[go: up one dir, main page]

PT89793A - Processo de preparacao de derivados de quinolina substituidos e de composicoes farmaceuticas que os contem - Google Patents

Processo de preparacao de derivados de quinolina substituidos e de composicoes farmaceuticas que os contem

Info

Publication number
PT89793A
PT89793A PT89793A PT8979389A PT89793A PT 89793 A PT89793 A PT 89793A PT 89793 A PT89793 A PT 89793A PT 8979389 A PT8979389 A PT 8979389A PT 89793 A PT89793 A PT 89793A
Authority
PT
Portugal
Prior art keywords
pharmaceutical compositions
compositions containing
quinoline derivatives
substituted quinoline
preparing substituted
Prior art date
Application number
PT89793A
Other languages
English (en)
Inventor
Thomas Henry Brown
Robert John Ife
Colin Andrew Leach
Original Assignee
Smithkline Beckman Intercredit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Intercredit filed Critical Smithkline Beckman Intercredit
Publication of PT89793A publication Critical patent/PT89793A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
PT89793A 1988-02-25 1989-02-22 Processo de preparacao de derivados de quinolina substituidos e de composicoes farmaceuticas que os contem PT89793A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888804448A GB8804448D0 (en) 1988-02-25 1988-02-25 Compounds

Publications (1)

Publication Number Publication Date
PT89793A true PT89793A (pt) 1989-10-04

Family

ID=10632380

Family Applications (1)

Application Number Title Priority Date Filing Date
PT89793A PT89793A (pt) 1988-02-25 1989-02-22 Processo de preparacao de derivados de quinolina substituidos e de composicoes farmaceuticas que os contem

Country Status (16)

Country Link
US (1) US4935431A (pt)
EP (1) EP0334491A1 (pt)
JP (1) JPH02503317A (pt)
KR (1) KR900700485A (pt)
CN (1) CN1035508A (pt)
AU (1) AU3181689A (pt)
DK (1) DK528689D0 (pt)
FI (1) FI895047A0 (pt)
GB (1) GB8804448D0 (pt)
HU (1) HU891461D0 (pt)
IL (1) IL89347A0 (pt)
NO (1) NO894228L (pt)
PT (1) PT89793A (pt)
WO (1) WO1989008112A1 (pt)
ZA (1) ZA891440B (pt)
ZW (1) ZW2089A1 (pt)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
NZ233641A (en) * 1989-05-16 1992-07-28 Merrell Dow Pharma Quinoline and thienopyridine derivatives and excitatory amino acid antagonistic pharmaceutical compositions
US5026700A (en) * 1989-05-16 1991-06-25 Merrell Dow Pharmaceuticals Certain quinolines and thienopyridines as excitatory amino acid antagonists
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
IE68593B1 (en) * 1989-12-06 1996-06-26 Sanofi Sa Heterocyclic substituted acylaminothiazoles their preparation and pharmaceutical compositions containing them
GB9010296D0 (en) * 1990-05-08 1990-06-27 Beecham Group Plc Novel compounds
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
KR0169813B1 (ko) * 1995-07-12 1999-01-15 김종인 4-아미노-3-아실나프티리딘 유도체
US6103903A (en) 1998-02-26 2000-08-15 Neurogen Corporation 4-(4-piperidylmethyhlamino) substituted heteroaryl fused pyridines: GABA brain receptor ligands
US6232320B1 (en) * 1998-06-04 2001-05-15 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory compounds
GB0420722D0 (en) 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
PL1828199T3 (pl) * 2004-12-17 2009-10-30 Hoffmann La Roche Pochodne tieno-pirydyny jako alosteryczne wzmacniacze gaba-b
CA2610456A1 (en) 2005-06-02 2006-12-07 F. Hoffmann-La Roche Ag 3-methanesulfonylquinolines as gaba-b enhancers
AR059898A1 (es) 2006-03-15 2008-05-07 Janssen Pharmaceutica Nv Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2
TW200900065A (en) 2007-03-07 2009-01-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
TW200845978A (en) 2007-03-07 2008-12-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
NZ584148A (en) 2007-09-14 2011-05-27 Ortho Mcneil Janssen Pharm 1,3-disubstituted-4-phenyl-1 h-pyridin-2-ones
KR101520086B1 (ko) 2007-09-14 2015-05-14 얀센 파마슈티칼스 인코포레이티드 １´,３´-이치환된-４-페닐-３,４,５,６-테트라히드로-２ｈ,１´ｈ-[１,４´]비피리디닐-２´-온
DK2200985T3 (da) 2007-09-14 2011-10-24 Ortho Mcneil Janssen Pharm 1,3-Disubstituerede 4-(aryl--X-phenyl)-1H-pyridin-2-oner
RU2492170C9 (ru) 2007-11-14 2013-12-27 Орто-Макнейл-Янссен Фармасьютикалз, Инк. Имидазо[1,2-а]пиридиновые производные и их применение в качестве положительных аллостерических модуляторов рецепторов mglur2
CA2705312C (en) * 2007-11-15 2013-06-25 Boehringer Ingelheim International Gmbh Inhibitors of human immunodeficiency virus replication
AU2009289784B2 (en) 2008-09-02 2012-03-22 Addex Pharma S.A. 3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors
CN102186477B (zh) 2008-10-16 2013-07-17 奥梅-杨森制药有限公司 作为代谢型谷氨酸受体调节剂的吲哚和苯并吗啉衍生物
RU2512283C2 (ru) 2008-11-28 2014-04-10 Янссен Фармасьютикалз, Инк. Производные индола и бензоксазина в качестве модуляторов метаботропных глутаматных рецепторов
CN102439008B (zh) 2009-05-12 2015-04-29 杨森制药有限公司 1,2,4-三唑并[4,3-a]吡啶衍生物及其用于治疗或预防神经和精神病症的用途
MY153913A (en) 2009-05-12 2015-04-15 Janssen Pharmaceuticals Inc 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
ES2409006T3 (es) 2009-05-12 2013-06-24 Janssen Pharmaceuticals Inc. Derivados de 1,2,4-triazolo[4,3-a]piridina y su uso como moduladores alostéricos positivos de los receptores mGluR2
CA2815002C (en) 2010-11-08 2019-10-22 Janssen Pharmaceuticals, Inc. 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
CN103298810B (zh) 2010-11-08 2016-03-16 杨森制药公司 1,2,4-三唑并[4,3-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途
CN103261195B (zh) 2010-11-08 2015-09-02 杨森制药公司 1,2,4-三唑并[4,3-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途
JO3368B1 (ar) 2013-06-04 2019-03-13 Janssen Pharmaceutica Nv مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
JO3367B1 (ar) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
IL279202B2 (en) 2014-01-21 2023-09-01 Janssen Pharmaceutica Nv Combinations containing positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic subtype 2 receptor and their use
SG11201605742TA (en) 2014-01-21 2016-08-30 Janssen Pharmaceutica Nv Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2652398A (en) * 1949-11-17 1953-09-15 Endo Products Inc N-substituted-2-amino (methyl) quinolines
US3470186A (en) * 1967-06-02 1969-09-30 American Cyanamid Co Substituted 4-anilino-3-quinolinecarboxylic acids and esters
CA942748A (en) * 1970-09-18 1974-02-26 Venkatachala L. Narayanan 1-aziridinylcarbonyl substituted-3-quinolinecarboxylic acid compounds
US4343804A (en) * 1979-03-26 1982-08-10 A. H. Robins Company, Inc. 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds
EP0126970A3 (en) * 1983-04-27 1985-11-06 Beecham Group Plc Anxiolytic and anti-depressant thienopyridine derivatives
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds

Also Published As

Publication number Publication date
GB8804448D0 (en) 1988-03-23
WO1989008112A1 (en) 1989-09-08
KR900700485A (ko) 1990-08-13
CN1035508A (zh) 1989-09-13
NO894228D0 (no) 1989-10-24
JPH02503317A (ja) 1990-10-11
ZW2089A1 (en) 1989-09-13
HU891461D0 (en) 1990-01-28
DK528689A (da) 1989-10-24
DK528689D0 (da) 1989-10-24
EP0334491A1 (en) 1989-09-27
AU3181689A (en) 1989-09-22
US4935431A (en) 1990-06-19
ZA891440B (en) 1990-10-31
FI895047A0 (fi) 1989-10-24
NO894228L (no) 1989-10-24
IL89347A0 (en) 1989-12-15

Similar Documents

Publication Publication Date Title
PT89793A (pt) Processo de preparacao de derivados de quinolina substituidos e de composicoes farmaceuticas que os contem
PT93241A (pt) Processo de preparacao de derivados de piperidina e de composicoes farmaceuticas que os contem
PT89009A (pt) Processo para a preparacao de novos derivados de fluorocitidina e composicoes farmaceuticas que os contem
PT88993A (pt) Processo de preparacao de compostos azaciclicos e de composicoes farmaceuticas que os contem
PT92497A (pt) Processo para a preparacao de derivados de ureia de dipeptideos inibidores de enzimas, e de composicoes farmaceuticas que os contem
PT87913A (pt) Processo para a preparacao de derivados de benzopirano e de composicoes farmaceuticas que os contem
PT89328A (pt) Processo para a preparacao de novos derivados da adenosina e de composicoes farmaceuticas que os contem
PT87201A (pt) Processo para a preparacao de novos derivados de cefalosporina 3,7-substituida e de composicoes farmaceuticas que os contem
PT91287A (pt) Processo de preparacao de derivados do acido indazol-3-carboxilico e de composicoes farmaceuticas que os contem
PT88203A (pt) Processo para a preparacao de quinolonas e de composicoes farmaceuticas que as contem
PT97437A (pt) Processo de preparacao de derivados de hidrato de carbono e de composicoes farmaceuticas que os contem
PT89405B (pt) Processo para a preparacao de derivados de isoquinolina e de composicoes farmaceuticas que os contem
PT97114A (pt) Processo para a preparacao de derivados de hidantoina e de composicoes farmaceuticas que os contem
PT84681B (pt) Processo para a preparacao de carboxamidas heterociclicas e de composicoes farmaceuticas que as contem
PT83998B (pt) Processo de preparacao de novos derivados azaciclicos e de composicoes farmaceuticas que os contem
PT84187B (pt) Processo para a preparacao de novos derivados da isoquinolina e de composicoes farmaceuticas que os contem
PT89792A (pt) Processo de preparacao de derivados da quinolina substituidos e de composicoes farmaceuticas que os contem
PT89790A (pt) Processo de preparacao de derivados da quinolina substituidos e de composicoes farmaceuticas que os contem
PT89145A (pt) Processo para a preparacao de derivados da manumicina e de composicoes farmaceuticas que os contem
PT90864A (pt) Processo para a preparacao de derivados de cromano e de composicoes farmaceuticas que os contem
PT82319B (pt) Processo de preparacao de derivados de indeno e de naftaleno e de composicoes farmceuticas que os contem
PT88351A (pt) Processo para a preparacao de derivados de isoxazol-beta-carbolina e de composicoes farmaceuticas que os contem
PT91979A (pt) Processo para a preparacao de derivados de cromano e de composicoes farmaceuticas que os contem
PT87115A (pt) Processo para a preparacao de derivados da dihidropiridazinona e de composicoes farmaceuticas que os contem
PT87090A (pt) Processo para a preparacao de derivados de imidazopiridinas e de composicoes farmaceuticas que os contem

Legal Events

Date Code Title Description
FC3A Refusal

Effective date: 19940721