PT1135383E - Solvatos mistos de propan-2-ol de paroxetina - Google Patents
Solvatos mistos de propan-2-ol de paroxetinaInfo
- Publication number
- PT1135383E PT1135383E PT99973027T PT99973027T PT1135383E PT 1135383 E PT1135383 E PT 1135383E PT 99973027 T PT99973027 T PT 99973027T PT 99973027 T PT99973027 T PT 99973027T PT 1135383 E PT1135383 E PT 1135383E
- Authority
- PT
- Portugal
- Prior art keywords
- propan
- solvate
- paranxin
- mixed
- crystalline
- Prior art date
Links
- 239000012453 solvate Substances 0.000 title abstract 5
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 title abstract 3
- AHOUBRCZNHFOSL-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine Chemical compound C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 abstract 4
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 229960005183 paroxetine hydrochloride Drugs 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- 230000009466 transformation Effects 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 150000008280 chlorinated hydrocarbons Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9826182.9A GB9826182D0 (en) | 1998-11-30 | 1998-11-30 | Novel process |
GBGB9916257.0A GB9916257D0 (en) | 1999-07-12 | 1999-07-12 | Novel compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1135383E true PT1135383E (pt) | 2004-04-30 |
Family
ID=26314751
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT99973027T PT1135383E (pt) | 1998-11-30 | 1999-11-30 | Solvatos mistos de propan-2-ol de paroxetina |
Country Status (9)
Country | Link |
---|---|
EP (2) | EP1408039A3 (pt) |
JP (1) | JP2002531452A (pt) |
AT (1) | ATE255577T1 (pt) |
AU (1) | AU1397900A (pt) |
DE (1) | DE69913377T2 (pt) |
DK (1) | DK1135383T3 (pt) |
ES (1) | ES2211232T3 (pt) |
PT (1) | PT1135383E (pt) |
WO (1) | WO2000032594A1 (pt) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL1017421C2 (nl) | 2001-02-21 | 2002-01-15 | Synthon Bv | Werkwijze voor het vervaardigen van paroxetine. |
WO2007054978A2 (en) * | 2005-11-10 | 2007-05-18 | Jubilant Organosys Limited | Process for preparing paroxetine hydrochloride hemihydrate |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
GB8430581D0 (en) * | 1984-12-04 | 1985-01-09 | Ferrosan As | Treatment |
ES2058061T3 (es) * | 1985-10-25 | 1994-11-01 | Beecham Group Plc | Derivado de piperidina, su preparacion y su uso como medicamento. |
AR001982A1 (es) * | 1995-02-06 | 1998-01-07 | Smithkline Beecham Plc | Clorhidrato de paroxetina anhidratado, y procedimiento para su preparacion |
EP1384720A1 (en) * | 1996-06-13 | 2004-01-28 | SUMIKA FINE CHEMICALS Co., Ltd. | Process for drying paroxetine hydrochloride |
HU221921B1 (hu) * | 1996-07-08 | 2003-02-28 | Richter Gedeon Vegyészeti Gyár Rt. | N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására |
-
1999
- 1999-11-30 PT PT99973027T patent/PT1135383E/pt unknown
- 1999-11-30 DE DE69913377T patent/DE69913377T2/de not_active Expired - Lifetime
- 1999-11-30 AU AU13979/00A patent/AU1397900A/en not_active Abandoned
- 1999-11-30 AT AT99973027T patent/ATE255577T1/de active
- 1999-11-30 DK DK99973027T patent/DK1135383T3/da active
- 1999-11-30 EP EP03078795A patent/EP1408039A3/en not_active Withdrawn
- 1999-11-30 EP EP99973027A patent/EP1135383B1/en not_active Expired - Lifetime
- 1999-11-30 ES ES99973027T patent/ES2211232T3/es not_active Expired - Lifetime
- 1999-11-30 JP JP2000585236A patent/JP2002531452A/ja not_active Withdrawn
- 1999-11-30 WO PCT/GB1999/003993 patent/WO2000032594A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1135383A1 (en) | 2001-09-26 |
EP1408039A3 (en) | 2004-05-12 |
JP2002531452A (ja) | 2002-09-24 |
EP1408039A2 (en) | 2004-04-14 |
AU1397900A (en) | 2000-06-19 |
DE69913377D1 (de) | 2004-01-15 |
ES2211232T3 (es) | 2004-07-01 |
WO2000032594A1 (en) | 2000-06-08 |
DE69913377T2 (de) | 2004-12-30 |
DK1135383T3 (da) | 2004-04-05 |
ATE255577T1 (de) | 2003-12-15 |
EP1135383B1 (en) | 2003-12-03 |
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