PT88326A - Processo para a preparacao de novos derivados do benzimidazol - Google Patents

Processo para a preparacao de novos derivados do benzimidazol

Info

Publication number: PT88326A
Authority: PT; Portugal
Prior art keywords: benzimidazole derivatives; preparing new; new benzimidazole; preparing; derivatives
Prior art date: 1987-08-25

Application number

PT88326A

Other languages

English (en)

Other versions

PT88326B (pt

Inventor

Helmut Dr Wachtel

Klaus Schollkopf

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-08-25

Filing date

1988-08-24

Publication date

1989-06-30

1988-08-24 Application filed by Schering Ag filed Critical Schering Ag

1989-06-30 Publication of PT88326A publication Critical patent/PT88326A/pt

1995-03-31 Publication of PT88326B publication Critical patent/PT88326B/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicinal Preparation (AREA)

PT88326A 1987-08-25 1988-08-24 Processo para a preparacao de novos derivados do benzimidazol PT88326B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19873728695 DE3728695A1 (de)	1987-08-25	1987-08-25	Neue benzimidazol-derivate

Publications (2)

Publication Number	Publication Date
PT88326A true PT88326A (pt)	1989-06-30
PT88326B PT88326B (pt)	1995-03-31

Family

ID=6334659

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT88326A PT88326B (pt)	1987-08-25	1988-08-24	Processo para a preparacao de novos derivados do benzimidazol

Country Status (17)

Country	Link
US (1)	US4925854A (pt)
EP (1)	EP0304789B1 (pt)
JP (1)	JP2818170B2 (pt)
AT (1)	ATE86982T1 (pt)
AU (1)	AU615939B2 (pt)
CA (1)	CA1330440C (pt)
DD (1)	DD274215A5 (pt)
DE (2)	DE3728695A1 (pt)
DK (1)	DK169701B1 (pt)
ES (1)	ES2054752T3 (pt)
FI (1)	FI99013C (pt)
HU (1)	HU201746B (pt)
IE (1)	IE63283B1 (pt)
IL (1)	IL87561A (pt)
NO (1)	NO170852C (pt)
PT (1)	PT88326B (pt)
ZA (1)	ZA886336B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE914003A1 (en) *	1990-11-20	1992-05-20	Astra Pharma Prod	Biologically Active Amines
US5371102A (en) *	1992-03-11	1994-12-06	University Of Hawaii	Compositions and methods of inhibiting thyroid activity
IL113472A0 (en)	1994-04-29	1995-07-31	Lilly Co Eli	Non-peptidyl tachykinin receptor antogonists
US5565454A (en) *	1995-05-31	1996-10-15	Ergo Science, Incorporated	Method for preventing intervention-associated stenosis and other symptoms associated with stenosis of blood vessels following non-bypass, invasive interventions
TW356468B (en) *	1995-09-15	1999-04-21	Astra Pharma Prod	Benzothiazolone compounds useful as beta2-adrenoreceptor and dopamine DA2 receptor agonists process for preparing same and pharmaceutical compositions containing same
GB9526511D0 (en) *	1995-12-23	1996-02-28	Astra Pharma Prod	Pharmaceutically active compounds
US6974815B2 (en) *	2002-10-11	2005-12-13	Bristol-Myers Squibb Company	Hexahydro-benzimidazolone compounds useful as anti-inflammatory agents
AU2011383263B2 (en)	2011-12-16	2014-09-04	Colgate-Palmolive Company	Color changing compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3813409A (en) *	1972-07-31	1974-05-28	Squibb & Sons Inc	Benzimidazolinone compounds
DE3042481A1 (de) *	1980-11-11	1982-06-16	A. Nattermann & Cie GmbH, 5000 Köln	(omega)-(2-oxo-benzazolinyl)-alkansaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4367337A (en) *	1981-01-05	1983-01-04	The Sherwin-Williams Company	Process for conversion of benzimidazolones to benzotriazoles
US4958026A (en) *	1984-08-15	1990-09-18	Schering Aktiengesllschaft	Novel dopamine derivatives, processes for their preparation, and their use as medicinal agents
US4554287A (en) *	1984-09-12	1985-11-19	Smithkline Beckman Corporation	Antihypertensive 7-[2-(dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones

1987
- 1987-08-25 DE DE19873728695 patent/DE3728695A1/de not_active Withdrawn
1988
- 1988-08-17 ES ES88113339T patent/ES2054752T3/es not_active Expired - Lifetime
- 1988-08-17 AT AT88113339T patent/ATE86982T1/de active
- 1988-08-17 DE DE8888113339T patent/DE3879322D1/de not_active Expired - Lifetime
- 1988-08-17 EP EP88113339A patent/EP0304789B1/de not_active Expired - Lifetime
- 1988-08-22 IE IE255288A patent/IE63283B1/en not_active IP Right Cessation
- 1988-08-23 JP JP63207486A patent/JP2818170B2/ja not_active Expired - Lifetime
- 1988-08-23 DD DD88319141A patent/DD274215A5/de not_active IP Right Cessation
- 1988-08-24 CA CA000575617A patent/CA1330440C/en not_active Expired - Fee Related
- 1988-08-24 NO NO883776A patent/NO170852C/no unknown
- 1988-08-24 HU HU884447A patent/HU201746B/hu not_active IP Right Cessation
- 1988-08-24 PT PT88326A patent/PT88326B/pt not_active IP Right Cessation
- 1988-08-25 FI FI883930A patent/FI99013C/fi not_active IP Right Cessation
- 1988-08-25 DK DK474288A patent/DK169701B1/da not_active IP Right Cessation
- 1988-08-25 IL IL87561A patent/IL87561A/xx not_active IP Right Cessation
- 1988-08-25 US US07/236,383 patent/US4925854A/en not_active Expired - Fee Related
- 1988-08-25 ZA ZA886336A patent/ZA886336B/xx unknown
- 1988-08-25 AU AU21498/88A patent/AU615939B2/en not_active Ceased

Also Published As

Publication number	Publication date
IE882552L (en)	1989-02-25
NO883776D0 (no)	1988-08-24
DE3728695A1 (de)	1989-03-09
IL87561A (en)	1993-02-21
ES2054752T3 (es)	1994-08-16
ZA886336B (en)	1989-04-26
NO170852C (no)	1992-12-16
FI99013B (fi)	1997-06-13
IL87561A0 (en)	1989-01-31
PT88326B (pt)	1995-03-31
HUT49589A (en)	1989-10-30
EP0304789A2 (de)	1989-03-01
DK474288D0 (da)	1988-08-25
NO170852B (no)	1992-09-07
AU615939B2 (en)	1991-10-17
NO883776L (no)	1989-02-27
ATE86982T1 (de)	1993-04-15
EP0304789A3 (en)	1989-10-04
AU2149888A (en)	1989-03-02
DK169701B1 (da)	1995-01-16
DK474288A (da)	1989-02-26
JPS6468359A (en)	1989-03-14
JP2818170B2 (ja)	1998-10-30
CA1330440C (en)	1994-06-28
FI883930A0 (fi)	1988-08-25
EP0304789B1 (de)	1993-03-17
HU201746B (en)	1990-12-28
DE3879322D1 (de)	1993-04-22
DD274215A5 (de)	1989-12-13
US4925854A (en)	1990-05-15
IE63283B1 (en)	1995-04-05
FI883930A (fi)	1989-02-26
FI99013C (fi)	1997-09-25

Publication	Publication Date	Title
ATA62986A (de)	1993-02-15	Verfahren zur herstellung neuer, schwefelhaltiger 5-substituierter benzimidazol-derivate und von deren salzen
HUT48218A (en)	1989-05-29	Process for producing novel, optically active imidazole derivatives
PT83647B (pt)	1989-05-31	Processo para a preparacao de novos derivados de benzimidazole com actividade farmacologica e de composicoes farmaceuticas que os contem
PT88326A (pt)	1989-06-30	Processo para a preparacao de novos derivados do benzimidazol
ATE103603T1 (de)	1994-04-15	Benzimidazolderivate, verfahren zu deren herstellung und deren therapeutische anwendung.
ATA202187A (de)	1993-06-15	Verfahren zur herstellung von 1-(4-aminophenyl)4-methyl-7,8-methylendioxy-3,4-dihydro-5h-2,3benzodiazepin und seine saeureadditionssalze
TR199700206A2 (xx)	1997-10-21	Floralkil- ve floralkoksi ikame edilmi� heterosiklik bradikinin-antagonistleri, bunlar�n imal edilmesine mahsus usul ve bunlar�n kullan�lmalar�.
MX173180B (es)	1994-02-07	Procedimiento para preparar agentes ansioliticos
AT364831B (de)	1981-11-25	Verfahren zur herstellung von neuen 4-hydroxy-2 -benzimidazolinon-derivaten und von deren salzen, razematen und optisch aktiven formen
PT91198A (pt)	1990-02-08	Processo para a preparacao de derivados antiulcera da (alquilditio) quinolina
IT8049304A0 (it)	1980-07-23	Derivati di 1-(4-amminobenzil)-2,3diossopiperazina loro sali con acidi e procedimento per produrli
IT1258844B (it)	1996-02-29	Procedimento per la delignificazione di cellulosa grezza
PT84120B (pt)	1989-07-31	Processo para a preparacao de di-hidropiridinolactois uteis como medicamentos
AT381303B (de)	1986-09-25	Verfahren zur herstellung von neuen, optisch aktiven und racemischen 5-substituierten-4-oxo -pgi1-derivaten sowie von deren salzen
ATE51632T1 (de)	1990-04-15	Lagerstabile konzentrierte waessrige loesungen von melamin-formaldehydkondensaten, verfahren zu deren herstellung, sowie deren verwendung.
DE3780730D1 (de)	1992-09-03	Optisch wirksame beta-aminosaeure derivate und ihre salze und verfahren zu deren herstellung.
ATA139182A (de)	1986-03-15	Verfahren zur herstellung von neuen, optisch aktiven und racemischen 4-oxo-pgi(2)-derivaten sowie von deren salzen
IT8020856A0 (it)	1980-03-21	Amminochetoni eterociclici, loro sali acidi di addizione farmacologicamente compatibili e processo per la loro preparazione.
ATA556180A (de)	1984-01-15	Verfahren zur herstellung von neuen 4-hydroxy-2 -benzimidazolinon-derivaten und von deren salzen, razematen und optisch aktiven formen

Legal Events

Date	Code	Title	Description
1995-03-31	FG3A	Patent granted, date of granting	Effective date: 19940908
1999-07-30	MM3A	Annulment or lapse	Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19990331

Date

Code

Title

Description

1995-03-31

FG3A

Patent granted, date of granting

Effective date: 19940908

1999-07-30

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19990331