PE20141175A1 - FORMULACION PARA ANTICUERPO ANTI-alfa4�7 - Google Patents

FORMULACION PARA ANTICUERPO ANTI-alfa4�7

Info

Publication number: PE20141175A1
Authority: PE; Peru
Prior art keywords: formulation; antibody; alpha4; moles; amino acid
Prior art date: 2011-05-02

Application number

PE2013002431A

Other languages

English (en)

Spanish (es)

Inventor

Willow Diluzio

Nobel T Truong

Csanad M Varga

Vaithianathan Palaniappan

Jason Brown

Irving H Fox

Catherine Scholz

Original Assignee

Millennium Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-05-02

Filing date

2012-05-02

Publication date

2014-09-25

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46085207&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20141175(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2012-05-02 Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc

2014-09-25 Publication of PE20141175A1 publication Critical patent/PE20141175A1/es

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Oil, Petroleum & Natural Gas (AREA)
Microbiology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Mycology (AREA)
Dermatology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Medicinal Preparation (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PE2013002431A 2011-05-02 2012-05-02 FORMULACION PARA ANTICUERPO ANTI-alfa4�7 PE20141175A1 (es)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date
US201161481533P	2011-05-02	2011-05-02
US201161550545P	2011-10-24	2011-10-24
US201261585859P	2012-01-12	2012-01-12

Publications (1)

Publication Number	Publication Date
PE20141175A1 true PE20141175A1 (es)	2014-09-25

Family

ID=46085207

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PE2013002431A PE20141175A1 (es)	2011-05-02	2012-05-02	FORMULACION PARA ANTICUERPO ANTI-alfa4�7
PE2018001579A PE20190405A1 (es)	2011-05-02	2012-05-02	FORMULACION PARA ANTICUERPO ANTI-alfa4beta7

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PE2018001579A PE20190405A1 (es)	2011-05-02	2012-05-02	FORMULACION PARA ANTICUERPO ANTI-alfa4beta7

Country Status (41)

Country	Link
US (14)	US20120282249A1 (zh)
EP (4)	EP3329965B1 (zh)
JP (7)	JP6190360B2 (zh)
KR (7)	KR101923371B1 (zh)
CN (4)	CN108129565B (zh)
AR (1)	AR086237A1 (zh)
AU (6)	AU2012250873B2 (zh)
BR (1)	BR112013028424A2 (zh)
CA (2)	CA2834867C (zh)
CL (2)	CL2013003146A1 (zh)
CO (1)	CO6801647A2 (zh)
CR (1)	CR20130677A (zh)
CY (1)	CY1119435T1 (zh)
DK (1)	DK2704798T3 (zh)
DO (1)	DOP2013000253A (zh)
EA (1)	EA032729B1 (zh)
EC (2)	ECSP13013050A (zh)
ES (1)	ES2645187T3 (zh)
GE (1)	GEP201706734B (zh)
HK (2)	HK1249466A1 (zh)
HR (1)	HRP20171432T1 (zh)
HU (1)	HUE036663T2 (zh)
IL (5)	IL296838A (zh)
LT (1)	LT2704798T (zh)
MA (1)	MA35136B1 (zh)
ME (1)	ME02859B (zh)
MX (3)	MX348814B (zh)
MY (2)	MY183471A (zh)
PE (2)	PE20141175A1 (zh)
PH (3)	PH12013502236A1 (zh)
PL (1)	PL2704798T3 (zh)
PT (1)	PT2704798T (zh)
RS (1)	RS56397B1 (zh)
SG (1)	SG194652A1 (zh)
SI (1)	SI2704798T1 (zh)
SM (1)	SMT201700508T1 (zh)
TW (3)	TWI556828B (zh)
UA (2)	UA116189C2 (zh)
UY (1)	UY34053A (zh)
WO (1)	WO2012151248A2 (zh)
ZA (3)	ZA201308069B (zh)

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KR20180050435A (ko)	2018-05-14
US20180289811A1 (en)	2018-10-11
JP2019108400A (ja)	2019-07-04
BR112013028424A2 (pt)	2021-05-04
JP2023076616A (ja)	2023-06-01
AU2012250873B2 (en)	2016-07-07
CN103608071B (zh)	2017-12-26
EP3329965B1 (en)	2025-03-19
IL267668B (en)	2020-10-29
US20190076532A1 (en)	2019-03-14
CA3028209A1 (en)	2012-11-08
AU2012250873A1 (en)	2013-05-09
US9663579B2 (en)	2017-05-30
AU2020250249B2 (en)	2022-10-06
JP6878489B2 (ja)	2021-05-26
UA126545C2 (uk)	2022-11-02
KR20140145953A (ko)	2014-12-24
AU2018278866A1 (en)	2019-01-03
EP4378484A2 (en)	2024-06-05
JP7258941B2 (ja)	2023-04-17
UY34053A (es)	2012-11-30
AU2016231469B2 (en)	2018-12-20
IL267668A (en)	2019-08-29
KR20180127540A (ko)	2018-11-28
DOP2013000253A (es)	2013-12-31
TW201906631A (zh)	2019-02-16
PH12013502236A1 (en)	2014-01-06
CN108079291A (zh)	2018-05-29
IL296847A (en)	2022-11-01
US20140377251A1 (en)	2014-12-25
IL296838A (en)	2022-11-01
ECSP13013050A (es)	2014-01-31
AU2018278866B2 (en)	2020-07-09
PH12020500336A1 (en)	2021-02-22
UA116189C2 (uk)	2018-02-26
MA35136B1 (fr)	2014-05-02
MX2021006723A (es)	2022-05-03
ES2645187T3 (es)	2017-12-04
CR20130677A (es)	2014-10-07
AR086237A1 (es)	2013-11-27
AU2022231726A1 (en)	2022-10-06
EP4378484A3 (en)	2024-09-04
ZA201308069B (en)	2016-01-27
US20120282249A1 (en)	2012-11-08
CO6801647A2 (es)	2013-11-29
TW201247223A (en)	2012-12-01
US20220370617A1 (en)	2022-11-24
KR102096484B1 (ko)	2020-04-02
IL229104A0 (en)	2013-12-31
US20170002078A1 (en)	2017-01-05
CA2834867A1 (en)	2012-11-08
CY1119435T1 (el)	2018-03-07
HRP20171432T1 (hr)	2017-11-03
KR101923371B1 (ko)	2018-11-29
CA3028209C (en)	2021-01-05
GEP201706734B (en)	2017-09-25
SMT201700508T1 (it)	2017-11-15
CL2017000830A1 (es)	2017-12-22
US20200206353A1 (en)	2020-07-02
SI2704798T1 (sl)	2017-12-29
CN108129565B (zh)	2022-09-20
PH12018500030B1 (en)	2022-05-04
EP3329965A1 (en)	2018-06-06
US20250041424A1 (en)	2025-02-06
MY172735A (en)	2019-12-11
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