PT89371A - Processo de preparacao de 1-aralquil-1,2-di-hidropirimidina-2-tionas e de composicoes farmaceuticas que as contem - Google Patents

Processo de preparacao de 1-aralquil-1,2-di-hidropirimidina-2-tionas e de composicoes farmaceuticas que as contem

Info

Publication number: PT89371A
Authority: PT; Portugal
Prior art keywords: aralquil; hydropyrimidine; tions; dihydro; pharmaceutical compositions
Prior art date: 1987-12-31

Application number

PT89371A

Other languages

English (en)

Inventor

Lawrence Ivan Kruse

Stephen Torey Ross

Original Assignee

Smithkline Beckman Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-12-31

Filing date

1988-12-30

Publication date

1989-12-29

1988-12-30 Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp

1989-12-29 Publication of PT89371A publication Critical patent/PT89371A/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/38—One sulfur atom
- C07D239/40—One sulfur atom as doubly bound sulfur atom or as unsubstituted mercapto radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Diabetes (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PT89371A 1987-12-31 1988-12-30 Processo de preparacao de 1-aralquil-1,2-di-hidropirimidina-2-tionas e de composicoes farmaceuticas que as contem PT89371A (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US14005287A	1987-12-31	1987-12-31

Publications (1)

Publication Number	Publication Date
PT89371A true PT89371A (pt)	1989-12-29

Family

ID=22489527

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT89371A PT89371A (pt)	1987-12-31	1988-12-30	Processo de preparacao de 1-aralquil-1,2-di-hidropirimidina-2-tionas e de composicoes farmaceuticas que as contem

Country Status (6)

Country	Link
EP (1)	EP0323147A3 (pt)
JP (1)	JPH03501730A (pt)
AU (1)	AU3031889A (pt)
PT (1)	PT89371A (pt)
WO (1)	WO1989006131A1 (pt)
ZA (1)	ZA889670B (pt)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR977401A (fr) *	1948-02-18	1951-04-02	Goodrich Co B F	Perfectionnements relatifs aux 2-mercapto-3-arylpyrimidines et à leur procédé de préparation
GB1155580A (en) *	1965-10-21	1969-06-18	Geigy Ag J R	New Imidazole Derivatives their Production and Use
US3701831A (en) *	1969-11-19	1972-10-31	Merck & Co Inc	Method of inhibiting dopamine beta-hydroxylase
PT78388B (en) *	1983-04-12	1986-09-15	Smithkline Beckman Corp	Dopamine-beta-hydroxylase inhibitors

1988
- 1988-11-16 WO PCT/US1988/004081 patent/WO1989006131A1/en unknown
- 1988-11-16 JP JP89501563A patent/JPH03501730A/ja active Pending
- 1988-11-16 AU AU30318/89A patent/AU3031889A/en not_active Abandoned
- 1988-12-22 EP EP88312194A patent/EP0323147A3/en not_active Withdrawn
- 1988-12-28 ZA ZA889670A patent/ZA889670B/xx unknown
- 1988-12-30 PT PT89371A patent/PT89371A/pt not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO1989006131A1 (en)	1989-07-13
ZA889670B (en)	1989-12-27
EP0323147A2 (en)	1989-07-05
AU3031889A (en)	1989-08-01
EP0323147A3 (en)	1990-08-08
JPH03501730A (ja)	1991-04-18

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Legal Events

Date	Code	Title	Description
1995-01-31	FC3A	Refusal	Effective date: 19940721