PT1117642E - Derivados de 1,3-diaril-2-piridin-2-il-3(piridin-2-ilamino) -propanol substituidos, procedimentos para a sua preparacao, farmacos contendo estes compostos e a sua aplicacao - Google Patents
Derivados de 1,3-diaril-2-piridin-2-il-3(piridin-2-ilamino) -propanol substituidos, procedimentos para a sua preparacao, farmacos contendo estes compostos e a sua aplicacaoInfo
- Publication number
- PT1117642E PT1117642E PT99948791T PT99948791T PT1117642E PT 1117642 E PT1117642 E PT 1117642E PT 99948791 T PT99948791 T PT 99948791T PT 99948791 T PT99948791 T PT 99948791T PT 1117642 E PT1117642 E PT 1117642E
- Authority
- PT
- Portugal
- Prior art keywords
- pyridin
- ilamino
- diary
- substituted
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19845406A DE19845406C2 (de) | 1998-10-02 | 1998-10-02 | Substituierte 1,3-Diaryl-2-pyridin-2-yl-3-(pyridin-2-ylamino)- propanolderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1117642E true PT1117642E (pt) | 2004-09-30 |
Family
ID=7883187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99948791T PT1117642E (pt) | 1998-10-02 | 1999-09-18 | Derivados de 1,3-diaril-2-piridin-2-il-3(piridin-2-ilamino) -propanol substituidos, procedimentos para a sua preparacao, farmacos contendo estes compostos e a sua aplicacao |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6596728B1 (pt) |
| EP (1) | EP1117642B1 (pt) |
| JP (1) | JP4544746B2 (pt) |
| KR (1) | KR100609255B1 (pt) |
| CN (1) | CN1173951C (pt) |
| AR (1) | AR021845A1 (pt) |
| AT (1) | ATE267809T1 (pt) |
| AU (1) | AU757689B2 (pt) |
| BR (1) | BR9915027B1 (pt) |
| CA (1) | CA2345985C (pt) |
| CZ (1) | CZ299569B6 (pt) |
| DE (2) | DE19845406C2 (pt) |
| DK (1) | DK1117642T3 (pt) |
| ES (1) | ES2219066T3 (pt) |
| HK (1) | HK1051533A1 (pt) |
| HU (1) | HU226688B1 (pt) |
| ID (1) | ID29249A (pt) |
| PL (1) | PL205034B1 (pt) |
| PT (1) | PT1117642E (pt) |
| RU (1) | RU2224748C2 (pt) |
| TR (1) | TR200100896T2 (pt) |
| WO (1) | WO2000020393A1 (pt) |
| ZA (1) | ZA200102587B (pt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE338039T1 (de) * | 2000-12-21 | 2006-09-15 | Sanofi Aventis Deutschland | Diphenylazetidinonderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| JP2005505538A (ja) * | 2001-08-22 | 2005-02-24 | アベンティス・ファーマ・ドイチユラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | アリール置換プロパノールアミン誘導体と他の活性成分との組み合わせ物およびその使用 |
| DE10219987A1 (de) * | 2002-05-03 | 2004-04-08 | Aventis Pharma Deutschland Gmbh | Optisch aktive β-Aminoketone, optisch aktive 1,3-Aminoalkohole und Verfahren zu deren Herstellung |
| US7161008B2 (en) * | 2002-05-03 | 2007-01-09 | Sanofi - Aventis Deutschland GmbH | Optically active β-aminoketones, optically active 1,3-amino alcohols and processes for preparing them |
| GB0307918D0 (en) | 2003-04-05 | 2003-05-14 | Astrazeneca Ab | Therapeutic use |
| US7816353B2 (en) * | 2003-10-24 | 2010-10-19 | Exelixis, Inc. | P70S6 kinase modulators and method of use |
| US20110294767A1 (en) | 2010-05-26 | 2011-12-01 | Satiogen Pharmaceuticals, Inc. | Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions |
| EP2770990A4 (en) | 2011-10-28 | 2015-03-11 | Lumena Pharmaceuticals Inc | Gallic acid refluxing agent for the treatment of hypertension and chronic liver disease |
| US20140243281A1 (en) | 2011-10-28 | 2014-08-28 | Lumena Pharmaceuticals, Inc. | Bile acid recycling inhibitors for treatment of pediatric cholestatic liver diseases |
| CN105228607A (zh) | 2013-03-15 | 2016-01-06 | 鲁美纳医药公司 | 用于治疗原发性硬化性胆管炎和炎性肠病的胆汁酸再循环抑制剂 |
| MX2015013196A (es) | 2013-03-15 | 2016-04-15 | Lumena Pharmaceuticals Inc | Inhibidores de reciclaje de acidos biliares para el tratamiento de la enfermedad de reflujo gastroesofagico y esofago de barrett. |
| JP6361168B2 (ja) * | 2013-06-17 | 2018-07-25 | Jsr株式会社 | 液晶配向剤、液晶配向膜、液晶表示素子、液晶表示素子の製造方法、重合体及び化合物 |
| ES2982943T3 (es) | 2019-02-12 | 2024-10-21 | Mirum Pharmaceuticals Inc | Métodos para aumentar el crecimiento en sujetos pediátricos con hepatopatía colestásica |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0000816A1 (en) * | 1977-08-06 | 1979-02-21 | Beecham Group Plc | Substituted amino-pyridine derivatives, processes for their preparation and pharmaceutical compositions containing them |
| DE19845402B4 (de) * | 1998-10-02 | 2005-04-07 | Aventis Pharma Deutschland Gmbh | Mit Heterocyclen substituierte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
| EP0869121B1 (de) * | 1997-04-04 | 2004-06-09 | Aventis Pharma Deutschland GmbH | Hypolipidämische Propanolaminderivate |
| DE19845405C2 (de) * | 1998-10-02 | 2000-07-13 | Aventis Pharma Gmbh | Arylsubstituierte Propanolaminderivate und deren Verwendung |
-
1998
- 1998-10-02 DE DE19845406A patent/DE19845406C2/de not_active Expired - Fee Related
-
1999
- 1999-09-18 BR BRPI9915027-1A patent/BR9915027B1/pt not_active IP Right Cessation
- 1999-09-18 CA CA2345985A patent/CA2345985C/en not_active Expired - Fee Related
- 1999-09-18 JP JP2000574510A patent/JP4544746B2/ja not_active Expired - Fee Related
- 1999-09-18 WO PCT/EP1999/006933 patent/WO2000020393A1/de active IP Right Grant
- 1999-09-18 KR KR1020017004096A patent/KR100609255B1/ko not_active IP Right Cessation
- 1999-09-18 HU HU0103533A patent/HU226688B1/hu not_active IP Right Cessation
- 1999-09-18 CZ CZ20011152A patent/CZ299569B6/cs not_active IP Right Cessation
- 1999-09-18 TR TR2001/00896T patent/TR200100896T2/xx unknown
- 1999-09-18 ES ES99948791T patent/ES2219066T3/es not_active Expired - Lifetime
- 1999-09-18 AU AU61926/99A patent/AU757689B2/en not_active Ceased
- 1999-09-18 CN CNB99811636XA patent/CN1173951C/zh not_active Expired - Fee Related
- 1999-09-18 PL PL347096A patent/PL205034B1/pl unknown
- 1999-09-18 ID IDW20010736A patent/ID29249A/id unknown
- 1999-09-18 RU RU2001111841/04A patent/RU2224748C2/ru not_active IP Right Cessation
- 1999-09-18 AT AT99948791T patent/ATE267809T1/de active
- 1999-09-18 PT PT99948791T patent/PT1117642E/pt unknown
- 1999-09-18 DE DE59909606T patent/DE59909606D1/de not_active Expired - Lifetime
- 1999-09-18 EP EP99948791A patent/EP1117642B1/de not_active Expired - Lifetime
- 1999-09-18 DK DK99948791T patent/DK1117642T3/da active
- 1999-09-30 AR ARP990104960A patent/AR021845A1/es active IP Right Grant
- 1999-10-01 US US09/410,083 patent/US6596728B1/en not_active Expired - Lifetime
-
2001
- 2001-03-29 ZA ZA200102587A patent/ZA200102587B/en unknown
-
2003
- 2003-05-27 HK HK03103726A patent/HK1051533A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT1086113E (pt) | Derivados de benzotiepina-1,1-dioxido processos para a sua preparacao medicamentos contendo estes compostos e sua utilizacao | |
| EE9800277A (et) | 4-aminopürimidiinderivaadid, neid ühendeid sisaldavad ravimid, nende kasutamine ja meetod nende valmistamiseks | |
| BR9708004A (pt) | PirimidoÚ5,4¾pirimidinas medicamentos contendo estes compostos seu emprego e processos para sua preparação | |
| DE69833464D1 (de) | Pharmazeutische Zusammensetzung, enthaltend 2,3-Diaryl-PyrazoloÄ1,5-bÜPyridazin Derivate | |
| PT1169313E (pt) | Derivados 1,4-benzotiazepina-1,1-dioxido substituidos com grupos acucar processo para a sua preparacao medicamento contendo estes compostos e sua utilizacao | |
| PT102291A (pt) | Metanossulfonato de paroxetina processos para a sua preparacao composicao farmaceutica contendo o mesmo e sua utilizacao | |
| BR9810802B1 (pt) | composto, composição farmacêutica, e, processo para a preparação de um composto. | |
| BR9910900B1 (pt) | compostos derivados de isotiazol, processo para sua preparação e composição farmacêutica dos mesmos | |
| PT812195E (pt) | Composicao farmaceutica para compostos de piperidinoalcanol | |
| BR9801606B1 (pt) | composto, processo para sua preparação, substáncia farmacêutica, uso do composto e processo para a produção de uma substáncia farmacêutica. | |
| EE9900115A (et) | Modifitseeritud aminohapped, neid ühendeid sisaldavad ravimid ja nende valmistamise meetod | |
| BRPI9810519B1 (pt) | derivados de 4''-substituìdo-9-desoxo-9a-aza-9a-homoeritromicina a e composição farmacêutica compreendendo os mesmos. | |
| NO953874D0 (no) | Farmasöytisk preparat inneholdende lipofile legemidler | |
| BR9912980B1 (pt) | Composição farmacêutica administrável oralmente, tablete de mascar contendo a mesma e utilização da mesma | |
| PT885204E (pt) | Novos derivados de arilglicinamida, processo para a sua preparacao e composicoes farmaceuticas que contem estes compostos | |
| EE04904B1 (et) | Tiobensimidasooli derivaadid ja farmatseutiline kompositsioon | |
| ATE264677T1 (de) | Feste arzneizubereitung enthaltend benzofuranderivate | |
| CY2013003I2 (el) | Φωσφονοκεφεμικα παραγωγα, διαδικασια για την παρασκευη τους, και χρηση αυτων | |
| EE9700333A (et) | Substitueeritud 4-fenüülaminotiasoolid, nende valmistamise meetod ja neid sisaldavad farmakoloogilised kompositsioonid | |
| PT1117661E (pt) | Derivados de propanolaminas substituidos com heterociclos, procedimento para a sua preparacao, farmacos contendo estes compostos e a sua aplicacao | |
| BR9609327A (pt) | Novos derivados de oxazolidinona processos para sua preparação e agentes farmacêuticos que contêm estes compostos | |
| HUP0102292A3 (en) | Substituted thiazolidinedione derivative, process for its preparation and its pharmaceutical use | |
| PT1117642E (pt) | Derivados de 1,3-diaril-2-piridin-2-il-3(piridin-2-ilamino) -propanol substituidos, procedimentos para a sua preparacao, farmacos contendo estes compostos e a sua aplicacao | |
| FI970058A0 (fi) | Uusi suun kautta annettava farmaseuttinen valmiste, joka sisältää omepratsolin magnesiumsuolaa | |
| EE200100027A (et) | Fosfororgaanilised ühendid, neid sisaldav farmatseutiline preparaat ja nende kasutamine |