[go: up one dir, main page]

PT523395E - Regioes sero-reactivas na proteina e1 e e2 de hpv 16 - Google Patents

Regioes sero-reactivas na proteina e1 e e2 de hpv 16

Info

Publication number
PT523395E
PT523395E PT92110430T PT92110430T PT523395E PT 523395 E PT523395 E PT 523395E PT 92110430 T PT92110430 T PT 92110430T PT 92110430 T PT92110430 T PT 92110430T PT 523395 E PT523395 E PT 523395E
Authority
PT
Portugal
Prior art keywords
protein
hpv
mab
regioes
sero
Prior art date
Application number
PT92110430T
Other languages
English (en)
Inventor
Lutz Gissmann
Martin Muller
Original Assignee
Dade Behring Marburg Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dade Behring Marburg Gmbh filed Critical Dade Behring Marburg Gmbh
Publication of PT523395E publication Critical patent/PT523395E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/084Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Detergent Compositions (AREA)
PT92110430T 1991-07-18 1992-06-20 Regioes sero-reactivas na proteina e1 e e2 de hpv 16 PT523395E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4123760A DE4123760C2 (de) 1991-07-18 1991-07-18 Seroreaktive Bereiche auf den HPV 16 Proteinen E1 und E2

Publications (1)

Publication Number Publication Date
PT523395E true PT523395E (pt) 2002-03-28

Family

ID=6436409

Family Applications (1)

Application Number Title Priority Date Filing Date
PT92110430T PT523395E (pt) 1991-07-18 1992-06-20 Regioes sero-reactivas na proteina e1 e e2 de hpv 16

Country Status (10)

Country Link
US (5) US5601973A (pt)
EP (2) EP1136500A3 (pt)
JP (2) JPH0867696A (pt)
AT (1) ATE206434T1 (pt)
AU (1) AU668094B2 (pt)
CA (1) CA2074153C (pt)
DE (2) DE4123760C2 (pt)
DK (1) DK0523395T3 (pt)
ES (1) ES2163394T3 (pt)
PT (1) PT523395E (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000005380A1 (en) * 1998-07-21 2000-02-03 Boehringer Ingelheim (Canada) Ltd. Regions of papilloma virus e1 helicase involved in e1 oligomerization
GB9916363D0 (en) * 1999-07-13 1999-09-15 Univ Bristol Methods of suppressing cell growth
PL365385A1 (en) * 2000-07-21 2005-01-10 Glaxo Group Limited Codon-optimized papilloma virus sequences
GB0017990D0 (en) 2000-07-21 2000-09-13 Glaxo Group Ltd Papilloma virus sequences
ES2724121T3 (es) * 2000-12-08 2019-09-06 Academisch Ziekenhuis Leiden Péptidos largos de 22-45 residuos de aminoácidos que inducen y/o mejoran las respuestas inmunológicas específicas para antígenos
DE10137102A1 (de) * 2001-07-30 2003-02-27 Deutsches Krebsforsch Polyvalente Vakzine gegen durch Papillomaviren verursachte Erkrankungen, Verfahren zu deren Herstellung und deren Verwendung
US7027923B2 (en) * 2003-12-12 2006-04-11 Schlumberger Technology Corporation Method for determining sonde error for an induction or propagation tool with transverse or triaxial arrays
US20090028874A1 (en) * 2003-12-24 2009-01-29 Leiden University Medical Center Synthetic Protein as Tumor-Specific Vaccine
CN101355928B (zh) 2005-04-26 2013-05-22 卫材R&D管理株式会社 用于癌症免疫疗法的组合物和方法
US7972776B2 (en) * 2005-11-15 2011-07-05 Oncohealth Corporation Protein chips for HPV detection
US8968995B2 (en) * 2008-11-12 2015-03-03 Oncohealth Corp. Detection, screening, and diagnosis of HPV-associated cancers
US8859218B2 (en) * 2008-06-13 2014-10-14 Oncohealth Corp. In situ detection of early stages and late stages HPV infection
WO2010129821A1 (en) 2009-05-07 2010-11-11 Oncohealth Corporation Identification of high grade or ≥cin2 for early stages and late stages detection, screening, and diagnosis of human papillomavirus (hpv) and hpv-associated cancers
TW200840869A (en) 2007-01-30 2008-10-16 Transgene Sa Papillomavirus vaccine
ES2445755T3 (es) 2007-11-07 2014-03-05 Celldex Therapeutics, Inc. Anticuerpos que se unen a células dendríticas y epiteliales humanas 205 (DEC-205)
JP5819851B2 (ja) 2010-01-08 2015-11-24 オンコヘルス コーポレーション Hpv関連の癌の治療及びスクリーニングのための細胞に基づいた高処理能力hpv免疫アッセイ
JP6002659B2 (ja) 2010-04-13 2016-10-05 セルデックス・セラピューティクス・インコーポレイテッド ヒトcd27に結合する抗体およびその使用
US20180044429A1 (en) 2015-03-09 2018-02-15 Celldex Therapeutics, Inc. Cd27 agonists
JP7038064B2 (ja) 2016-04-18 2022-03-17 セルデックス セラピューティクス インコーポレイテッド ヒトcd40に結合するアゴニスト抗体およびその使用
MA45491A (fr) 2016-06-27 2019-05-01 Juno Therapeutics Inc Épitopes à restriction cmh-e, molécules de liaison et procédés et utilisations associés
CN110291402B (zh) 2016-06-27 2023-09-01 朱诺治疗学股份有限公司 鉴定肽表位的方法、结合此类表位的分子和相关用途
WO2019164970A1 (en) * 2018-02-20 2019-08-29 Emory University Hpv proteins, antibodies, and uses in managing abnormal epithelial cell growth
AU2019247200A1 (en) 2018-04-05 2020-10-15 Editas Medicine, Inc. Methods of producing cells expressing a recombinant receptor and related compositions
US20210015869A1 (en) 2018-04-05 2021-01-21 Juno Therapeutics, Inc. T cells expressing a recombinant receptor, related polynucleotides and methods
MX2021001523A (es) 2018-08-09 2021-05-27 Juno Therapeutics Inc Procesos para generar células modificadas y composiciones de las mismas.
EA202190693A1 (ru) 2018-09-11 2021-07-27 Джуно Терапьютикс, Инк. Способы анализа масс-спектрометрии композиций модифицированных клеток
CA3136737A1 (en) 2019-05-01 2020-11-05 Juno Therapeutics, Inc. Cells expressing a recombinant receptor from a modified tgfbr2 locus, related polynucleotides and methods
US20240216508A1 (en) 2020-06-26 2024-07-04 Juno Therapeutics Gmbh Engineered t cells conditionally expressing a recombinant receptor, related polynucleotides and methods
CN119529069A (zh) * 2025-01-22 2025-02-28 成都迈科康生物科技有限公司 一种抗hpv16和/或hpv18型e2蛋白的抗体、抗体偶联物及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4554101A (en) * 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
US4777239A (en) * 1986-07-10 1988-10-11 The Board Of Trustees Of The Leland Stanford Junior University Diagnostic peptides of human papilloma virus
US5180806A (en) * 1988-05-16 1993-01-19 The Scripps Research Institute Polypeptides and compositions of human papillomavirus latent proteins, diagnostic systems and methods
JPH063211B2 (ja) * 1989-03-01 1994-01-12 テイエチケー株式会社 直線摺動用ベアリング及び直線摺動用ベアリングの組付け方法
CA2038581A1 (en) * 1990-03-20 1991-09-21 Martin Muller Seroreactive epitopes of human papillomavirus (hpv) 16 proteins
SE9001705D0 (sv) * 1990-05-11 1990-05-11 Medscand Ab Saett foer diagnostik av virusbaerande tumoerer genom immunoassay

Also Published As

Publication number Publication date
EP0523395A3 (pt) 1994-12-14
DK0523395T3 (da) 2002-02-04
EP1136500A3 (de) 2004-03-24
CA2074153C (en) 2003-10-07
AU2042992A (en) 1993-01-21
EP0523395B1 (de) 2001-10-04
AU668094B2 (en) 1996-04-26
JPH0867696A (ja) 1996-03-12
US5601973A (en) 1997-02-11
US20040152074A1 (en) 2004-08-05
EP0523395A2 (de) 1993-01-20
US6221577B1 (en) 2001-04-24
US20010034021A1 (en) 2001-10-25
ES2163394T3 (es) 2002-02-01
US6531127B2 (en) 2003-03-11
ATE206434T1 (de) 2001-10-15
DE4123760C2 (de) 2000-01-20
US20030147915A1 (en) 2003-08-07
JP2003327598A (ja) 2003-11-19
US6723317B2 (en) 2004-04-20
DE4123760A1 (de) 1993-01-21
EP1136500A2 (de) 2001-09-26
DE59209921D1 (de) 2001-11-08
CA2074153A1 (en) 1993-01-19

Similar Documents

Publication Publication Date Title
PT523395E (pt) Regioes sero-reactivas na proteina e1 e e2 de hpv 16
PT992580E (pt) Epitopos para celulas t humanas imunodominantes do virus da hepatite c
PT733069E (pt) Antigenios ctla-8 de primata purificados e reagentes relacionados
ATE177754T1 (de) Fragmente von prion proteinen.
CA2025597A1 (en) Vaccine against lyme disease
NL300272I1 (nl) DNA dat humaan papillomavirus type 18 codeert.
KR910019641A (ko) 사람 유두종 바이러스(hpv) 18의 단백질상의 혈청 반응성 에피토프
ES2129487T3 (es) Peptidos sinteticos, anticuerpos dirigidos contra ellos y su utilizacion.
EP0444856A3 (en) Diagnostic assay for alzheimer's disease
CA2008304A1 (en) Assay for bone alkaline phosphatase
ATE230418T1 (de) Monoklonaler antikörper gegen das humane mx- protein mxa
DE3765822D1 (de) Material fuer affinitaetschromatographie und dessen anwendung zur trennung und reinigung von proteinischen antigenen von bakterien des genus bordetella.
PT623172E (pt) Vacina de virus vaccinia recombinante do virus da doenca de marek
DE3570677D1 (en) Acino-foetal differentiation proteins associated with cancer of the pancreas, antiserum and monoclonal antibodies against these proteins and processes for their preparation
EA200001252A1 (ru) КОМПОЗИЦИЯ РЕКОМБИНАНТНОГО ИНТЕРФЕРОНА-β-1A(IFN-β-1A) ЧЕЛОВЕКА
ATE107165T1 (de) Verwendung von macrolactonen als antiallergica.
DE69428395D1 (de) Neue Aminopeptidase aus Streptomyces
DE69026812D1 (de) Konjugate von "pokeweed" antiviralem protein und monoklonalen antikörpern
ITFI920071A0 (it) Antigeni ricombinanti proteici ad aumentata immunogenicita' contenenti il peptide rappresentato dalla sequenza vogeesndk
SI0717108T1 (en) Recombinant prrs proteins, diagnostic kits and vaccines containing said recombinant proteins
MX9707020A (es) Compuestos y metodos para la deteccion de infeccion por t. cruzi.
ATE89752T1 (de) Neue werkstoffe fuer den knochenersatz und knochen- bzw. prothesenverbund.