PT1133283E - Um metodo de producao de particulas de farmaco - Google Patents
Um metodo de producao de particulas de farmacoInfo
- Publication number
- PT1133283E PT1133283E PT99963729T PT99963729T PT1133283E PT 1133283 E PT1133283 E PT 1133283E PT 99963729 T PT99963729 T PT 99963729T PT 99963729 T PT99963729 T PT 99963729T PT 1133283 E PT1133283 E PT 1133283E
- Authority
- PT
- Portugal
- Prior art keywords
- particles
- pharmaco
- production
- susceptible
- degradation
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000002245 particle Substances 0.000 title abstract 2
- 230000015556 catabolic process Effects 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/04—Solvent extraction of solutions which are liquid
- B01D11/0403—Solvent extraction of solutions which are liquid with a supercritical fluid
- B01D11/0411—Solvent extraction of solutions which are liquid with a supercritical fluid the supercritical fluid acting as solvent for the solvent and as anti-solvent for the solute, e.g. formation of particles from solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9804003A SE9804003D0 (sv) | 1998-11-23 | 1998-11-23 | A method of producing drug particles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1133283E true PT1133283E (pt) | 2005-01-31 |
Family
ID=20413380
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99963729T PT1133283E (pt) | 1998-11-23 | 1999-11-22 | Um metodo de producao de particulas de farmaco |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6596315B1 (pt) |
| EP (1) | EP1133283B1 (pt) |
| JP (1) | JP4612191B2 (pt) |
| AT (1) | ATE278390T1 (pt) |
| AU (1) | AU754385B2 (pt) |
| CA (1) | CA2349711C (pt) |
| DE (1) | DE69920945T2 (pt) |
| DK (1) | DK1133283T3 (pt) |
| ES (1) | ES2228148T3 (pt) |
| PT (1) | PT1133283E (pt) |
| SE (1) | SE9804003D0 (pt) |
| WO (1) | WO2000030612A1 (pt) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
| CA2290893C (en) * | 1999-11-16 | 2007-05-01 | Bernard Charles Sherman | Magnesium omeprazole |
| GB0016040D0 (en) * | 2000-06-29 | 2000-08-23 | Glaxo Group Ltd | Novel process for preparing crystalline particles |
| GB0027357D0 (en) | 2000-11-09 | 2000-12-27 | Bradford Particle Design Plc | Particle formation methods and their products |
| AU2002221320B2 (en) * | 2000-12-08 | 2006-06-15 | The University Of Sydney | Synthesis of small particles |
| AUPR197000A0 (en) * | 2000-12-08 | 2001-01-11 | Unisearch Limited | Synthesis of small particles |
| US6667344B2 (en) | 2001-04-17 | 2003-12-23 | Dey, L.P. | Bronchodilating compositions and methods |
| US20030055026A1 (en) | 2001-04-17 | 2003-03-20 | Dey L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
| GB0208742D0 (en) | 2002-04-17 | 2002-05-29 | Bradford Particle Design Ltd | Particulate materials |
| US7186796B2 (en) | 2002-02-25 | 2007-03-06 | Phasex Corporation | Method for drying water-borne materials |
| ATE551991T1 (de) * | 2002-04-15 | 2012-04-15 | Map Pharmaceuticals Inc | Formulierung aus feinen teilchen mit verflüssigten oder dichten gasen |
| US7582284B2 (en) | 2002-04-17 | 2009-09-01 | Nektar Therapeutics | Particulate materials |
| WO2004020436A1 (en) * | 2002-08-30 | 2004-03-11 | Reddy's Laboratories Limited | Amorphous hydrates of esomeprazole magnesium and process for the preparation thereof |
| US20040242642A1 (en) * | 2002-11-18 | 2004-12-02 | Dr. Reddy's Laboratories Limited | Crystalline esomeprazole compounds and process for the preparation thereof |
| GB2401547B (en) | 2003-05-08 | 2005-07-20 | Nektar Therapeutics Uk Ltd | Particulate materials |
| TWI359675B (en) | 2003-07-10 | 2012-03-11 | Dey L P | Bronchodilating β-agonist compositions |
| US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| EP1904219A4 (en) | 2005-07-15 | 2011-07-27 | Map Pharmaceuticals Inc | METHOD FOR FORMING PARTICLES |
| WO2007138606A2 (en) * | 2006-06-01 | 2007-12-06 | Dexcel Pharma Technologies Ltd. | Multiple unit pharmaceutical formulation |
| MX2009008582A (es) | 2007-02-11 | 2009-10-30 | Map Pharmaceuticals Inc | Metodo para la administracion terapeutica de dihidroergotamina para permitir un rapido alivio de la migraña mientras se minimiza el perfil de efectos secundarios. |
| US9808030B2 (en) | 2011-02-11 | 2017-11-07 | Grain Processing Corporation | Salt composition |
| WO2016174664A1 (en) | 2015-04-29 | 2016-11-03 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
| WO2017145146A1 (en) | 2016-02-25 | 2017-08-31 | Dexcel Pharma Technologies Ltd. | Compositions comprising proton pump inhibitors |
| US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3744329A1 (de) | 1987-12-28 | 1989-07-06 | Schwarz Pharma Gmbh | Verfahren zur herstellung einer mindestens einen wirkstoff und einen traeger umfassenden zubereitung |
| WO1990003782A2 (en) * | 1988-10-05 | 1990-04-19 | The Upjohn Company | Finely divided solid crystalline powders via precipitation into an anti-solvent |
| AU5171293A (en) * | 1992-10-14 | 1994-05-09 | Regents Of The University Of Colorado, The | Ion-pairing of drugs for improved efficacy and delivery |
| GB9413202D0 (en) | 1994-06-30 | 1994-08-24 | Univ Bradford | Method and apparatus for the formation of particles |
| CA2206782C (en) | 1994-12-22 | 2007-04-03 | Astra Aktiebolag | Aerosol drug formulations |
| DE69637441T2 (de) * | 1995-10-17 | 2009-03-05 | Jagotec Ag | Verabreichung unlöslicher arzneistoffe |
| SE510666C2 (sv) | 1996-12-20 | 1999-06-14 | Astra Ab | Nya Kristallmodifikationer |
-
1998
- 1998-11-23 SE SE9804003A patent/SE9804003D0/xx unknown
-
1999
- 1999-11-22 US US09/486,688 patent/US6596315B1/en not_active Expired - Fee Related
- 1999-11-22 JP JP2000583496A patent/JP4612191B2/ja not_active Expired - Fee Related
- 1999-11-22 AT AT99963729T patent/ATE278390T1/de active
- 1999-11-22 WO PCT/SE1999/002152 patent/WO2000030612A1/en active IP Right Grant
- 1999-11-22 EP EP99963729A patent/EP1133283B1/en not_active Expired - Lifetime
- 1999-11-22 PT PT99963729T patent/PT1133283E/pt unknown
- 1999-11-22 ES ES99963729T patent/ES2228148T3/es not_active Expired - Lifetime
- 1999-11-22 DK DK99963729T patent/DK1133283T3/da active
- 1999-11-22 AU AU20102/00A patent/AU754385B2/en not_active Ceased
- 1999-11-22 CA CA002349711A patent/CA2349711C/en not_active Expired - Fee Related
- 1999-11-22 DE DE69920945T patent/DE69920945T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2349711C (en) | 2008-07-15 |
| DE69920945T2 (de) | 2005-08-25 |
| SE9804003D0 (sv) | 1998-11-23 |
| AU754385B2 (en) | 2002-11-14 |
| ATE278390T1 (de) | 2004-10-15 |
| CA2349711A1 (en) | 2000-06-02 |
| JP2002530317A (ja) | 2002-09-17 |
| WO2000030612A1 (en) | 2000-06-02 |
| EP1133283A1 (en) | 2001-09-19 |
| JP4612191B2 (ja) | 2011-01-12 |
| DE69920945D1 (de) | 2004-11-11 |
| US6596315B1 (en) | 2003-07-22 |
| EP1133283B1 (en) | 2004-10-06 |
| ES2228148T3 (es) | 2005-04-01 |
| DK1133283T3 (da) | 2005-01-24 |
| AU2010200A (en) | 2000-06-13 |
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