PL3325443T3 - Sposób otrzymywania pridopidyny - Google Patents
Sposób otrzymywania pridopidynyInfo
- Publication number
- PL3325443T3 PL3325443T3 PL16828644.1T PL16828644T PL3325443T3 PL 3325443 T3 PL3325443 T3 PL 3325443T3 PL 16828644 T PL16828644 T PL 16828644T PL 3325443 T3 PL3325443 T3 PL 3325443T3
- Authority
- PL
- Poland
- Prior art keywords
- pridopidine
- preparing
- preparing pridopidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/24—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by sulfur atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562195756P | 2015-07-22 | 2015-07-22 | |
| PCT/US2016/043682 WO2017015609A1 (en) | 2015-07-22 | 2016-07-22 | Process for preparing pridopidine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3325443T3 true PL3325443T3 (pl) | 2022-08-01 |
Family
ID=57834816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL16828644.1T PL3325443T3 (pl) | 2015-07-22 | 2016-07-22 | Sposób otrzymywania pridopidyny |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10047049B2 (pl) |
| EP (1) | EP3325443B1 (pl) |
| AR (1) | AR105434A1 (pl) |
| CA (1) | CA2993607C (pl) |
| DK (1) | DK3325443T3 (pl) |
| ES (1) | ES2922991T3 (pl) |
| HU (1) | HUE059158T2 (pl) |
| PL (1) | PL3325443T3 (pl) |
| TW (1) | TW201718491A (pl) |
| WO (1) | WO2017015609A1 (pl) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20140008297A (ko) | 2010-09-03 | 2014-01-21 | 아이백스 인터내셔널 게엠베하 | 도파민성 안정제로서 유용한 프리도피딘의 듀테륨화된 유사체 |
| TWI579272B (zh) | 2011-12-08 | 2017-04-21 | 梯瓦製藥國際有限責任公司 | 普多比啶（ｐｒｉｄｏｐｉｄｉｎｅ）之氫溴酸鹽 |
| CN105592848A (zh) | 2013-06-21 | 2016-05-18 | 梯瓦制药国际有限责任公司 | 高剂量普利多匹定用于治疗亨廷顿舞蹈症的用途 |
| US11090297B2 (en) | 2013-06-21 | 2021-08-17 | Prilenia Neurotherapeutics Ltd. | Pridopidine for treating huntington's disease |
| TW201613859A (en) | 2014-06-30 | 2016-04-16 | Teva Pharma | Analogs of PRIDOPIDINE, their preparation and use |
| US9907786B2 (en) * | 2014-10-21 | 2018-03-06 | Ions Pharmaceutical S.À R.L. | Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof |
| US11471449B2 (en) | 2015-02-25 | 2022-10-18 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine to improve cognitive function and for treating Alzheimer's disease |
| DK3261721T3 (da) | 2015-02-25 | 2022-11-28 | Prilenia Neurotherapeutics Ltd | Anvendelse af pridopidin til forbedring af hukommelse |
| JP7034488B2 (ja) | 2016-02-24 | 2022-03-14 | プリレニア・ニューロセラピューティクス・エルティーディー | プリドピジンを使用する神経変性眼疾患の治療 |
| CN109923102B (zh) | 2016-08-24 | 2022-11-15 | 普瑞尼亚神经治疗有限公司 | 普利多匹定用于治疗功能下降的用途 |
| WO2018039475A1 (en) | 2016-08-24 | 2018-03-01 | Teva Pharmaceuticals International Gmbh | Use of pridopidine for treating dystonias |
| US12102627B2 (en) | 2016-09-16 | 2024-10-01 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine for treating rett syndrome |
| EP3357909A1 (en) * | 2017-02-02 | 2018-08-08 | Sandoz AG | Crystalline 4-[3-(methylsulfonyl)phenyl]-1-propyl-piperidine |
| BR112020003119A2 (pt) | 2017-08-14 | 2020-10-13 | Prilenia Neurotherapeutics Ltd. | método de tratamento de esclerose lateral amiotrófica com pridopidina |
| EP3675830A1 (en) | 2017-08-30 | 2020-07-08 | Prilenia Neurotherapeutics Ltd. | High concentration dosage forms of pridopidine |
| US12036213B2 (en) | 2017-09-08 | 2024-07-16 | Prilenia Neurotherapeutics Ltd. | Pridopidine for treating drug induced dyskinesias |
| BR112020004622A2 (pt) | 2017-09-08 | 2020-09-24 | Prilenia Neurotherapeutics Ltd. | pridopidina para tratamento de discinesias induzidas por droga |
| US12129265B2 (en) | 2020-07-21 | 2024-10-29 | Ankh Life Sciences Limited | Therapeutic agents and uses thereof |
| CN119137100A (zh) * | 2022-05-03 | 2024-12-13 | 普瑞尼亚神经治疗有限公司 | 用于制备普利多匹定的工艺和中间体 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0641320B1 (en) | 1991-04-17 | 2001-05-30 | PHARMACIA & UPJOHN COMPANY | Substituted (s)-3-phenylpiperidine derivatives, their preparation and their use as dopamine autoreceptor antagonists |
| SE9702716D0 (sv) | 1997-07-15 | 1997-07-15 | Ross Nicholas Waters | Substituted phenylazacycloalkanes in the treatment of cognitive disorders |
| SE9904724D0 (sv) | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission I |
| USRE46117E1 (en) | 1999-12-22 | 2016-08-23 | Teva Pharmaceuticals International Gmbh | Modulators of dopamine neurotransmission |
| SE9904723D0 (sv) | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission II |
| JP4891908B2 (ja) * | 2004-10-13 | 2012-03-07 | エヌエスエービー，フィリアル アフ ニューロサーチ スウェーデン アクチボラゲット，スヴェリエ | ４−（３−メタンスルホニルフェニル）−１−ｎ−プロピルピペリジンの合成方法 |
| EP1807394A1 (en) | 2004-10-13 | 2007-07-18 | Neurosearch Sweden AB | Process for the synthesis of 4-(3-sulfonylphenyl)-piperidines |
| CA2683719C (en) | 2007-04-12 | 2015-07-14 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | N-oxide and/or di-n-oxide derivatives of dopamine receptor stabilizers/modulators displaying improved cardiovascular side-effects profiles |
| WO2011107583A1 (en) * | 2010-03-04 | 2011-09-09 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Substituted 4-phenyl-n-alkyl-piperidines for preventing onset or slowing progression of neurodegenerative disorders |
| KR20140008297A (ko) * | 2010-09-03 | 2014-01-21 | 아이백스 인터내셔널 게엠베하 | 도파민성 안정제로서 유용한 프리도피딘의 듀테륨화된 유사체 |
| CN103958469B (zh) * | 2011-09-07 | 2016-04-20 | 梯瓦制药国际有限责任公司 | 一种新的普利多匹定盐酸盐多晶型形态 |
| TWI579272B (zh) * | 2011-12-08 | 2017-04-21 | 梯瓦製藥國際有限責任公司 | 普多比啶（ｐｒｉｄｏｐｉｄｉｎｅ）之氫溴酸鹽 |
| BR112014024672A8 (pt) | 2012-04-04 | 2018-04-03 | Ivax Int Gmbh | Composições farmacêuticas para terapia de combinação |
| AU2013323131A1 (en) | 2012-09-27 | 2015-05-07 | Teva Pharmaceutical Industries Ltd. | Laquinimod and pridopidine for treating neurodegenerative disorders |
| MX2015003812A (es) | 2012-09-27 | 2015-07-17 | Teva Pharma | Combinacion de rasagilina y pridopidina para tratar trastornos neurodegenerativos, en particular enfermedad de huntington. |
| CN105592848A (zh) | 2013-06-21 | 2016-05-18 | 梯瓦制药国际有限责任公司 | 高剂量普利多匹定用于治疗亨廷顿舞蹈症的用途 |
| MX2016009427A (es) | 2014-01-22 | 2016-12-08 | Teva Pharmaceuticals Int Gmbh | Formulaciones de pridopidina de liberacion modificada. |
| TW201613859A (en) | 2014-06-30 | 2016-04-16 | Teva Pharma | Analogs of PRIDOPIDINE, their preparation and use |
| EP3236964A4 (en) | 2014-12-22 | 2018-09-19 | Teva Pharmaceuticals International GmbH | L-tartrate salt of pridopidine |
| DK3261721T3 (da) | 2015-02-25 | 2022-11-28 | Prilenia Neurotherapeutics Ltd | Anvendelse af pridopidin til forbedring af hukommelse |
| WO2016138135A1 (en) | 2015-02-25 | 2016-09-01 | Teva Pharmaceuticals International Gmbh | Sigma-1 receptor modulators for treating huntington's disease |
| CA2993183A1 (en) | 2015-07-22 | 2017-01-26 | Teva Pharmaceuticals International Gmbh | Pridopidine base formulations and their use |
-
2016
- 2016-07-21 AR ARP160102219A patent/AR105434A1/es active IP Right Grant
- 2016-07-22 TW TW105123329A patent/TW201718491A/zh unknown
- 2016-07-22 DK DK16828644.1T patent/DK3325443T3/da active
- 2016-07-22 US US15/217,683 patent/US10047049B2/en active Active
- 2016-07-22 ES ES16828644T patent/ES2922991T3/es active Active
- 2016-07-22 EP EP16828644.1A patent/EP3325443B1/en active Active
- 2016-07-22 HU HUE16828644A patent/HUE059158T2/hu unknown
- 2016-07-22 PL PL16828644.1T patent/PL3325443T3/pl unknown
- 2016-07-22 WO PCT/US2016/043682 patent/WO2017015609A1/en active Application Filing
- 2016-07-22 CA CA2993607A patent/CA2993607C/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AR105434A1 (es) | 2017-10-04 |
| EP3325443B1 (en) | 2022-06-08 |
| WO2017015609A1 (en) | 2017-01-26 |
| EP3325443A4 (en) | 2019-01-16 |
| CA2993607A1 (en) | 2017-01-26 |
| TW201718491A (zh) | 2017-06-01 |
| DK3325443T3 (da) | 2022-07-18 |
| CA2993607C (en) | 2024-01-16 |
| US10047049B2 (en) | 2018-08-14 |
| ES2922991T3 (es) | 2022-09-22 |
| HUE059158T2 (hu) | 2022-10-28 |
| EP3325443A1 (en) | 2018-05-30 |
| US20170022158A1 (en) | 2017-01-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ZA201708142B (en) | Process for preparing 4-amino-pyridazines | |
| PL3325443T3 (pl) | Sposób otrzymywania pridopidyny | |
| IL249730B (en) | A process for the preparation of pyrazoles | |
| IL274439A (en) | Process for making Tapinaroff | |
| PT3196196T (pt) | Método para a preparação de calcobutrol | |
| PL3371150T3 (pl) | Sposób wytwarzania briwaracetamu | |
| HK1247097A1 (zh) | 用於製備氟酮內酯的方法 | |
| IL253877B (en) | Process for the preparation of 3-chloro-2-vinylphenylsulfonates | |
| PL3160984T3 (pl) | Sposób wytwarzania d-arginylo-2,6-dimetylo-l-tyrozylo-l-lizylol- fenyloalaninoamidu | |
| ZA201908452B (en) | Improved process for preparing imetelstat | |
| GB2536979B (en) | Process for preparing boscalid | |
| PL3156381T3 (pl) | Sposób wytwarzania granulek | |
| IL249283B (en) | Process for the preparation of 3-chloro-2-vinylphenol | |
| GB2539022B (en) | Process for preparing boscalid | |
| PL3113919T3 (pl) | Sposób powlekania fragmentu powierzchni | |
| ZA201807441B (en) | Process for preparing oxathiazin-like compounds | |
| ZA201803631B (en) | Improved process for making crotonylaminopyridines | |
| IL253630B (en) | A process for the preparation of modified phenylisoxazoline derivatives | |
| IL253830B (en) | Process for the preparation of piperidine-4-carbothioamide hydrochloride | |
| SG11201709830YA (en) | Process for preparing carbazoles |