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PL3790874T3 - Nowe pochodne chinoliny o działaniu przeciw robakom pasożytniczym - Google Patents

Nowe pochodne chinoliny o działaniu przeciw robakom pasożytniczym

Info

Publication number
PL3790874T3
PL3790874T3 PL19722129.4T PL19722129T PL3790874T3 PL 3790874 T3 PL3790874 T3 PL 3790874T3 PL 19722129 T PL19722129 T PL 19722129T PL 3790874 T3 PL3790874 T3 PL 3790874T3
Authority
PL
Poland
Prior art keywords
anthelmintic
quinoline derivatives
quinoline
derivatives
anthelmintic quinoline
Prior art date
Application number
PL19722129.4T
Other languages
English (en)
Inventor
Walter Hübsch
Nils Griebenow
Hans-Georg Schwarz
Daniel Kulke
Claudia BÖHM
Kirsten BÖRNGEN
Bernd Alig
Wei Zhuang
Iring Heisler
Thomas Ilg
Johannes KÖBBERLING
Adeline KÖHLER
Niels Lindner
Ulrich Görgens
Claudia WELZ
Maike HINK
Original Assignee
Bayer Animal Health Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Animal Health Gmbh filed Critical Bayer Animal Health Gmbh
Publication of PL3790874T3 publication Critical patent/PL3790874T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
PL19722129.4T 2018-05-09 2019-05-07 Nowe pochodne chinoliny o działaniu przeciw robakom pasożytniczym PL3790874T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18171490 2018-05-09
PCT/EP2019/061725 WO2019215182A1 (en) 2018-05-09 2019-05-07 New quinoline derivatives

Publications (1)

Publication Number Publication Date
PL3790874T3 true PL3790874T3 (pl) 2023-06-19

Family

ID=62148180

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19722129.4T PL3790874T3 (pl) 2018-05-09 2019-05-07 Nowe pochodne chinoliny o działaniu przeciw robakom pasożytniczym

Country Status (21)

Country Link
US (2) US11572357B2 (pl)
EP (1) EP3790874B1 (pl)
JP (1) JP7403472B2 (pl)
KR (1) KR20210006401A (pl)
CN (1) CN112074514B (pl)
AU (1) AU2019266511B2 (pl)
BR (1) BR112020022619A2 (pl)
CA (1) CA3099610A1 (pl)
CL (1) CL2020002891A1 (pl)
CO (1) CO2020013876A2 (pl)
DK (1) DK3790874T3 (pl)
ES (1) ES2945559T3 (pl)
IL (1) IL278472B2 (pl)
MX (1) MX2020011873A (pl)
PH (1) PH12020551891A1 (pl)
PL (1) PL3790874T3 (pl)
PT (1) PT3790874T (pl)
SG (1) SG11202010024UA (pl)
TW (1) TWI813680B (pl)
UY (1) UY38226A (pl)
WO (1) WO2019215182A1 (pl)

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WO2020014068A1 (en) 2018-07-09 2020-01-16 Boehringer Ingelheim Animal Health USA Inc. Anthelminthic heterocyclic compounds
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WO2020191091A1 (en) 2019-03-19 2020-09-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic aza-benzothiophene and aza-benzofuran compounds
CN114845994B (zh) * 2019-12-18 2025-07-18 英特维特国际股份有限公司 包含喹啉结构的驱虫化合物
BR112022020315A2 (pt) 2020-04-09 2022-12-13 Bayer Animal Health Gmbh Novos compostos anti-helmínticos
IL298596A (en) 2020-05-29 2023-01-01 Boehringer Ingelheim Animal Health Usa Inc Anthelmintic heterocyclic compounds
JP2023553428A (ja) 2020-12-11 2023-12-21 インターベット インターナショナル ベー. フェー. チエノピリジン構造を含む駆虫剤化合物
EP4148052A1 (en) 2021-09-09 2023-03-15 Bayer Animal Health GmbH New quinoline derivatives
US11999742B2 (en) 2021-11-01 2024-06-04 Boehringer Ingelheim Vetmedica Gmbh Substituted pyrrolo[1,2-b]pyridazines as anthelmintics
WO2024213752A1 (en) 2023-04-14 2024-10-17 Elanco Animal Health Gmbh Long-term prevention and/or treatment of a disease by slo-1 inhibitors
WO2025027117A1 (en) 2023-08-02 2025-02-06 Intervet International B.V. Carboxamide-4-quinoline compounds with anthelmintic activity

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Also Published As

Publication number Publication date
MX2020011873A (es) 2021-01-20
TW202016100A (zh) 2020-05-01
CN112074514A (zh) 2020-12-11
KR20210006401A (ko) 2021-01-18
CA3099610A1 (en) 2019-11-14
TWI813680B (zh) 2023-09-01
US20210139468A1 (en) 2021-05-13
BR112020022619A2 (pt) 2021-02-02
WO2019215182A1 (en) 2019-11-14
PT3790874T (pt) 2023-05-31
US11572357B2 (en) 2023-02-07
DK3790874T3 (da) 2023-05-15
AU2019266511A1 (en) 2020-10-22
PH12020551891A1 (en) 2021-05-31
AU2019266511B2 (en) 2022-12-08
JP7403472B2 (ja) 2023-12-22
CN112074514B (zh) 2024-10-29
CL2020002891A1 (es) 2021-05-14
CO2020013876A2 (es) 2020-11-20
EP3790874A1 (en) 2021-03-17
EP3790874B1 (en) 2023-03-15
IL278472B2 (en) 2023-08-01
JP2021523131A (ja) 2021-09-02
SG11202010024UA (en) 2020-11-27
ES2945559T3 (es) 2023-07-04
IL278472A (pl) 2020-12-31
UY38226A (es) 2019-12-31
US20230141809A1 (en) 2023-05-11
IL278472B1 (en) 2023-04-01

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