[go: up one dir, main page]

NO990362L - Nye stammer av Echerichia coli, metoder for fremstilling og bruk av disse i fermenteringsprosesser for produksjon av L-treonin - Google Patents

Nye stammer av Echerichia coli, metoder for fremstilling og bruk av disse i fermenteringsprosesser for produksjon av L-treonin

Info

Publication number
NO990362L
NO990362L NO990362A NO990362A NO990362L NO 990362 L NO990362 L NO 990362L NO 990362 A NO990362 A NO 990362A NO 990362 A NO990362 A NO 990362A NO 990362 L NO990362 L NO 990362L
Authority
NO
Norway
Prior art keywords
production
threonine
methods
fermentation processes
making
Prior art date
Application number
NO990362A
Other languages
English (en)
Other versions
NO320044B1 (no
NO990362D0 (no
Inventor
Ming-Der Wang
Jill S Bradshaw
Stacia L Swisher
Hungming James Liaw
Paul D Hanke
Thomas P Binder
Original Assignee
Archer Daniels Midland Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Archer Daniels Midland Co filed Critical Archer Daniels Midland Co
Publication of NO990362D0 publication Critical patent/NO990362D0/no
Publication of NO990362L publication Critical patent/NO990362L/no
Publication of NO320044B1 publication Critical patent/NO320044B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01003—Homoserine dehydrogenase (1.1.1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/01039—Homoserine kinase (2.7.1.39)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/02—Phosphotransferases with a carboxy group as acceptor (2.7.2)
    • C12Y207/02004—Aspartate kinase (2.7.2.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03001—Threonine synthase (4.2.3.1)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO19990362A 1996-07-30 1999-01-26 Nye stammer av Echerichia coli, metoder for fremstilling og bruk av disse i fermenteringsprosesser for produksjon av L-treonin NO320044B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2240796P 1996-07-30 1996-07-30
PCT/US1997/013359 WO1998004715A1 (en) 1996-07-30 1997-07-30 Novel strains of escherichia coli, methods of preparing the same and use thereof in fermentation processes for l-threonine production

Publications (3)

Publication Number Publication Date
NO990362D0 NO990362D0 (no) 1999-01-26
NO990362L true NO990362L (no) 1999-01-26
NO320044B1 NO320044B1 (no) 2005-10-17

Family

ID=21809430

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19990362A NO320044B1 (no) 1996-07-30 1999-01-26 Nye stammer av Echerichia coli, metoder for fremstilling og bruk av disse i fermenteringsprosesser for produksjon av L-treonin

Country Status (20)

Country Link
US (1) US5939307A (no)
EP (1) EP0917578B1 (no)
JP (2) JP4919529B2 (no)
KR (1) KR20000029691A (no)
CN (1) CN1261576C (no)
AT (1) ATE421587T1 (no)
AU (1) AU730102B2 (no)
BR (1) BR9710503A (no)
CA (1) CA2262813C (no)
DE (1) DE69739234D1 (no)
HU (1) HUP9903856A2 (no)
ID (1) ID19402A (no)
IL (3) IL128293A (no)
NO (1) NO320044B1 (no)
NZ (1) NZ334032A (no)
PL (1) PL191395B1 (no)
RU (1) RU2212448C2 (no)
TR (1) TR199900213T2 (no)
WO (1) WO1998004715A1 (no)
ZA (1) ZA976803B (no)

Families Citing this family (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE290602T1 (de) * 1997-10-04 2005-03-15 Degussa Verfahren zur mikrobiellen herstellung von aminosäuren der aspartat- und/oder glutamatfamilie und im verfahren einsetzbare mittel
PE20010049A1 (es) * 1999-04-09 2001-02-26 Ajinomoto Kk Bacteria que produce l-aminoacido y metodo para producir el l-aminoacido
US6984512B1 (en) * 1999-08-02 2006-01-10 Archer-Daniels-Midland Company Bacterial strains, methods of preparing the same and use thereof in fermentation processes for L-lysine production
CA2400777A1 (en) * 2000-05-27 2001-12-06 Degussa Ag Process for the fermentative preparation of l-threonine
AU2001265969A1 (en) * 2000-07-18 2002-01-30 Degussa A.G. Process for the fermentative preparation of l-threonine
AU2002220542A1 (en) * 2000-08-31 2002-03-13 Degussa A.G. Fermentation process for the preparation of l-threonine
US6562601B2 (en) * 2000-08-31 2003-05-13 Degussa Ag Fermentation process for the preparation of L-threonine
US20030190712A1 (en) * 2000-08-31 2003-10-09 Degussa Ag Fermentation process for the preparation of L-threonine
US7220571B2 (en) 2000-09-28 2007-05-22 Archer-Daniels-Midland Company Escherichia coli strains which over-produce L-threonine and processes for the production of L-threonine by fermentation
KR100427480B1 (ko) * 2001-01-16 2004-04-27 씨제이 주식회사 Ｌ-쓰레오닌의 제조방법
US7368266B2 (en) * 2001-02-13 2008-05-06 Cj Corporation Method for L-threonine production
KR100397423B1 (ko) * 2001-02-13 2003-09-13 씨제이 주식회사 Ｌ-쓰레오닌의 제조방법
WO2002081631A2 (en) 2001-04-04 2002-10-17 Genencor International, Inc. Uncoupled productive and catabolic host cell pathways
AU2002314738A1 (en) * 2001-04-04 2002-10-21 Genencor International, Inc. Methods for the production of products in host cells
KR100426808B1 (ko) * 2001-06-19 2004-04-13 씨제이 주식회사 엘-쓰레오닌 생산 미생물 및 이를 이용한 엘-쓰레오닌 제조방법
KR100426807B1 (ko) * 2001-06-19 2004-04-13 씨제이 주식회사 엘-쓰레오닌 생산 미생물 및 이를 이용한 엘-쓰레오닌 제조방법
ATE415478T1 (de) * 2001-07-06 2008-12-15 Evonik Degussa Gmbh Fermentationsverfahren zur herstellung von l- aminosäuren unter verwendung von stämmen aus der familie der enterobacteriaceae
DE10132945A1 (de) * 2001-07-06 2003-01-16 Degussa Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
EP1686184B1 (en) * 2001-07-11 2008-08-27 Evonik Degussa GmbH Process for the preparation of L-threonine using strains of the enterobacteriaceae family
DE60213414T2 (de) * 2001-07-11 2007-09-27 Degussa Gmbh Verfahren zur herstellung von l-threonin unter verwendung von stämmen der familie enterobacteriaceae
AU2002354853A1 (en) * 2001-07-18 2003-03-03 Degussa Ag Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
KR100547882B1 (ko) 2002-02-26 2006-02-01 삼성전자주식회사 안테나 선택 다이버시티를 지원하는 이동통신시스템에서순방향 채널 상태 정보를 송수신하는 방법 및 장치
RU2244007C2 (ru) * 2002-02-27 2005-01-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Способ получения l-треонина, штамм escherichia coli - продуцент треонина (варианты)
DE10210960A1 (de) 2002-03-13 2003-09-25 Degussa Verfahren zur fermentativen Hestellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
KR100451299B1 (ko) * 2002-03-21 2004-10-06 씨제이 주식회사 Ｌ―쓰레오닌의 제조방법
US7378267B1 (en) 2002-05-16 2008-05-27 Cheil Jedang Corporation Method for L-threonine production
CA2500741C (en) * 2002-10-04 2017-02-28 Genencor International, Inc. Glucose transport mutants for production of biomaterial
KR100478468B1 (ko) * 2003-09-06 2005-03-23 씨제이 주식회사 Ｌ―쓰레오닌의 제조방법
JP4380305B2 (ja) * 2003-11-21 2009-12-09 味の素株式会社 発酵法によるｌ−アミノ酸の製造法
RU2275424C2 (ru) * 2003-12-05 2006-04-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) Способ получения l-треонина с использованием бактерий, принадлежащих к роду escherichia
RU2316588C1 (ru) * 2004-01-30 2008-02-10 Адзиномото Ко., Инк. Бактерия - продуцент l-аминокислоты и способ получения l-аминокислоты (варианты)
US20050181488A1 (en) * 2004-02-12 2005-08-18 Akhverdian Valery Z. Method for producing L-threonine using bacteria belonging to the genus Escherichia
RU2288264C2 (ru) * 2004-02-12 2006-11-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) Бактерия, принадлежащая к роду escherichia - продуцент l-треонина и способ получения l-треонина
US7915018B2 (en) 2004-10-22 2011-03-29 Ajinomoto Co., Inc. Method for producing L-amino acids using bacteria of the Enterobacteriaceae family
US20070212764A1 (en) * 2005-01-19 2007-09-13 Ptitsyn Leonid R Method for producing l-amino acids using bacterium of the enterobacteriaceae family
US7723097B2 (en) * 2005-03-11 2010-05-25 Archer-Daniels-Midland Company Escherichia coli strains that over-produce L-threonine and processes for their production
DE102005018835A1 (de) 2005-04-22 2006-11-02 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren unter Verwendung verbesserter Stämme der Familie Enterobacteriaceae
WO2007001982A1 (en) * 2005-06-20 2007-01-04 Archer-Daniels-Midland Company Altered glyoxylate shunt for improved production of aspartate-derived amino acids and chemicals
JP2009095237A (ja) * 2006-02-02 2009-05-07 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
JP2009118740A (ja) * 2006-03-03 2009-06-04 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
EP2055771A3 (en) 2006-03-23 2009-07-08 Ajinomoto Co., Inc. A method for producing an L-amino acid using bacterium of the Enterobacteriaceae family with attenuated expression of a gene coding for small RNA
JP2009165355A (ja) 2006-04-28 2009-07-30 Ajinomoto Co Inc Ｌ−アミノ酸を生産する微生物及びｌ−アミノ酸の製造法
EP2021458A1 (en) 2006-05-23 2009-02-11 Ajinomoto Co., Inc. A method for producing an l-amino acid using a bacterium of the enterobacteriaceae family
RU2006143864A (ru) 2006-12-12 2008-06-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА ENTEROBACTERIACEAE, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНОВ cynT, cynS, cynX, ИЛИ cynR, ИЛИ ИХ КОМБИНАЦИИ
JP2010041920A (ja) 2006-12-19 2010-02-25 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
EP2116595B1 (en) 2007-01-22 2017-04-05 Ajinomoto Co., Inc. An l-amino acid-producing microorganism and a method for producing an l-amino acid
JP2010110216A (ja) 2007-02-20 2010-05-20 Ajinomoto Co Inc Ｌ−アミノ酸または核酸の製造方法
JP2010110217A (ja) 2007-02-22 2010-05-20 Ajinomoto Co Inc Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造法
DE102007051024A1 (de) 2007-03-05 2008-09-11 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
KR100858913B1 (ko) * 2007-03-09 2008-09-17 한국과학기술원 부위특이적 변이에 의해 제조된 고수율의 ｌ－쓰레오닌생산균주 및 이를 이용한 ｌ－쓰레오닌의 제조방법
EP1975241A1 (de) 2007-03-29 2008-10-01 Evonik Degussa GmbH Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
EP2149608A4 (en) 2007-04-16 2013-02-20 Ajinomoto Kk PROCESS FOR PREPARING AN ORGANIC ACID
CN101939412B (zh) 2007-09-04 2016-01-20 味之素株式会社 生产氨基酸的微生物以及氨基酸的生产方法
DE102007044134A1 (de) 2007-09-15 2009-03-19 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
DE102007052270A1 (de) 2007-11-02 2009-05-07 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
EP2060636A1 (de) 2007-11-14 2009-05-20 Evonik Degussa GmbH Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
WO2009072562A1 (ja) 2007-12-06 2009-06-11 Ajinomoto Co., Inc. 有機酸の製造方法
KR20090075549A (ko) * 2008-01-04 2009-07-08 씨제이제일제당 (주) 향상된 ｌ-쓰레오닌 생산능을 갖는 대장균 및 이를 이용한ｌ-쓰레오닌의 생산 방법
KR100966324B1 (ko) 2008-01-08 2010-06-28 씨제이제일제당 (주) 향상된 ｌ－쓰레오닌 생산능을 갖는 대장균 및 이를 이용한ｌ－쓰레오닌의 생산 방법
JP2011067095A (ja) 2008-01-10 2011-04-07 Ajinomoto Co Inc 発酵法による目的物質の製造法
BRPI0906795A2 (pt) * 2008-01-23 2015-08-18 Ajinomoto Kk Método para produzir um l-aminoácido
RU2008105793A (ru) 2008-02-19 2009-08-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) Способ конструирования оперонов, содержащих трансляционно сопряженные гены, бактерия, содержащая такой оперон, способ продукции полезного метаболита и способ мониторинга экспрессии гена
EP2098597A1 (de) 2008-03-04 2009-09-09 Evonik Degussa GmbH Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
DE102008002309A1 (de) 2008-06-09 2009-12-10 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
DE102008040352A1 (de) 2008-07-11 2010-01-14 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Tryptophan unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
DE102008044768A1 (de) 2008-08-28 2010-03-04 Evonik Degussa Gmbh Verfahren zur Herstellung von organisch-chemischen Verbindungen unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
WO2010027022A1 (ja) 2008-09-05 2010-03-11 味の素株式会社 Ｌ－アミノ酸生産菌及びｌ－アミノ酸の製造法
BRPI0918299B1 (pt) 2008-09-08 2018-08-14 Ajinomoto Co., Inc. Método para produzir um l-aminoácido
JP2012029565A (ja) 2008-11-27 2012-02-16 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
BRPI1007069A2 (pt) 2009-01-23 2015-08-25 Ajinomoto Kk Método para produzir um l-aminoácido.
EP2267145A1 (de) 2009-06-24 2010-12-29 Evonik Degussa GmbH Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
WO2011013707A1 (ja) 2009-07-29 2011-02-03 味の素株式会社 Ｌ-アミノ酸の製造法
JP2012196144A (ja) 2009-08-03 2012-10-18 Ajinomoto Co Inc ビブリオ属細菌を用いたｌ−リジンの製造法
JP2012223092A (ja) 2009-08-28 2012-11-15 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
JP2013013329A (ja) 2009-11-06 2013-01-24 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
RU2460793C2 (ru) 2010-01-15 2012-09-10 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) Способ получения l-аминокислот с использованием бактерий семейства enterobacteriaceae
JP2013074795A (ja) 2010-02-08 2013-04-25 Ajinomoto Co Inc 変異型ｒｐｓＡ遺伝子及びＬ−アミノ酸の製造法
RU2471868C2 (ru) 2010-02-18 2013-01-10 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) Мутантная аденилатциклаза, днк, кодирующая ее, бактерия семейства enterobacteriaceae, содержащая указанную днк, и способ получения l-аминокислот
RU2501858C2 (ru) 2010-07-21 2013-12-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА Enterobacteriaceae
RU2482188C2 (ru) 2010-07-21 2013-05-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПОЛУЧЕНИЯ L-АРГИНИНА С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ РОДА Escherichia, В КОТОРОЙ ИНАКТИВИРОВАН ОПЕРОН astCADBE
JP2014036576A (ja) 2010-12-10 2014-02-27 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
EP2479279A1 (de) 2011-01-20 2012-07-25 Evonik Degussa GmbH Verfahren zur fermentativen Herstellung schwefelhaltiger Aminosäuren
CN102181502B (zh) * 2011-05-17 2014-03-19 内蒙古阜丰生物科技有限公司 一种提高发酵生产l-苏氨酸产率的方法
WO2012157699A1 (ja) 2011-05-18 2012-11-22 味の素株式会社 動物用免疫賦活剤、それを含む飼料及びその製造方法
RU2011134436A (ru) 2011-08-18 2013-10-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Способ получения l-аминокислоты с использованием бактерии семейства enterobacteriaceae, обладающей повышенной экспрессией генов каскада образования флагелл и клеточной подвижности
EP2628792A1 (de) 2012-02-17 2013-08-21 Evonik Industries AG Zelle mit verringerter ppGppase-Aktivität
AU2013260096A1 (en) * 2012-05-11 2014-11-27 Regents Of The University Of Minnesota Biosynthetic pathways, recombinant cells, and methods
ES2689754T3 (es) 2012-08-20 2018-11-15 Evonik Degussa Gmbh Procedimiento para la preparación fermentativa de L-aminoácidos utilizando cepas mejoradas de la familia Enterobacteriaceae
EP2762571A1 (de) 2013-01-30 2014-08-06 Evonik Industries AG Mikroorganismus und Verfahren zur fermentativen Herstellung von Aminosäuren
RU2013118637A (ru) 2013-04-23 2014-10-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА ENTEROBACTERIACEAE, В КОТОРОЙ РАЗРЕГУЛИРОВАН ГЕН yjjK
CN105008532B (zh) 2013-05-13 2017-07-21 味之素株式会社 L‑氨基酸的制造方法
RU2013140115A (ru) 2013-08-30 2015-03-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ НАРУШЕНА ЭКСПРЕССИЯ КЛАСТЕРА ГЕНОВ znuACB
JP2016192903A (ja) 2013-09-17 2016-11-17 味の素株式会社 海藻由来バイオマスからのｌ−アミノ酸の製造方法
JP5958653B2 (ja) 2013-10-02 2016-08-02 味の素株式会社 アンモニア制御装置およびアンモニア制御方法
RU2013144250A (ru) 2013-10-02 2015-04-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНА, КОДИРУЮЩЕГО ФОСФАТНЫЙ ТРАНСПОРТЕР
EP2886651B1 (en) 2013-10-21 2018-08-22 Ajinomoto Co., Inc. Method for producing l-amino acid
BR112016008830B1 (pt) 2013-10-23 2023-02-23 Ajinomoto Co., Inc Método para produzir uma substância alvo
RU2014105547A (ru) 2014-02-14 2015-08-20 Адзиномото Ко., Инк. СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА ENTEROBACTERIACEAE, ИМЕЮЩЕЙ СВЕРХЭКСПРЕССИРУЕМЫЙ ГЕН yajL
RU2015120052A (ru) 2015-05-28 2016-12-20 Аджиномото Ко., Инк. Способ получения L-аминокислоты с использованием бактерии семейства Enterobacteriaceae, в которой ослаблена экспрессия гена gshA
EP3420096A1 (en) 2016-02-25 2019-01-02 Ajinomoto Co., Inc. A method for producing l-amino acids using a bacterium of the family enterobacteriaceae overexpressing a gene encoding an iron exporter
WO2017151059A1 (en) * 2016-02-29 2017-09-08 Agency For Science, Technology And Research Multiplexable activation of silent biosynthetic clusters in native actinomycete hosts for natural product discovery
JP7066977B2 (ja) 2017-04-03 2022-05-16 味の素株式会社 Ｌ－アミノ酸の製造法
US11053526B2 (en) 2018-08-09 2021-07-06 Evonik Operations Gmbh Process for preparing L amino acids using improved strains of the enterobacteriaceae family
EP3608409A1 (en) 2018-08-09 2020-02-12 Evonik Operations GmbH Process for preparing l amino acids using improved strains of the enterobacteriaceae family
RU2697219C1 (ru) * 2018-09-28 2019-08-13 Федеральное государственное бюджетное учреждение "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Национального исследовательского центра "Курчатовский институт" (НИЦ "Курчатовский институт" - ГосНИИгенетика) Рекомбинантный штамм бактерии Escherichia coli - продуцент L-треонина
EP3861109A1 (en) 2018-10-05 2021-08-11 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
CN109554322B (zh) * 2018-12-03 2020-08-04 江南大学 一种高产l-苏氨酸的重组大肠杆菌及其构建方法
BR112021014194A2 (pt) 2019-02-22 2021-12-28 Ajinomoto Kk Método para a produção de um l-aminoácido
WO2020204179A1 (en) 2019-04-05 2020-10-08 Ajinomoto Co., Inc. Method of producing l-amino acids
WO2021060438A1 (en) 2019-09-25 2021-04-01 Ajinomoto Co., Inc. Method for producing l-amino acids by bacterial fermentation
EP4034668B1 (en) 2019-09-25 2024-04-17 Ajinomoto Co., Inc. Method for producing 2-methyl-butyric acid by bacterial fermentation
RU2748676C1 (ru) * 2020-10-05 2021-05-28 Федеральное государственное бюджетное учреждение "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Национального исследовательского центра "Курчатовский институт" (НИЦ "Курчатовский институт" - ГосНИИгенетика) Штамм Escherichia coli с инактивированным геном ydgI - продуцент L-треонина
AU2022258873A1 (en) 2021-04-16 2023-11-30 Inbiose N.V. Fermentative production
WO2022219188A1 (en) 2021-04-16 2022-10-20 Inbiose N.V. Cellular production of sialylated di- and/or oligosaccharides
IL316086A (en) 2022-04-04 2024-12-01 Ajinomoto Kk Method for controlling parasitic plants

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1097908A (en) * 1964-07-01 1968-01-03 Chugai Pharmaceutical Co Ltd A fermentation process for the production of l-threonine
GB1122508A (en) * 1965-07-16 1968-08-07 Kyowa Hakko Kogyo Kk Process for producing l-threonine
GB1176125A (en) * 1967-01-21 1970-01-01 Kyowa Hakko Kogyo Kk Process for Producing L-Threonine.
US3582471A (en) * 1967-07-03 1971-06-01 Ajinomoto Kk Method of producing threonine by fermentation
US3580810A (en) * 1967-07-28 1971-05-25 Ajinomoto Kk Fermentative production of l-threonine
GB1185130A (en) * 1967-09-12 1970-03-18 Kyowa Hakko Kogyo Kk Process for producing L-Threonine
US3684654A (en) * 1968-06-17 1972-08-15 Kyowa Hakko Kogyo Kk Process for producing l-threonine
JPS4825515B1 (no) * 1968-08-17 1973-07-30
GB1342308A (en) * 1970-01-22 1974-01-03 Kyowa Hakko Kogyo Kk Production of threonine and lysine by fermentation
JPS53101591A (en) * 1977-02-15 1978-09-05 Ajinomoto Co Inc Preparation of l-threonine by fermentation
SU943282A1 (ru) * 1979-07-13 1982-07-15 Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Способ получени L-треонина
JPS55131397A (en) * 1979-04-02 1980-10-13 Ajinomoto Co Inc Preparation of l-threonine by fermentation
JPS55156591A (en) * 1979-05-23 1980-12-05 Ajinomoto Co Inc Method for stabilizing property of bacteria containing plasmid
JPS56134993A (en) * 1980-03-21 1981-10-22 Tanabe Seiyaku Co Ltd Preparation of l-threonine by fermentation method
JPS57186496A (en) * 1981-05-11 1982-11-16 Ajinomoto Co Inc Preparation of l-threonine by fermentation
US5236831A (en) * 1981-12-29 1993-08-17 Kiowa Hakko Kogyo Co., Ltd. Amino acid synthesis in corynebacteria using E. coli genes
US4601983A (en) * 1983-06-15 1986-07-22 Ajinomoto Co., Inc. Coryneform bacteria carrying recombinant plasmids and their use in the fermentative production of L-threonine and L-isoleucine
JPH0783714B2 (ja) * 1983-08-29 1995-09-13 味の素株式会社 発酵法によるｌ―アミノ酸の製造法
JPS6062982A (ja) * 1983-09-14 1985-04-11 Ajinomoto Co Inc 組換えｄνａ，該組換えｄνａを有する細菌及び該細菌を用いるｌ−スレオニン又はｌ−イソロイシンの製造法
JPH0746994B2 (ja) * 1984-10-04 1995-05-24 味の素株式会社 発酵法によるｌ−アミノ酸の製造法
EP0205849B1 (en) * 1985-05-13 1991-12-04 Toray Industries, Inc. Process for producing l-threonine by fermentation
US5264353A (en) * 1985-08-23 1993-11-23 Toray Industries, Inc. Process for producing L-threonine by fermentation
US5342766A (en) * 1985-08-26 1994-08-30 Toray Industries, Inc. Process for producing L-threonine by fermentation with P. rettgeri.
EP0219808B1 (en) * 1985-10-18 1993-12-22 Toray Industries, Inc. Plasmid with wide host range
US5017483A (en) * 1986-02-20 1991-05-21 Kyowa Hakko Kogyo Co., Ltd. Process for producing L-threonine
JP2516625B2 (ja) * 1986-06-02 1996-07-24 三菱化学株式会社 Ｌ−スレオニンの製造法
US5188949A (en) * 1986-09-29 1993-02-23 Ajinomoto Co., Inc. Method for producing L-threonine by fermentation
US5164307A (en) * 1987-01-23 1992-11-17 Ajinomoto Co., Inc. Process for producing L-amino acids by fermentation
JPS6437295A (en) * 1987-07-31 1989-02-07 Kyowa Hakko Kogyo Kk Production of l-threonine by fermentation
EP0312089B1 (en) * 1987-10-15 1994-03-02 Mitsubishi Petrochemical Co., Ltd. Method for producing L-threonine
JP2600750B2 (ja) * 1988-01-21 1997-04-16 味の素株式会社 発酵法によるｌ―スレオニンの製造法
US5705371A (en) * 1990-06-12 1998-01-06 Ajinomoto Co., Inc. Bacterial strain of escherichia coli BKIIM B-3996 as the producer of L-threonine
WO1990004636A1 (en) * 1988-10-25 1990-05-03 Vsesojuzny Nauchno-Issledovatelsky Institut Genetiki I Selektsii Promyshlennykh Mikroorganizmov (Vniigenetika) Strain of bacteria escherichia coli, producer of l-threonine
JP2578492B2 (ja) * 1988-11-10 1997-02-05 協和醗酵工業株式会社 発酵法によるｌ−スレオニンの製造法
JP3046332B2 (ja) * 1990-08-02 2000-05-29 協和醗酵工業株式会社 発酵法によるアミノ酸の製造法
JP3006926B2 (ja) * 1991-09-04 2000-02-07 協和醗酵工業株式会社 発酵法によるｌ−スレオニンの製造法
JP3151073B2 (ja) * 1992-02-25 2001-04-03 協和醗酵工業株式会社 発酵法によるアミノ酸の製造法
TW258753B (en) * 1992-06-30 1995-10-01 Dev Center Biotechnology Direct fermentation of L-tryptophan by a recombinant microbe
DE69219775T3 (de) * 1992-10-14 2004-08-05 Ajinomoto Co., Inc. Neuartiges L-threoninproduzierendes Mikrobakterium und eine Herstellungsmethode für L-Threonin
US5998178A (en) * 1994-05-30 1999-12-07 Ajinomoto Co., Ltd. L-isoleucine-producing bacterium and method for preparing L-isoleucine through fermentation

Also Published As

Publication number Publication date
IL166146A (en) 2006-12-31
IL166145A0 (en) 2006-01-15
ZA976803B (en) 1998-02-19
EP0917578B1 (en) 2009-01-21
JP2012070752A (ja) 2012-04-12
CA2262813A1 (en) 1998-02-05
IL128293A0 (en) 1999-11-30
NO320044B1 (no) 2005-10-17
TR199900213T2 (xx) 1999-04-21
NZ334032A (en) 2000-09-29
CN1226931A (zh) 1999-08-25
NO990362D0 (no) 1999-01-26
HUP9903856A2 (hu) 2000-03-28
ATE421587T1 (de) 2009-02-15
IL128293A (en) 2006-12-31
ID19402A (id) 1998-07-09
JP2000515763A (ja) 2000-11-28
BR9710503A (pt) 2000-01-11
AU730102B2 (en) 2001-02-22
CA2262813C (en) 2011-09-13
PL191395B1 (pl) 2006-05-31
RU2212448C2 (ru) 2003-09-20
US5939307A (en) 1999-08-17
IL166146A0 (en) 2006-01-15
EP0917578A1 (en) 1999-05-26
JP4919529B2 (ja) 2012-04-18
IL166145A (en) 2006-12-31
KR20000029691A (ko) 2000-05-25
DE69739234D1 (de) 2009-03-12
AU3899497A (en) 1998-02-20
WO1998004715A1 (en) 1998-02-05
PL331351A1 (en) 1999-07-05
CN1261576C (zh) 2006-06-28

Similar Documents

Publication Publication Date Title
NO990362L (no) Nye stammer av Echerichia coli, metoder for fremstilling og bruk av disse i fermenteringsprosesser for produksjon av L-treonin
ATE513045T1 (de) Stamm von escherichia coli überproduzierend l- threonine, und verfahren zur herstellung von l- threoninen durch fermentation
ATE312192T1 (de) Verfahren zur fermentativen herstellung von aminosäuren und aminosäure-derivaten der phosphoglycerat-familie
DE602004014158D1 (de) Verfahren zur herstellung von l-lysin oder l-threonin unter verwendung von escherichia-bakterien mit abgeschwächter malatenzymaktivität
DE60230040D1 (de) Fermentationsverfahren zur herstellung von l-aminosäuren unter verwendung von stämmen aus der familie der enterobacteriaceae
AU2002345084A1 (en) Process for the preparation of l-amino acids using strains of the enterobacteriaceae family which contain an enhanced succ or sucd gene
HUP9700851A2 (hu) Eljárás L-lizin előállítására
ATE293696T1 (de) Mutierte alpha-amylase enzyme mit erhöhter stabilität
ATE404685T1 (de) Verfahren zur herstellung von l-aminosäuren mit stämmen der familie enterobacteriaceae in den das frur-gen deletiert worden ist
DE69627150D1 (de) Verfahren zur herstellung von gegen e.coli bakterien der familie cs4-cfa/1 gerichteten antikörpern
IL137256A0 (en) Frozen food product
EP1469738A4 (en) AROMATIC CHEESE SUBSTANCE AND PROCESS FOR PRODUCING THE SAME
Lazzi et al. Growth promotion of Bifidobacterium species by poultry bone and meat trimming hydrolyzate
AU2003290053A1 (en) Process for the fermentative preparation of l-amino acids using strains of the enterobacteriaceae family which contain an attenuated yjgf orf sequence
HUP9903899A2 (hu) Eljárás L-aminosavak fermentációs előállítására
ATE549405T1 (de) Bakterienmutanten zur l-lysinherstellung
CA2559662A1 (en) Novel antibiotic alternatives
Janeček et al. The synthesis of β-galactosidase in Escherichia coli in the presence of 7-azatryptophan
WO2007046943A3 (en) Method of producing biotin
DE60327182D1 (de) Verfahren zur herstellung von l-aminosäuren unter verwendung von stämmen der familie enterobacteriaceae
KR930013087A (ko) 폐수 정화용 효소균 제제의 제조방법
WO2003087352A3 (en) Enolase polypeptides and structures
RU96107294A (ru) Способ обогащения растительного сырья микробным белком
WO2004042044A3 (en) Crystal structures of bacterial guanylate kinases
TH7959A (th) กรรมวิธีสำหรับการผลิตแอล-ธรีโอไนน์ ด้วยการหมัก

Legal Events

Date Code Title Description
MK1K Patent expired