NZ262664A - Heterocyclic substituted derivatives, and medicaments thereof - Google Patents

Heterocyclic substituted derivatives, and medicaments thereof

Info

Publication number: NZ262664A
Authority: NZ; New Zealand
Prior art keywords: pct; alkyl; mmol; compound; substituted
Prior art date: 1993-02-22

Application number

NZ262664A

Other languages

English (en)

Inventor

David A Claremon

John J Baldwin

Nigel Liverton

Ben Askew

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-02-22

Filing date

1994-02-22

Publication date

1997-04-24

1994-02-22 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1997-04-24 Publication of NZ262664A publication Critical patent/NZ262664A/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- A61K38/166—Streptokinase
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Hematology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Peptides Or Proteins (AREA)

NZ262664A 1993-02-22 1994-02-22 Heterocyclic substituted derivatives, and medicaments thereof NZ262664A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US2051793A	1993-02-22	1993-02-22

Publications (1)

Publication Number	Publication Date
NZ262664A true NZ262664A (en)	1997-04-24

Family

ID=21799049

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NZ262664A NZ262664A (en)	1993-02-22	1994-02-22	Heterocyclic substituted derivatives, and medicaments thereof

Country Status (15)

Country	Link
EP (1)	EP0684823A4 (sv)
JP (1)	JP3173792B2 (sv)
KR (1)	KR960700722A (sv)
CN (1)	CN1118139A (sv)
AU (1)	AU680240B2 (sv)
BG (1)	BG99863A (sv)
CA (1)	CA2155123A1 (sv)
CZ (1)	CZ210895A3 (sv)
FI (1)	FI953916A (sv)
HU (1)	HUT71796A (sv)
NO (1)	NO953270L (sv)
NZ (1)	NZ262664A (sv)
PL (1)	PL310386A1 (sv)
SK (1)	SK102495A3 (sv)
WO (1)	WO1994018981A1 (sv)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5849736A (en) *	1993-11-24	1998-12-15	The Dupont Merck Pharmaceutical Company	Isoxazoline and isoxazole fibrinogen receptor antagonists
US5494921A (en) *	1994-09-16	1996-02-27	Merck & Co., Inc.	Fibrinogen receptor antagonists
ZA963391B (en) *	1995-05-24	1997-10-29	Du Pont Merck Pharma	Isoxazoline fibrinogen receptor antagonists.
IL123164A (en) *	1995-08-30	2001-03-19	Searle & Co	Meta-guanidine urea thiourea or azacyclic amino benzoic acid derivatives and pharmaceutical compositions containing them
US6100423A (en) *	1995-08-30	2000-08-08	G. D. Searle & Co.	Amino benzenepropanoic acid compounds and derivatives thereof
CA2233204A1 (en)	1995-09-29	1997-04-03	Joseph A. Jakubowski	Spiro compounds as inhibitors of fibrinogen-dependent platelet aggregation
WO1997023480A1 (en) *	1995-12-22	1997-07-03	The Du Pont Merck Pharmaceutical Company	Novel integrin receptor antagonists
WO1997035579A1 (en) *	1996-03-27	1997-10-02	Merck & Co., Inc.	A method for inhibiting clot formation
NZ333904A (en) *	1996-07-25	2000-06-23	Biogen Inc	VLA-4 and IIb/IIIa cell adhesion inhibitors
US5900414A (en) *	1996-08-29	1999-05-04	Merck & Co., Inc.	Methods for administering integrin receptor antagonists
DE19653647A1 (de) *	1996-12-20	1998-06-25	Hoechst Ag	Vitronectin - Rezeptorantagonisten, deren Herstellung sowie deren Verwendung
EP1023295A4 (en) *	1997-02-06	2001-01-24	Merck & Co Inc	PRODUCTS BY FIBRINOGEN RECEPTOR ANTAGONISTS
AU6780398A (en) *	1997-03-28	1998-10-22	Du Pont Merck Pharmaceutical Company, The	Heterocyclic integrin inhibitor prodrugs
US6303625B1 (en)	1998-07-27	2001-10-16	Ortho-Mcneil Pharmaceutical, Inc.	Triazolopyridines for the treatment of thrombosis disorders
CZ2002323A3 (cs) *	1999-07-28	2002-05-15	Aventis Pharmaceuticals Products Inc.	Substituované oxoazaheterocyklylové sloučeniny a farmaceutické prostředky, které je obsahují
EP1572693A1 (en) *	2002-12-20	2005-09-14	Pharmacia Corporation	Mitogen activated protein kinase-activated protein kinase-2 inhibiting compounds
US20100035756A1 (en) *	2006-07-12	2010-02-11	Syngenta Limited	Triazolophyridine derivatives as herbicides
JP2011516498A (ja) *	2008-04-04	2011-05-26	ギリアードサイエンシーズ，インコーポレイテッド	ステアロイル−ＣｏＡデサチュラーゼの阻害剤として使用するためのトリアゾロピリジノン誘導体
WO2010096722A1 (en) *	2009-02-20	2010-08-26	Takeda Pharmaceutical Company Limited	3-oxo-2, 3-dihydro- [1,2, 4] triazolo [4, 3-a]pyridines as soluble epoxide hydrolase (seh) inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5084466A (en) *	1989-01-31	1992-01-28	Hoffmann-La Roche Inc.	Novel carboxamide pyridine compounds which have useful pharmaceutical utility
GB8913011D0 (en) *	1989-06-06	1989-07-26	Wellcome Found	Anticonvulsant pyrazines
US5166154A (en) *	1989-10-17	1992-11-24	Boehringer Ingelheim Pharmaceuticals, Inc.	Imidazo[1,2-a]piperazines
US5278161A (en) *	1990-06-28	1994-01-11	Hoffmann-La Roche Inc.	Amino acid derivatives useful as renin inhibitors

1994
- 1994-02-22 JP JP51922094A patent/JP3173792B2/ja not_active Expired - Fee Related
- 1994-02-22 EP EP94909745A patent/EP0684823A4/en not_active Withdrawn
- 1994-02-22 SK SK1024-95A patent/SK102495A3/sk unknown
- 1994-02-22 CN CN94191248A patent/CN1118139A/zh active Pending
- 1994-02-22 WO PCT/US1994/001881 patent/WO1994018981A1/en not_active Application Discontinuation
- 1994-02-22 AU AU62465/94A patent/AU680240B2/en not_active Ceased
- 1994-02-22 NZ NZ262664A patent/NZ262664A/en unknown
- 1994-02-22 PL PL94310386A patent/PL310386A1/xx unknown
- 1994-02-22 CZ CZ952108A patent/CZ210895A3/cs unknown
- 1994-02-22 HU HU9502028A patent/HUT71796A/hu unknown
- 1994-02-22 CA CA002155123A patent/CA2155123A1/en not_active Abandoned
1995
- 1995-08-15 BG BG99863A patent/BG99863A/xx unknown
- 1995-08-21 NO NO953270A patent/NO953270L/no unknown
- 1995-08-21 FI FI953916A patent/FI953916A/sv not_active Application Discontinuation
- 1995-08-21 KR KR1019950703563A patent/KR960700722A/ko not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU6246594A (en)	1994-09-14
HUT71796A (en)	1996-02-28
CZ210895A3 (en)	1996-02-14
AU680240B2 (en)	1997-07-24
FI953916A0 (sv)	1995-08-21
NO953270L (no)	1995-10-19
WO1994018981A1 (en)	1994-09-01
JPH08507072A (ja)	1996-07-30
NO953270D0 (no)	1995-08-21
KR960700722A (ko)	1996-02-24
CA2155123A1 (en)	1994-09-01
SK102495A3 (en)	1997-01-08
BG99863A (en)	1996-02-29
EP0684823A1 (en)	1995-12-06
EP0684823A4 (en)	1997-07-09
HU9502028D0 (en)	1995-09-28
CN1118139A (zh)	1996-03-06
JP3173792B2 (ja)	2001-06-04
PL310386A1 (en)	1995-12-11
FI953916A (sv)	1995-08-21

Publication	Publication Date	Title
NZ262664A (en)	1997-04-24	Heterocyclic substituted derivatives, and medicaments thereof
AU647618B2 (en)	1994-03-24	Fibrinogen receptor antagonists
AU713676B2 (en)	1999-12-09	Integrin receptor antagonists
AU712082B2 (en)	1999-10-28	Fibrinogen receptor antagonists
EP0866705A1 (en)	1998-09-30	Fibrinogen receptor antagonists
EP0698023A1 (en)	1996-02-28	Fibrinogen receptor antagonists
EP0714295B1 (en)	2000-12-20	Fibrinogen receptor antagonists
US5340798A (en)	1994-08-23	Fibrinogen receptor antagonists
US5821241A (en)	1998-10-13	Fibrinogen receptor antagonists
AU709631B2 (en)	1999-09-02	Fibrinogen receptor antagonist prodrugs
GB2292147A (en)	1996-02-14	Piperidine derivative fibrinogen receptor antagonists
US5952306A (en)	1999-09-14	Integrin receptor antagonists
AU742197B2 (en)	2001-12-20	Fibrinogen receptor antagonists
GB2292558A (en)	1996-02-28	Fibrinogen receptor antagonists
US5789421A (en)	1998-08-04	Fibrinogen receptor antagonist
AU702025B2 (en)	1999-02-11	Fibrinogen receptor antagonist
US5889023A (en)	1999-03-30	Fibrinogen receptor antagonist
EP0781133A1 (en)	1997-07-02	Fibrinogen receptor antagonists
GB2312895A (en)	1997-11-12	Fibrinogen receptor antagonists
EP0957908A1 (en)	1999-11-24	Fibrinogen receptor antagonists