PL360297A1 - Kompozycje farmaceutyczne zawierające akryloilowepochodne dystamycyny i inhibitory topoizomerazy Ii II - Google Patents

Kompozycje farmaceutyczne zawierające akryloilowepochodne dystamycyny i inhibitory topoizomerazy Ii II

Info

Publication number: PL360297A1
Authority: PL; Poland
Prior art keywords: topoisomerase; inhibitors; distamycin derivatives; acryloyl distamycin; combined therapy
Prior art date: 2000-06-23

Application number

PL36029701A

Other languages

English (en)

Other versions

PL200503B1 (pl

Inventor

Maria Cristina Rosa Geroni

Paolo Cozzi

Italo Beria

Original Assignee

Pharmacia Italia S.P.A.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-23

Filing date

2001-06-20

Publication date

2004-09-06

2001-06-20 Application filed by Pharmacia Italia S.P.A. filed Critical Pharmacia Italia S.P.A.

2004-09-06 Publication of PL360297A1 publication Critical patent/PL360297A1/pl

2009-01-30 Publication of PL200503B1 publication Critical patent/PL200503B1/pl

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Hematology (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PL360297A 2000-06-23 2001-06-20 Kompozycja farmaceutyczna zawierająca pochodną dystamycyny, produkt zawierający pochodną dystamycyny oraz zastosowanie pochodnej dystamycyny PL200503B1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0015444.3A GB0015444D0 (en)	2000-06-23	2000-06-23	Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors
PCT/EP2001/007059 WO2001097789A2 (en)	2000-06-23	2001-06-20	Pharmaceutical compositions comprising acryloyl distamycin derivatives and topoisomerase i and ii inhibitors

Publications (2)

Publication Number	Publication Date
PL360297A1 true PL360297A1 (pl)	2004-09-06
PL200503B1 PL200503B1 (pl)	2009-01-30

Family

ID=9894285

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL360297A PL200503B1 (pl)	2000-06-23	2001-06-20	Kompozycja farmaceutyczna zawierająca pochodną dystamycyny, produkt zawierający pochodną dystamycyny oraz zastosowanie pochodnej dystamycyny

Country Status (27)

Country	Link
US (1)	US20030162722A1 (pl)
EP (1)	EP1292290B1 (pl)
JP (1)	JP2003535890A (pl)
KR (1)	KR100853955B1 (pl)
CN (1)	CN1241573C (pl)
AT (1)	ATE323483T1 (pl)
AU (2)	AU7846301A (pl)
BR (1)	BR0111813A (pl)
CA (1)	CA2411172C (pl)
CZ (1)	CZ20024155A3 (pl)
DE (1)	DE60118914T2 (pl)
DK (1)	DK1292290T3 (pl)
EA (1)	EA006684B1 (pl)
EE (1)	EE05319B1 (pl)
ES (1)	ES2261448T3 (pl)
GB (1)	GB0015444D0 (pl)
HK (1)	HK1054334B (pl)
HU (1)	HUP0301257A2 (pl)
IL (1)	IL153177A0 (pl)
MX (1)	MXPA02012163A (pl)
NO (1)	NO329783B1 (pl)
NZ (1)	NZ523000A (pl)
PL (1)	PL200503B1 (pl)
PT (1)	PT1292290E (pl)
SK (1)	SK287549B6 (pl)
WO (1)	WO2001097789A2 (pl)
ZA (1)	ZA200209834B (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0015447D0 (en) *	2000-06-23	2000-08-16	Pharmacia & Upjohn Spa	Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents
GB0015444D0 (en) *	2000-06-23	2000-08-16	Pharmacia & Upjohn Spa	Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors
EP1461083B1 (en) *	2002-01-02	2006-03-29	Pharmacia Italia S.p.A.	Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and protein kinase (serine/threonine kinase) inhibitors
CN100438913C (zh) *	2004-11-22	2008-12-03	山东蓝金生物工程有限公司	一种抗癌药物组合物
MD23Z (ro) *	2008-12-02	2010-01-31	Василе ЖОВМИР	Metodă de tratament diferenţiat al carcinomului lobular in situ neinvaziv al glandei mamare
MD35Z (ro) *	2008-12-02	2010-01-31	Василе ЖОВМИР	Metodă de apreciere a riscului dezvoltării carcinomului neinvaziv in situ al glandei mamare
MD24Z (ro) *	2008-12-02	2010-01-31	Василе ЖОВМИР	Metodă de tratament diferenţiat al carcinomului neinvaziv al glandei mamare
MD36Z (ro) *	2008-12-02	2010-01-31	Василе ЖОВМИР	Metodă de tratament diferenţiat al carcinomului ductal in situ neinvaziv al glandei mamare
AU2011274229A1 (en)	2010-07-02	2013-01-10	Angiochem Inc.	Short and D-amino acid-containing polypeptides for therapeutic conjugates and uses thereof
CN109718228A (zh) *	2017-10-30	2019-05-07	沈阳药科大学	米托蒽醌的抗肿瘤淋巴转移作用及其药物制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9615692D0 (en) *	1996-07-25	1996-09-04	Pharmacia Spa	Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
GB9623522D0 (en) *	1996-11-11	1997-01-08	Pharmacia & Upjohn Spa	Benzoheterocycle distamycin derivatives process for preparing them and their use as antitumour and antiviral agents
GB9727524D0 (en) *	1997-12-31	1998-02-25	Pharmacia & Upjohn Spa	Synergistic antitumor composition containing a biologically active ureido compound
GB9806692D0 (en) *	1998-03-27	1998-05-27	Pharmacia & Upjohn Spa	Benzoheterocyclic distamycin derivatives, process for preparing them and their use as antitumour agents
GB0015444D0 (en) *	2000-06-23	2000-08-16	Pharmacia & Upjohn Spa	Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors

2000
- 2000-06-23 GB GBGB0015444.3A patent/GB0015444D0/en not_active Ceased
2001
- 2001-06-20 CN CNB018116396A patent/CN1241573C/zh not_active Expired - Fee Related
- 2001-06-20 SK SK1833-2002A patent/SK287549B6/sk not_active IP Right Cessation
- 2001-06-20 BR BR0111813-7A patent/BR0111813A/pt not_active Application Discontinuation
- 2001-06-20 EA EA200300060A patent/EA006684B1/ru not_active IP Right Cessation
- 2001-06-20 AU AU7846301A patent/AU7846301A/xx active Pending
- 2001-06-20 US US10/297,915 patent/US20030162722A1/en not_active Abandoned
- 2001-06-20 HU HU0301257A patent/HUP0301257A2/hu unknown
- 2001-06-20 NZ NZ523000A patent/NZ523000A/en unknown
- 2001-06-20 DE DE60118914T patent/DE60118914T2/de not_active Expired - Lifetime
- 2001-06-20 EP EP01956495A patent/EP1292290B1/en not_active Expired - Lifetime
- 2001-06-20 AT AT01956495T patent/ATE323483T1/de not_active IP Right Cessation
- 2001-06-20 CZ CZ20024155A patent/CZ20024155A3/cs unknown
- 2001-06-20 PL PL360297A patent/PL200503B1/pl not_active IP Right Cessation
- 2001-06-20 IL IL15317701A patent/IL153177A0/xx not_active IP Right Cessation
- 2001-06-20 ES ES01956495T patent/ES2261448T3/es not_active Expired - Lifetime
- 2001-06-20 MX MXPA02012163A patent/MXPA02012163A/es active IP Right Grant
- 2001-06-20 CA CA002411172A patent/CA2411172C/en not_active Expired - Fee Related
- 2001-06-20 EE EEP200200681A patent/EE05319B1/xx not_active IP Right Cessation
- 2001-06-20 KR KR1020027017440A patent/KR100853955B1/ko not_active IP Right Cessation
- 2001-06-20 WO PCT/EP2001/007059 patent/WO2001097789A2/en active IP Right Grant
- 2001-06-20 AU AU2001278463A patent/AU2001278463B2/en not_active Ceased
- 2001-06-20 JP JP2002503266A patent/JP2003535890A/ja not_active Abandoned
- 2001-06-20 DK DK01956495T patent/DK1292290T3/da active
- 2001-06-20 PT PT01956495T patent/PT1292290E/pt unknown
2002
- 2002-12-04 ZA ZA200209834A patent/ZA200209834B/en unknown
- 2002-12-18 NO NO20026078A patent/NO329783B1/no not_active IP Right Cessation
2003
- 2003-09-22 HK HK03106770.0A patent/HK1054334B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE60118914D1 (de)	2006-05-24
JP2003535890A (ja)	2003-12-02
NO329783B1 (no)	2010-12-13
KR100853955B1 (ko)	2008-08-25
BR0111813A (pt)	2003-05-20
AU7846301A (en)	2002-01-02
CZ20024155A3 (cs)	2003-04-16
ES2261448T3 (es)	2006-11-16
GB0015444D0 (en)	2000-08-16
DE60118914T2 (de)	2006-12-21
EE05319B1 (et)	2010-08-16
AU2001278463B2 (en)	2006-02-23
NO20026078D0 (no)	2002-12-18
HK1054334A1 (en)	2003-11-28
EP1292290A2 (en)	2003-03-19
HUP0301257A2 (hu)	2003-08-28
CA2411172A1 (en)	2001-12-27
DK1292290T3 (da)	2006-07-10
SK287549B6 (sk)	2011-01-04
ZA200209834B (en)	2003-12-04
US20030162722A1 (en)	2003-08-28
HK1054334B (zh)	2006-09-22
EA200300060A1 (ru)	2003-04-24
SK18332002A3 (sk)	2003-07-01
NO20026078L (no)	2002-12-18
CN1437474A (zh)	2003-08-20
MXPA02012163A (es)	2003-04-25
WO2001097789A2 (en)	2001-12-27
EE200200681A (et)	2004-06-15
CA2411172C (en)	2009-11-17
WO2001097789A3 (en)	2002-05-16
NZ523000A (en)	2005-12-23
EA006684B1 (ru)	2006-02-24
EP1292290B1 (en)	2006-04-19
KR20030019448A (ko)	2003-03-06
CN1241573C (zh)	2006-02-15
PL200503B1 (pl)	2009-01-30
ATE323483T1 (de)	2006-05-15
PT1292290E (pt)	2006-08-31
IL153177A0 (en)	2003-06-24

Publication	Publication Date	Title
HK1054334A1 (en)	2003-11-28	Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase i and ii inhibitors
CY1106713T1 (el)	2012-05-23	Συνδυασμενη θεραπεια εναντιον καρκινωματων η οποια περιλαμβανει παραγωγα υποκαταστημενης ακρυλοϋλ δισταμυσινης και αλκυλιωτικους παραγοντες
MXPA03004023A (es)	2004-02-12	Compuestos quimicos.
MXPA02012165A (es)	2003-04-25	Terapia combinada contra tumores que comprende derivados de acriloil-distamicina sustituida, taxanos y/o antimetabolitos.
IL162820A0 (en)	2005-11-20	Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and protein kinase (serine/threonine kinase) inhibitors

Legal Events

Date	Code	Title	Description
2012-08-31	LAPS	Decisions on the lapse of the protection rights	Effective date: 20110620