[go: up one dir, main page]

PL2794635T3 - Membranowa chromatografia jonowymienna - Google Patents

Membranowa chromatografia jonowymienna

Info

Publication number
PL2794635T3
PL2794635T3 PL12806322T PL12806322T PL2794635T3 PL 2794635 T3 PL2794635 T3 PL 2794635T3 PL 12806322 T PL12806322 T PL 12806322T PL 12806322 T PL12806322 T PL 12806322T PL 2794635 T3 PL2794635 T3 PL 2794635T3
Authority
PL
Poland
Prior art keywords
ion exchange
exchange membrane
membrane chromatography
chromatography
ion
Prior art date
Application number
PL12806322T
Other languages
English (en)
Inventor
Jerome Joseph Bill Jr.
Arick Michael BROWN
Christopher John Dowd
Brooke Ellen Thayer
Original Assignee
F.Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47430154&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2794635(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by F.Hoffmann-La Roche Ag filed Critical F.Hoffmann-La Roche Ag
Publication of PL2794635T3 publication Critical patent/PL2794635T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/165—Extraction; Separation; Purification by chromatography mixed-mode chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
PL12806322T 2011-12-22 2012-12-18 Membranowa chromatografia jonowymienna PL2794635T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161579285P 2011-12-22 2011-12-22
PCT/US2012/070373 WO2013096322A1 (en) 2011-12-22 2012-12-18 Ion exchange membrane chromatography
EP12806322.9A EP2794635B8 (en) 2011-12-22 2012-12-18 Ion exchange membrane chromatography

Publications (1)

Publication Number Publication Date
PL2794635T3 true PL2794635T3 (pl) 2019-02-28

Family

ID=47430154

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12806322T PL2794635T3 (pl) 2011-12-22 2012-12-18 Membranowa chromatografia jonowymienna

Country Status (21)

Country Link
US (3) US10364268B2 (pl)
EP (2) EP3492486A1 (pl)
JP (5) JP6605202B2 (pl)
KR (3) KR20210025692A (pl)
CN (2) CN108892706A (pl)
AR (1) AR089362A1 (pl)
AU (3) AU2012355356B2 (pl)
BR (1) BR112014015101A8 (pl)
CA (1) CA2859376C (pl)
ES (1) ES2697676T3 (pl)
HR (1) HRP20181846T1 (pl)
IL (2) IL267585B (pl)
MX (2) MX360453B (pl)
MY (1) MY172426A (pl)
PL (1) PL2794635T3 (pl)
RU (1) RU2648999C2 (pl)
SG (1) SG11201403437TA (pl)
SI (1) SI2794635T1 (pl)
TR (1) TR201815709T4 (pl)
WO (1) WO2013096322A1 (pl)
ZA (2) ZA201404593B (pl)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3492486A1 (en) 2011-12-22 2019-06-05 F. Hoffmann-La Roche AG Ion exchange membrane chromatography
SG10201804200WA (en) 2013-12-12 2018-07-30 Emd Millipore Corp Protein separations using an acrylamide containing filter
MX2016008498A (es) * 2013-12-27 2016-10-07 Chugai Pharmaceutical Co Ltd Metodo para purificar anticuerpo que tiene bajo punto isoelectrico.
CN104693303B (zh) * 2015-02-28 2018-03-13 苏州金盟生物技术有限公司 一种蛋白制品中的核酸去除方法
FI3334747T3 (fi) 2015-08-13 2023-11-30 Amgen Inc Antigeenia sitovien proteiinien varattu syväsuodatus
GB201711481D0 (en) 2017-07-17 2017-08-30 Ucb Biopharma Sprl Protein purification
EP3546475A1 (en) * 2018-03-27 2019-10-02 Sanofi Full flow-through process for purifying recombinant proteins
US10792618B2 (en) 2018-06-19 2020-10-06 Sartorius Stedim Biotech Gmbh Particle separation and/or purification of a fluid
KR102140531B1 (ko) * 2018-08-07 2020-08-04 (주)휴온스 Gly-Tβ4의 제조방법
US12103949B2 (en) * 2018-08-14 2024-10-01 Bristol-Myers Squibb Company Protein recovery
GB201815405D0 (en) * 2018-09-21 2018-11-07 Fujifilm Mfg Europe Bv Membranes suitable for detecting, filtering and/or purifying biomolecules
WO2020128797A1 (en) * 2018-12-21 2020-06-25 3M Innovative Properties Company Method for testing a chromatography device used for ion exchange
AR119264A1 (es) * 2019-06-05 2021-12-09 Genentech Inc Método para reutilización de cromatografía
IL294901A (en) * 2020-01-24 2022-09-01 Alkermes Pharma Ireland Ltd Methods of purification
US11416468B2 (en) * 2020-07-21 2022-08-16 International Business Machines Corporation Active-active system index management
CN116371011B (zh) * 2023-05-26 2023-08-18 湖南杰萃生物技术有限公司 一种从桑叶中提取黄酮和生物碱的方法
CN117866038B (zh) * 2024-03-11 2024-05-28 北京百力格生物科技有限公司 纯化含有宿主核酸的带亲和标签的酸性蛋白的方法

Family Cites Families (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE266710C (pl)
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
USRE30985E (en) 1978-01-01 1982-06-29 Serum-free cell culture media
US4515893A (en) 1979-04-26 1985-05-07 Ortho Pharmaceutical Corporation Hybrid cell line for producing complement-fixing monoclonal antibody to human T cells
US4560655A (en) 1982-12-16 1985-12-24 Immunex Corporation Serum-free cell culture medium and process for making same
US4657866A (en) 1982-12-21 1987-04-14 Sudhir Kumar Serum-free, synthetic, completely chemically defined tissue culture media
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
DD266710A3 (de) 1983-06-06 1989-04-12 Ve Forschungszentrum Biotechnologie Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase
US4767704A (en) 1983-10-07 1988-08-30 Columbia University In The City Of New York Protein-free culture medium
JPS6150925A (ja) 1984-08-17 1986-03-13 Toray Ind Inc 抗原または抗体の精製方法
US4879231A (en) 1984-10-30 1989-11-07 Phillips Petroleum Company Transformation of yeasts of the genus pichia
GB8516415D0 (en) 1985-06-28 1985-07-31 Celltech Ltd Culture of animal cells
US5091178A (en) 1986-02-21 1992-02-25 Oncogen Tumor therapy with biologically active anti-tumor antibodies
US4927762A (en) 1986-04-01 1990-05-22 Cell Enterprises, Inc. Cell culture medium with antioxidant
GB8610600D0 (en) 1986-04-30 1986-06-04 Novo Industri As Transformation of trichoderma
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
WO1989003840A1 (en) * 1987-10-23 1989-05-05 Schering Corporation Method of purifying protein
US5091313A (en) 1988-08-05 1992-02-25 Tanox Biosystems, Inc. Antigenic epitopes of IgE present on B cell but not basophil surface
US5720937A (en) 1988-01-12 1998-02-24 Genentech, Inc. In vivo tumor detection assay
DE68919361T2 (de) 1988-06-21 1995-05-24 Genentech Inc Therapeutische zusammensetzungen für die behandlung von myocard-infarkten.
AU632065B2 (en) 1988-09-23 1992-12-17 Novartis Vaccines And Diagnostics, Inc. Cell culture medium for enhanced cell growth, culture longevity and product expression
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
JP2844346B2 (ja) 1989-05-31 1999-01-06 昭 梶 新規ペプチドならびに新規ｄｎａ
EP0402226A1 (en) 1989-06-06 1990-12-12 Institut National De La Recherche Agronomique Transformation vectors for yeast yarrowia
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
US5122469A (en) 1990-10-03 1992-06-16 Genentech, Inc. Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
ES2193136T3 (es) 1991-08-14 2003-11-01 Genentech Inc Variantes de inmunoglubina para receptores especificos de fc epsilon.
AU3178993A (en) 1991-11-25 1993-06-28 Enzon, Inc. Multivalent antigen-binding proteins
WO1993016185A2 (en) 1992-02-06 1993-08-19 Creative Biomolecules, Inc. Biosynthetic binding protein for cancer marker
EP0656789B1 (en) 1992-08-21 1997-12-17 Genentech, Inc. Method for treating a lfa-1-mediated disorder
US5736137A (en) 1992-11-13 1998-04-07 Idec Pharmaceuticals Corporation Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
US5595721A (en) 1993-09-16 1997-01-21 Coulter Pharmaceutical, Inc. Radioimmunotherapy of lymphoma using anti-CD20
RU2145873C1 (ru) 1993-09-21 2000-02-27 Хемосол Инк. Способ очистки гемоглобина в коммерческом масштабе
ES2108566T3 (es) 1993-12-10 1997-12-16 Genentech Inc Procedimientos para diagnosticar alergias y para seleccionar agentes terapeuticos antialergicos.
EP0739214B1 (en) 1994-01-18 1998-03-18 Genentech, Inc. A METHOD OF TREATMENT OF PARASITIC INFECTION USING IgE ANTAGONISTS
MX9603773A (es) 1994-03-03 1997-07-31 Genentech Inc Anticuerpos monoclonales anti-interleucina-8 para el tratamiento de trastornos inflamatorios.
US5534615A (en) 1994-04-25 1996-07-09 Genentech, Inc. Cardiac hypertrophy factor and uses therefor
IL117645A (en) 1995-03-30 2005-08-31 Genentech Inc Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
CA2222231A1 (en) 1995-06-07 1996-12-19 Imclone Systems Incorporated Antibody and antibody fragments for inhibiting the growth of tumors
JP4864175B2 (ja) 1996-01-23 2012-02-01 ジェネンテック， インコーポレイテッド 発作に関する抗―ｃｄ１８抗体
US6592905B1 (en) 1996-01-31 2003-07-15 Massey University Production of an immunoglobulin enriched fraction from whey protein solutions
US7147851B1 (en) 1996-08-15 2006-12-12 Millennium Pharmaceuticals, Inc. Humanized immunoglobulin reactive with α4β7 integrin
WO1998023761A1 (en) 1996-11-27 1998-06-04 Genentech, Inc. HUMANIZED ANTI-CD11a ANTIBODIES
DE69836729T2 (de) 1997-04-07 2007-12-13 Genentech, Inc., South San Francisco Anti-vefg antibodies
IL132067A0 (en) 1997-05-15 2001-03-19 Genentech Inc Apo-2 receptor
US6054293A (en) 1997-07-08 2000-04-25 The Regents Of The University Of California Semaphorin receptors
US6946129B1 (en) 1999-06-08 2005-09-20 Seattle Genetics, Inc. Recombinant anti-CD40 antibody and uses thereof
WO2001000245A2 (en) 1999-06-25 2001-01-04 Genentech, Inc. HUMANIZED ANTI-ErbB2 ANTIBODIES AND TREATMENT WITH ANTI-ErbB2 ANTIBODIES
KR100490077B1 (ko) 1999-10-29 2005-05-17 제넨테크, 인크. 항-전립선 줄기세포 항원 (ｐｓｃａ) 항체 조성물 및 그의사용 방법
EP1301591A4 (en) 2000-07-13 2004-05-26 Invitrogen Corp METHOD AND COMPOSITIONS FOR QUICK PROTEIN AND PEPTIDE EXTRACTION AND INSULATION USING LYSIS MATRIZE
UA83458C2 (uk) 2000-09-18 2008-07-25 Байоджен Айдек Ма Інк. Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf)
US7321026B2 (en) 2001-06-27 2008-01-22 Skytech Technology Limited Framework-patched immunoglobulins
WO2003025156A2 (en) 2001-09-18 2003-03-27 Affinium Pharmaceuticals, Inc. Methods and apparatuses for purification
WO2003033656A2 (en) 2001-10-16 2003-04-24 Exelixis, Inc. MSREBPs AS MODIFIERS OF THE SREBP PATHWAY AND METHODS OF USE
CA2476675A1 (en) 2001-10-17 2003-04-24 Human Genome Sciences, Inc. Neutrokine-alpha and neutrokine-alpha splice variant
US20040093621A1 (en) 2001-12-25 2004-05-13 Kyowa Hakko Kogyo Co., Ltd Antibody composition which specifically binds to CD20
EP2295468B1 (en) 2002-02-14 2015-07-08 Immunomedics, Inc. Anti-CD20 antibodies and fusion proteins thereof and methods of use
CN1729203B (zh) 2002-10-17 2014-02-19 根马布股份公司 抗cd20的人单克隆抗体
DE60332957D1 (de) 2002-12-16 2010-07-22 Genentech Inc Immunoglobulinvarianten und deren verwendungen
CN1206240C (zh) * 2003-04-07 2005-06-15 中国科学院生态环境研究中心 高效离子交换膜色谱纯化卵黄蛋白原技术
EP2960251A1 (en) 2003-05-09 2015-12-30 Duke University CD20-specific antibodies and methods of employing same
AR044388A1 (es) 2003-05-20 2005-09-07 Applied Molecular Evolution Moleculas de union a cd20
WO2005014618A2 (en) 2003-08-08 2005-02-17 Immunomedics, Inc. Bispecific antibodies for inducing apoptosis of tumor and diseased cells
US8147832B2 (en) 2003-08-14 2012-04-03 Merck Patent Gmbh CD20-binding polypeptide compositions and methods
US20080274501A1 (en) * 2007-05-02 2008-11-06 Chenming Zhang Method of purifying acidic proteins expressed in plants
US9433922B2 (en) 2007-08-14 2016-09-06 Emd Millipore Corporation Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same
US8653246B2 (en) 2007-10-26 2014-02-18 Asahi Kasei Chemicals Corporation Method for purifying protein
SI2215117T2 (en) 2007-10-30 2018-04-30 Genentech, Inc. Purification of the antibody by cation exchange chromatography
WO2009135656A1 (en) * 2008-05-06 2009-11-12 Lonza Biologics Plc. A method for the purification of antibodies using displacement chromatography
AU2008360625C1 (en) * 2008-08-14 2017-01-19 Genentech, Inc. Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography
GB0816242D0 (en) 2008-09-05 2008-10-15 Immunobiology Ltd Method of purifying protien complexes
AU2010292897B2 (en) 2009-08-06 2016-01-07 Genentech, Inc. Method to improve virus removal in protein purification
CN102686738A (zh) * 2009-09-01 2012-09-19 弗·哈夫曼-拉罗切有限公司 通过改进的a蛋白洗脱增强的蛋白质纯化
KR101860963B1 (ko) * 2010-04-23 2018-05-24 제넨테크, 인크. 이종다량체 단백질의 생산
HRP20241463T1 (hr) * 2010-05-25 2025-01-03 F. Hoffmann - La Roche Ag Metode pročišćavanja polipeptida
CA2850728A1 (en) * 2011-10-03 2013-04-11 Sachem, Inc. Neutral zwitterionic displacer molecules for hydrophobic displacement chromatography
EP3492486A1 (en) * 2011-12-22 2019-06-05 F. Hoffmann-La Roche AG Ion exchange membrane chromatography
JP5731726B1 (ja) 2014-06-26 2015-06-10 楽天株式会社 情報処理装置、情報処理方法及び情報処理プログラム

Also Published As

Publication number Publication date
US20140348845A1 (en) 2014-11-27
AR089362A1 (es) 2014-08-20
HK1203526A1 (en) 2015-10-30
JP2015503524A (ja) 2015-02-02
BR112014015101A2 (pt) 2017-06-13
WO2013096322A1 (en) 2013-06-27
JP7359807B2 (ja) 2023-10-11
KR20210025692A (ko) 2021-03-09
MX2018013356A (es) 2020-09-14
EP2794635B1 (en) 2018-09-12
HRP20181846T1 (hr) 2018-12-28
IL267585A (en) 2019-08-29
SI2794635T1 (sl) 2018-12-31
TR201815709T4 (tr) 2018-11-21
AU2012355356B2 (en) 2017-10-12
RU2648999C2 (ru) 2018-03-29
IL267585B (en) 2022-09-01
JP7402011B2 (ja) 2023-12-20
WO2013096322A8 (en) 2014-02-27
AU2020201070A1 (en) 2020-03-05
AU2018200194B2 (en) 2019-11-14
ZA201404593B (en) 2022-12-21
AU2018200194A1 (en) 2018-02-01
MX2014007622A (es) 2014-09-22
US10364268B2 (en) 2019-07-30
WO2013096322A9 (en) 2013-08-22
CN104125963A (zh) 2014-10-29
ZA201903994B (en) 2023-12-20
RU2014130017A (ru) 2016-02-10
US20240247027A1 (en) 2024-07-25
EP3492486A1 (en) 2019-06-05
JP2021169454A (ja) 2021-10-28
JP2022101557A (ja) 2022-07-06
CN108892706A (zh) 2018-11-27
US11945837B2 (en) 2024-04-02
JP2020040952A (ja) 2020-03-19
NZ626949A (en) 2016-11-25
BR112014015101A8 (pt) 2021-06-08
SG11201403437TA (en) 2014-07-30
CA2859376C (en) 2022-04-19
CA2859376A1 (en) 2013-06-27
AU2012355356A1 (en) 2014-07-10
US20200102346A1 (en) 2020-04-02
KR102067075B1 (ko) 2020-01-17
KR20140114834A (ko) 2014-09-29
CN104125963B (zh) 2018-08-17
KR20200008022A (ko) 2020-01-22
JP2018109024A (ja) 2018-07-12
IL233158B (en) 2019-07-31
EP2794635B8 (en) 2018-11-14
IL233158A0 (en) 2014-07-31
JP6605202B2 (ja) 2019-11-13
MX360453B (es) 2018-11-01
ES2697676T3 (es) 2019-01-25
EP2794635A1 (en) 2014-10-29
MY172426A (en) 2019-11-25

Similar Documents

Publication Publication Date Title
IL267585A (en) Ion exchange membrane chromatography
PL2734473T3 (pl) Związki typu granatu przewodzące jony litu
GB201107849D0 (en) Cooperative positioning
EP2667919A4 (en) Humidifier
AP2013007300A0 (en) Fused benzoxazepinones as ion modulators
EP2920586A4 (en) IONIC STRENGTH-MEDIATED pH GRADIENT ION EXCHANGE CHROMATOGRAPHY
IL238131B (en) Coated membranes for ion exchange
EP2692782A4 (en) ION EXCHANGE MEMBRANE
EP2698839A4 (en) BLOCK OF CELLS
EP2707886A4 (en) ELECTROLYTE
IL225720A0 (en) Antibody purification in one ion exchange chromatography unit
GB2532391B (en) Diaphragm
EP2711340A4 (en) ION EXCHANGER EQUIPMENT
GB201102347D0 (en) Positioning system
EP2709203A4 (en) CELL SYSTEM
GB201118288D0 (en) Ion-conducting membrane
SG11201501151TA (en) Methods for manufacturing ion exchange membranes
GB201109281D0 (en) Membrane
EP2787567A4 (en) FUEL CELL SYSTEM
GB2494304B (en) Spacer
SG11201400765SA (en) Electrochemical processor alignment system
GB2499313B (en) Ion exchange
ZA201102777B (en) Spacer
GB201120948D0 (en) Flooring membrane
GB201109603D0 (en) Spacer for multi-glazed units