PH14663A - 1-n-hydroxyalkyl derivatives of aminoclycoside antibiotics and their use as antibacterial agents - Google Patents

1-n-hydroxyalkyl derivatives of aminoclycoside antibiotics and their use as antibacterial agents

Info

Publication number: PH14663A
Authority: PH; Philippines
Prior art keywords: aminoclycoside; antibiotics; antibacterial agents; hydroxyalkyl derivatives; hydroxyalkyl
Prior art date: 1976-06-16

Application number

PH19833A

Other languages

English (en)

Inventor

Kenneth Richardson

Rhona Margaret Plews

James Robert Wright

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-06-16

Filing date

1977-05-31

Publication date

1981-10-20

1976-06-16 Priority claimed from GB24989/76A external-priority patent/GB1530202A/en

1977-05-31 Application filed by Pfizer filed Critical Pfizer

1981-10-20 Publication of PH14663A publication Critical patent/PH14663A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Oncology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Communicable Diseases (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PH19833A 1976-06-16 1977-05-31 1-n-hydroxyalkyl derivatives of aminoclycoside antibiotics and their use as antibacterial agents PH14663A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB24989/76A GB1530202A (en)	1976-06-16	1976-06-16	Aminoglycosides
GB4014576		1976-09-28
GB5129476		1976-12-08

Publications (1)

Publication Number	Publication Date
PH14663A true PH14663A (en)	1981-10-20

Family

ID=27258386

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH19833A PH14663A (en)	1976-06-16	1977-05-31	1-n-hydroxyalkyl derivatives of aminoclycoside antibiotics and their use as antibacterial agents

Country Status (31)

Country	Link
US (1)	US4214074A (xx)
JP (1)	JPS52153943A (xx)
AR (1)	AR222781A1 (xx)
AT (1)	AT350722B (xx)
BG (1)	BG28071A3 (xx)
CA (1)	CA1075235A (xx)
CH (1)	CH606079A5 (xx)
CS (1)	CS203157B2 (xx)
DD (1)	DD131019A5 (xx)
DE (1)	DE2726839C3 (xx)
DK (1)	DK147942C (xx)
EG (1)	EG12742A (xx)
ES (1)	ES459832A1 (xx)
FI (1)	FI771873A (xx)
FR (1)	FR2355029A1 (xx)
GR (1)	GR66411B (xx)
HU (1)	HU179054B (xx)
IE (1)	IE45389B1 (xx)
IL (1)	IL52181A (xx)
LU (1)	LU77557A1 (xx)
MX (1)	MX4323E (xx)
NL (1)	NL170736C (xx)
NO (1)	NO144851C (xx)
NZ (1)	NZ184213A (xx)
PH (1)	PH14663A (xx)
PL (1)	PL108094B1 (xx)
PT (1)	PT66669B (xx)
RO (1)	RO73516A (xx)
SE (1)	SE7706944L (xx)
SU (1)	SU865128A3 (xx)
YU (1)	YU132577A (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK308878A (da) *	1977-08-18	1979-02-19	Pfizer	Aminoglyosidderivater og fremgangsmaader til deres fremstilling
DE2832268A1 (de) *	1978-07-22	1980-01-31	Bayer Ag	Pseudotrisaccharide
DE2928183A1 (de) *	1979-07-12	1981-01-29	Bayer Ag	1-n-alkylsisomicin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JPS5931266A (ja) *	1982-08-11	1984-02-20	株式会社日立製作所	エレベ−タ−の制御装置
KR100450607B1 (ko) *	2002-07-11	2004-09-30	경동제약 주식회사	가라민 유도체의 제조방법
US7794713B2 (en)	2004-04-07	2010-09-14	Lpath, Inc.	Compositions and methods for the treatment and prevention of hyperproliferative diseases
US7862812B2 (en)	2006-05-31	2011-01-04	Lpath, Inc.	Methods for decreasing immune response and treating immune conditions
MX2010005632A (es)	2007-11-21	2010-09-10	Achaogen Inc	Analogos de aminoglucosidos antibacterianos.
CA2761756A1 (en) *	2009-05-14	2010-11-18	Achaogen, Inc.	Treatment of urinary tract infections with antibacterial aminoglycoside compounds
WO2010132760A1 (en)	2009-05-15	2010-11-18	Achaogen, Inc.	Antibacterial derivatives of tobramycin
WO2010132759A1 (en)	2009-05-15	2010-11-18	Achaogen, Inc.	Antibacterial derivatives of dibekacin
WO2010132768A1 (en)	2009-05-15	2010-11-18	Achaogen, Inc.	Antibacterial derivatives of sisomicin
WO2010132757A2 (en)	2009-05-15	2010-11-18	Achaogen, Inc.	Antibacterial aminoglycoside analogs
WO2010132765A2 (en)	2009-05-15	2010-11-18	Achaogen, Inc.	Antibacterial aminoglycoside analogs

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1033394A (en) *	1962-04-03	1966-06-22	Rit Rech Ind Therapeut	New therapeutic agents
US4002742A (en) *	1974-03-19	1977-01-11	Schering Corporation	1-N-alkyl-4,6-di-(aminoglycosyl)-1,3-diaminocyclitols, methods for their manufacture, methods for their use as antibacterial agents, and compositions useful therefor
US4000261A (en) *	1974-11-29	1976-12-28	Schering Corporation	5-epi-4,6-di-o-(aminoglycosyl)-2-deoxystreptamines, methods for their manufacture and intermediates useful therein, methods for their use as antibacterial agents and compositions useful therefor
US4000262A (en) *	1974-11-29	1976-12-28	Schering Corporation	5-epi-amino and 5-epi-azido-4,6-di-o-(aminoglycosyl)-2,5-dideoxystreptamines 1-n-alkyl-5-epi-amino and 1-n-alkyl-5-epi-azido-4,6-di-o-(aminoglycosyl)-2,5-dideoxystreptamines
US4062947A (en) *	1975-11-04	1977-12-13	Schering Corporation	Di-N-alkylaminoglycosides, methods for their manufacture and novel intermediates useful therein, method for their use as antibacterial agents and pharmaceutical compositions useful therefor
US4085208A (en) *	1976-06-21	1978-04-18	Schering Corporation	Process for preparing 4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols and novel 1-epimers and 1-N-alkyl derivatives produced thereby; methods for the use of the 1-epimer derivatives as antibacterial agents and compositions useful therefor

1977
- 1977-05-26 NZ NZ184213A patent/NZ184213A/xx unknown
- 1977-05-27 IL IL52181A patent/IL52181A/xx unknown
- 1977-05-27 YU YU01325/77A patent/YU132577A/xx unknown
- 1977-05-30 EG EG329/77A patent/EG12742A/xx active
- 1977-05-31 PH PH19833A patent/PH14663A/en unknown
- 1977-06-02 MX MX775775U patent/MX4323E/es unknown
- 1977-06-03 AR AR267934A patent/AR222781A1/es active
- 1977-06-03 CA CA279,773A patent/CA1075235A/en not_active Expired
- 1977-06-08 CS CS773790A patent/CS203157B2/cs unknown
- 1977-06-13 BG BG036611A patent/BG28071A3/xx unknown
- 1977-06-13 AT AT414277A patent/AT350722B/de not_active IP Right Cessation
- 1977-06-14 PT PT66669A patent/PT66669B/pt unknown
- 1977-06-14 FI FI771873A patent/FI771873A/fi not_active Application Discontinuation
- 1977-06-14 NL NLAANVRAGE7706514,A patent/NL170736C/xx not_active IP Right Cessation
- 1977-06-14 GR GR53699A patent/GR66411B/el unknown
- 1977-06-14 DE DE2726839A patent/DE2726839C3/de not_active Expired
- 1977-06-14 NO NO772089A patent/NO144851C/no unknown
- 1977-06-15 FR FR7718367A patent/FR2355029A1/fr active Granted
- 1977-06-15 SU SU772494017A patent/SU865128A3/ru active
- 1977-06-15 DK DK265577A patent/DK147942C/da not_active IP Right Cessation
- 1977-06-15 HU HU77PI580A patent/HU179054B/hu unknown
- 1977-06-15 SE SE7706944A patent/SE7706944L/xx not_active Application Discontinuation
- 1977-06-15 RO RO7790693A patent/RO73516A/ro unknown
- 1977-06-15 CH CH737577A patent/CH606079A5/xx not_active IP Right Cessation
- 1977-06-15 PL PL1977198872A patent/PL108094B1/pl not_active IP Right Cessation
- 1977-06-15 JP JP7094477A patent/JPS52153943A/ja active Granted
- 1977-06-15 DD DD7700199503A patent/DD131019A5/xx unknown
- 1977-06-15 IE IE1222/77A patent/IE45389B1/en unknown
- 1977-06-16 LU LU77557A patent/LU77557A1/xx unknown
- 1977-06-16 ES ES459832A patent/ES459832A1/es not_active Expired
1978
- 1978-11-07 US US05/958,409 patent/US4214074A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
AT350722B (de)	1979-06-11
DE2726839C3 (de)	1980-05-14
CS203157B2 (en)	1981-02-27
EG12742A (en)	1979-12-31
IL52181A (en)	1981-03-31
DE2726839A1 (de)	1978-03-09
GR66411B (xx)	1981-03-20
DK147942B (da)	1985-01-14
DD131019A5 (de)	1978-05-24
LU77557A1 (fr)	1979-03-26
SU865128A3 (ru)	1981-09-15
CA1075235A (en)	1980-04-08
IE45389L (en)	1977-12-16
NO772089L (no)	1977-12-19
DK265577A (da)	1977-12-17
YU132577A (en)	1982-06-30
JPS5713556B2 (xx)	1982-03-17
IL52181A0 (en)	1977-07-31
DK147942C (da)	1985-09-02
PL108094B1 (pl)	1980-03-31
US4214074A (en)	1980-07-22
IE45389B1 (en)	1982-08-11
NL7706514A (nl)	1977-12-20
SE7706944L (sv)	1977-12-17
PL198872A1 (pl)	1978-03-13
DE2726839B2 (de)	1979-08-30
JPS52153943A (en)	1977-12-21
RO73516A (ro)	1981-08-30
FR2355029A1 (fr)	1978-01-13
CH606079A5 (xx)	1978-10-13
NO144851C (no)	1981-11-25
MX4323E (es)	1982-03-24
NO144851B (no)	1981-08-17
FI771873A (xx)	1977-12-17
AU2551177A (en)	1978-04-13
ES459832A1 (es)	1978-12-16
PT66669A (en)	1977-07-01
PT66669B (en)	1978-11-13
AR222781A1 (es)	1981-06-30
BG28071A3 (en)	1980-02-25
NZ184213A (en)	1980-05-27
HU179054B (en)	1982-08-28
FR2355029B1 (xx)	1980-04-18
ATA414277A (de)	1978-11-15
NL170736C (nl)	1982-12-16

Publication	Publication Date	Title
JPS5287168A (en)	1977-07-20	Pyrazole derivatives and antibacterial composition
PH19543A (en)	1986-05-20	Cephalosporin derivatives, an antimicrobial composition containing same and method of use thereof
JPS5446754A (en)	1979-04-12	Benzhydrylguanidine derivatives and their use
PH14663A (en)	1981-10-20	1-n-hydroxyalkyl derivatives of aminoclycoside antibiotics and their use as antibacterial agents
GB1533375A (en)	1978-11-22	Halogenated 1-azolyl-butane derivatives and their use as fungicides
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JPS5287170A (en)	1977-07-20	Novel acylated triazolyll o*nnacetal and use of same as pasteurizing agent
MY8500128A (en)	1985-12-31	New cephalosporin derivatives, their production and use as antimicrobial agents
GB2005256B (en)	1982-02-03	Antibiotic its preparation and use
JPS55129267A (en)	1980-10-06	33substituted pyridine derivative* its manufacture and use as antibacterial
IL52289A0 (en)	1977-08-31	Beta-lactam antibiotics and preparation thereof
JPS5295667A (en)	1977-08-11	Production of acylated imidazolyllo*nnacetal and use of same as antibacterial agent
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JPS5318527A (en)	1978-02-20	Bissphenol derivatives composition and its use
ZA774331B (en)	1978-06-28	Novel halogenated 1-azolyl-butane derivatives and their use as fungicides
JPS5435219A (en)	1979-03-15	Antibacterial agent and use
JPS55100392A (en)	1980-07-31	Novel cephalosporin derivative* its manufacture and use
JPS55129251A (en)	1980-10-06	Substituted nnaryllacetoanilide*its manufacture and use as antibacterial
JPS5683479A (en)	1981-07-08	Novel oxybenztriazole derivatives* their manufacture and their use
IL45672A0 (en)	1974-11-29	Anti-microbial agents containing 1-ethyltriazole derivatives and their use
GB1538764A (en)	1979-01-24	Tetraaza-sulpha-heptenone derivatives and their use as pesticides
GB1516938A (en)	1978-07-05	Halopyridylamides of m-aminotetramisole and their use as anthelmintics
PH16300A (en)	1983-09-05	Notrothiazoline derivatives and their use as schistosonicidal agents
JPS52113964A (en)	1977-09-24	33imidazolylpyrazol derivatives and use of same