[go: up one dir, main page]

PE20041026A1 - Composicion que comprende un inhibidor de ciclooxigenasa-2 selectivo soluble en agua - Google Patents

Composicion que comprende un inhibidor de ciclooxigenasa-2 selectivo soluble en agua

Info

Publication number
PE20041026A1
PE20041026A1 PE2003001182A PE2003001182A PE20041026A1 PE 20041026 A1 PE20041026 A1 PE 20041026A1 PE 2003001182 A PE2003001182 A PE 2003001182A PE 2003001182 A PE2003001182 A PE 2003001182A PE 20041026 A1 PE20041026 A1 PE 20041026A1
Authority
PE
Peru
Prior art keywords
skin
water
inhibitor
composition including
drugs
Prior art date
Application number
PE2003001182A
Other languages
English (en)
Inventor
Kathryn M Kienle
Gary D Ewing
Brenda M Stoller
Lu Guang Wei
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of PE20041026A1 publication Critical patent/PE20041026A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

PARA SER APLICADO A UN AREA DE LA PIEL EN EL TRATAMIENTO LOCAL Y/O SISTEMICO DE UN TRANSTORNO MEDIADO POR COX-2, Y QUE COMPRENDE: 1)UNA LAMINA DE SOPORTE QUE PUEDE CONFORMARSE DE FORMA FLEXIBLE AL AREA DE LA PIEL, TENIENDO LA MISMA SUPERFICIES ENFRENTADAS QUE ESTAN RESPECTIVAMENTE DISTAL Y PROXIMAL A LA PIEL CUANDO SE APLICA; Y, 2)UN RECUBRIMIENTO SOBRE LA SUPERFICIE PROXIMAL DE (1), QUE A SU VEZ COMPRENDE: a)UN ADHESIVO; b)UN AGENTE ACTIVO SOLUBLE EN AGUA SELECCIONADO DE: FARMACOS O PROFARMACOS, O SUS SALES INHIBIDORES DE COX-2 SELECTIVOS, EL CUAL ESTA EN UNA CANTIDAD TOTAL TERAPEUTICAMENTE EFECTIVA Y DISPERSO EN UNA MATRIZ QUE COMPRENDE DE CERO A MENOS DE UNA CANTIDAD EFECTIVA PARA SOLUBILIZAR EL AGENTE ACTIVO EN TOTAL DE UNO O MAS DISOLVENTES DISTINTOS DEL ADHESIVO
PE2003001182A 2002-11-21 2003-11-21 Composicion que comprende un inhibidor de ciclooxigenasa-2 selectivo soluble en agua PE20041026A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42820102P 2002-11-21 2002-11-21

Publications (1)

Publication Number Publication Date
PE20041026A1 true PE20041026A1 (es) 2005-02-05

Family

ID=32393362

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2003001182A PE20041026A1 (es) 2002-11-21 2003-11-21 Composicion que comprende un inhibidor de ciclooxigenasa-2 selectivo soluble en agua

Country Status (15)

Country Link
US (1) US20040126415A1 (es)
EP (1) EP1572166A1 (es)
JP (1) JP2006509759A (es)
AR (1) AR042102A1 (es)
AU (1) AU2003291386A1 (es)
BR (1) BR0316463A (es)
CA (1) CA2506628A1 (es)
GT (1) GT200300249A (es)
MX (1) MXPA05004989A (es)
NL (1) NL1024830C2 (es)
PA (1) PA8589001A1 (es)
PE (1) PE20041026A1 (es)
TW (1) TW200503787A (es)
UY (1) UY28086A1 (es)
WO (1) WO2004047814A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA012599B1 (ru) 2003-04-10 2009-10-30 Ньюроджескс, Инк. Способы и композиции для введения агонистов trpv1
US7666914B2 (en) * 2004-06-03 2010-02-23 Richlin David M Topical preparation and method for transdermal delivery and localization of therapeutic agents
ZA200707492B (en) * 2005-02-14 2009-02-25 Neurogesx Inc Device for delivery of TRPV1 agonists
CA2602832A1 (en) * 2005-03-30 2006-10-05 Keith R. Bley Low-concentration capsaicin patch and methods for treating neuropathic pain
DE102005050431A1 (de) * 2005-10-21 2007-04-26 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System zur Verabreicherung lipophiler und/oder wenig hautpermeabler Wirkstoffe
US20090081281A1 (en) * 2006-05-10 2009-03-26 Gerard Farmer Photosensitizer Formulation for Topical Applications
DE102006054732B4 (de) * 2006-11-21 2010-12-30 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit Ionenpaar-Mikroreservoiren
JP4327841B2 (ja) * 2006-12-20 2009-09-09 日東電工株式会社 経皮吸収製剤の製造装置および製造方法
WO2009143070A1 (en) * 2008-05-21 2009-11-26 Teikoku Pharma Usa, Inc. Treatment of dysmenorrhea via transdermal administration of nonsteroidal anti-inflammatory drugs
JP2012020991A (ja) * 2010-06-16 2012-02-02 Takasago Internatl Corp 経皮吸収促進剤、及びこれを含有する皮膚外用製剤
US9814911B2 (en) * 2011-07-15 2017-11-14 Robert Benson Aylor Skin and hair treatments
CA2966843A1 (en) * 2014-11-10 2016-05-19 Achelios Therapeutics, Inc. Sprayable analgesic compositions
KR102042456B1 (ko) * 2018-03-22 2019-11-08 크리스탈지노믹스(주) 경피흡수제제

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE03685B1 (et) * 1996-04-12 2002-04-15 G.D. Searle & Co. Asendatud benseensulfoonamiidi derivaadid kui COX-2 inhibiitorite eelravimid
US5952000A (en) * 1996-10-30 1999-09-14 Theratech, Inc. Fatty acid esters of lactic acid salts as permeation enhancers
ES2197077T3 (es) * 1999-03-01 2004-01-01 Amarin Technologies S.A. Dispositivo transdermico que comprende farmacos anti-inflamatorios no esteroides incorporados en una matriz de un polimero acrilico adhesivo.
US6309663B1 (en) * 1999-08-17 2001-10-30 Lipocine Inc. Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents
IN191512B (es) * 2000-01-21 2003-12-06 Panacea Biotech
DE10032132A1 (de) * 2000-07-01 2002-01-17 Lohmann Therapie Syst Lts Dermales Therapeutisches System enthaltend nichtsteroidale Antiphlogistika mit selektiver COX-2-Hemmung
AU2002306868A1 (en) * 2001-03-28 2002-10-15 Pharmacia Corporation Therapeutic combinations for cardiovascular and inflammatory indications
HUP0600294A2 (en) * 2001-05-31 2007-02-28 Pharmacia Corp Skin-permeable selective cyclooxygenase-2 inhibitor composition
JP4283507B2 (ja) * 2002-08-02 2009-06-24 久光製薬株式会社 経皮投与用貼付剤

Also Published As

Publication number Publication date
AU2003291386A1 (en) 2004-06-18
MXPA05004989A (es) 2005-08-02
US20040126415A1 (en) 2004-07-01
CA2506628A1 (en) 2004-06-10
EP1572166A1 (en) 2005-09-14
WO2004047814A1 (en) 2004-06-10
GT200300249A (es) 2004-07-12
NL1024830A1 (nl) 2004-05-26
BR0316463A (pt) 2005-10-11
AR042102A1 (es) 2005-06-08
NL1024830C2 (nl) 2006-03-06
UY28086A1 (es) 2004-06-30
TW200503787A (en) 2005-02-01
JP2006509759A (ja) 2006-03-23
PA8589001A1 (es) 2005-02-04

Similar Documents

Publication Publication Date Title
PE20041026A1 (es) Composicion que comprende un inhibidor de ciclooxigenasa-2 selectivo soluble en agua
BR0312268A (pt) Dispositivos transdermais para liberação de droga que têm microprotrusões revestidas
BRPI0417437A (pt) dispositivo para inibição da absorção, dispositivo para remoção de agente fisiologicamente ativo e dispositivo para redução do efeito de overdose
MXPA04001491A (es) Dispositivo de liberacion de farmaco erosionable mucoadhesivo para la administracion controlada de compuestos activos farmaceuticos y otros compuestos activos.
BRPI0415986A (pt) método e aparelho para reduzir a incidência do uso de tabaco
WO2004078122A3 (en) Invisible patch for active agnet controlled delivery
AR042104A1 (es) Lamina revestida de adhesivo para administracion dermica de un inhibidor selectivo de ciclooxigenasa -2
BRPI0313148B8 (pt) formulações sólidas matriciais de lamotrigina contendo revestimento externo e perfuração em tal revestimento
BRPI0514031A (pt) artigos absorventes compreendendo um agente modificador de exsudado corpóreo e uma formulação de cuidado com a pele que forma filme
WO2006083681A3 (en) Coated microprojections having reduced variability and method for producing same
DK1333880T3 (da) Indretninger med coatede mikrofremspring til medikamentafgivelse gennem huden
BR0012046A (pt) Composto heterocìclico, composição farmacêutica, inibidor de ativação de ap-1 ou um inibidor da ativação de nf-kappab, inibidor da produção de citocina inflamatória, e, inibidor da produção de metaloprotease de matriz ou inibidor da expressão do fator de adesão de célula inflamatória
ATE319488T1 (de) Bioaktive-wirkstofffreisetzende beschichtung mit aromatischen poly(meth)acrylaten
BR0008254A (pt) Combinações para o tratamento de doenças que envolvam angiogênese
WO2011029948A3 (de) Transdermales therapeutisches system zur verabreichung von fentanyl oder einem analogstoff davon
BR0208005A (pt) Preparação para adesivo tópico contendo indutor de hipersensibilidade do tipo retardado e processos para a utilização do mesmo
NO20062234L (no) Transdemisk,farmasoytisk spray-formulering omfattende en VP/UA kopolymer og en ikke-vandig vehikkel
DE50109226D1 (de) Dermales therapeutisches system enthaltend nichtsteroidale antiphlogistika mit selektiver cox-2-hemmung
AR021459A1 (es) PARCHE QUE CONTIENE ESTRADIOL PARA LA APLICACIoN PERCUTÁNEA DE HORMONAS.
MXPA05010384A (es) Composiciones adherentes para el cuidado de la piel y articulos que tienen las composiciones adherentes para el cuidado de la piel colocadas encima.
MX2009008993A (es) Dispositivo para la administracion percutanea de bisoprolol.
DK1046395T3 (da) Plaster indeholdende heparin og diclofenac til topisk anvendelse
ES2188995T3 (es) Uso de un inhibidor de la h+, k+-atpasa en el tratamiento de los polipos nasales.
BRPI0406858A (pt) Liberação controlada de agentes altamente solúveis
BR0316436A (pt) Emplastro inibidor seletivo de ciclooxigenase-2

Legal Events

Date Code Title Description
FC Refusal