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PE71699A1 - Composicion farmaceutica de descarboetoxiloratadina sin lactosa, no higroscopica y anhidra - Google Patents

Composicion farmaceutica de descarboetoxiloratadina sin lactosa, no higroscopica y anhidra

Info

Publication number
PE71699A1
PE71699A1 PE1998000074A PE00007498A PE71699A1 PE 71699 A1 PE71699 A1 PE 71699A1 PE 1998000074 A PE1998000074 A PE 1998000074A PE 00007498 A PE00007498 A PE 00007498A PE 71699 A1 PE71699 A1 PE 71699A1
Authority
PE
Peru
Prior art keywords
hygroscopic
free
lactose
pharmaceutical composition
tablet
Prior art date
Application number
PE1998000074A
Other languages
English (en)
Inventor
Martin P Redmon
Hal T Butler
Stephen A Wald
Paul D Rubin
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27365195&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE71699(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sepracor Inc filed Critical Sepracor Inc
Publication of PE71699A1 publication Critical patent/PE71699A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/618—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate
    • A61K31/621—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate having the hydroxy group in position 2 esterified, e.g. benorylate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Transplantation (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

CARACTERIZADA POR PRESENTARSE EN FORMA DE MEZCLA O GRANULADO, BASICAMENTE LIBRE DE EXCIPIENTES REACTIVOS TAL COMO LACTOSA; LA CANTIDAD EFECTIVA A NIVEL TERAPEUTICO ES ENTRE 0,1 mg. Y 10 mg.; PUEDE CONTENER ADEMAS UN ANALGESICO QUE SE SELECCIONA DE ACIDO ACETILSALICILICO, ACETAMINOFENO, IBUPROFENO, ENTRE OTROS; ADEMAS PUEDE CONTENER UN DESCONGESTIONANTE. SE PRESENTA EN FORMA DE COMPRIMIDO, CAPSULA O TABLETA. TAMBIEN SE REFIERE A UN COMPOSICION FARMACEUTICA a)ANHIDRA; b)DONDE LA DESCARBOETOXILORATADINA ESTA LIBRE DE AGUA NO COMBINADA EN EL QUE EL O LOS EXCIPIENTES INERTES SON NO HIGROSCOPICOS Y DE ESCASA HUMEDAD, c)SOLIDA Y NO HIGROSCOPICA, d)NO RECUBIERTA, LIBRE DE EXCIPIENTES REACTIVOS. TAMBIEN SE REFIERE A LA PRESENTACION DEL COMPUESTO EN FORMA DE GRANULADO CUBIERTO CON UN AGENTE DE RECUBRIMIENTO INERTE, QUE CONSISTE EN UN AGENTE GENERADOR DE PELICULAS QUE SE SELECCIONA DE METILCELULOSA, CELULOSA HIDROXIMETALICA, CARBOXIMETILCELULOSA, ENTRE OTROS; TAMBIEN SE PRESENTA EN FORMA SOLIDA DE LIBERACION INSTANTANEA QUE CONTIENE UNA RED DE MATRIZ ABIERTA SIENDO SOLUBLE EN AGUA
PE1998000074A 1997-02-07 1998-02-03 Composicion farmaceutica de descarboetoxiloratadina sin lactosa, no higroscopica y anhidra PE71699A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3732597P 1997-02-07 1997-02-07
US4518497P 1997-04-30 1997-04-30
US5305097P 1997-07-21 1997-07-21

Publications (1)

Publication Number Publication Date
PE71699A1 true PE71699A1 (es) 1999-08-03

Family

ID=27365195

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1998000074A PE71699A1 (es) 1997-02-07 1998-02-03 Composicion farmaceutica de descarboetoxiloratadina sin lactosa, no higroscopica y anhidra

Country Status (29)

Country Link
US (2) US20020123504A1 (es)
EP (2) EP0969836B1 (es)
JP (1) JP2001511184A (es)
KR (5) KR20080003012A (es)
CN (1) CN1132579C (es)
AR (3) AR011114A1 (es)
AT (1) ATE345133T1 (es)
AU (1) AU6271998A (es)
BR (1) BR9806157A (es)
CA (1) CA2267136C (es)
CO (1) CO4940445A1 (es)
CZ (1) CZ119499A3 (es)
DE (1) DE69836424T2 (es)
DK (1) DK0969836T3 (es)
ES (1) ES2271986T3 (es)
HK (1) HK1024187A1 (es)
HU (1) HUP0001527A3 (es)
MY (1) MY136999A (es)
NO (2) NO325611B1 (es)
NZ (1) NZ335041A (es)
PE (1) PE71699A1 (es)
PL (1) PL192075B1 (es)
PT (1) PT969836E (es)
RU (1) RU2209627C2 (es)
SK (1) SK286035B6 (es)
TW (1) TW522014B (es)
UA (1) UA70290C2 (es)
WO (1) WO1998034614A1 (es)
ZA (1) ZA98977B (es)

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ECSP077628A (es) 2007-05-03 2008-12-30 Smithkline Beechman Corp Nueva composición farmacéutica
TR200806298A2 (tr) 2008-08-22 2010-03-22 Bi̇lgi̇ç Mahmut Farmasötik formülasyon
WO2010094471A1 (en) 2009-02-17 2010-08-26 Krka, D. D., Novo Mesto Pharmaceutical compositions comprising prasugrel base or its pharmaceutically acceptable acid addition salts and processes for their preparation
ATE525064T1 (de) 2009-07-01 2011-10-15 Tiefenbacher Alfred E Gmbh & Co Kg Pharmazeutische zusammensetzung mit desloratadin
WO2011141483A2 (en) 2010-05-10 2011-11-17 Laboratorios Lesvi, S.L. Stable pharmaceutical formulations containing an antihistaminic
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CN102813640B (zh) * 2012-09-06 2016-12-21 无锡万全医药技术有限公司 一种含地氯雷他定的软胶囊及其制备方法
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Also Published As

Publication number Publication date
PL334232A1 (en) 2000-02-14
DE69836424T2 (de) 2007-09-27
HUP0001527A2 (hu) 2001-04-28
EP1614421A2 (en) 2006-01-11
RU2209627C2 (ru) 2003-08-10
CZ119499A3 (cs) 1999-08-11
EP0969836B1 (en) 2006-11-15
KR20060076330A (ko) 2006-07-04
ATE345133T1 (de) 2006-12-15
PL192075B1 (pl) 2006-08-31
SK47299A3 (en) 2000-03-13
CN1246794A (zh) 2000-03-08
CA2267136C (en) 2000-11-28
NO325611B1 (no) 2008-06-23
KR20000068914A (ko) 2000-11-25
EP0969836A1 (en) 2000-01-12
HUP0001527A3 (en) 2002-01-28
JP2001511184A (ja) 2001-08-07
DK0969836T3 (da) 2007-03-19
CO4940445A1 (es) 2000-07-24
NO992157L (no) 1999-05-04
AR064896A2 (es) 2009-05-06
KR20060132053A (ko) 2006-12-20
NO20075846L (no) 1999-05-04
MY136999A (en) 2008-12-31
ZA98977B (en) 1998-07-30
US20060079489A1 (en) 2006-04-13
ES2271986T3 (es) 2007-04-16
PT969836E (pt) 2007-01-31
AR064895A2 (es) 2009-05-06
KR20080003012A (ko) 2008-01-04
TW522014B (en) 2003-03-01
NZ335041A (en) 2000-09-29
NO992157D0 (no) 1999-05-04
EP1614421A3 (en) 2006-02-15
UA70290C2 (uk) 2004-10-15
AR011114A1 (es) 2000-08-02
US20020123504A1 (en) 2002-09-05
CN1132579C (zh) 2003-12-31
KR100624259B1 (ko) 2006-09-13
AU6271998A (en) 1998-08-26
WO1998034614A1 (en) 1998-08-13
HK1024187A1 (en) 2000-10-05
BR9806157A (pt) 2001-01-09
SK286035B6 (sk) 2008-01-07
KR20070086880A (ko) 2007-08-27
DE69836424D1 (de) 2006-12-28

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