PL3833964T3 - Zastosowanie spektroskopii ramana do produkcji proszków do inhalacji - Google Patents
Zastosowanie spektroskopii ramana do produkcji proszków do inhalacjiInfo
- Publication number
- PL3833964T3 PL3833964T3 PL19779127.0T PL19779127T PL3833964T3 PL 3833964 T3 PL3833964 T3 PL 3833964T3 PL 19779127 T PL19779127 T PL 19779127T PL 3833964 T3 PL3833964 T3 PL 3833964T3
- Authority
- PL
- Poland
- Prior art keywords
- manufacture
- application
- raman spectroscopy
- inhalation powders
- inhalation
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/21—Measuring
- B01F35/213—Measuring of the properties of the mixtures, e.g. temperature, density or colour
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/85—Investigating moving fluids or granular solids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/85—Investigating moving fluids or granular solids
- G01N2021/8592—Grain or other flowing solid samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/88—Investigating the presence of flaws or contamination
- G01N21/95—Investigating the presence of flaws or contamination characterised by the material or shape of the object to be examined
- G01N21/9508—Capsules; Tablets
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862715463P | 2018-08-07 | 2018-08-07 | |
PCT/IB2019/056737 WO2020031119A1 (en) | 2018-08-07 | 2019-08-07 | Application of raman spectroscopy for the manufacture of inhalation powders |
Publications (1)
Publication Number | Publication Date |
---|---|
PL3833964T3 true PL3833964T3 (pl) | 2023-09-04 |
Family
ID=68072878
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL19779127.0T PL3833964T3 (pl) | 2018-08-07 | 2019-08-07 | Zastosowanie spektroskopii ramana do produkcji proszków do inhalacji |
Country Status (6)
Country | Link |
---|---|
US (3) | US11774363B2 (pl) |
EP (2) | EP3833964B1 (pl) |
ES (1) | ES2953293T3 (pl) |
PL (1) | PL3833964T3 (pl) |
PT (1) | PT3833964T (pl) |
WO (1) | WO2020031119A1 (pl) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11774363B2 (en) * | 2018-08-07 | 2023-10-03 | Norton (Waterford) Limited | Application of raman spectroscopy for the manufacture of inhalation powders |
US20240033222A1 (en) | 2020-08-14 | 2024-02-01 | Norton (Waterford) Limited | An inhalable formulation of fluticasone propionate and albuterol sulfate |
GB202012742D0 (en) * | 2020-08-14 | 2020-09-30 | Norton Waterford Ltd | An inhalable medicament |
WO2024010538A1 (en) * | 2022-07-07 | 2024-01-11 | Arven Ilac Sanayi Ve Ticaret Anonim Sirketi | A process for the preparation of dry powder compositions for inhalation using different mixers |
Family Cites Families (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1242211A (en) | 1967-08-08 | 1971-08-11 | Fisons Pharmaceuticals Ltd | Pharmaceutical composition |
GB1381872A (en) | 1971-06-22 | 1975-01-29 | Fisons Ltd | Pharmaceutical compositions for inhalation |
US7448375B2 (en) | 1993-01-29 | 2008-11-11 | Aradigm Corporation | Method of treating diabetes mellitus in a patient |
GB9322014D0 (en) | 1993-10-26 | 1993-12-15 | Co Ordinated Drug Dev | Improvements in and relating to carrier particles for use in dry powder inhalers |
US7871598B1 (en) * | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
JP4044330B2 (ja) | 2001-12-25 | 2008-02-06 | ミネベア株式会社 | Rbc又はcrbcの微粉末が分散した合成樹脂発泡成型体、その製造方法及びその用途 |
US20050032235A1 (en) | 2003-06-18 | 2005-02-10 | Srinivas Tummala | Method of monitoring the blending of a mixture |
JP4607112B2 (ja) * | 2003-08-11 | 2011-01-05 | グラクソ グループ リミテッド | 医薬定量噴霧式吸入器及び前記吸引器に関連する方法 |
WO2005044186A2 (en) * | 2003-10-28 | 2005-05-19 | Glaxo Group Limited | Inhalable pharmaceutical formulations employing desiccating agents and methods of administering the same |
SE0303570L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | Fukt-känslig medicinsk produkt |
WO2005074575A2 (en) * | 2004-01-30 | 2005-08-18 | Microbia, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
KR101149275B1 (ko) | 2004-02-24 | 2012-05-25 | 마이크로도스 테라퓨특스, 인코포레이티드 | 합성 제트 기반 약제 운반 방법 및 장치 |
EP1761265A2 (en) * | 2004-06-28 | 2007-03-14 | ALZA Corporation | A drug/polymer complex, preferably ciprofloxacin/hpmc, its method of manufacturing using lyophilization and its use in an osmotic device |
WO2008021142A2 (en) * | 2006-08-09 | 2008-02-21 | Glaxo Group Limited | Process for manufacturing lactose |
UY31235A1 (es) * | 2007-07-21 | 2009-03-02 | Nuevos medicamentos pulverulentos que contienen tiotropio y salmeterol, asi como lactosa como excipiente | |
CN103908712A (zh) | 2008-03-27 | 2014-07-09 | 曼金德公司 | 干燥粉末吸入系统 |
EP2296628B1 (en) * | 2008-05-22 | 2014-05-14 | 3M Innovative Properties Company | Process for manufacturing flowable powder drug compositions |
MX2011000405A (es) * | 2008-07-18 | 2011-03-04 | Prosonix Ltd | Proceso para mejorar la cristalinidad. |
EP2221048A1 (en) | 2009-02-18 | 2010-08-25 | Siegfried Generics International AG | Pharmaceutical composition for inhalation |
WO2010128359A1 (en) * | 2009-05-07 | 2010-11-11 | Gea Pharma Systems Limited | Tablet production module and method for continuous production of tablets |
US9782542B2 (en) * | 2009-10-01 | 2017-10-10 | Momentive Performance Materials Inc. | Self-lubricating pharmaceutical syringe stoppers |
GB0918431D0 (en) * | 2009-10-21 | 2009-12-09 | Prosonix Ltd | Process for improving crystallinity |
WO2011069197A1 (en) | 2009-12-08 | 2011-06-16 | The University Of Sydney | Inhalable formulations |
RU2555772C2 (ru) * | 2009-12-14 | 2015-07-10 | КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. | Микрочастицы с антибиотиком для ингаляции |
RU2585101C2 (ru) * | 2010-04-01 | 2016-05-27 | КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. | Способ приготовления частиц носителя для сухих порошков для ингаляции |
DK2560611T3 (en) * | 2010-04-21 | 2018-02-26 | Chiesi Farm Spa | Process for providing particles with reduced electrostatic charges |
CA2803418A1 (en) * | 2010-06-22 | 2011-12-29 | Chiesi Farmaceutici S.P.A. | Dry powder formulation comprising an antimuscarinic drug |
US9061352B2 (en) * | 2010-08-30 | 2015-06-23 | Pulmatrix, Inc. | Dry powder formulations and methods for treating pulmonary diseases |
WO2012028745A1 (en) | 2010-09-03 | 2012-03-08 | Pharmaterials Limited | Pharmaceutical composition suitable for use in a dry powder inhaler |
RU2640921C2 (ru) * | 2010-09-29 | 2018-01-12 | Пулмэтрикс, Инк. | Катионы одновалентных металлов сухих порошков для ингаляций |
CN103153377A (zh) | 2010-09-30 | 2013-06-12 | 诺华有限公司 | 吸入器 |
WO2013052844A1 (en) * | 2011-10-07 | 2013-04-11 | Pulmatrix, Inc. | Methods for treating and diagnosing respiratory tract infections |
EP2768480A1 (en) * | 2011-10-21 | 2014-08-27 | Rigel Pharmaceuticals, Inc. | Method and device for administering xinafoate salt of n4-(2,2-difluoro-4h-benzo [1,4]oxazin-3-one) -6-yl]-5-fluoro-n2- [3- (methylaminocarbonylmethyleneoxy) phenyl]2,4-pyrimidinediamine |
US20130125882A1 (en) | 2011-11-17 | 2013-05-23 | Jonathan Matz | Method and composition for treating asthma and copd |
ES2929807T3 (es) * | 2012-01-25 | 2022-12-01 | Chiesi Farm Spa | Formulación en polvo seco que comprende un corticoesteroide y un beta-adrenérgico para administración por inhalación |
KR20150041608A (ko) * | 2012-02-28 | 2015-04-16 | 아이슈티카 홀딩스 인코포레이티드. | 흡입용 약제학적 조성물 |
EP2819672A1 (en) * | 2012-02-29 | 2015-01-07 | Pulmatrix, Inc. | Inhalable dry powders |
KR20130140358A (ko) * | 2012-06-14 | 2013-12-24 | 한미약품 주식회사 | 살메테롤 지나포산염, 플루티카손 프로피오네이트 및 티오트로피움 브로마이드를 포함하는 흡입 제형용 건조 분말 및 이의 제조방법 |
WO2014074797A1 (en) | 2012-11-09 | 2014-05-15 | Civitas Therapeutics, Inc. | Ultra low density pulmonary powders |
EP2738172A1 (en) | 2012-11-28 | 2014-06-04 | Almirall, S.A. | New bicyclic compounds as crac channel modulators |
GB201319265D0 (en) * | 2013-10-31 | 2013-12-18 | Norton Waterford Ltd | Medicament inhaler |
AR102305A1 (es) * | 2014-10-16 | 2017-02-15 | Teva Branded Pharmaceutical Products R&D Inc | Procedimiento para preparar formulación farmacéutica inhalable de polvo seco |
GB201614939D0 (en) * | 2016-09-02 | 2016-10-19 | Glaxosmithkline Ip Dev Ltd | Crystalline hydrate |
US11774363B2 (en) * | 2018-08-07 | 2023-10-03 | Norton (Waterford) Limited | Application of raman spectroscopy for the manufacture of inhalation powders |
US20240033222A1 (en) | 2020-08-14 | 2024-02-01 | Norton (Waterford) Limited | An inhalable formulation of fluticasone propionate and albuterol sulfate |
-
2019
- 2019-08-07 US US17/266,884 patent/US11774363B2/en active Active
- 2019-08-07 PT PT197791270T patent/PT3833964T/pt unknown
- 2019-08-07 EP EP19779127.0A patent/EP3833964B1/en active Active
- 2019-08-07 PL PL19779127.0T patent/PL3833964T3/pl unknown
- 2019-08-07 EP EP21181874.5A patent/EP3910324A1/en active Pending
- 2019-08-07 WO PCT/IB2019/056737 patent/WO2020031119A1/en unknown
- 2019-08-07 ES ES19779127T patent/ES2953293T3/es active Active
-
2021
- 2021-07-20 US US17/380,535 patent/US11366064B2/en active Active
-
2022
- 2022-05-16 US US17/745,686 patent/US12174121B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
WO2020031119A1 (en) | 2020-02-13 |
US20210372931A1 (en) | 2021-12-02 |
US20220276173A1 (en) | 2022-09-01 |
US11366064B2 (en) | 2022-06-21 |
PT3833964T (pt) | 2023-08-17 |
US11774363B2 (en) | 2023-10-03 |
US20210293715A1 (en) | 2021-09-23 |
EP3833964A1 (en) | 2021-06-16 |
US12174121B2 (en) | 2024-12-24 |
EP3910324A1 (en) | 2021-11-17 |
ES2953293T3 (es) | 2023-11-10 |
EP3833964B1 (en) | 2023-07-26 |
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