PE20020487A1 - Terapia antitumoral comprendiendo la administracion de derivados de la distamicina - Google Patents
Terapia antitumoral comprendiendo la administracion de derivados de la distamicinaInfo
- Publication number
- PE20020487A1 PE20020487A1 PE2001000967A PE2001000967A PE20020487A1 PE 20020487 A1 PE20020487 A1 PE 20020487A1 PE 2001000967 A PE2001000967 A PE 2001000967A PE 2001000967 A PE2001000967 A PE 2001000967A PE 20020487 A1 PE20020487 A1 PE 20020487A1
- Authority
- PE
- Peru
- Prior art keywords
- cancer
- administration
- cicaplotino
- week
- refers
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
SE REFIERE AL USO DE UN DERIVADO DE O-HALOGENO-ACRILOIL DISTAMICINA DE FORMULA I DONDE R ES Br, Cl, PARA LA PREAPARACION DE UN MEDICAMENTO PARA EL TRATAMIENTO DE TUMORES GASTROINTESTINALES, CANCER COLORECTAL, CANCER GASTROESOFAGICO, CANCER DE HIGADO, QUE COMPRENDE LA INFUSION ENDOVENOSA POR 3-4 SEMANAS DE 0,85mg/m2 A 20mg/m2 DE AREA DE SUPERFICIECORPORAL O SEMANALMENTE POR 3 SEMANAS CONSECUTIVAS DE 0,3mg/m2/SEMANA A 7mg/m2/SEMANA; TAMBIEN SE REFIERE AL USO CON MELFALAN, CLORAMBUCIL, MECLORETAMINA, CICLOFOSFAMIDA, IFOSFAMIDA, BUSULFAN, CARMUSTINA, LORMUSTINA, SEMUSTINA, FOTEMUSTINA, DACARBAZIDA, TEMOZOLOMIDA, TIOPEDA, MITOMICINA C, CISPLATINO, CARBOPLATINO, OXALIPLATINO, NEDAPLATINO, CAMPTOTECINA, ENTRE OTROS
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/676,770 US6576612B1 (en) | 2000-10-02 | 2000-10-02 | Antitumor therapy comprising distamycin derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20020487A1 true PE20020487A1 (es) | 2002-05-23 |
Family
ID=24715919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2001000967A PE20020487A1 (es) | 2000-10-02 | 2001-09-28 | Terapia antitumoral comprendiendo la administracion de derivados de la distamicina |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US6576612B1 (es) |
| EP (1) | EP1345604B1 (es) |
| JP (1) | JP2004510734A (es) |
| KR (1) | KR100827560B1 (es) |
| CN (1) | CN1468099A (es) |
| AT (1) | ATE339202T1 (es) |
| AU (2) | AU2002221622B2 (es) |
| BR (1) | BR0114389A (es) |
| CA (1) | CA2424116A1 (es) |
| CZ (1) | CZ299686B6 (es) |
| DE (1) | DE60123117T2 (es) |
| EA (1) | EA006295B1 (es) |
| EE (1) | EE05241B1 (es) |
| ES (1) | ES2267841T3 (es) |
| HU (1) | HUP0301247A2 (es) |
| IL (1) | IL154755A0 (es) |
| MX (1) | MXPA03002824A (es) |
| MY (1) | MY134690A (es) |
| NO (1) | NO20031410D0 (es) |
| PE (1) | PE20020487A1 (es) |
| PL (1) | PL363926A1 (es) |
| SK (1) | SK5032003A3 (es) |
| WO (1) | WO2002028389A1 (es) |
| ZA (1) | ZA200303405B (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0015446D0 (en) * | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl distamycin derivates,taxanes and/or antimetabolites |
| GB0015447D0 (en) * | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents |
| US6576612B1 (en) * | 2000-10-02 | 2003-06-10 | Pharmacia Italia S.P.A. | Antitumor therapy comprising distamycin derivatives |
| US20070249651A1 (en) * | 2001-06-20 | 2007-10-25 | Nerviano Medical Sciences S.R.I. | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors |
| US6969592B2 (en) * | 2001-09-26 | 2005-11-29 | Pharmacia Italia S.P.A. | Method for predicting the sensitivity to chemotherapy |
| NZ535700A (en) * | 2002-04-02 | 2007-06-29 | Nerviano Medical Sciences Srl | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and radiotherapy |
| WO2004035045A1 (en) * | 2002-10-16 | 2004-04-29 | Pharmacia Italia S.P.A. | Use of substituted acrylolyl distamycin derivatives in combination with demethylating agents, in the treatment of cancer |
| MX2008008470A (es) * | 2005-12-27 | 2008-09-26 | Univ Pais Vasco | Nuevos derivados pirrolicos con actividad inhibidora de desacetilasa de histonas. |
| MD23Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului lobular in situ neinvaziv al glandei mamare |
| MD36Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului ductal in situ neinvaziv al glandei mamare |
| MD35Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de apreciere a riscului dezvoltării carcinomului neinvaziv in situ al glandei mamare |
| MD24Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului neinvaziv al glandei mamare |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8906709D0 (en) * | 1989-03-23 | 1989-05-10 | Creighton Andrew M | Acryloyl substituted pyrrole derivatives |
| GB9615692D0 (en) * | 1996-07-25 | 1996-09-04 | Pharmacia Spa | Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
| GB9806689D0 (en) * | 1998-03-27 | 1998-05-27 | Pharmacia & Upjohn Spa | Acryloyl derivatives analogous to distamycin,process for preparing them,and their use as antitumour and antiviral agents |
| GB9928703D0 (en) | 1999-12-03 | 2000-02-02 | Pharmacia & Upjohn Spa | Acryloyl peptidic derivatives,process for their preparation and their use as antitumour agents |
| US6576612B1 (en) * | 2000-10-02 | 2003-06-10 | Pharmacia Italia S.P.A. | Antitumor therapy comprising distamycin derivatives |
-
2000
- 2000-10-02 US US09/676,770 patent/US6576612B1/en not_active Expired - Lifetime
-
2001
- 2001-09-21 AU AU2002221622A patent/AU2002221622B2/en not_active Ceased
- 2001-09-21 US US10/381,272 patent/US7399748B2/en not_active Expired - Fee Related
- 2001-09-21 MX MXPA03002824A patent/MXPA03002824A/es unknown
- 2001-09-21 BR BR0114389-1A patent/BR0114389A/pt not_active Application Discontinuation
- 2001-09-21 IL IL15475501A patent/IL154755A0/xx not_active IP Right Cessation
- 2001-09-21 EA EA200300427A patent/EA006295B1/ru not_active IP Right Cessation
- 2001-09-21 WO PCT/EP2001/010988 patent/WO2002028389A1/en active IP Right Grant
- 2001-09-21 ES ES01986259T patent/ES2267841T3/es not_active Expired - Lifetime
- 2001-09-21 KR KR1020037004710A patent/KR100827560B1/ko not_active Expired - Fee Related
- 2001-09-21 DE DE60123117T patent/DE60123117T2/de not_active Expired - Lifetime
- 2001-09-21 HU HU0301247A patent/HUP0301247A2/hu unknown
- 2001-09-21 AT AT01986259T patent/ATE339202T1/de active
- 2001-09-21 JP JP2002532214A patent/JP2004510734A/ja not_active Withdrawn
- 2001-09-21 CA CA002424116A patent/CA2424116A1/en not_active Abandoned
- 2001-09-21 SK SK503-2003A patent/SK5032003A3/sk unknown
- 2001-09-21 EP EP01986259A patent/EP1345604B1/en not_active Expired - Lifetime
- 2001-09-21 EE EEP200300129A patent/EE05241B1/xx not_active IP Right Cessation
- 2001-09-21 PL PL01363926A patent/PL363926A1/xx not_active Application Discontinuation
- 2001-09-21 CN CNA018167551A patent/CN1468099A/zh active Pending
- 2001-09-21 CZ CZ20030909A patent/CZ299686B6/cs not_active IP Right Cessation
- 2001-09-21 AU AU2162202A patent/AU2162202A/xx active Pending
- 2001-09-28 MY MYPI20014542A patent/MY134690A/en unknown
- 2001-09-28 PE PE2001000967A patent/PE20020487A1/es not_active Application Discontinuation
-
2003
- 2003-03-27 NO NO20031410A patent/NO20031410D0/no not_active Application Discontinuation
- 2003-05-02 ZA ZA200303405A patent/ZA200303405B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1345604B1 (en) | 2006-09-13 |
| EE05241B1 (et) | 2009-12-15 |
| CA2424116A1 (en) | 2002-04-11 |
| BR0114389A (pt) | 2004-02-03 |
| NO20031410L (no) | 2003-03-27 |
| MXPA03002824A (es) | 2003-07-14 |
| WO2002028389A1 (en) | 2002-04-11 |
| SK5032003A3 (en) | 2003-08-05 |
| ZA200303405B (en) | 2004-05-03 |
| JP2004510734A (ja) | 2004-04-08 |
| ATE339202T1 (de) | 2006-10-15 |
| ES2267841T3 (es) | 2007-03-16 |
| US6576612B1 (en) | 2003-06-10 |
| EA200300427A1 (ru) | 2003-10-30 |
| KR20030096222A (ko) | 2003-12-24 |
| DE60123117T2 (de) | 2007-02-08 |
| MY134690A (en) | 2007-12-31 |
| AU2162202A (en) | 2002-04-15 |
| CZ2003909A3 (cs) | 2003-08-13 |
| DE60123117D1 (de) | 2006-10-26 |
| PL363926A1 (en) | 2004-11-29 |
| HUP0301247A2 (hu) | 2003-09-29 |
| AU2002221622B2 (en) | 2007-05-17 |
| EE200300129A (et) | 2003-06-16 |
| US20040006023A1 (en) | 2004-01-08 |
| KR100827560B1 (ko) | 2008-05-07 |
| CZ299686B6 (cs) | 2008-10-22 |
| US7399748B2 (en) | 2008-07-15 |
| NO20031410D0 (no) | 2003-03-27 |
| CN1468099A (zh) | 2004-01-14 |
| EP1345604A1 (en) | 2003-09-24 |
| EA006295B1 (ru) | 2005-10-27 |
| IL154755A0 (en) | 2003-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |