PT637248E - Composicao farmaceutica contendo um derivado de ciclosporina - Google Patents

Composicao farmaceutica contendo um derivado de ciclosporina

Info

Publication number: PT637248E
Authority: PT; Portugal
Prior art keywords: pharmaceutical composition; composition containing; cyclosporin derivative; composition; microemulstion
Prior art date: 1992-04-22

Application number

PT93911768T

Other languages

English (en)

Inventor

Friedrich Richter

Armin Meinzer

Jacky Francis Vonderscher

Original Assignee

Novartis Ag

Novartis Erfind Verwalt Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-04-22

Filing date

1993-04-20

Publication date

2002-11-29

1993-04-20 Application filed by Novartis Ag, Novartis Erfind Verwalt Gmbh filed Critical Novartis Ag

2002-11-29 Publication of PT637248E publication Critical patent/PT637248E/pt

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 2
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical class CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
239000000203 mixture Substances 0.000 abstract 2
206010048723 Multiple-drug resistance Diseases 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
229960000074 biopharmaceutical Drugs 0.000 abstract 1
229960001265 ciclosporin Drugs 0.000 abstract 1
239000004530 micro-emulsion Substances 0.000 abstract 1
239000004094 surface-active agent Substances 0.000 abstract 1
208000011580 syndromic disease Diseases 0.000 abstract 1
235000015112 vegetable and seed oil Nutrition 0.000 abstract 1
239000008158 vegetable oil Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Dispersion Chemistry (AREA)
Molecular Biology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Biophysics (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)

PT93911768T 1992-04-22 1993-04-20 Composicao farmaceutica contendo um derivado de ciclosporina PT637248E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB929208712A GB9208712D0 (en)	1992-04-22	1992-04-22	Pharmaceutical compositions containing cyclosporin derivates

Publications (1)

Publication Number	Publication Date
PT637248E true PT637248E (pt)	2002-11-29

Family

ID=10714386

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT93911768T PT637248E (pt)	1992-04-22	1993-04-20	Composicao farmaceutica contendo um derivado de ciclosporina

Country Status (22)

Country	Link
EP (1)	EP0637248B1 (pt)
JP (1)	JP2818298B2 (pt)
KR (2)	KR950701227A (pt)
AT (1)	ATE219940T1 (pt)
AU (1)	AU672793B2 (pt)
CA (1)	CA2132740C (pt)
CY (1)	CY2399B1 (pt)
CZ (1)	CZ287359B6 (pt)
DE (1)	DE69332078T2 (pt)
DK (1)	DK0637248T3 (pt)
ES (1)	ES2179052T3 (pt)
FI (1)	FI111130B (pt)
GB (1)	GB9208712D0 (pt)
HU (1)	HU218279B (pt)
NO (1)	NO315075B1 (pt)
NZ (1)	NZ252681A (pt)
PT (1)	PT637248E (pt)
RU (1)	RU2126263C1 (pt)
SG (1)	SG50692A1 (pt)
SK (1)	SK282745B6 (pt)
UA (1)	UA34454C2 (pt)
WO (1)	WO1993020833A1 (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2222770B (en) *	1988-09-16	1992-07-29	Sandoz Ltd	Pharmaceutical compositions containing cyclosporins
US6007840A (en) *	1988-09-16	1999-12-28	Novartis Ag	Pharmaceutical compositions comprising cyclosporins
US6262022B1 (en)	1992-06-25	2001-07-17	Novartis Ag	Pharmaceutical compositions containing cyclosporin as the active agent
ES2098739T3 (es)	1992-05-13	1997-05-01	Sandoz Ltd	Composiciones oftalmicas conteniendo una cyclosporin.
EP0589843B1 (en)	1992-09-25	2001-11-28	Novartis AG	Pharmaceutical compositions containing cyclosporins
CH686761A5 (de)	1993-05-27	1996-06-28	Sandoz Ag	Galenische Formulierungen.
GB2278780B (en) *	1993-05-27	1998-10-14	Sandoz Ltd	Macrolide formulations
GB2315216B (en) *	1993-10-05	1998-10-14	Ciba Geigy Ag	Microemulsion preconcentrates comprising FK506 or 33-epi-chloro-33-desoxy-ascomycin
ES2177652T3 (es)	1994-11-03	2002-12-16	Novartis Ag	Nuevas formas de preparacion de ciclosporina para la aplicacion oral con composicion simple y alta biodisponibilidad, y procedimiento para su obtencion.
HU215966B (hu) *	1994-11-21	1999-07-28	BIOGAL Gyógyszergyár Rt.	Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
US5766629A (en)	1995-08-25	1998-06-16	Sangstat Medical Corporation	Oral cyclosporin formulations
US5962019A (en) *	1995-08-25	1999-10-05	Sangstat Medical Corporation	Oral cyclosporin formulations
DE19544507B4 (de)	1995-11-29	2007-11-15	Novartis Ag	Cyclosporin enthaltende Präparate
GB9601120D0 (en) *	1996-01-19	1996-03-20	Sandoz Ltd	Organic compounds
CA2294033C (en) *	1997-07-29	2007-01-09	Pharmacia & Upjohn Company	Pharmaceutical composition for acidic lipophilic compounds in a form of a self-emulsifying formulation
CZ297206B6 (cs) *	1997-07-29	2006-10-11	Pharmacia & Upjohn Company	Farmaceutická kompozice a samoemulgující formulace pro lipofilní slouceniny
US6008191A (en) *	1997-09-08	1999-12-28	Panacea Biotec Limited	Pharmaceutical compositions containing cyclosporin
US6346511B1 (en)	1997-09-08	2002-02-12	Panacea Biotec Limited	Pharmaceutical composition comprising cyclosporin
US6187747B1 (en)	1997-09-08	2001-02-13	Panacea Biotech Limited	Pharmaceutical composition comprising cyclosporin
US6294192B1 (en) *	1999-02-26	2001-09-25	Lipocine, Inc.	Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
CZ20033341A3 (cs)	2001-06-21	2004-10-13	Pfizeráproductsáinc	Samoemulgující se kompozice inhibitorů přenosového proteinu cholesterylesteru
US6828301B2 (en)	2002-02-07	2004-12-07	Boehringer Ingelheim International Gmbh	Pharmaceutical compositions for hepatitis C viral protease inhibitors
EP2204167A1 (en) *	2009-01-05	2010-07-07	Azad Pharma AG	Pharmaceutical microemulsion for preventing supramolecular aggregation of amphiphilic molecules
MY154683A (en)	2009-07-07	2015-07-15	Boehringer Ingelheim Int	Pharmaceutical composition for a hepatitis c viral protease inhibitor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FI65914C (fi) *	1978-03-07	1984-08-10	Sandoz Ag	Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a
ATE95193T1 (de) *	1987-06-17	1993-10-15	Sandoz Ag	Cyclosporine und deren benutzung als arzneimittel.
GB2222770B (en) *	1988-09-16	1992-07-29	Sandoz Ltd	Pharmaceutical compositions containing cyclosporins

1992
- 1992-04-22 GB GB929208712A patent/GB9208712D0/en active Pending
1993
- 1993-04-20 HU HU9403055A patent/HU218279B/hu not_active IP Right Cessation
- 1993-04-20 SK SK1272-94A patent/SK282745B6/sk not_active IP Right Cessation
- 1993-04-20 EP EP93911768A patent/EP0637248B1/en not_active Expired - Lifetime
- 1993-04-20 PT PT93911768T patent/PT637248E/pt unknown
- 1993-04-20 DE DE69332078T patent/DE69332078T2/de not_active Expired - Fee Related
- 1993-04-20 AU AU42611/93A patent/AU672793B2/en not_active Ceased
- 1993-04-20 SG SG1996008843A patent/SG50692A1/en unknown
- 1993-04-20 RU RU94046413A patent/RU2126263C1/ru active
- 1993-04-20 DK DK93911768T patent/DK0637248T3/da active
- 1993-04-20 ES ES93911768T patent/ES2179052T3/es not_active Expired - Lifetime
- 1993-04-20 CZ CZ19942617A patent/CZ287359B6/cs not_active IP Right Cessation
- 1993-04-20 WO PCT/EP1993/000955 patent/WO1993020833A1/en active IP Right Grant
- 1993-04-20 NZ NZ252681A patent/NZ252681A/en not_active IP Right Cessation
- 1993-04-20 JP JP5517998A patent/JP2818298B2/ja not_active Expired - Fee Related
- 1993-04-20 CA CA002132740A patent/CA2132740C/en not_active Expired - Fee Related
- 1993-04-20 AT AT93911768T patent/ATE219940T1/de not_active IP Right Cessation
- 1993-04-20 UA UA94105950A patent/UA34454C2/uk unknown
1994
- 1994-10-20 KR KR1019940703729A patent/KR950701227A/ko not_active IP Right Cessation
- 1994-10-21 FI FI944978A patent/FI111130B/fi active
- 1994-10-21 NO NO19943998A patent/NO315075B1/no not_active IP Right Cessation
2000
- 2000-12-08 KR KR10-2000-7013956A patent/KR100414853B1/ko not_active IP Right Cessation
2003
- 2003-12-31 CY CY0300096A patent/CY2399B1/xx unknown

Also Published As

Publication number	Publication date
EP0637248A1 (en)	1995-02-08
DE69332078D1 (de)	2002-08-08
HU218279B (en)	2000-07-28
RU2126263C1 (ru)	1999-02-20
WO1993020833A1 (en)	1993-10-28
NZ252681A (en)	1996-02-27
KR950701227A (ko)	1995-03-23
HUT71580A (en)	1995-12-28
AU672793B2 (en)	1996-10-17
JPH07505872A (ja)	1995-06-29
NO943998L (no)	1994-10-21
NO315075B1 (no)	2003-07-07
CA2132740A1 (en)	1993-10-28
FI944978A0 (fi)	1994-10-21
DK0637248T3 (da)	2002-10-28
CZ287359B6 (en)	2000-11-15
FI111130B (fi)	2003-06-13
FI944978A (fi)	1994-10-21
ES2179052T3 (es)	2003-01-16
DE69332078T2 (de)	2002-12-19
JP2818298B2 (ja)	1998-10-30
HU9403055D0 (en)	1994-12-28
SG50692A1 (en)	1999-05-25
AU4261193A (en)	1993-11-18
CA2132740C (en)	2008-01-15
CZ261794A3 (en)	1995-02-15
NO943998D0 (no)	1994-10-21
SK127294A3 (en)	1995-04-12
UA34454C2 (uk)	2001-03-15
RU94046413A (ru)	1996-11-10
ATE219940T1 (de)	2002-07-15
CY2399B1 (en)	2004-09-10
SK282745B6 (sk)	2002-12-03
GB9208712D0 (en)	1992-06-10
EP0637248B1 (en)	2002-07-03
KR100414853B1 (pt)	2004-01-13

Publication	Publication Date	Title
PT637248E (pt)	2002-11-29	Composicao farmaceutica contendo um derivado de ciclosporina
CA2099782A1 (fr)	1992-07-18	Derive de la 5h-pyrrolo[3,4-b] pyrazine optiquement actif, sa preparation et les compositions pharmaceutiques qui le contiennent
ES2098180A1 (es)	1997-04-16	Una composicion farmaceutica a base de compuestos de la clase de la rapamicina.
MX9204379A (es)	1993-02-01	Microemulsiones de agua en aceite auto-emulsificables, estables, farmaceuticamente aceptables.
AU629669B2 (en)	1992-10-08	Diarylacetylenes, the preparations and use thereof
ATE201980T1 (de)	2001-06-15	Präparate mit lipophilen trägerstoffen
CA2189351A1 (en)	1995-11-23	Narcotic containing aerosol formulation
EP0573423A4 (en)	1994-06-01	Methods and preparations of stable, deodorized oils and pharmaceutical compositions thereof
CA2178632A1 (en)	1995-08-03	Pharmaceutical compositions containing hiv protease inhibitors
EP1238677A3 (en)	2003-01-22	Parenteral fat emulsions comprising edetate as preservative
MXPA97007996A (es)	2004-03-15	Preparado para el transporte de sustancias activas a traves de barreras.
KR950007857A (ko)	1995-04-15	경구투여용 라파마이신 제제
HUP9900365A2 (hu)	1999-05-28	N-Aril-1,2,4-triazolin-5-on-származékok, előállításuk és alkalmazásuk, a vegyületeket hatóanyagként tartalmazó inszekticid, arachnicid és nematocid készítmények
NO175826C (no)	1994-12-14	Mikrobiologisk fremgangsmåte ved fremstilling av agrarkjemisk anvendelige virkestoffer, fremstilte forbindelser, anvendelsen av disse og biologisk rene kulturer av sorangium cellulosum som anvendes i fremgangsmåten
NZ237739A (en)	1993-09-27	Pharmaceutical composition of a complement inhibitor and an immunosuppressant with cyclosporin a-like activity, and its use
DE59205998D1 (de)	1996-05-23	Arzneimittel mit antineoplastischer Wirkung enthaltend als Wirkstoff Octadecyl-[2-(N-methylpiperidino)-ethyl]-phosphat und Verfahren zu dessen Herstellung
KR890015674A (ko)	1989-11-25	수면 시용 농약 입제
CO5640115A2 (es)	2006-05-31	3,4-dihidropirido [1,2-a] pirimidinas sustituidas
AU8079891A (en)	1992-01-23	Bile alcohol and drug containing the same as active ingredient
IT8921516A0 (it)	1989-08-11	Procedimento di microincapsulazione di microorganismi vivi e composizioni farmaceutiche stabili.
FR2655344B1 (fr)	1992-04-03	Derives heterocycliques d'acylaminothiazoles, leur preparation et compositions pharmaceutiques en contenant.
AU2309288A (en)	1990-03-23	Oxime derivatives and herbicides containing same as active ingredients