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PT1012293E - Compostos para a imunoterapia e diagnóstico da tuberculose e métodos da sua utilização - Google Patents

Compostos para a imunoterapia e diagnóstico da tuberculose e métodos da sua utilização Download PDF

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Publication number
PT1012293E
PT1012293E PT98924827T PT98924827T PT1012293E PT 1012293 E PT1012293 E PT 1012293E PT 98924827 T PT98924827 T PT 98924827T PT 98924827 T PT98924827 T PT 98924827T PT 1012293 E PT1012293 E PT 1012293E
Authority
PT
Portugal
Prior art keywords
sequences
polypeptide
antigen
dna
given
Prior art date
Application number
PT98924827T
Other languages
English (en)
Inventor
Yasir A W Skeiky
Davin C Dillon
Antonio Campos-Neto
Mark R Alderson
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corixa Corp filed Critical Corixa Corp
Publication of PT1012293E publication Critical patent/PT1012293E/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PT98924827T 1997-05-20 1998-05-20 Compostos para a imunoterapia e diagnóstico da tuberculose e métodos da sua utilização PT1012293E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85938197A 1997-05-20 1997-05-20
US09/073,010 US6613881B1 (en) 1997-05-20 1998-05-05 Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use

Publications (1)

Publication Number Publication Date
PT1012293E true PT1012293E (pt) 2009-04-08

Family

ID=26754016

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98924827T PT1012293E (pt) 1997-05-20 1998-05-20 Compostos para a imunoterapia e diagnóstico da tuberculose e métodos da sua utilização

Country Status (20)

Country Link
US (1) US6613881B1 (pt)
EP (4) EP2172551A3 (pt)
JP (4) JP4162155B2 (pt)
KR (4) KR100924475B1 (pt)
AT (1) ATE420180T1 (pt)
AU (1) AU742751B2 (pt)
BR (1) BR9809445A (pt)
CA (2) CA2783134A1 (pt)
CZ (2) CZ300866B6 (pt)
DE (1) DE69840449D1 (pt)
DK (1) DK1012293T3 (pt)
ES (1) ES2321039T3 (pt)
HU (1) HU226520B1 (pt)
IL (2) IL133056A0 (pt)
NO (4) NO324880B1 (pt)
NZ (1) NZ501310A (pt)
PL (1) PL191121B1 (pt)
PT (1) PT1012293E (pt)
TR (1) TR200000115T2 (pt)
WO (1) WO1998053075A2 (pt)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6991797B2 (en) 1993-07-02 2006-01-31 Statens Serum Institut M. tuberculosis antigens
US6458366B1 (en) 1995-09-01 2002-10-01 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6592877B1 (en) 1995-09-01 2003-07-15 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6290969B1 (en) * 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6982085B2 (en) 1997-04-02 2006-01-03 Statens Serum Institut TB diagnostic based on antigens from M. tuberculosis
US7037510B2 (en) 1997-04-18 2006-05-02 Statens Serum Institut Hybrids of M. tuberculosis antigens
US7087713B2 (en) 2000-02-25 2006-08-08 Corixa Corporation Compounds and methods for diagnosis and immunotherapy of tuberculosis
JP4280309B2 (ja) * 1997-06-06 2009-06-17 ザ リージェンツ オブ ザ ユニバーシティー オブ カリフォルニア Ｄｎａ免疫刺激配列活性の阻害剤
EP1029053A1 (en) * 1997-11-10 2000-08-23 Statens Seruminstitut Nucleic acid fragments and polypeptide fragments derived from mycobacterium tuberculosis
CA2348475A1 (en) 1998-11-04 2000-05-11 Isis Innovation Limited Tuberculosis diagnostic test
US20030027774A1 (en) * 1999-03-18 2003-02-06 Ronald C. Hendrickson Tuberculosis antigens and methods of use therefor
US8143386B2 (en) * 1999-04-07 2012-03-27 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
JP5010079B2 (ja) * 1999-07-13 2012-08-29 スタテンズ セーラム インスティテュート マイコバクテリウム・ツベルクローシスｅｓａｔ−６遺伝子ファミリーベースの結核ワクチン及び診断法
CA2386841A1 (en) * 1999-10-07 2001-04-12 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
US6316205B1 (en) 2000-01-28 2001-11-13 Genelabs Diagnostics Pte Ltd. Assay devices and methods of analyte detection
AU2001250294A1 (en) * 2000-04-19 2001-10-30 Statens Serum Institut Tuberculosis antigens and methods of use thereof
EP1542732B1 (en) * 2000-06-20 2009-09-16 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
AU2003213118A1 (en) * 2002-02-15 2003-09-09 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
US20050164168A1 (en) * 2003-03-28 2005-07-28 Cullum Malford E. Method for the rapid diagnosis of infectious disease by detection and quantitation of microorganism induced cytokines
US8475735B2 (en) * 2004-11-01 2013-07-02 Uma Mahesh Babu Disposable immunodiagnostic test system
EA012037B1 (ru) * 2004-11-16 2009-06-30 Круселл Холланд Б.В. Поливалентные вакцины, содержащие рекомбинантные вирусные векторы
WO2006117538A2 (en) * 2005-04-29 2006-11-09 Fusion Antibodies Limited Assays for diagnosis of tuberculosis and uses thereof
CN101365714A (zh) 2005-07-01 2009-02-11 福赛特儿童口腔医院 结核抗原的检测分析及疫苗
WO2007041539A1 (en) * 2005-09-30 2007-04-12 Transcutaneous Technologies, Inc. Iontophoresis apparatus and method for the diagnosis of tuberculosis
US7842299B2 (en) 2006-03-14 2010-11-30 Oregon Health & Science University Methods for producing an immune response to tuberculosis
EA201100070A1 (ru) 2008-07-25 2011-10-31 Глаксо Груп Лимитед Туберкулезный белок rv2386c, композиции и их применения
EA022203B1 (ru) 2008-07-25 2015-11-30 Глаксосмитклайн Байолоджикалс С.А. Способы и композиции для лечения или предупреждения туберкулёза
CN102164952B (zh) 2008-07-25 2016-05-25 葛兰素史密丝克莱恩生物有限公司 新型组合物和方法
UA110103C2 (uk) 2010-01-27 2015-11-25 Ґлаксосмітклайн Байолоджікалз С.А. Модифікований туберкульозний антиген
GB201012072D0 (en) 2010-07-19 2010-09-01 Sec Dep For Environment Food A Diagnostic reagents
WO2012177656A2 (en) 2011-06-19 2012-12-27 Abogen, Inc. Devices, solutions and methods for sample collection
EP3256849A4 (en) 2015-02-09 2018-12-05 Abogen, Inc. Devices, solutions and methods for sample collection related applications, analysis and diagnosis

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
US4689397A (en) 1985-08-12 1987-08-25 Scripps Clinic And Research Foundation Synthetic polypeptides for detecting mycobacterial infections
US4935233A (en) 1985-12-02 1990-06-19 G. D. Searle And Company Covalently linked polypeptide cell modulators
US4879213A (en) 1986-12-05 1989-11-07 Scripps Clinic And Research Foundation Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse
US4976958A (en) * 1987-02-26 1990-12-11 Scripps Clinic And Research Foundation Mycobacterial recombinants and peptides
US4952395A (en) 1987-02-26 1990-08-28 Scripps Clinic And Research Foundation Mycobacterial recombinants and peptides
US6037135A (en) * 1992-08-07 2000-03-14 Epimmune Inc. Methods for making HLA binding peptides and their uses
US5330754A (en) 1992-06-29 1994-07-19 Archana Kapoor Membrane-associated immunogens of mycobacteria
CA2179772A1 (en) * 1993-12-23 1995-06-29 William R. Jacobs Mycobacteria virulence factors and a method for their identification
AU706367B2 (en) * 1995-03-13 1999-06-17 Astra Aktiebolag New DNA molecules
US6290969B1 (en) * 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
NZ319377A (en) 1995-09-01 2000-01-28 Corixa Corp polypeptides comprising a portion of a soluble M tuberculosis antigen
DK2154248T3 (da) 1995-09-01 2012-01-30 Corixa Corp Forbindelser og fremgangsmåder til diagnose af tuberkulose
TR199901569T2 (xx) * 1996-10-11 2000-12-21 Corixa Corporation T�berk�lozun te�hisi i�in bile�ikler ve y�ntemler.

Also Published As

Publication number Publication date
EP2270170A1 (en) 2011-01-05
HUP0003402A3 (en) 2001-03-28
JP2008245644A (ja) 2008-10-16
KR20010012812A (ko) 2001-02-26
BR9809445A (pt) 2000-06-13
CA2783134A1 (en) 1998-11-26
NO20075900L (no) 2000-01-18
HU226520B1 (en) 2009-03-30
DE69840449D1 (de) 2009-02-26
NO20075902L (no) 2000-01-18
DK1012293T3 (da) 2009-05-04
EP2248900A1 (en) 2010-11-10
JP2002514084A (ja) 2002-05-14
TR200000115T2 (tr) 2000-11-21
KR100924475B1 (ko) 2009-11-03
NZ501310A (en) 2001-09-28
KR20080036663A (ko) 2008-04-28
IL133056A0 (en) 2001-03-19
EP1012293A2 (en) 2000-06-28
IL133056A (en) 2010-11-30
AU742751B2 (en) 2002-01-10
JP4759010B2 (ja) 2011-08-31
HUP0003402A2 (hu) 2000-12-28
WO1998053075A2 (en) 1998-11-26
PL337330A1 (en) 2000-08-14
EP2270170B1 (en) 2013-11-06
EP2172551A2 (en) 2010-04-07
JP2008253260A (ja) 2008-10-23
NO995689D0 (no) 1999-11-19
JP4162155B2 (ja) 2008-10-08
CZ300866B6 (cs) 2009-08-26
EP1012293B1 (en) 2009-01-07
CA2290774A1 (en) 1998-11-26
EP2172551A3 (en) 2010-11-10
KR100909640B1 (ko) 2009-07-27
KR20070026886A (ko) 2007-03-08
PL191121B1 (pl) 2006-03-31
JP2008283961A (ja) 2008-11-27
WO1998053075A3 (en) 1999-04-01
NO20075901L (no) 2000-01-18
KR20060066139A (ko) 2006-06-15
KR100893118B1 (ko) 2009-04-14
ATE420180T1 (de) 2009-01-15
CZ410099A3 (cs) 2000-05-17
CZ303194B6 (cs) 2012-05-23
KR100652513B1 (ko) 2006-12-01
AU7690798A (en) 1998-12-11
EP2248900B1 (en) 2012-07-18
ES2321039T3 (es) 2009-06-01
US6613881B1 (en) 2003-09-02
NO995689L (no) 2000-01-18
JP4759011B2 (ja) 2011-08-31
NO324880B1 (no) 2007-12-27
JP4764445B2 (ja) 2011-09-07

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