PL141641B1 - Agent for fighting against and/or preventing paralyzing effects of microorganisms and method of obtaining new derivatives of n-/2-nitrophenylo/-4-aminopyrimidiines - Google Patents
Agent for fighting against and/or preventing paralyzing effects of microorganisms and method of obtaining new derivatives of n-/2-nitrophenylo/-4-aminopyrimidiines Download PDFInfo
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- PL141641B1 PL141641B1 PL1984247096A PL24709684A PL141641B1 PL 141641 B1 PL141641 B1 PL 141641B1 PL 1984247096 A PL1984247096 A PL 1984247096A PL 24709684 A PL24709684 A PL 24709684A PL 141641 B1 PL141641 B1 PL 141641B1
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/56—One oxygen atom and one sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/58—Two sulfur atoms
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Pest Control & Pesticides (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Carbon And Carbon Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Description
Przedmiotem wynalazkujest srodek do zwalczania lub zapobiegania porazeniu przez mikro¬ organizmy, zwierajacy znane nosniki i/lub substancje pomocnicze oraz substancje czynna, a takze sposób wytwarzania nowych pochodnych N-/2-nitrofenylo/-4-aminopirymidyny.Srodek wedlug wynalazku zawiera jako substancje czynna co najmniej jedna nowa pochodna N-/2-nitrofenylo/-4-aminopirymidyny o ogólnym wzorze 1, w którym Ri oznacza grupe nitrowa lub grupe trójfluorometylowa, R2 oznacza grupe nitrowa lub grupe trójfluorometylowa, R3 ozna¬ cza atom wodoru lub chlorowca, R4 oznacza atom wodoru lub grupe -C/O/R7, przy czym R7 stanowi ewentualnie podstawiony chlorowcem, grupa alkoksylowa o 1-3 atomach wegla lub grupa alkilotio o 1-3 atomach wegla rodnik alkilowy o 1-4 atomach wegla, R5 i Re niezaleznie od siebie oznaczaja atom chlorowca, podstawiony chlorowcem lub grupa alkoksylowa o 1-3 atomach wegla rodnik alkilowy o 1-6 atomach wegla, ewentualnie podstawiona chlorowcem lub rodnikiem alkoksylowym o 1-3 atomach wegla grupe alkoksylowa o 1-6 atomach wegla, ewentualnie podsta¬ wiona chlorowcem lub rodnikiem alkoksylowym o 1-3 atomach wegla grupe alkilotio o 1-6 atomach wegla, grupe cykloalkoksylowa o 3-6 atomach wegla, grupe cykloalkilotio o 3-6 atomach wegla, grupe alkenyloksylowa o 3-6 atomach wegla, grupe alkenylotio o 3-6 atomach wegla, grupe alkinyloksylowa o 3-6 atomach wegla, grupe alkilosulfoksylowa o 1-6 atomach wegla, grupe alkilosulfonylowa o 1-6 atomach wegla, grupe alkilosulfonylowa o 1-6 atomach wegla, grupe alkenylosulfoksylowa o 3-6 atomach wegla, grupe alkenylosulfonylowa o 3-6 atomach wegla, grupe cykloalkilosulfoksylowa o 3-6 atomach wegla lub grupe cykloalkilosulfonylowa o 3-6 atomach wegla.Pod okresleniem rodnika alkilowego samego lub jako skladnika innych podstawników nalezy w zaleznosci od liczby podanych atomów wegla rozumiec nastepujace rodniki: metylowy, etylowy, propylowy, butylowy, pentylowy, heksylowy, itp., oraz ich izomery, takie jak rodnik izopropy¬ lowy, izobutylowy, Ill-rz. -butylowy, izopentylowy itd. Rodnik alkenylowy oznacza np. rodnik winylowy, propenyl-/l/-owy, alliiowy.butenyl-/l/-owy, butenyl-/2/-owy, butenyl-/3/-owy itd.. oraz rodniki z lancuchami o kilku wiazaniach podwójnych. Rodnik alkinylowy oznacza np. rodnik2 141641 pr PL
Claims (4)
1. Zastrzezenia patent o we 1. Srodek do zwalczania lub zapobiegania porazeniu przez mikroorganizmy, zawierajacy znane nosniki i/lub substancje pomocnicze oraz substancje czynna, znamienny tym, ze zawierajako substancje czynna co najmniej jedna nowa pochodna N-/2-nitrofenylo/-4-aminopirydyny o ogól¬ nym wzorze 1, w którym Ri oznacza grupe nitrowa lub grupe trójfluorometylowa, R2 oznacza grupe nitrowa lub trójfluorometylowa, R3 oznacza atom wodoru lub chlorowca, R4 oznacza atom wodoru lub grupe -C/O/R7, przy czym R7 stanowi ewentualnie podstawiony chlorowcem, grupa alkoksylowa o 1-3 atomach wegla lub grupa alkilotio o 1-3 atomach wegla rodnik alkilowy o 1-4 atomach wegla, R5 i R6 niezaleznie od siebie oznaczaja atom chlorowca, podstawiony chlorowcem lub grupa alkoksylowa o 1-3 atomach wegla rodnik alkilowy o 1-6 atomach wegla, ewentualnie podstawiona chlorowcem lub rodnikiem alkoksylowym o 1-3 atomach wegla grupe alkoksylowa o 1-6 atomach wegla, ewentualnie podstawiona chlorowcem lub rodnikiem alkoksylowym o 1-3 atomach wegla grupe alkilotio o 1-6 atomach wegla, grupe cykloalkoksylowa o 3-6 atomach wegla, grupe cykloalkilotio o 3-6 atomach wegla, grupe alkenyloksylowa o 3-6 atomach wegla, grupe alkenylotio o 3-6 atomach wegla, grupe alkinyloksylowa o 3-6 atomach wegla, grupe alkilosulfoksy- lowa o 1-6 atomach wegla, grupe alkilosulfonylowa o 1-6 atomach wegla, grupe alkilosulfonyloksy- lowa o 1-6 atomach wegla, grupe alkenylosulfoksylowa o 3-6 atomach wegla, grupe alkenylosulfo- nylowa o 3-6 atomach wegla grupe cykloalkilosulfoksylowa o 3-6 ? omach wegla lub grupe cykloalkilosulfonylowa o 3-6 atomach wegla.
2. Srodek wedlug zastrz. 1, znamienny tym, ze zawiera jako substancje czynna co najmniej jeden zwiazek o wzorze 1 ze zbioru, obejmujacego N-/3' -chloro-2',6' -dwunitro-4' -trójfluoromety- lofenylo/ -4-amino-2,6 -dwuchloropirymidyne, N-/2',4'- dwunitro-6' -trójfluorometylofenylo/ -4- amino-2,6 -dwuchloropirymidyne, N-/3'- chloro-2',6' -dwunitro-4'- trójfluorometylofenylo/ -4- amino-6- chloro-2- metylotiopirymidyne, N-/2',6' -dwunitro-4'- trójfluorometylofenylo/ -4-ami- no-6-chloro -2-metylotiopirymidyne, N-/3'- chloro-2',6'-dwunitro -4-trójfluorometylofenylo/ -4- amino-6-chloro- 2-metoksypirymidyne, N-/3'- chloro-2',6- dwunitro-4' -trójfluorometylofenylo/ -4-amino-6- chloro- 2-etoksypirymidyne, N-/3'-chloro-2',6' dwunitro-4' -trójfluorometylofenylo/ 4-amino-6- chloro-2-etylotiopirymidyne, N-/3'-chloro-2', 6'-dwunitro 4'-trójfluorometylofenylo/ 4-amino- 6-chloro-2- H-rz.- butylotiopirymidyne, N-/2',6' -dwunitro-4'- trójfluorometylofenylo/ -4-amino-2,6- dwuchloropirymidyne, N-/2',4' -dwunitro-6' -trójfluorometylofenylo/ -4-amino-2 -metoksy-6- chloropirymidyne, N-/2',4' -dwunitro-6' -trójfluorometylofenylo/ -4-amino- 2-etoksy -6-chloropirymidyne.
3. Srodek wedlug zastrz. 1, znamienny tym, ze zawiera 0,1-99% substancji czynnej o wzorze 1, 99,9-1% stalej lub cieklej substancji dodatkowej i 0-25% substancji powierzchniowo czynnej.
4. Srodek wedlug zastrz. 3, znamienny tym, ze zawiera 0,1-95% substancji czynnej o wzorze 1, 99,8-5% stalej lub cieklej substancji dodatkowej i 0,1-25% substancji powierzchniowo czynnej.16 141 641 *. Sposób wytwarzania nowych pochodnych N-/2-nitrofenylo/-4-aminopirymidyny o ogól¬ nym wzorze 1, w którym Ri oznacza grupe nitrowa lub grupe trójfluorometylowa, R2 oznacza grupe nitrowa lub grupe trójfluorometylowa, R3 oznacza atom wodoru lub chlorowca, R4 oznacza atom wodoru lub grupe -C/O/R7, przy czym R7 stanowi ewentualnie podstawiony chlorowcem, grupa alkoksylowa o 1-3 atomach wegla lub grupa alkilotio o 1-3 atomach wegla rodnik alkilowy o 1 -4 atomach wegla, R5 i R6 niezaleznie od siebie oznaczaja atom chlorowca, podstawiony chlorow¬ cem lub grupa alkoksylowa o 1-3 atomach wegla rodnik alkilowy o 1-6 atomach wegla, ewentualnie podstawiona chlorowcem lub rodnikiem alkoksylowym o 1-3 atomach wegla grupe alkoksylowa o 1-6 atomach wegla, ewentualnie podstawiona chlorowcem lub rodnikiem alkoksylowym o 1-3 atomach wegla grupe alkilotio o 1-6 atomach wegla, grupe cykloalkoksylowa o 3-6 atomach wegla, grupe cykloalkilotio o 3-6 atomach wegla, grupe alkenyloksylowa o 3-6 atomach wegla, grupe alkenylotio o 3-6 atomach wegla, grupe alkinyloksylowa o 3-6 atomach wegla, grupe alkilosulfo- ksylowa o 1-6 atomach wegla, grupe alkilosulfonylowa o 1-6 atomach wegla, grupe alkilosulfony- loksylowa o 1-6 atomach wegla, grupe alkenylosulfoksylowa o 3-6 atomach wegla, grupe alkenylo- sulfonylowa o 3-6 atomach wegla, grupe cykloalkilosulfoksylowa o 3-6 atomach wegla, lub grupe cykloalkilosulfonylowa o 3-6 atomach wegla, znsumeMy tyn, ze zwiazek o wzorze 2, w obecnosci zasady przeksztalca sie droga reakcji z pochodna pirymidyny o wzorze 3 w zwiazek o wzorze 1, który dla wytworzenia pochodnej N-acylowej N-acyluje sie za pomoca reaktywnej pochodnej kwasu karboksylowego o wzorze 4, przy czym podstawniki R1, R2, R3, R4, R5, Rei R7 maja wyzej podane znaczenie, a X i Y oznaczaja grupe NH2 lub atom chlorowca, i w przypadku gdy X oznacza atom chlorowca, to Y oznacza grupe NH2, w przypadku zas gdy X oznacza grupe NH2, to Y oznacza atom chlorowca. N02 R6 R, "s Wzórl Wzór V fizór 3 R7COOH Wzór 4141641 cino2 a no2 a ^=< Wzór 5 no2 a CF3 Cl Wzór 6 a no2 a f3c-^Vnh a\ N02 SCH, Wzór 7 a N02 Hal N=/ M NO 2 Wzór 8 R CH3 0-C-OCH C2H5 Wzór 9 \0Z Hal CF3 ^R Hal F3CA\ // N02 NH NO? Hal; R Wzór II141641, Cl N02 Rb 02 RQ lAJzor 12 Wzór 14 Wzór 15 Pracownia Poligraficzna U? PRL. Naklad 100 egz Cena 220 zl PL PL
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH189983 | 1983-04-08 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL247096A1 PL247096A1 (en) | 1985-03-12 |
| PL141641B1 true PL141641B1 (en) | 1987-08-31 |
Family
ID=4221193
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL1984247096A PL141641B1 (en) | 1983-04-08 | 1984-04-06 | Agent for fighting against and/or preventing paralyzing effects of microorganisms and method of obtaining new derivatives of n-/2-nitrophenylo/-4-aminopyrimidiines |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US4705790A (pl) |
| EP (1) | EP0126254B1 (pl) |
| JP (1) | JPS59205368A (pl) |
| KR (1) | KR840008413A (pl) |
| AT (1) | ATE30721T1 (pl) |
| AU (1) | AU572130B2 (pl) |
| BR (1) | BR8401620A (pl) |
| CA (1) | CA1218369A (pl) |
| CS (1) | CS241078B2 (pl) |
| DD (1) | DD222768A5 (pl) |
| DE (1) | DE3467348D1 (pl) |
| DK (1) | DK130584A (pl) |
| ES (1) | ES531393A0 (pl) |
| FI (1) | FI841301A (pl) |
| GB (1) | GB2137991B (pl) |
| GR (1) | GR79586B (pl) |
| HU (1) | HU198697B (pl) |
| IL (1) | IL71457A (pl) |
| MA (1) | MA20083A1 (pl) |
| NO (1) | NO841386L (pl) |
| NZ (1) | NZ207767A (pl) |
| PH (1) | PH20340A (pl) |
| PL (1) | PL141641B1 (pl) |
| PT (1) | PT78377B (pl) |
| TR (1) | TR22056A (pl) |
| ZA (1) | ZA842574B (pl) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4505910A (en) * | 1983-06-30 | 1985-03-19 | American Home Products Corporation | Amino-pyrimidine derivatives, compositions and use |
| US4659363A (en) * | 1983-07-25 | 1987-04-21 | Ciba-Geigy Corporation | N-(2-nitrophenyl)-2-aminopyrimidine derivatives, the preparation and use thereof |
| ATE60591T1 (de) * | 1984-06-25 | 1991-02-15 | Ciba Geigy Ag | Pyrimidinderivate wirksam als schaedlingsbekaempfungsmittel. |
| DE3618353A1 (de) * | 1986-05-31 | 1987-12-03 | Hoechst Ag | Schaedlingsbekaempfungsmittel auf der basis von aminopyrimidin-derivaten sowie neue aminopyrimidin-verbindungen |
| JPH0784445B2 (ja) * | 1986-12-03 | 1995-09-13 | クミアイ化学工業株式会社 | ピリミジン誘導体および農園芸用殺菌剤 |
| GR900100380A (el) * | 1989-05-20 | 1991-10-10 | Fisons Plc | Μέ?οδος παρασκευής αντι-φλεγμονωδών παραγώγων αμινοφενόλης. |
| EP0445074A1 (de) * | 1990-02-27 | 1991-09-04 | Ciba-Geigy Ag | N-(2,6-Dinitro-3-chlor-4-trifluoromethylphenyl)-4-amino-6-fluorpyrimidin-Derivate und ihre Anwendung als Mikrobizide |
| DE4029648A1 (de) * | 1990-09-19 | 1992-03-26 | Hoechst Ag | 4-anilino-pyrimidine, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als fungizide |
| US5733932A (en) * | 1995-01-06 | 1998-03-31 | The Picower Institute For Medical Research | Compounds and methods of use to derivatize neighboring lysine residues in proteins under physiological conditions |
| US5574040A (en) * | 1995-01-06 | 1996-11-12 | Picower Institute For Medical Research | Pyrimidine compounds and methods of use to derivatize neighboring lysine residues in proteins under physiologic conditions |
| EP1871743A4 (en) * | 2005-04-11 | 2009-12-30 | Univ Murdoch | PEST CONTROL COMPOUNDS |
| US11229746B2 (en) | 2006-06-22 | 2022-01-25 | Excelsior Medical Corporation | Antiseptic cap |
| US9259535B2 (en) | 2006-06-22 | 2016-02-16 | Excelsior Medical Corporation | Antiseptic cap equipped syringe |
| US8622995B2 (en) | 2009-10-26 | 2014-01-07 | Pursuit Vascular, Inc. | Method for delivery of antimicrobial to proximal end of catheter |
| US9022984B2 (en) | 2008-10-27 | 2015-05-05 | Pursuit Vascular, Inc. | Apparatus for delivery of device and antimicrobial agent into trans-dermal catheter |
| US9078992B2 (en) | 2008-10-27 | 2015-07-14 | Pursuit Vascular, Inc. | Medical device for applying antimicrobial to proximal end of catheter |
| US8622996B2 (en) | 2008-10-27 | 2014-01-07 | Pursuit Vascular, Inc. | Method for applying antimicrobial to proximal end of catheter |
| US10166381B2 (en) | 2011-05-23 | 2019-01-01 | Excelsior Medical Corporation | Antiseptic cap |
| EP2731658B1 (en) | 2011-07-12 | 2020-04-01 | Pursuit Vascular, Inc. | Device for delivery of antimicrobial agent into trans-dermal catheter |
| WO2015168677A1 (en) | 2014-05-02 | 2015-11-05 | Excelsior Medical Corporation | Strip package for antiseptic cap |
| US20170280718A1 (en) * | 2014-09-10 | 2017-10-05 | The Regents Of The University Of California | Herbicidal and fungicidal compositions and their uses |
| AU2016262400B2 (en) | 2015-05-08 | 2021-01-21 | Icu Medical, Inc. | Medical connectors configured to receive emitters of therapeutic agents |
| EP4194043A1 (en) | 2016-10-14 | 2023-06-14 | ICU Medical, Inc. | Sanitizing caps for medical connectors |
| WO2018204206A2 (en) | 2017-05-01 | 2018-11-08 | Icu Medical, Inc. | Medical fluid connectors and methods for providing additives in medical fluid lines |
| US11400195B2 (en) | 2018-11-07 | 2022-08-02 | Icu Medical, Inc. | Peritoneal dialysis transfer set with antimicrobial properties |
| US11534595B2 (en) | 2018-11-07 | 2022-12-27 | Icu Medical, Inc. | Device for delivering an antimicrobial composition into an infusion device |
| US10525250B1 (en) | 2018-11-07 | 2020-01-07 | Pursuit Vascular, Inc. | Infusion device with antimicrobial properties |
| US11517732B2 (en) | 2018-11-07 | 2022-12-06 | Icu Medical, Inc. | Syringe with antimicrobial properties |
| US11541220B2 (en) | 2018-11-07 | 2023-01-03 | Icu Medical, Inc. | Needleless connector with antimicrobial properties |
| US11541221B2 (en) | 2018-11-07 | 2023-01-03 | Icu Medical, Inc. | Tubing set with antimicrobial properties |
| WO2020106985A1 (en) | 2018-11-21 | 2020-05-28 | Pursuit Vascular, Inc. | Antimicrobial device comprising a cap with ring and insert |
| JP2024500319A (ja) | 2020-12-07 | 2024-01-09 | アイシーユー・メディカル・インコーポレーテッド | 腹膜透析キャップ、システム、及び方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1394816A (en) * | 1971-03-19 | 1975-05-21 | Ici Ltd | Substituted amino diazinyl compounds and pesticidal compositions thereof |
| GB1388825A (en) * | 1971-03-19 | 1975-03-26 | Ici Ltd | Substituted amino pyrimidine compounds and pesticidal compo sitions thereof |
| JPS57203072A (en) * | 1981-06-05 | 1982-12-13 | Sankyo Co Ltd | 4-anilinopyrimidine derivative, its preparation, antidepressant comprising it as active ingredient |
| IT1211096B (it) * | 1981-08-20 | 1989-09-29 | Lpb Ist Farm | Pirimidine e s.triazinici adattivita' ipolipidemizzante. |
-
1984
- 1984-02-29 DK DK130584A patent/DK130584A/da not_active Application Discontinuation
- 1984-04-02 MA MA20304A patent/MA20083A1/fr unknown
- 1984-04-02 FI FI841301A patent/FI841301A/fi not_active Application Discontinuation
- 1984-04-02 GB GB08408407A patent/GB2137991B/en not_active Expired
- 1984-04-04 CS CS842604A patent/CS241078B2/cs unknown
- 1984-04-05 AT AT84103804T patent/ATE30721T1/de not_active IP Right Cessation
- 1984-04-05 DD DD84261680A patent/DD222768A5/de not_active IP Right Cessation
- 1984-04-05 EP EP84103804A patent/EP0126254B1/de not_active Expired
- 1984-04-05 ZA ZA842574A patent/ZA842574B/xx unknown
- 1984-04-05 DE DE8484103804T patent/DE3467348D1/de not_active Expired
- 1984-04-05 PH PH30504A patent/PH20340A/en unknown
- 1984-04-06 HU HU841355A patent/HU198697B/hu not_active IP Right Cessation
- 1984-04-06 PL PL1984247096A patent/PL141641B1/pl unknown
- 1984-04-06 IL IL71457A patent/IL71457A/xx unknown
- 1984-04-06 GR GR74339A patent/GR79586B/el unknown
- 1984-04-06 CA CA000451480A patent/CA1218369A/en not_active Expired
- 1984-04-06 TR TR22056A patent/TR22056A/xx unknown
- 1984-04-06 NO NO841386A patent/NO841386L/no unknown
- 1984-04-06 PT PT78377A patent/PT78377B/pt unknown
- 1984-04-06 NZ NZ207767A patent/NZ207767A/en unknown
- 1984-04-06 AU AU26604/84A patent/AU572130B2/en not_active Ceased
- 1984-04-06 BR BR8401620A patent/BR8401620A/pt unknown
- 1984-04-07 JP JP59069888A patent/JPS59205368A/ja active Pending
- 1984-04-07 KR KR1019840001838A patent/KR840008413A/ko not_active Application Discontinuation
- 1984-04-07 ES ES531393A patent/ES531393A0/es active Granted
-
1985
- 1985-09-25 US US06/780,063 patent/US4705790A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ZA842574B (en) | 1984-12-24 |
| US4705790A (en) | 1987-11-10 |
| GB8408407D0 (en) | 1984-05-10 |
| ES8505970A1 (es) | 1985-06-16 |
| IL71457A (en) | 1988-01-31 |
| PH20340A (en) | 1986-12-04 |
| DD222768A5 (de) | 1985-05-29 |
| HUT34455A (en) | 1985-03-28 |
| DK130584D0 (da) | 1984-02-29 |
| KR840008413A (ko) | 1984-12-15 |
| BR8401620A (pt) | 1984-11-13 |
| EP0126254B1 (de) | 1987-11-11 |
| DK130584A (da) | 1984-10-09 |
| CS241078B2 (en) | 1986-03-13 |
| ATE30721T1 (de) | 1987-11-15 |
| CA1218369A (en) | 1987-02-24 |
| PT78377A (en) | 1984-05-01 |
| PL247096A1 (en) | 1985-03-12 |
| ES531393A0 (es) | 1985-06-16 |
| PT78377B (en) | 1986-08-14 |
| GR79586B (pl) | 1984-10-30 |
| AU572130B2 (en) | 1988-05-05 |
| GB2137991B (en) | 1986-11-19 |
| HU198697B (en) | 1989-11-28 |
| TR22056A (tr) | 1986-02-18 |
| DE3467348D1 (de) | 1987-12-17 |
| NO841386L (no) | 1984-10-09 |
| JPS59205368A (ja) | 1984-11-20 |
| FI841301A (fi) | 1984-10-09 |
| IL71457A0 (en) | 1984-07-31 |
| NZ207767A (en) | 1987-07-31 |
| GB2137991A (en) | 1984-10-17 |
| MA20083A1 (fr) | 1984-12-31 |
| EP0126254A1 (de) | 1984-11-28 |
| FI841301A0 (fi) | 1984-04-02 |
| AU2660484A (en) | 1984-10-11 |
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