PT1183029E - Preparado farmaceutico contendo contendo o principio activo diamorfina e sua utilizacao num processo para o tratamento da dependencia de opiaceos - Google Patents
Preparado farmaceutico contendo contendo o principio activo diamorfina e sua utilizacao num processo para o tratamento da dependencia de opiaceosInfo
- Publication number
- PT1183029E PT1183029E PT00929536T PT00929536T PT1183029E PT 1183029 E PT1183029 E PT 1183029E PT 00929536 T PT00929536 T PT 00929536T PT 00929536 T PT00929536 T PT 00929536T PT 1183029 E PT1183029 E PT 1183029E
- Authority
- PT
- Portugal
- Prior art keywords
- opiaceal
- diamorphine
- dependence
- principle
- active
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Addiction (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19923551A DE19923551A1 (de) | 1999-05-21 | 1999-05-21 | Pharmazeutisches Präparat mit dem Wirkstoff Diamorphin und seine Verwendung in einem Verfahren zur Behandlung der Opiatsucht |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1183029E true PT1183029E (pt) | 2005-09-30 |
Family
ID=7908879
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT00929536T PT1183029E (pt) | 1999-05-21 | 2000-05-17 | Preparado farmaceutico contendo contendo o principio activo diamorfina e sua utilizacao num processo para o tratamento da dependencia de opiaceos |
Country Status (25)
Country | Link |
---|---|
US (1) | US20050053647A1 (pt) |
EP (1) | EP1183029B1 (pt) |
JP (1) | JP4892148B2 (pt) |
KR (1) | KR100742471B1 (pt) |
CN (1) | CN100457107C (pt) |
AR (1) | AR024013A1 (pt) |
AT (1) | ATE300301T1 (pt) |
AU (1) | AU772139B2 (pt) |
BR (1) | BR0011286A (pt) |
CA (1) | CA2372339C (pt) |
CZ (1) | CZ301230B6 (pt) |
DE (2) | DE19923551A1 (pt) |
DK (1) | DK1183029T3 (pt) |
ES (1) | ES2245311T3 (pt) |
HU (1) | HUP0201349A3 (pt) |
IL (2) | IL146277A0 (pt) |
MX (1) | MXPA01011921A (pt) |
NZ (1) | NZ515301A (pt) |
PL (1) | PL196741B1 (pt) |
PT (1) | PT1183029E (pt) |
RU (1) | RU2254130C2 (pt) |
TR (1) | TR200103302T2 (pt) |
TW (1) | TWI241910B (pt) |
WO (1) | WO2000071125A2 (pt) |
ZA (1) | ZA200109517B (pt) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19960154A1 (de) * | 1999-12-14 | 2001-07-12 | Lohmann Therapie Syst Lts | Flache Arzneizubereitung zur transmucosalen Verabreichung von Oxycodon oder einem vergleichbaren Wirkstoff in der Mundhöhle, für die Anwendung in der Schmerztherapie und Suchttherapie |
US6958389B2 (en) * | 2000-09-08 | 2005-10-25 | San-Ei Gen F.F.I. Inc. | Tetraphenylbacteriochlorin derivatives and compositions containing the same |
WO2003002071A2 (en) * | 2001-06-29 | 2003-01-09 | Lewandowski Leon J | Individualized addiction cessation therapy |
DE10159745A1 (de) | 2001-12-05 | 2003-07-03 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit verbessertem Langzeittragekomfort |
BR0215102A (pt) * | 2001-12-13 | 2004-11-03 | Vital Health Sciences Pty Ltd | Transporte transdermal de compostos, formulação tópica, método para melhorar a absorção da pele, método para a terapia de reposição hormonal, uso de um ou mais derivados de fosfato de um composto hidróxi farmacêutico em um sistema de aplicação transdermal, sistema de aplicação transdermal, método para aplicação de um composto hidróxi farmacêutico a um indivìduo e para melhorar a eficácia de uma formulação |
DE10237057A1 (de) * | 2002-08-09 | 2004-03-25 | Grünenthal GmbH | Opioid-Rezeptor-Antagonisten in Pflasterformulierungen |
AU2002950713A0 (en) | 2002-08-09 | 2002-09-12 | Vital Health Sciences Pty Ltd | Carrier |
EP1793803B1 (en) * | 2004-10-01 | 2012-11-07 | Ramscor, Inc. | Conveniently implantable sustained release drug compositions |
NZ565049A (en) | 2005-06-17 | 2012-02-24 | Vital Health Sciences Pty Ltd | A carrier comprising one or more DI and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof |
US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
US20070202185A1 (en) * | 2005-12-28 | 2007-08-30 | Kimberly-Clark Worldwide, Inc. | Microencapsulated Delivery Vehicles Having Fugitive Layers |
US20070145619A1 (en) * | 2005-12-28 | 2007-06-28 | Kimberly-Clark Worldwide, Inc. | Processes for producing microencapsulated delivery vehicles |
US20070148459A1 (en) * | 2005-12-28 | 2007-06-28 | Kimberly-Clark Worldwide, Inc. | Microencapsulated delivery vehicles |
US20070148448A1 (en) * | 2005-12-28 | 2007-06-28 | Kimberly-Clark Worldwide, Inc. | Microencapsulated delivery vehicles including cooling agents |
US7442439B2 (en) * | 2005-12-28 | 2008-10-28 | Kimberly-Clark Worldwide, Inc. | Microencapsulated heat delivery vehicles |
US7914891B2 (en) * | 2005-12-28 | 2011-03-29 | Kimberly-Clark Worldwide, Inc. | Wipes including microencapsulated delivery vehicles and phase change materials |
US20070145618A1 (en) * | 2005-12-28 | 2007-06-28 | Kimberly-Clark Worldwide, Inc. | Methods of making microencapsulated delivery vehicles |
US20070149435A1 (en) * | 2005-12-28 | 2007-06-28 | Kimberly-Clark Worldwide, Inc. | Cleansing composition including microencapsulated delivery vehicles |
US20070148446A1 (en) * | 2005-12-28 | 2007-06-28 | Kimberly-Clark Worldwide, Inc. | Wipes including microencapsulated delivery vehicles and processes of producing the same |
US7648046B2 (en) * | 2006-05-30 | 2010-01-19 | Kimberly-Clark Worldwide, Inc. | Dispensing system for dispensing warm wet wipes |
US7497351B2 (en) | 2006-05-30 | 2009-03-03 | Kimberly-Clark Worldwide, Inc. | Wet wipe dispensing system |
US7654412B2 (en) * | 2006-05-30 | 2010-02-02 | Kimberly-Clark Worldwide, Inc. | Wet wipe dispensing system for dispensing warm wet wipes |
US7799352B2 (en) * | 2006-08-09 | 2010-09-21 | Korea Atomic Energy Research Institute | Therapeutic hydrogel for atopic dermatitis and preparation method thereof |
US8192841B2 (en) * | 2006-12-14 | 2012-06-05 | Kimberly-Clark Worldwide, Inc. | Microencapsulated delivery vehicle having an aqueous core |
WO2008136699A1 (fr) * | 2007-05-04 | 2008-11-13 | Igor Alexandrovich Bazikov | Patch transdermique à microcapsules et procédé de fabrication correspondant |
NZ597621A (en) | 2007-05-25 | 2013-06-28 | Tolmar Therapeutics Inc | Sustained delivery formulations of risperidone compounds |
US7924142B2 (en) * | 2008-06-30 | 2011-04-12 | Kimberly-Clark Worldwide, Inc. | Patterned self-warming wipe substrates |
WO2011094814A1 (en) | 2010-02-05 | 2011-08-11 | Phosphagenics Limited | Carrier comprising non-neutralised tocopheryl phosphate |
WO2011120084A1 (en) | 2010-03-30 | 2011-10-06 | Phosphagenics Limited | Transdermal delivery patch |
US9272044B2 (en) | 2010-06-08 | 2016-03-01 | Indivior Uk Limited | Injectable flowable composition buprenorphine |
GB2481017B (en) | 2010-06-08 | 2015-01-07 | Rb Pharmaceuticals Ltd | Microparticle buprenorphine suspension |
WO2012122586A1 (en) | 2011-03-15 | 2012-09-20 | Phosphagenics Limited | New composition |
AU2012386221A1 (en) | 2012-07-26 | 2015-02-26 | Wockhardt Limited | Pharmaceutical composition comprising diamorphine for intranasal administration |
GB201404139D0 (en) | 2014-03-10 | 2014-04-23 | Rb Pharmaceuticals Ltd | Sustained release buprenorphine solution formulations |
WO2017096427A1 (en) | 2015-12-09 | 2017-06-15 | Phosphagenics Limited | Pharmaceutical formulation |
CA3045702A1 (en) | 2016-12-21 | 2018-06-28 | Phosphagenics Limited | Phosphorylation process of complex alcohols |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3797494A (en) * | 1969-04-01 | 1974-03-19 | Alza Corp | Bandage for the administration of drug by controlled metering through microporous materials |
US3760805A (en) * | 1971-01-13 | 1973-09-25 | Alza Corp | Osmotic dispenser with collapsible supply container |
US3996934A (en) * | 1971-08-09 | 1976-12-14 | Alza Corporation | Medical bandage |
US3742951A (en) * | 1971-08-09 | 1973-07-03 | Alza Corp | Bandage for controlled release of vasodilators |
US3987790A (en) * | 1975-10-01 | 1976-10-26 | Alza Corporation | Osmotically driven fluid dispenser |
US4031894A (en) * | 1975-12-08 | 1977-06-28 | Alza Corporation | Bandage for transdermally administering scopolamine to prevent nausea |
US4626539A (en) * | 1984-08-10 | 1986-12-02 | E. I. Dupont De Nemours And Company | Trandermal delivery of opioids |
DE3902013A1 (de) * | 1989-01-25 | 1990-09-20 | Knoll Ag | Pflaster zur transdermalen anwendung |
DE3939376C1 (pt) * | 1989-11-29 | 1991-05-08 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg, 5450 Neuwied, De | |
SE9003665D0 (sv) * | 1990-11-16 | 1990-11-16 | Kabivitrum Ab | Morphine prodrugs |
AU1183092A (en) * | 1991-02-06 | 1992-09-07 | Guy Parent | Antalgic ointment |
DE4238223C1 (de) * | 1992-11-12 | 1994-05-26 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System zur Verabreichung von Physostigmin an die Haut und Verfahren zu dessen Herstellung |
JPH0733681A (ja) * | 1993-05-18 | 1995-02-03 | Sekisui Chem Co Ltd | 経皮吸収貼付剤 |
PT654263E (pt) * | 1993-11-23 | 2002-06-28 | Euro Celtique Sa | Metodo para a preparacao de uma composicao de libertyacao prolongada |
US5843480A (en) * | 1994-03-14 | 1998-12-01 | Euro-Celtique, S.A. | Controlled release diamorphine formulation |
EP0672416A1 (en) * | 1994-03-14 | 1995-09-20 | Euro-Celtique S.A. | Pharmaceutical composition comprising diamorphine |
JPH08143458A (ja) * | 1994-11-17 | 1996-06-04 | Sekisui Chem Co Ltd | 経皮吸収貼付剤 |
DE19642043A1 (de) * | 1995-10-23 | 1997-04-24 | Hexal Ag | Transdermales therapeutisches System (TTS) für die Verabreichung von Wirkstoffen zur Behandlung von Drogenabhängigkeit oder Drogensucht |
GB9605867D0 (en) * | 1996-03-20 | 1996-05-22 | Svedman Paul | Transdermal device |
DE19654468C1 (de) * | 1996-12-27 | 1998-01-22 | Lohmann Therapie Syst Lts | Extrem flexibles, dermal oder transdermal wirkendes Pflaster und Verfahren zu seiner Herstellung |
US6143278A (en) * | 1998-02-23 | 2000-11-07 | Elkhoury; George F. | Topical application of opioid analgesic drugs such as morphine |
DE19901085C2 (de) * | 1999-01-14 | 2003-12-18 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit einer selbstklebenden Matrix, enthaltend organische Säure-Additionssalze von Alkaloiden des Morphin- bzw. Morphinantyps |
-
1999
- 1999-05-21 DE DE19923551A patent/DE19923551A1/de not_active Withdrawn
-
2000
- 2000-05-17 ES ES00929536T patent/ES2245311T3/es not_active Expired - Lifetime
- 2000-05-17 EP EP00929536A patent/EP1183029B1/de not_active Expired - Lifetime
- 2000-05-17 AU AU47577/00A patent/AU772139B2/en not_active Ceased
- 2000-05-17 BR BR0011286-0A patent/BR0011286A/pt not_active Application Discontinuation
- 2000-05-17 MX MXPA01011921A patent/MXPA01011921A/es active IP Right Grant
- 2000-05-17 PT PT00929536T patent/PT1183029E/pt unknown
- 2000-05-17 TR TR2001/03302T patent/TR200103302T2/xx unknown
- 2000-05-17 CA CA002372339A patent/CA2372339C/en not_active Expired - Fee Related
- 2000-05-17 RU RU2001134016/15A patent/RU2254130C2/ru not_active IP Right Cessation
- 2000-05-17 DE DE50010833T patent/DE50010833D1/de not_active Expired - Lifetime
- 2000-05-17 JP JP2001505144A patent/JP4892148B2/ja not_active Expired - Fee Related
- 2000-05-17 AT AT00929536T patent/ATE300301T1/de active
- 2000-05-17 KR KR1020017014818A patent/KR100742471B1/ko not_active IP Right Cessation
- 2000-05-17 HU HU0201349A patent/HUP0201349A3/hu unknown
- 2000-05-17 DK DK00929536T patent/DK1183029T3/da active
- 2000-05-17 CZ CZ20014187A patent/CZ301230B6/cs not_active IP Right Cessation
- 2000-05-17 WO PCT/EP2000/004458 patent/WO2000071125A2/de active IP Right Grant
- 2000-05-17 PL PL351681A patent/PL196741B1/pl not_active IP Right Cessation
- 2000-05-17 CN CNB008078823A patent/CN100457107C/zh not_active Expired - Fee Related
- 2000-05-17 IL IL14627700A patent/IL146277A0/xx active IP Right Grant
- 2000-05-17 NZ NZ515301A patent/NZ515301A/xx not_active IP Right Cessation
- 2000-05-18 TW TW089109605A patent/TWI241910B/zh not_active IP Right Cessation
- 2000-05-19 AR ARP000102385A patent/AR024013A1/es not_active Application Discontinuation
-
2001
- 2001-11-01 IL IL146277A patent/IL146277A/en not_active IP Right Cessation
- 2001-11-19 ZA ZA200109517A patent/ZA200109517B/en unknown
-
2004
- 2004-09-16 US US10/942,297 patent/US20050053647A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT1183029E (pt) | Preparado farmaceutico contendo contendo o principio activo diamorfina e sua utilizacao num processo para o tratamento da dependencia de opiaceos | |
ID22565A (id) | Penggunaan nanodispersi dalam formulasi akhir obat | |
EE9900075A (et) | 7a-( -aminoalküül)östratrieenid, nende valmistamise meetod, 7a-( -aminoalküül)östratrieene sisaldavad farmatseutilised preparaadid ja nende kasutamine ravimite valmistamiseks | |
EE05134B1 (et) | Adamantaani derivaadid, meetod nende valmistamiseks, neid sisaldavad ravimkoostised ja nende kasutamine ravis | |
ATE447947T1 (de) | Pharmazeutische zubereitungen zur behandlung von insulinresitenz | |
EE200300370A (et) | Atsüülitud 6,7,8,9-tetrahüdro-5H-bensotsükloheptenüülamiinid, nende valmistamismeetod, kasutamine ja farmatseutiline preparaat | |
EE200300369A (et) | Atsüülitud indanüülamiinid, nende valmistamismeetod, kasutamine ja farmatseutiline preparaat | |
CY2007001I2 (el) | Φαρμακευτικο σκευασμα για χρηση στη θεραπεια του διαβητη | |
BR9607476A (pt) | Formas de dosagem farmacêutica oral e em tablete processo para preparar a dosagem fixadx e para tratar efeitos colaterais gastrointestinais associados ao tratamento com nsaid em mamíferos e no homem e uso da forma de dosagem | |
EE200100431A (et) | 16-halogenoepotilooni derivaadid, nende valmistamismeetod ja farmatseutiline kasutamine | |
EE05109B1 (et) | Sulfoonamiidi derivaadid, nende kasutamine meditsiinis ning meetod nende valmistamiseks | |
IT1271462B (it) | Antagonisti delle tachichinine,procedimento per la loro preparazione e loro impiego in formulazioni farmaceutiche. | |
HUP0203028A3 (en) | Pharmaceutical formulation containing tolterodine and its use | |
EE200100568A (et) | 6-alkenüül-, 6-alkünüül- ja 6-epoksüepotilooni derivaadid, nende valmistamismeetod ja kasutamine farmatseutilistes preparaatides | |
BR0112962B1 (pt) | Composições farmacêuticas compreendendo ácido hialurônico, ácido glicirretínico e polivinilpirrolidona, e uso desses compostos na preparação de medicamentos | |
EE04273B1 (et) | Bensotsüklohepteenid, nende valmistamise meetod, neid sisaldavad farmatseutilised preparaadid ja nende kasutamine ravimite valmistamiseks | |
EE200400028A (et) | Ravimpreparaat, selle valmistamise meetod ja selle kasutamine meditsiinis | |
AU9018898A (en) | Phosphazole-containing nucleoside analogs, related compounds, pharmaceutical compositions thereof, and their use in in vitro medicinal treatments | |
DE60037816D1 (de) | Pharmazeutische formulierung enthaltend megalatran und dessen pro-pharmaka | |
PT1230230E (pt) | Derivados de indeno-di-hidrotiazole sua preparacao e sua utilizacao como medicamentos anorexigenico | |
AU2000255628A1 (en) | Formulation comprising thymol useful in the treatment of drug resistant bacterial infections | |
PT1228039E (pt) | N-guanidinoalquilamidas sua preparacao sua utilizacao e preparacoes farmaceuticas contendo as mesmas | |
NO323466B1 (no) | Nye kinolinyl-piperidin-4-yliden-metyl-benzamidderivater, fremgangsmate til fremstilling derav, anvendelse derav i medikamenter til behandling av smerte, samt farmasoytisk sammensetning som innbefatter slike derivater | |
BR0012184B1 (pt) | compostos derivados de indol, formulação farmacêutica, e, composição e uso dos compostos na fabricação de medicamentos | |
ITMI922779A1 (it) | Antagonisti delle tachichinine, procedimento per la loro preparazione e loro impiego in formulazioni farmaceutiche |