PT1277746E - Novos derivados de n-benzilpiperazina, processo para a sua preparacao e as composicoes farmaceuticas que os contem - Google Patents

Novos derivados de n-benzilpiperazina, processo para a sua preparacao e as composicoes farmaceuticas que os contem

Info

Publication number: PT1277746E
Authority: PT; Portugal
Prior art keywords: contain; preparation; new; pharmaceutical compositions; benzylpiperazine derivatives
Prior art date: 2001-07-16

Application number

PT02291784T

Other languages

English (en)

Inventor

Serge Labidalle

Tillement Jean-Paul

Testa Bernard

Cecchelli Romeo

Le Ridant Alain

Harpey Catherine

Spedding Michael

Schenker Esther

Original Assignee

Servier Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-07-16

Filing date

2002-07-16

Publication date

2005-07-29

2002-07-16 Application filed by Servier Lab filed Critical Servier Lab

2005-07-29 Publication of PT1277746E publication Critical patent/PT1277746E/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Diabetes (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Surgery (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)

PT02291784T 2001-07-16 2002-07-16 Novos derivados de n-benzilpiperazina, processo para a sua preparacao e as composicoes farmaceuticas que os contem PT1277746E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR0109454A FR2827284B1 (fr)	2001-07-16	2001-07-16	Nouveaux derives de n-benzylpiperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number	Publication Date
PT1277746E true PT1277746E (pt)	2005-07-29

Family

ID=8865549

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT02291784T PT1277746E (pt)	2001-07-16	2002-07-16	Novos derivados de n-benzilpiperazina, processo para a sua preparacao e as composicoes farmaceuticas que os contem

Country Status (23)

Country	Link
US (1)	US6686360B2 (pt)
EP (1)	EP1277746B1 (pt)
JP (1)	JP2003096057A (pt)
KR (1)	KR100498867B1 (pt)
CN (1)	CN1397554A (pt)
AR (1)	AR034779A1 (pt)
AT (1)	ATE295358T1 (pt)
AU (1)	AU2002300150B2 (pt)
BR (1)	BR0202686A (pt)
CA (1)	CA2394010A1 (pt)
DE (1)	DE60204083T2 (pt)
DK (1)	DK1277746T3 (pt)
EA (1)	EA005165B1 (pt)
ES (1)	ES2241973T3 (pt)
FR (1)	FR2827284B1 (pt)
HU (1)	HUP0202293A3 (pt)
MX (1)	MXPA02006900A (pt)
NO (1)	NO20023409L (pt)
NZ (1)	NZ520173A (pt)
PL (1)	PL355066A1 (pt)
PT (1)	PT1277746E (pt)
SI (1)	SI1277746T1 (pt)
ZA (1)	ZA200205666B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8174436B2 (en)	2002-07-08	2012-05-08	American Underwater Products, Inc.	Dive computer with global positioning system receiver
US9443039B2 (en)	2002-07-08	2016-09-13	Pelagic Pressure Systems Corp.	Systems and methods for dive computers with remote upload capabilities
WO2004101529A1 (ja) *	2003-05-19	2004-11-25	Ono Pharmaceutical Co., Ltd.	含窒素複素環化合物およびその医薬用途
FR2883876B1 (fr) *	2005-03-30	2007-05-04	Servier Lab	Derives d'indanyl-piperazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US7797124B2 (en)	2006-12-28	2010-09-14	American Underwater Products, Inc.	Dive computer with free dive mode and wireless data transmission
US9821893B2 (en) *	2014-10-06	2017-11-21	Pelagic Pressure Systems Corp.	System and methods for configurable dive masks with multiple interfaces

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2661176B1 (fr) *	1990-04-20	1992-06-12	Adir	Nouveau procede de preparation de la 1-(2,3,4-trimethoxybenzyl) piperazine en amination reductive.
JPH04356473A (ja) *	1991-05-31	1992-12-10	Wako Pure Chem Ind Ltd	ベンジルピペラジン誘導体の新規製造法
FR2681324B1 (fr) *	1991-09-18	1993-10-29	Adir Cie	Nouveaux derives de la trimetazidine, leur procede de preparation et les compositions pharmaceutiques les contenant.
FR2703048B1 (fr) *	1993-03-24	1996-01-05	Adir	Nouveaux composes n-benzylpiperazine, leur procede de preparation et les compositions pharmaceutiques les renfermant.
FR2757164B1 (fr) *	1996-12-16	1999-01-22	Adir	Nouveaux derives de n-benzylpiperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6479495B1 (en) *	1997-09-29	2002-11-12	Aventis Pharmaceuticals Inc.	Aminoalkylphenol derivatives and related compounds

2001
- 2001-07-16 FR FR0109454A patent/FR2827284B1/fr not_active Expired - Fee Related
2002
- 2002-07-12 MX MXPA02006900A patent/MXPA02006900A/es active IP Right Grant
- 2002-07-12 BR BR0202686-4A patent/BR0202686A/pt not_active Application Discontinuation
- 2002-07-15 NZ NZ520173A patent/NZ520173A/en not_active IP Right Cessation
- 2002-07-15 EA EA200200682A patent/EA005165B1/ru not_active IP Right Cessation
- 2002-07-15 JP JP2002205661A patent/JP2003096057A/ja active Pending
- 2002-07-15 KR KR10-2002-0041113A patent/KR100498867B1/ko not_active IP Right Cessation
- 2002-07-15 NO NO20023409A patent/NO20023409L/no unknown
- 2002-07-15 HU HU0202293A patent/HUP0202293A3/hu unknown
- 2002-07-15 AR ARP020102635A patent/AR034779A1/es unknown
- 2002-07-16 ES ES02291784T patent/ES2241973T3/es not_active Expired - Lifetime
- 2002-07-16 US US10/195,948 patent/US6686360B2/en not_active Expired - Fee Related
- 2002-07-16 DK DK02291784T patent/DK1277746T3/da active
- 2002-07-16 ZA ZA200205666A patent/ZA200205666B/xx unknown
- 2002-07-16 CN CN02124182A patent/CN1397554A/zh active Pending
- 2002-07-16 SI SI200230129T patent/SI1277746T1/xx unknown
- 2002-07-16 PL PL02355066A patent/PL355066A1/xx not_active Application Discontinuation
- 2002-07-16 PT PT02291784T patent/PT1277746E/pt unknown
- 2002-07-16 AU AU2002300150A patent/AU2002300150B2/en not_active Ceased
- 2002-07-16 DE DE60204083T patent/DE60204083T2/de not_active Expired - Lifetime
- 2002-07-16 AT AT02291784T patent/ATE295358T1/de active
- 2002-07-16 EP EP02291784A patent/EP1277746B1/fr not_active Expired - Lifetime
- 2002-07-16 CA CA002394010A patent/CA2394010A1/fr not_active Abandoned

Also Published As

Publication number	Publication date
EA005165B1 (ru)	2004-12-30
EA200200682A1 (ru)	2003-02-27
FR2827284B1 (fr)	2003-10-31
US20030158207A1 (en)	2003-08-21
ES2241973T3 (es)	2005-11-01
ATE295358T1 (de)	2005-05-15
BR0202686A (pt)	2003-05-06
PL355066A1 (en)	2003-01-27
SI1277746T1 (pt)	2005-08-31
MXPA02006900A (es)	2010-11-17
EP1277746A3 (fr)	2003-08-13
HUP0202293A2 (hu)	2003-04-28
DE60204083T2 (de)	2006-03-16
FR2827284A1 (fr)	2003-01-17
NO20023409D0 (no)	2002-07-15
KR100498867B1 (ko)	2005-07-04
NO20023409L (no)	2003-01-17
AU2002300150B2 (en)	2007-10-11
NZ520173A (en)	2004-02-27
EP1277746A2 (fr)	2003-01-22
ZA200205666B (en)	2003-03-27
JP2003096057A (ja)	2003-04-03
CN1397554A (zh)	2003-02-19
AR034779A1 (es)	2004-03-17
KR20030007187A (ko)	2003-01-23
DE60204083D1 (de)	2005-06-16
HU0202293D0 (pt)	2002-09-28
DK1277746T3 (da)	2005-08-29
CA2394010A1 (fr)	2003-01-16
US6686360B2 (en)	2004-02-03
EP1277746B1 (fr)	2005-05-11
HUP0202293A3 (en)	2004-04-28

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