/ko not_active IP Right Cessation
- 1997-04-22 US US08/860,825 patent/US6124464A/en not_active Expired - Lifetime
- 1997-04-22 EE EE9800363A patent/EE03485B1/xx not_active IP Right Cessation
- 1997-04-22 CA CA002251636A patent/CA2251636C/en not_active Expired - Lifetime
- 1997-04-23 MY MYPI97001748A patent/MY119011A/en unknown
1998
- 1998-10-14 RS YUP-448/98A patent/RS49718B/sr unknown
- 1998-10-19 IS IS4872A patent/IS1984B/is unknown
- 1998-10-21 NO NO19984903A patent/NO318850B1/no not_active IP Right Cessation
1999
- 1999-05-07 HK HK99102051A patent/HK1016978A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
TR199802156T2 (xx)	1999-02-22
HRP970210A2 (en)	1998-04-30
CN1100776C (zh)	2003-02-05
NO984903D0 (no)	1998-10-21
IL126716A (en)	2003-10-31
PL329683A1 (en)	1999-04-12
KR20000065018A (ko)	2000-11-06
KR100468331B1 (ko)	2005-03-16
YU44898A (sh)	1999-07-28
SI0897386T1 (en)	2002-12-31
SE508669C2 (sv)	1998-10-26
DZ2209A1 (fr)	2002-12-03
US6124464A (en)	2000-09-26
SK282752B6 (sk)	2002-12-03
PL188824B1 (pl)	2005-04-29
JP2000509067A (ja)	2000-07-18
BR9708829A (pt)	1999-08-03
SK140798A3 (en)	1999-04-13
SE9601598L (sv)	1997-10-27
AR006640A1 (es)	1999-09-08
AU711345B2 (en)	1999-10-14
HK1016978A1 (en)	1999-11-12
EP0897386B1 (en)	2002-08-28
AU2719397A (en)	1997-11-19
EE03485B1 (et)	2001-08-15
TNSN97068A1 (fr)	1999-12-31
NO318850B1 (no)	2005-05-18
HUP9901798A2 (hu)	2000-04-28
DE69714987D1 (de)	2002-10-02
SA97170759B1 (ar)	2006-09-25
IS4872A (is)	1998-10-19
UA51699C2 (uk)	2002-12-16
EP0897386A1 (en)	1999-02-24
WO1997041114A1 (en)	1997-11-06
HUP9901798A3 (en)	2003-02-28
TW420676B (en)	2001-02-01
JP4233115B2 (ja)	2009-03-04
CZ295067B6 (cs)	2005-05-18
ES2180981T3 (es)	2003-02-16
NO984903L (no)	1998-10-21
CA2251636A1 (en)	1997-11-06
SE9601598D0 (sv)	1996-04-26
HRP970210B1 (en)	2002-06-30
ID16685A (id)	1997-10-30
CN1216989A (zh)	1999-05-19
MY119011A (en)	2005-03-31
ZA973153B (en)	1997-10-27
DE69714987T2 (de)	2003-04-30
IL126716A0 (en)	1999-08-17
IS1984B (is)	2005-02-15
DK0897386T3 (da)	2002-10-28
EG23874A (en)	2007-11-27
CA2251636C (en)	2001-04-10
MA24143A1 (fr)	1997-12-31
RS49718B (sr)	2007-12-31
CZ339898A3 (cs)	1999-03-17
RU2163238C2 (ru)	2001-02-20
NZ332154A (en)	2002-03-01
ATE222904T1 (de)	2002-09-15
EE9800363A (et)	1999-04-15

Publication	Publication Date	Title
PT897386E (pt)	2002-12-31	Processo para a preparacao de um sal de magnesio de um heterociclo substituido com sulfinilo
PT1273581E (pt)	2005-06-30	Novo processo para a preparacao do sal de magnesio de s-omeprazole tri-hidratado
BR9605258A (pt)	1998-07-21	Processo para a preparaçao de um composto
BR9708234A (pt)	1999-08-03	Processo para a preparaçÃo de carbenos heterociclicos
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DE69814862D1 (de)	2003-06-26	Verfahren zur herstellung von pyridinderivaten
BR9608471A (pt)	1998-12-29	Processo para a preparação de um composto
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BR9710360A (pt)	1999-08-17	Processo para sintetizar um composto
BR9610887A (pt)	1999-07-13	Processo para a preparação de um composto
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PT1009716E (pt)	2003-04-30	Metodo para produzir borato de calcio
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BR9608904A (pt)	1999-06-29	Processo para a preparação de um composto
DE69808068D1 (de)	2002-10-24	Verfahren zur herstellung von indolderivaten
ATE219056T1 (de)	2002-06-15	Verfahren zur herstellung von alpha- bromolactamderivaten
BR9602619A (pt)	1998-09-01	Processo para preparação de um composto
BR9610294A (pt)	1999-03-16	Processo para a preparação de um composto
BR9603223A (pt)	1998-11-17	Processo para a preparação de aminocarboniltriazolinonas substituídas
PT984976E (pt)	2003-01-31	Processo para a preparacao de um derivado desoxiuridina
BR9700009A (pt)	1998-11-10	Processo para a preparação de derivados de ácido o-clorometil-fenilglioxílico