PT100216A - N- 4,5-di-hidroxi- e 4,5,8-tri-hidroxi-9,10-di-hidro-9,10-dioxo-2-antracentil carbonil -aminoacidos uteis na terapia de afeccoes osteoarticulares, processo para a sua preparacao e composicoes farmaceuticas que os contem - Google Patents

N- 4,5-di-hidroxi- e 4,5,8-tri-hidroxi-9,10-di-hidro-9,10-dioxo-2-antracentil carbonil -aminoacidos uteis na terapia de afeccoes osteoarticulares, processo para a sua preparacao e composicoes farmaceuticas que os contem

Info

Publication number: PT100216A
Authority: PT; Portugal
Prior art keywords: hydroxy; anthracentyl; osteoarticular; affections; dioxo
Prior art date: 1991-03-12

Application number

PT100216A

Other languages

English (en)

Other versions

PT100216B (pt

Inventor

Sergio Rosini

Maurizio Mian

Original Assignee

Gentili Ist Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-03-12

Filing date

1992-03-09

Publication date

1993-05-31

1992-03-09 Application filed by Gentili Ist Spa filed Critical Gentili Ist Spa

1993-05-31 Publication of PT100216A publication Critical patent/PT100216A/pt

1999-06-30 Publication of PT100216B publication Critical patent/PT100216B/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/84—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
- C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
- C07C323/59—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton with acylated amino groups bound to the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
- C07C2603/24—Anthracenes; Hydrogenated anthracenes

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

PT100216A 1991-03-12 1992-03-09 N-{{4,5-di-hidroxi- e 4,5,8-tri-hidroxi-9,10-di-hidro-9,10-dioxo-2-antracentil} carbonil}-aminoacidos uteis na terapia de afeccoes osteoarticulares, processo para a sua preparacao e composicoes farmaceuticas que os contem PT100216B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ITMI910658A IT1244773B (it)	1991-03-12	1991-03-12	N-(4,5-diidrossi-e 4,5,8-triidrossi-9,10-diidro-9,10-diosso-2- antracen-il)carbonil) amminoacidi utilizzabili nella terapia delle affezioni osteoarticolari

Publications (2)

Publication Number	Publication Date
PT100216A true PT100216A (pt)	1993-05-31
PT100216B PT100216B (pt)	1999-06-30

Family

ID=11359001

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT100216A PT100216B (pt)	1991-03-12	1992-03-09	N-{{4,5-di-hidroxi- e 4,5,8-tri-hidroxi-9,10-di-hidro-9,10-dioxo-2-antracentil} carbonil}-aminoacidos uteis na terapia de afeccoes osteoarticulares, processo para a sua preparacao e composicoes farmaceuticas que os contem

Country Status (21)

Country	Link
US (1)	US5451606A (pt)
EP (1)	EP0588797B1 (pt)
JP (1)	JP2979054B2 (pt)
KR (1)	KR100224330B1 (pt)
AT (1)	ATE134363T1 (pt)
AU (1)	AU661475B2 (pt)
CA (1)	CA2105683C (pt)
CZ (1)	CZ282997B6 (pt)
DE (1)	DE69208464T2 (pt)
DK (1)	DK0588797T3 (pt)
ES (1)	ES2084348T3 (pt)
FI (1)	FI113167B (pt)
GR (1)	GR3019069T3 (pt)
HU (1)	HU215436B (pt)
IT (1)	IT1244773B (pt)
MX (1)	MX9201055A (pt)
NO (1)	NO304592B1 (pt)
PT (1)	PT100216B (pt)
RU (1)	RU2111959C1 (pt)
SK (1)	SK280134B6 (pt)
WO (1)	WO1992016496A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0570091A1 (en) *	1992-02-28	1993-11-18	Lilly Industries Limited	Anthraquinone derivatives, process for their preparation and their use as medicaments
GB9417102D0 (en) *	1994-08-24	1994-10-12	Lilly Industries Ltd	Pharmaceutical compounds
IT1276781B1 (it) *	1995-06-23	1997-11-03	Gentili Ist Spa	Derivati antrachinonmono- e disolfon- sostituiti e composizioni farmaceutiche che li contengono per il trattamento delle patologie
GB2398780A (en) *	2003-02-26	2004-09-01	Arakis Ltd	1,8-dihydroxyanthraquinone-6-carboxamide derivatives as inhibitors of T-cell proliferation for treatment of autoimmune or inflammatory conditions
CN102060809B (zh) *	2009-05-01	2015-05-20	常州高新技术产业开发区三维工业技术研究所有限公司	一种大黄酸衍生物及其制备和用途
CN102225913B (zh) *	2011-04-07	2013-09-04	栗进才	大黄酸衍生物以及它们的治疗用途
RU2466134C1 (ru) *	2011-06-24	2012-11-10	Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Иркутский государственный университет"	Способ получения катионных комплексов палладия
CN104557603A (zh) *	2014-12-08	2015-04-29	石河子大学	一种大黄酸类化合物及制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA761627B (en) *	1976-03-16	1978-01-25	C Friedmann	Improvements in or relating to the treatment of arthritis
US4966918A (en) *	1989-01-27	1990-10-30	Sloan-Kettering Institute For Cancer Research	Derivatives of chryosphanol

1991
- 1991-03-12 IT ITMI910658A patent/IT1244773B/it active IP Right Grant
1992
- 1992-03-04 AU AU13596/92A patent/AU661475B2/en not_active Ceased
- 1992-03-04 SK SK947-93A patent/SK280134B6/sk unknown
- 1992-03-04 ES ES92905647T patent/ES2084348T3/es not_active Expired - Lifetime
- 1992-03-04 EP EP92905647A patent/EP0588797B1/en not_active Expired - Lifetime
- 1992-03-04 DK DK92905647.1T patent/DK0588797T3/da active
- 1992-03-04 DE DE69208464T patent/DE69208464T2/de not_active Expired - Fee Related
- 1992-03-04 HU HU9302510A patent/HU215436B/hu not_active IP Right Cessation
- 1992-03-04 CA CA002105683A patent/CA2105683C/en not_active Expired - Fee Related
- 1992-03-04 CZ CS931829A patent/CZ282997B6/cs not_active IP Right Cessation
- 1992-03-04 US US08/117,065 patent/US5451606A/en not_active Expired - Fee Related
- 1992-03-04 WO PCT/EP1992/000479 patent/WO1992016496A1/en active IP Right Grant
- 1992-03-04 KR KR1019930702709A patent/KR100224330B1/ko not_active IP Right Cessation
- 1992-03-04 RU RU93057732A patent/RU2111959C1/ru not_active IP Right Cessation
- 1992-03-04 AT AT92905647T patent/ATE134363T1/de not_active IP Right Cessation
- 1992-03-04 JP JP4505494A patent/JP2979054B2/ja not_active Expired - Fee Related
- 1992-03-09 PT PT100216A patent/PT100216B/pt active IP Right Grant
- 1992-03-11 MX MX9201055A patent/MX9201055A/es not_active IP Right Cessation
1993
- 1993-09-08 FI FI933925A patent/FI113167B/fi not_active IP Right Cessation
- 1993-09-10 NO NO933241A patent/NO304592B1/no not_active IP Right Cessation
1996
- 1996-02-22 GR GR960400457T patent/GR3019069T3/el unknown

Also Published As

Publication number	Publication date
HU9302510D0 (en)	1993-12-28
DE69208464T2 (de)	1996-07-11
DK0588797T3 (da)	1996-06-17
HUT65218A (en)	1994-05-02
PT100216B (pt)	1999-06-30
EP0588797B1 (en)	1996-02-21
NO933241L (no)	1993-09-10
CZ182993A3 (en)	1994-07-13
ITMI910658A1 (it)	1992-09-12
WO1992016496A1 (en)	1992-10-01
ES2084348T3 (es)	1996-05-01
CA2105683C (en)	2003-09-16
ATE134363T1 (de)	1996-03-15
CZ282997B6 (cs)	1997-12-17
SK280134B6 (sk)	1999-08-06
AU1359692A (en)	1992-10-21
JPH10502050A (ja)	1998-02-24
RU2111959C1 (ru)	1998-05-27
DE69208464D1 (en)	1996-03-28
MX9201055A (es)	1992-09-01
NO304592B1 (no)	1999-01-18
JP2979054B2 (ja)	1999-11-15
NO933241D0 (no)	1993-09-10
EP0588797A1 (en)	1994-03-30
GR3019069T3 (en)	1996-05-31
ITMI910658A0 (it)	1991-03-12
FI933925A0 (fi)	1993-09-08
US5451606A (en)	1995-09-19
FI933925A (fi)	1993-09-08
IT1244773B (it)	1994-08-08
KR100224330B1 (ko)	1999-10-15
FI113167B (fi)	2004-03-15
AU661475B2 (en)	1995-07-27
SK94793A3 (en)	1994-03-09
HU215436B (hu)	1999-09-28
CA2105683A1 (en)	1992-09-13

Publication	Publication Date	Title
PT99445A (pt)	1992-09-30	Processo para preparacao de derivados do 1,4,7,10-tetraazaciclododecano mono-n--substituidos e de composicoes farmaceuticas que os contem
BR9611015A (pt)	1999-09-14	Composto, composição farmacêutica e processo para o tratamento de uma doença inflamatória suscetìvel ao tratamento com um agente não-tóxico anti-inflamatório não-esteróide, sal farmaceuticamente aceitável, utilização de um composto
BR9407239A (pt)	1996-09-24	Azadioxacicloalquenos substituídos
BRPI0111116B8 (pt)	2021-05-25	imitadores de trombopoietina
IL115920A (en)	2003-11-23	PHARMACEUTICAL COMPOSITIONS CONTAINING omega-SUBSTITUTED 2,2-DICHLOROALKANECARBOXYLIC ACIDS, SOME SUCH NEW COMPOUNDS AND PROCESS FOR THEIR PREPARATION
MX9207494A (es)	1993-07-01	4(5)-amino-1,8-naftiridinas substituidas, procedimiento para su preparacion y composiciones farmaceuticas que las contienen.
FI972434A0 (fi)	1997-06-06	Lamotrigiiniä sisältävä farmaseuttinen koostumus
PT100216A (pt)	1993-05-31	N- 4,5-di-hidroxi- e 4,5,8-tri-hidroxi-9,10-di-hidro-9,10-dioxo-2-antracentil carbonil -aminoacidos uteis na terapia de afeccoes osteoarticulares, processo para a sua preparacao e composicoes farmaceuticas que os contem
PT100415A (pt)	1993-06-30	Novas morfolinas de accao farmaceutica, e processo para a sua preparacao
PE45195A1 (es)	1996-01-17	Derivado de aminoacido, procedimiento para su preparacion y composicion farmaceutica que lo contiene
ES2182975T3 (es)	2003-03-16	Nueva quimica heterociclica.
ES2086528T3 (es)	1996-07-01	Nuevos compuestos biciclicos sustituidos con amino.
DK0424504T3 (da)	1994-05-16	Nye 9alfa-hydroxy-3-oxo-4,24(25)-stigmastadien-26-syrederivater, fremgangsmåde til fremstilling deraf samt farmaceutiske præparater med indhold deraf
GR3019970T3 (en)	1996-08-31	Pharmaceutical compositions for use in treating aids
MX9304403A (es)	1994-04-29	Derivados farmacologicamente activos de ó-(aminometilo terciario)-bencenmetanol
PT100075A (pt)	1993-03-31	Acidos aril- ou arilalquil-acil-amino-alquil-hidroxidifosfonicos, um processo para a sua preparacao e sua utilizacao na terapia de perturbacoes do tecido osteoarticular e conjuntivo
ES8307778A1 (es)	1983-08-16	Procedimiento para preparar difenilbutil-1-piperazinocarboxilatos.
ES2137665T3 (es)	1999-12-16	Nuevos derivados de piridina o piridazina, procedimientos para su preparacion, y medicamentos que contienen estos compuestos.
AR019664A1 (es)	2002-03-13	Composicion para el tratamiento de enfermedades del cartilago
ZA944317B (en)	1995-12-18	New phosphonosuccinic acid derivatives processes for the preparation thereof and pharmaceutical compositions containing them
BR1100550A (pt)	2000-03-14	Disacarìdeos de antraciclina, processo para sua preparação, e composições farmacêuticas contendo os mesmos
NO961657L (no)	1996-06-25	Dibenz[b,eÅoksepinderivater, fremgangsmåte for fremstilling samt legemiddel inneholdende slike

Legal Events

Date	Code	Title	Description
1993-05-31	BB1A	Laying open of patent application	Effective date: 19930122
1999-06-30	FG3A	Patent granted, date of granting	Effective date: 19990325
1999-09-30	PC3A	Transfer or assignment	Free format text: 19990628 ABIOGEN PHARMA S.R.L. IT