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PT2379734T - Método para o controlo da massa molecular do polissacárido do serotipo 19a de streptococcus pneumoniae - Google Patents

Método para o controlo da massa molecular do polissacárido do serotipo 19a de streptococcus pneumoniae

Info

Publication number
PT2379734T
PT2379734T PT97958623T PT09795862T PT2379734T PT 2379734 T PT2379734 T PT 2379734T PT 97958623 T PT97958623 T PT 97958623T PT 09795862 T PT09795862 T PT 09795862T PT 2379734 T PT2379734 T PT 2379734T
Authority
PT
Portugal
Prior art keywords
molecular weight
streptococcus pneumoniae
pneumoniae serotype
polysaccharide molecular
controlling
Prior art date
Application number
PT97958623T
Other languages
English (en)
Inventor
Heather Crinean Jean
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of PT2379734T publication Critical patent/PT2379734T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
PT97958623T 2008-12-18 2009-12-17 Método para o controlo da massa molecular do polissacárido do serotipo 19a de streptococcus pneumoniae PT2379734T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13856308P 2008-12-18 2008-12-18

Publications (1)

Publication Number Publication Date
PT2379734T true PT2379734T (pt) 2018-04-27

Family

ID=42266457

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97958623T PT2379734T (pt) 2008-12-18 2009-12-17 Método para o controlo da massa molecular do polissacárido do serotipo 19a de streptococcus pneumoniae

Country Status (19)

Country Link
US (1) US8795689B2 (pt)
EP (1) EP2379734B1 (pt)
JP (1) JP5843612B2 (pt)
KR (2) KR20110091546A (pt)
CN (1) CN102257155B (pt)
AU (1) AU2009335826B2 (pt)
BR (1) BRPI0922981A8 (pt)
CA (1) CA2743710C (pt)
DK (1) DK2379734T3 (pt)
ES (1) ES2666698T3 (pt)
HK (1) HK1163750A1 (pt)
HU (1) HUE037465T2 (pt)
IL (1) IL213169A (pt)
MX (1) MX2011006432A (pt)
PL (1) PL2379734T3 (pt)
PT (1) PT2379734T (pt)
RU (1) RU2511404C2 (pt)
SI (1) SI2379734T1 (pt)
WO (1) WO2010080486A2 (pt)

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BRPI0923165A8 (pt) * 2008-12-18 2017-09-12 Wyeth Llc método para a produção de uma solução contendo polissacarídeos capsulares de streptococcus pneumoniae isolados de alto peso molecular, bem como solução contendo os referidos polissacarídeos
WO2010125480A1 (en) 2009-04-30 2010-11-04 Coley Pharmaceutical Group, Inc. Pneumococcal vaccine and uses thereof
WO2013088448A1 (en) * 2011-12-15 2013-06-20 Serum Institute Of India Ltd. A novel process of cultivating bacteria for yield improvement of capsular polyoses
AU2013313794B2 (en) 2012-09-07 2016-10-20 Sk Bioscience Co., Ltd. Production method for capsular polysaccharide having pneumococcal serotype
IL317054A (en) 2016-12-30 2025-01-01 Vaxcyte Inc Polypeptide-antigen conjugates with unnatural amino acids
US11951165B2 (en) 2016-12-30 2024-04-09 Vaxcyte, Inc. Conjugated vaccine carrier proteins
CN116870144A (zh) 2017-01-31 2023-10-13 默沙东有限责任公司 制备多糖-蛋白缀合物的方法
MX2019009867A (es) 2017-02-24 2019-10-02 Merck Sharp & Dohme Inmunogenicidad mejorada de conjugados de polisacarido-proteina de streptococcus pneumoniae.
US10729763B2 (en) 2017-06-10 2020-08-04 Inventprise, Llc Mixtures of polysaccharide-protein pegylated compounds
CN111132691A (zh) 2017-06-10 2020-05-08 创赏有限公司 提供改善的免疫原性和亲合力的具有二价或多价缀合物多糖的多价缀合物疫苗
BR112020004502A8 (pt) * 2017-09-07 2022-11-01 Merck Sharp & Dohme Polissacarídeos pneumocócicos e uso dos mesmos em conjugados imunogênicos polissacarídeo-proteína carreadora
BR112020004471A8 (pt) 2017-09-07 2022-11-01 Merck Sharp & Dohme Polissacarídeos pneumocócicos e uso dos mesmos em conjugados imunogênicos polissacarídeo-proteína carreadora
MX2020005779A (es) 2017-12-06 2020-10-28 Merck Sharp & Dohme Composiciones que comprenden conjugados de polisacarido de streptococcus pneumoniae con proteina y metodos de uso de estos.
EP3782642A4 (en) * 2018-04-18 2022-04-13 SK Bioscience Co., Ltd. Streptococcus pneumoniae capsular polysaccharides and immunogenic conjugate thereof
KR20210005161A (ko) 2018-04-30 2021-01-13 머크 샤프 앤드 돔 코포레이션 리오스피어로부터 스트렙토코쿠스 뉴모니아에 피막 폴리사카라이드 담체 단백질 접합체를 제조하는 방법
US20210252125A1 (en) 2018-04-30 2021-08-19 Merck Sharp & Dohme Corp. Methods for producing streptococcus pneumoniae capsular polysaccharide carrier protein conjugates
WO2019212844A1 (en) 2018-04-30 2019-11-07 Merck Sharp & Dohme Corp. Methods for providing a homogenous solution of lyophilized mutant diptheria toxin in dimethylsulfoxide
KR20240169145A (ko) 2018-12-19 2024-12-02 머크 샤프 앤드 돔 엘엘씨 스트렙토코쿠스 뉴모니아에 폴리사카라이드-단백질 접합체를 포함하는 조성물 및 그의 사용 방법
CA3191005A1 (en) 2020-08-10 2022-02-17 Inventprise, Inc. Multivalent pneumococcal glycoconjugate vaccines containing emerging serotype 24f

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CA1115210A (en) 1977-11-28 1981-12-29 Dennis J. Carlo Pneumococcal vaccine
US4221906A (en) * 1979-03-19 1980-09-09 American Cyanamid Company Stabilization of pneumococcal polysaccharides
US4242501A (en) 1979-08-08 1980-12-30 American Cyanamid Company Purification of pneumococcal capsular polysaccharides
FR2495939B1 (fr) 1980-12-11 1985-10-11 Merieux Inst Procede de purification de polyosides de streptococcus pneumoniae et vaccin a base de polyosides ainsi purifies
BE889979A (fr) 1981-08-14 1982-02-15 Smith Kline Rit Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation
US4686102A (en) * 1984-04-12 1987-08-11 American Cyanamid Company Multivalent pneumococcal vaccine and preparation thereof
CA2059692C (en) * 1991-01-28 2004-11-16 Peter J. Kniskern Pneumoccoccal polysaccharide conjugate vaccine
CA2059693C (en) 1991-01-28 2003-08-19 Peter J. Kniskern Polysaccharide antigens from streptococcus pneumoniae
US5314822A (en) * 1992-10-15 1994-05-24 Merck & Co., Inc. Method of clonal growth of Streptococcus pneumoniae
US5714354A (en) * 1995-06-06 1998-02-03 American Home Products Corporation Alcohol-free pneumococcal polysaccharide purification process
US6146902A (en) * 1998-12-29 2000-11-14 Aventis Pasteur, Inc. Purification of polysaccharide-protein conjugate vaccines by ultrafiltration with ammonium sulfate solutions
DK1268844T3 (da) * 2000-03-16 2009-11-16 Philadelphia Children Hospital Modulering af fremstilling af pneumococcus kapselformigt polysaccharid
US6743610B2 (en) * 2001-03-30 2004-06-01 The University Of Chicago Method to produce succinic acid from raw hydrolysates
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PT1664319E (pt) * 2003-09-11 2010-06-17 Staat Der Nederlanden Vert Doo Processo para a produção de um polissacarídeo capsular para ser usado em vacinas de conjugados
EP3466982B1 (en) 2005-04-08 2020-06-17 Wyeth LLC Separation of contaminants from streptococcus pneumoniae polysaccharide by ph manipulation
US7955605B2 (en) 2005-04-08 2011-06-07 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
CN113198013B (zh) * 2005-04-08 2024-02-20 惠氏有限责任公司 多价肺炎球菌多糖－蛋白质缀合物组合物
US20070184072A1 (en) * 2005-04-08 2007-08-09 Wyeth Multivalent pneumococcal polysaccharide-protein conjugate composition
US7709001B2 (en) 2005-04-08 2010-05-04 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
GB0522303D0 (en) * 2005-11-01 2005-12-07 Chiron Srl Culture method
BR122019021950B8 (pt) 2006-10-10 2021-07-27 Wyeth Corp métodos para a redução ou remoção de impurezas protéicas de um lisado ou centrado celular de streptococcus pneumoniae compreendendo polissacarídeos sorotipo 3
US7860500B2 (en) * 2006-10-27 2010-12-28 Motorola, Inc. Method and apparatus for determining appropriate channels for communication
ES2922132T3 (es) * 2007-03-23 2022-09-08 Wyeth Llc Procedimiento abreviado de purificación para la producción de polisacáridos capsulares de Streptococcus pneumoniae
BRPI0923165A8 (pt) * 2008-12-18 2017-09-12 Wyeth Llc método para a produção de uma solução contendo polissacarídeos capsulares de streptococcus pneumoniae isolados de alto peso molecular, bem como solução contendo os referidos polissacarídeos

Also Published As

Publication number Publication date
US20100158953A1 (en) 2010-06-24
CA2743710A1 (en) 2010-07-15
CN102257155A (zh) 2011-11-23
BRPI0922981A2 (pt) 2015-08-25
PL2379734T3 (pl) 2018-08-31
KR20130136011A (ko) 2013-12-11
AU2009335826B2 (en) 2013-10-31
WO2010080486A3 (en) 2010-11-04
DK2379734T3 (en) 2018-04-23
WO2010080486A2 (en) 2010-07-15
MX2011006432A (es) 2011-09-29
US8795689B2 (en) 2014-08-05
AU2009335826A1 (en) 2010-07-15
IL213169A0 (en) 2011-07-31
CA2743710C (en) 2017-01-24
BRPI0922981A8 (pt) 2019-11-26
CN102257155B (zh) 2016-03-02
KR20110091546A (ko) 2011-08-11
ES2666698T3 (es) 2018-05-07
HK1163750A1 (zh) 2012-09-14
KR101593770B1 (ko) 2016-02-15
RU2011128564A (ru) 2013-01-27
HUE037465T2 (hu) 2018-09-28
SI2379734T1 (en) 2018-05-31
RU2511404C2 (ru) 2014-04-10
IL213169A (en) 2015-02-26
EP2379734A2 (en) 2011-10-26
EP2379734B1 (en) 2018-03-21
JP5843612B2 (ja) 2016-01-13
JP2012512660A (ja) 2012-06-07

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