PT2380985E - Células que expressam a vitamina k epóxido reductase e sua utilização - Google Patents

Células que expressam a vitamina k epóxido reductase e sua utilização Download PDF

Info

Publication number: PT2380985E
Authority: PT; Portugal
Prior art keywords: cells expressing; epoxide reductase; warfarin; increased; expressing vitamin
Prior art date: 2003-09-23

Application number

PT111569794T

Other languages

English (en)

Inventor

Darrel W Stafford

Tao Li

Original Assignee

Univ North Carolina

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-09-23

Filing date

2004-09-23

Publication date

2014-03-26

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34393028&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2380985(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-09-23 Application filed by Univ North Carolina filed Critical Univ North Carolina

2014-03-26 Publication of PT2380985E publication Critical patent/PT2380985E/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes

Landscapes

Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Microbiology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Analytical Chemistry (AREA)
Virology (AREA)
Plant Pathology (AREA)
Pathology (AREA)
Medicinal Chemistry (AREA)
Immunology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)

PT111569794T 2003-09-23 2004-09-23 Células que expressam a vitamina k epóxido reductase e sua utilização PT2380985E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US50552703P	2003-09-23	2003-09-23

Publications (1)

Publication Number	Publication Date
PT2380985E true PT2380985E (pt)	2014-03-26

Family

ID=34393028

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT111569794T PT2380985E (pt)	2003-09-23	2004-09-23	Células que expressam a vitamina k epóxido reductase e sua utilização

Country Status (13)

Country	Link
US (6)	US7687233B2 (pt)
EP (4)	EP2336360A1 (pt)
JP (4)	JP2007506433A (pt)
AT (1)	ATE455174T1 (pt)
AU (2)	AU2004275828B2 (pt)
CA (1)	CA2539434C (pt)
DE (1)	DE602004025157D1 (pt)
DK (2)	DK1842920T4 (pt)
ES (2)	ES2339710T5 (pt)
HK (1)	HK1093223A1 (pt)
PL (1)	PL1842920T5 (pt)
PT (1)	PT2380985E (pt)
WO (1)	WO2005030039A2 (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
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PT2380985E (pt)	2003-09-23	2014-03-26	Univ North Carolina	Células que expressam a vitamina k epóxido reductase e sua utilização
GB0324044D0 (en)	2003-10-14	2003-11-19	Astrazeneca Ab	Protein
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US7445896B2 (en)	2004-10-18	2008-11-04	University Of Washington	Methods and compositions for detecting VKORC1 single nucleotide polymorphisms
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CA2599284A1 (en) *	2005-02-28	2006-08-31	Baxter International Inc.	Recombinant co-expression of vitamin k epoxide reductase subunit 1 to improve vitamin k dependent protein expression
CA2601574C (en)	2005-03-15	2014-12-02	University Of North Carolina At Chapel Hill	Methods and compositions for producing active vitamin k-dependent proteins
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EP2655607A4 (en)	2010-12-21	2014-05-14	Univ North Carolina	METHOD AND COMPOSITIONS FOR PRODUCING ACTIVE VITAMIN K-DEPENDENT PROTEINS
JP2012139232A (ja) *	2012-03-15	2012-07-26	Univ Of North Carolina At Chapel Hill	活性ビタミンｋ依存性タンパク質を生産するための方法及び組成物
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CA2601574C (en)	2005-03-15	2014-12-02	University Of North Carolina At Chapel Hill	Methods and compositions for producing active vitamin k-dependent proteins
JP5461008B2 (ja)	2005-04-13	2014-04-02	アストラゼネカアクチボラグ	ベクター
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2004
- 2004-09-23 PT PT111569794T patent/PT2380985E/pt unknown
- 2004-09-23 PL PL07109353T patent/PL1842920T5/pl unknown
- 2004-09-23 ES ES07109353.8T patent/ES2339710T5/es not_active Expired - Lifetime
- 2004-09-23 CA CA2539434A patent/CA2539434C/en not_active Expired - Lifetime
- 2004-09-23 US US10/573,131 patent/US7687233B2/en not_active Expired - Fee Related
- 2004-09-23 AU AU2004275828A patent/AU2004275828B2/en not_active Expired
- 2004-09-23 ES ES11156979.4T patent/ES2453895T3/es not_active Expired - Lifetime
- 2004-09-23 DK DK07109353.8T patent/DK1842920T4/da active
- 2004-09-23 EP EP10178665A patent/EP2336360A1/en not_active Withdrawn
- 2004-09-23 DK DK11156979.4T patent/DK2380985T3/en active
- 2004-09-23 EP EP07109353.8A patent/EP1842920B2/en not_active Expired - Lifetime
- 2004-09-23 EP EP11156979.4A patent/EP2380985B1/en not_active Expired - Lifetime
- 2004-09-23 EP EP04789039.7A patent/EP1670947B1/en not_active Expired - Lifetime
- 2004-09-23 WO PCT/US2004/031481 patent/WO2005030039A2/en active Application Filing
- 2004-09-23 AT AT07109353T patent/ATE455174T1/de not_active IP Right Cessation
- 2004-09-23 DE DE602004025157T patent/DE602004025157D1/de not_active Expired - Lifetime
- 2004-09-23 JP JP2006528251A patent/JP2007506433A/ja not_active Withdrawn
2006
- 2006-09-06 US US11/516,229 patent/US7524665B2/en not_active Expired - Lifetime
- 2006-12-20 HK HK06114003.0A patent/HK1093223A1/xx not_active IP Right Cessation
2007
- 2007-01-30 US US11/699,930 patent/US7482141B2/en not_active Expired - Lifetime
- 2007-10-26 US US11/924,707 patent/US8097410B2/en not_active Expired - Fee Related
2009
- 2009-01-28 US US12/361,053 patent/US7858318B2/en not_active Expired - Fee Related
2010
- 2010-07-02 JP JP2010151738A patent/JP5094920B2/ja not_active Expired - Fee Related
- 2010-07-26 AU AU2010203318A patent/AU2010203318B2/en not_active Ceased
- 2010-12-17 US US12/971,574 patent/US8426128B2/en not_active Expired - Fee Related
2012
- 2012-03-12 JP JP2012054537A patent/JP5840539B2/ja not_active Expired - Lifetime
2015
- 2015-05-07 JP JP2015094928A patent/JP2015180205A/ja active Pending

Also Published As

Publication number	Publication date
PL1842920T3 (pl)	2010-06-30
US7687233B2 (en)	2010-03-30
EP1842920B1 (en)	2010-01-13
EP1670947B1 (en)	2015-04-01
JP5094920B2 (ja)	2012-12-12
DE602004025157D1 (de)	2010-03-04
ES2339710T3 (es)	2010-05-24
AU2004275828B2 (en)	2010-04-29
US8426128B2 (en)	2013-04-23
ATE455174T1 (de)	2010-01-15
EP2380985A1 (en)	2011-10-26
AU2010203318A1 (en)	2010-08-12
DK1842920T3 (da)	2010-05-03
CA2539434A1 (en)	2005-04-07
JP2015180205A (ja)	2015-10-15
US20070009950A1 (en)	2007-01-11
JP5840539B2 (ja)	2016-01-06
US7858318B2 (en)	2010-12-28
JP2010268803A (ja)	2010-12-02
CA2539434C (en)	2014-03-18
EP2380985B1 (en)	2014-01-01
ES2339710T5 (es)	2017-10-05
US7482141B2 (en)	2009-01-27
US7524665B2 (en)	2009-04-28
WO2005030039A2 (en)	2005-04-07
DK2380985T3 (en)	2014-03-17
US8097410B2 (en)	2012-01-17
JP2012161315A (ja)	2012-08-30
US20090215061A1 (en)	2009-08-27
HK1093223A1 (en)	2007-02-23
US20110124000A1 (en)	2011-05-26
EP1670947A4 (en)	2008-11-05
PL1842920T5 (pl)	2018-04-30
EP1842920A1 (en)	2007-10-10
JP2007506433A (ja)	2007-03-22
ES2453895T3 (es)	2014-04-08
US20090215045A1 (en)	2009-08-27
EP1842920B2 (en)	2017-06-21
WO2005030039A3 (en)	2005-07-21
DK1842920T4 (da)	2017-08-21
AU2010203318B2 (en)	2012-07-12
EP1670947A2 (en)	2006-06-21
US20060240440A1 (en)	2006-10-26
EP2336360A1 (en)	2011-06-22
US20070190614A1 (en)	2007-08-16
AU2004275828A1 (en)	2005-04-07

Publication	Publication Date	Title
PT2380985E (pt)	2014-03-26	Células que expressam a vitamina k epóxido reductase e sua utilização
ATE330038T1 (de)	2006-07-15	Nukleinsäure-biosensor
IL172910A0 (en)	2006-06-11	Method for detection of alkylated cytosine in dna
EP1985715A3 (en)	2008-12-31	ESR1 and cervical cancer
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