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PL368520A1 - Sposób wytwarzania 4-amino-2,5-bisheterocyklilochinazolin - Google Patents

Sposób wytwarzania 4-amino-2,5-bisheterocyklilochinazolin

Info

Publication number
PL368520A1
PL368520A1 PL02368520A PL36852002A PL368520A1 PL 368520 A1 PL368520 A1 PL 368520A1 PL 02368520 A PL02368520 A PL 02368520A PL 36852002 A PL36852002 A PL 36852002A PL 368520 A1 PL368520 A1 PL 368520A1
Authority
PL
Poland
Prior art keywords
bisheterocyclylquinazolines
amino
production
Prior art date
Application number
PL02368520A
Other languages
English (en)
Inventor
Lee Terence Boulton
Robert James Crook
Alan John Pettman
Robert Walton
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of PL368520A1 publication Critical patent/PL368520A1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57Nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PL02368520A 2001-08-01 2002-07-19 Sposób wytwarzania 4-amino-2,5-bisheterocyklilochinazolin PL368520A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0118752.5A GB0118752D0 (en) 2001-08-01 2001-08-01 Process for the production of quinazolines

Publications (1)

Publication Number Publication Date
PL368520A1 true PL368520A1 (pl) 2005-04-04

Family

ID=9919612

Family Applications (1)

Application Number Title Priority Date Filing Date
PL02368520A PL368520A1 (pl) 2001-08-01 2002-07-19 Sposób wytwarzania 4-amino-2,5-bisheterocyklilochinazolin

Country Status (27)

Country Link
US (1) US7026479B2 (pl)
EP (1) EP1412331B1 (pl)
JP (1) JP2005501054A (pl)
KR (1) KR20040019097A (pl)
CN (1) CN1533378A (pl)
AP (1) AP1299A (pl)
AR (1) AR036204A1 (pl)
AT (1) ATE323677T1 (pl)
BR (1) BR0211670A (pl)
CA (1) CA2451075A1 (pl)
CZ (1) CZ2004151A3 (pl)
DE (1) DE60210778T2 (pl)
DO (1) DOP2002000443A (pl)
EG (1) EG23204A (pl)
ES (1) ES2260457T3 (pl)
GB (1) GB0118752D0 (pl)
HN (1) HN2002000197A (pl)
HU (1) HUP0401573A3 (pl)
IL (1) IL158998A0 (pl)
MX (1) MXPA04000978A (pl)
PA (1) PA8550301A1 (pl)
PE (1) PE20030346A1 (pl)
PL (1) PL368520A1 (pl)
RU (1) RU2261861C1 (pl)
UY (1) UY27399A1 (pl)
WO (1) WO2003011829A1 (pl)
ZA (1) ZA200309043B (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004006846A2 (en) 2002-07-15 2004-01-22 Exelixis, Inc. Receptor-type kinase modulators and methods of use
ATE532782T1 (de) * 2003-09-26 2011-11-15 Exelixis Inc C-met-modulatoren und anwendungsverfahren
KR20080095915A (ko) * 2004-05-06 2008-10-29 워너-램버트 캄파니 엘엘씨 4-페닐아미노-퀴나졸린-6-일-아미드
US7985753B2 (en) * 2006-08-04 2011-07-26 Merz Pharma Gmbh & Co. Kgaa Substituted pyrazolo[1,5-A]pyrimidines as metabotropic glutamate receptor modulators
RS52754B2 (sr) 2009-01-16 2022-08-31 Exelixis Inc Malat so n-(4- {[6,7-bis(metiloksi)hinolin-4-il]oksi}fenil-n'- (4-fluorofenil) ciklopropan-1,1-dikarboksamid-a, i njeni kristalni oblici za lečenje karcinoma
CN102427813A (zh) 2009-03-18 2012-04-25 雷斯韦洛吉克斯公司 新的抗炎剂
IN2012DN00352A (pl) * 2009-06-16 2015-08-21 Bikam Pharmaceuticals Inc
UA108618C2 (uk) 2009-08-07 2015-05-25 Застосування c-met-модуляторів в комбінації з темозоломідом та/або променевою терапією для лікування раку
AU2012346214B2 (en) 2011-11-30 2017-09-14 Bikam Pharmaceuticals, Inc. Opsin-binding ligands, compositions and methods of use
DK2906531T3 (en) * 2012-10-15 2018-02-05 Resverlogix Corp APPLICABLE COMPOUNDS IN THE SYNTHESIS OF BENZAMIDE COMPOUNDS
KR102662814B1 (ko) 2015-03-13 2024-05-03 리스버로직스 코퍼레이션 보체 관련 질환을 치료하기 위한 조성물 및 치료 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8719378D0 (en) * 1987-08-15 1987-09-23 Pfizer Ltd Antiarrythmic agents
US6069149A (en) * 1997-01-09 2000-05-30 Terumo Kabushiki Kaisha Amide derivatives and intermediates for the synthesis thereof

Also Published As

Publication number Publication date
UY27399A1 (es) 2003-02-28
ZA200309043B (en) 2004-11-22
DE60210778D1 (de) 2006-05-24
US20030100753A1 (en) 2003-05-29
ATE323677T1 (de) 2006-05-15
HUP0401573A2 (hu) 2005-01-28
GB0118752D0 (en) 2001-09-26
AP1299A (en) 2004-09-06
IL158998A0 (en) 2004-05-12
KR20040019097A (ko) 2004-03-04
US7026479B2 (en) 2006-04-11
CZ2004151A3 (cs) 2005-01-12
RU2004102692A (ru) 2005-07-10
AR036204A1 (es) 2004-08-18
EP1412331A1 (en) 2004-04-28
JP2005501054A (ja) 2005-01-13
DE60210778T2 (de) 2007-01-04
PA8550301A1 (es) 2003-09-05
CA2451075A1 (en) 2003-02-13
PE20030346A1 (es) 2003-04-05
EP1412331B1 (en) 2006-04-19
BR0211670A (pt) 2004-07-13
ES2260457T3 (es) 2006-11-01
WO2003011829A1 (en) 2003-02-13
MXPA04000978A (es) 2004-04-20
HUP0401573A3 (en) 2005-06-28
CN1533378A (zh) 2004-09-29
HN2002000197A (es) 2003-02-27
EG23204A (en) 2004-07-31
AP2002002602A0 (en) 2002-09-30
DOP2002000443A (es) 2003-02-15
RU2261861C1 (ru) 2005-10-10

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Legal Events

Date Code Title Description
REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)