PT1060161E - Inibidores de metaloproteinas de matriz - Google Patents
Inibidores de metaloproteinas de matrizInfo
- Publication number
- PT1060161E PT1060161E PT99904732T PT99904732T PT1060161E PT 1060161 E PT1060161 E PT 1060161E PT 99904732 T PT99904732 T PT 99904732T PT 99904732 T PT99904732 T PT 99904732T PT 1060161 E PT1060161 E PT 1060161E
- Authority
- PT
- Portugal
- Prior art keywords
- alkyl
- phenyl
- optionally substituted
- group
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- C07D249/18—Benzotriazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/38—Amides of thiocarboxylic acids
- C07C327/40—Amides of thiocarboxylic acids having carbon atoms of thiocarboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C327/42—Amides of thiocarboxylic acids having carbon atoms of thiocarboxamide groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of a saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/38—Amides of thiocarboxylic acids
- C07C327/40—Amides of thiocarboxylic acids having carbon atoms of thiocarboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C327/44—Amides of thiocarboxylic acids having carbon atoms of thiocarboxamide groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D317/34—Oxygen atoms
- C07D317/36—Alkylene carbonates; Substituted alkylene carbonates
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9804504.0A GB9804504D0 (en) | 1998-03-03 | 1998-03-03 | Matrix metalloproteinase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1060161E true PT1060161E (pt) | 2003-10-31 |
Family
ID=10827909
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT99904732T PT1060161E (pt) | 1998-03-03 | 1999-02-23 | Inibidores de metaloproteinas de matriz |
Country Status (19)
Country | Link |
---|---|
US (1) | US6277876B1 (pt) |
EP (1) | EP1060161B1 (pt) |
JP (1) | JP2002505320A (pt) |
KR (1) | KR20010034168A (pt) |
CN (1) | CN1205181C (pt) |
AT (1) | ATE242764T1 (pt) |
AU (1) | AU741867B2 (pt) |
CA (1) | CA2317502A1 (pt) |
DE (1) | DE69908756T2 (pt) |
DK (1) | DK1060161T3 (pt) |
ES (1) | ES2201668T3 (pt) |
GB (1) | GB9804504D0 (pt) |
HK (1) | HK1033666A1 (pt) |
HU (1) | HUP0100564A3 (pt) |
NZ (1) | NZ505458A (pt) |
PL (1) | PL342667A1 (pt) |
PT (1) | PT1060161E (pt) |
RU (1) | RU2205825C2 (pt) |
WO (1) | WO1999044989A1 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2352337C2 (ru) * | 2002-11-12 | 2009-04-20 | Алькон, Инк. | Ингибиторы гистондеацетилазы для лечения офтальмологических неоваскулярных нарушений и заболеваний |
EP1594459B1 (en) | 2002-12-30 | 2010-02-17 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
AU2004263900A1 (en) | 2003-08-08 | 2005-02-17 | Arriva Pharmaceuticals, Inc. | Methods of protein production in yeast |
GB0319917D0 (en) * | 2003-08-23 | 2003-09-24 | British Biotech Pharm | Metalloproteinase inhibitors |
PT1660471E (pt) | 2003-08-23 | 2011-08-03 | Merck Serono Sa | Derivados de ácido hidroxâmico como inibidores de metaloproteinase |
US7914771B2 (en) | 2004-03-09 | 2011-03-29 | Arriva Pharmaceuticals, Inc. | Treatment of chronic obstructive pulmonary disease by low dose inhalation of protease inhibitor |
GB0818907D0 (en) * | 2008-10-15 | 2008-11-19 | Isis Innovation | Histone lysine demethylase inhibitors |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4743587A (en) * | 1985-09-10 | 1988-05-10 | G. D. Searle & Co. | Hydroxamic acid based collagenase inhibitors |
EP0489579B1 (en) * | 1990-12-03 | 1995-03-29 | Celltech Therapeutics Limited | Peptidyl derivatives |
GB9423914D0 (en) | 1994-11-26 | 1995-01-11 | British Biotech Pharm | Polyether derivatives as metalloproteinase inhibitors |
-
1998
- 1998-03-03 GB GBGB9804504.0A patent/GB9804504D0/en not_active Ceased
-
1999
- 1999-02-23 AT AT99904732T patent/ATE242764T1/de not_active IP Right Cessation
- 1999-02-23 CN CNB998025933A patent/CN1205181C/zh not_active Expired - Fee Related
- 1999-02-23 PT PT99904732T patent/PT1060161E/pt unknown
- 1999-02-23 HU HU0100564A patent/HUP0100564A3/hu unknown
- 1999-02-23 DE DE69908756T patent/DE69908756T2/de not_active Expired - Fee Related
- 1999-02-23 NZ NZ505458A patent/NZ505458A/xx unknown
- 1999-02-23 CA CA002317502A patent/CA2317502A1/en not_active Abandoned
- 1999-02-23 EP EP99904732A patent/EP1060161B1/en not_active Expired - Lifetime
- 1999-02-23 ES ES99904732T patent/ES2201668T3/es not_active Expired - Lifetime
- 1999-02-23 DK DK99904732T patent/DK1060161T3/da active
- 1999-02-23 JP JP2000534533A patent/JP2002505320A/ja active Pending
- 1999-02-23 KR KR1020007007791A patent/KR20010034168A/ko not_active Application Discontinuation
- 1999-02-23 WO PCT/DK1999/000072 patent/WO1999044989A1/en not_active Application Discontinuation
- 1999-02-23 AU AU25125/99A patent/AU741867B2/en not_active Ceased
- 1999-02-23 PL PL99342667A patent/PL342667A1/xx not_active Application Discontinuation
- 1999-02-23 RU RU2000124933/04A patent/RU2205825C2/ru not_active IP Right Cessation
- 1999-02-23 US US09/623,428 patent/US6277876B1/en not_active Expired - Fee Related
-
2001
- 2001-06-19 HK HK01104217A patent/HK1033666A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NZ505458A (en) | 2002-10-25 |
AU2512599A (en) | 1999-09-20 |
HUP0100564A2 (hu) | 2001-07-30 |
ATE242764T1 (de) | 2003-06-15 |
JP2002505320A (ja) | 2002-02-19 |
CN1289323A (zh) | 2001-03-28 |
CN1205181C (zh) | 2005-06-08 |
EP1060161A1 (en) | 2000-12-20 |
KR20010034168A (ko) | 2001-04-25 |
RU2205825C2 (ru) | 2003-06-10 |
PL342667A1 (en) | 2001-07-02 |
CA2317502A1 (en) | 1999-09-10 |
AU741867B2 (en) | 2001-12-13 |
HK1033666A1 (en) | 2001-09-14 |
DK1060161T3 (da) | 2003-10-06 |
EP1060161B1 (en) | 2003-06-11 |
HUP0100564A3 (en) | 2003-07-28 |
DE69908756T2 (de) | 2004-04-29 |
US6277876B1 (en) | 2001-08-21 |
GB9804504D0 (en) | 1998-04-29 |
DE69908756D1 (de) | 2003-07-17 |
WO1999044989A1 (en) | 1999-09-10 |
ES2201668T3 (es) | 2004-03-16 |
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