PT3723807T - Tratamentos de associação que compreendem a administração de 1h-pirazolo[4,3-b]piridinas - Google Patents

Tratamentos de associação que compreendem a administração de 1h-pirazolo[4,3-b]piridinas

Info

Publication number: PT3723807T
Authority: PT; Portugal
Prior art keywords: pyrazolo; pyridines; administration; association; treatments including
Prior art date: 2017-12-14

Application number

PT188301634T

Other languages

English (en)

Original Assignee

H Lundbeck As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2017-12-14

Filing date

2018-12-12

Publication date

2021-11-26

2018-12-12 Application filed by H Lundbeck As filed Critical H Lundbeck As

2021-11-26 Publication of PT3723807T publication Critical patent/PT3723807T/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PT188301634T 2017-12-14 2018-12-12 Tratamentos de associação que compreendem a administração de 1h-pirazolo[4,3-b]piridinas PT3723807T (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DKPA201700708		2017-12-14

Publications (1)

Publication Number	Publication Date
PT3723807T true PT3723807T (pt)	2021-11-26

Family

ID=64959282

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT188301634T PT3723807T (pt)	2017-12-14	2018-12-12	Tratamentos de associação que compreendem a administração de 1h-pirazolo[4,3-b]piridinas

Country Status (27)

Country	Link
US (1)	US11634416B2 (pt)
EP (1)	EP3723807B1 (pt)
JP (1)	JP7261801B2 (pt)
KR (1)	KR20200099154A (pt)
CN (1)	CN111465410B (pt)
AR (1)	AR113931A1 (pt)
AU (1)	AU2018385453B2 (pt)
BR (1)	BR112019016815A2 (pt)
CA (1)	CA3085201A1 (pt)
CL (1)	CL2020001548A1 (pt)
CO (1)	CO2020007129A2 (pt)
CY (1)	CY1124751T1 (pt)
ES (1)	ES2899868T3 (pt)
HR (1)	HRP20211784T1 (pt)
HU (1)	HUE057202T2 (pt)
IL (1)	IL275290B2 (pt)
LT (1)	LT3723807T (pt)
MX (1)	MX2020006174A (pt)
PL (1)	PL3723807T3 (pt)
PT (1)	PT3723807T (pt)
RS (1)	RS62551B1 (pt)
RU (1)	RU2020118913A (pt)
SG (1)	SG11202005361RA (pt)
SI (1)	SI3723807T1 (pt)
SM (1)	SMT202100655T1 (pt)
WO (1)	WO2019115566A1 (pt)
ZA (1)	ZA202003514B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US10034861B2 (en)	2016-07-04	2018-07-31	H. Lundbeck A/S	1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors
AR113926A1 (es)	2017-12-14	2020-07-01	H Lundbeck As	Derivados de 1h-pirazolo[4,3-b]piridinas
PL3723807T3 (pl)	2017-12-14	2022-01-24	H. Lundbeck A/S	Leczenie skojarzone obejmujące podawanie 1h-pirazolo[4,3-b]pirydyn
US11535611B2 (en)	2017-12-20	2022-12-27	H. Lundbeck A/S	Pyrazolo[3,4-B]pyridines and imidazo[1,5-B]pyridazines as PDE1 inhibitors

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JP6100883B2 (ja)	2012-03-19	2017-03-22	アビデセラピューティクス，インク．	カルバマート化合物、及びその製造並びに使用
TW201533043A (zh)	2013-04-18	2015-09-01	Lundbeck & Co As H	作爲ｌｒｒｋ２抑制劑的芳基吡咯并吡啶衍生化合物
UA116023C2 (uk)	2013-07-08	2018-01-25	Ф. Хоффманн-Ля Рош Аг	Етинільні похідні як антагоністи метаботропного глутаматного рецептора
KR20160115936A (ko)	2014-02-19	2016-10-06	하. 룬드벡 아크티에셀스카브	알츠하이머병의 치료를 위한 bace1 저해제로서의 2-아미노-3,5,5-트리플루오로-3,4,5,6-테트라하이드로피리딘
TWI599358B (zh)	2014-09-16	2017-09-21	美國禮來大藥廠	組合療法
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CR20170187A (es)	2014-11-10	2018-02-01	H Lundbeck As	2-Amino-3,5-difluoro-6-metil-6-fenil-3,4,5,6-tetrahidropiridinas en calidad de inhibidores de BACE1 para el tratamiento de la enfermedad de Alzheimer
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JO3711B1 (ar)	2015-07-13	2021-01-31	H Lundbeck As	أجسام مضادة محددة لبروتين تاو وطرق استعمالها
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AU2016305275A1 (en)	2015-08-12	2018-02-08	H. Lundbeck A/S	2-amino-3-fluoro-3-(fluoromethyl)-6-methyl-6-phenyl-3,4,5,6-tetrahydropyridins as bace1 inhibitors
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US10034861B2 (en)	2016-07-04	2018-07-31	H. Lundbeck A/S	1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors
JOP20190126A1 (ar)	2016-12-22	2019-05-28	H Lundbeck As	بيرازولو [3، 4-b] بيريدينات وإيميدازو [1، 5-b] بيريدازينات على هيئة مثبطات PDE1
AR113926A1 (es) *	2017-12-14	2020-07-01	H Lundbeck As	Derivados de 1h-pirazolo[4,3-b]piridinas
PL3723807T3 (pl)	2017-12-14	2022-01-24	H. Lundbeck A/S	Leczenie skojarzone obejmujące podawanie 1h-pirazolo[4,3-b]pirydyn
TW201927784A (zh) *	2017-12-20	2019-07-16	丹麥商Ｈ朗德貝克公司	作為pde1抑制劑之大環
US10766893B2 (en)	2017-12-20	2020-09-08	H. Lundbeck A/S	1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors
US11535611B2 (en) *	2017-12-20	2022-12-27	H. Lundbeck A/S	Pyrazolo[3,4-B]pyridines and imidazo[1,5-B]pyridazines as PDE1 inhibitors

2018
- 2018-12-12 PL PL18830163T patent/PL3723807T3/pl unknown
- 2018-12-12 LT LTEPPCT/EP2018/084432T patent/LT3723807T/lt unknown
- 2018-12-12 SG SG11202005361RA patent/SG11202005361RA/en unknown
- 2018-12-12 CN CN201880079962.7A patent/CN111465410B/zh active Active
- 2018-12-12 RS RS20211372A patent/RS62551B1/sr unknown
- 2018-12-12 RU RU2020118913A patent/RU2020118913A/ru unknown
- 2018-12-12 SM SM20210655T patent/SMT202100655T1/it unknown
- 2018-12-12 WO PCT/EP2018/084432 patent/WO2019115566A1/en active Application Filing
- 2018-12-12 MX MX2020006174A patent/MX2020006174A/es unknown
- 2018-12-12 SI SI201830453T patent/SI3723807T1/sl unknown
- 2018-12-12 HR HRP20211784TT patent/HRP20211784T1/hr unknown
- 2018-12-12 ES ES18830163T patent/ES2899868T3/es active Active
- 2018-12-12 HU HUE18830163A patent/HUE057202T2/hu unknown
- 2018-12-12 KR KR1020207019016A patent/KR20200099154A/ko not_active Ceased
- 2018-12-12 AU AU2018385453A patent/AU2018385453B2/en not_active Expired - Fee Related
- 2018-12-12 EP EP18830163.4A patent/EP3723807B1/en active Active
- 2018-12-12 JP JP2020531953A patent/JP7261801B2/ja active Active
- 2018-12-12 US US16/772,561 patent/US11634416B2/en active Active
- 2018-12-12 PT PT188301634T patent/PT3723807T/pt unknown
- 2018-12-12 BR BR112019016815A patent/BR112019016815A2/pt unknown
- 2018-12-12 CA CA3085201A patent/CA3085201A1/en active Pending
- 2018-12-13 AR ARP180103639A patent/AR113931A1/es unknown
2020
- 2020-06-10 CL CL2020001548A patent/CL2020001548A1/es unknown
- 2020-06-11 ZA ZA2020/03514A patent/ZA202003514B/en unknown
- 2020-06-11 IL IL275290A patent/IL275290B2/en unknown
- 2020-06-11 CO CONC2020/0007129A patent/CO2020007129A2/es unknown
2021
- 2021-11-25 CY CY20211101025T patent/CY1124751T1/el unknown

Also Published As

Publication number	Publication date
SMT202100655T1 (it)	2022-01-10
RU2020118913A (ru)	2022-01-14
SI3723807T1 (sl)	2022-01-31
CN111465410B (zh)	2022-10-25
IL275290B2 (en)	2023-06-01
AU2018385453B2 (en)	2024-02-08
HUE057202T2 (hu)	2022-04-28
LT3723807T (lt)	2021-12-10
CY1124751T1 (el)	2022-07-22
SG11202005361RA (en)	2020-07-29
US11634416B2 (en)	2023-04-25
KR20200099154A (ko)	2020-08-21
CA3085201A1 (en)	2019-06-20
EP3723807B1 (en)	2021-10-20
BR112019016815A2 (pt)	2020-04-07
HRP20211784T1 (hr)	2022-02-18
MX2020006174A (es)	2022-09-27
EP3723807A1 (en)	2020-10-21
AR113931A1 (es)	2020-07-01
JP7261801B2 (ja)	2023-04-20
IL275290A (en)	2020-07-30
US20200385381A1 (en)	2020-12-10
ZA202003514B (en)	2022-12-21
CO2020007129A2 (es)	2020-06-19
PL3723807T3 (pl)	2022-01-24
CL2020001548A1 (es)	2020-09-25
RS62551B1 (sr)	2021-12-31
JP2021506775A (ja)	2021-02-22
CN111465410A (zh)	2020-07-28
ES2899868T3 (es)	2022-03-15
AU2018385453A1 (en)	2020-07-02
WO2019115566A1 (en)	2019-06-20

Publication	Publication Date	Title
DK3846904T3 (da)	2023-08-21	5-morpholin-4-yl-pyrazolo[4,3-b]pyridinderivater
HUE051067T2 (hu)	2021-01-28	N-szulfonilezett pirazolo[3,4-b]piridin-6-karboxamidok és alkalmazási módszereik
HK1244804A1 (zh)	2018-08-17	4h-吡咯並[3，2-c]吡啶-4-酮衍生物
EP3452481A4 (en)	2020-02-26	IMIDAZO [1,2-B] SUBSTITUTED PYRIDAZINES, IMIDAZO [1,5-B] SUBSTITUTED PYRIDAZINES, RELATED COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL CONDITIONS
IL253595A0 (en)	2017-09-28	Salt of a pyrimido[6,1-a]isoquinolin-4-one compound
EP3494213A4 (en)	2020-01-08	MODEL FOR BLOOD BRAIN CABINETS AND METHOD FOR THE PRODUCTION AND USE THEREOF
HRP20190013T1 (hr)	2019-02-22	Derivati 1,2-dihidro-3h-pirolo[1,2 -c]imidazol-3-ona i njihova uporaba kao antibakterijska sredstva
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