NO985095D0 - Substituerte indazolderivater og deres anvendelse som inhibitorer fosfodiesterase (PDE) type IV og produksjon av tumornekrosefaktor (TNF) - Google Patents

Substituerte indazolderivater og deres anvendelse som inhibitorer fosfodiesterase (PDE) type IV og produksjon av tumornekrosefaktor (TNF)

Info

Publication number: NO985095D0
Authority: NO; Norway
Prior art keywords: pde; phosphodiesterase; tnf; inhibitors; production
Prior art date: 1996-05-03

Application number

NO985095A

Other languages

English (en)

Other versions

NO985095L (no

NO312959B1 (no

Inventor

Anthony Marfat

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-05-03

Filing date

1998-11-02

Publication date

1998-11-02

1998-11-02 Application filed by Pfizer filed Critical Pfizer

1998-11-02 Publication of NO985095D0 publication Critical patent/NO985095D0/no

1998-12-29 Publication of NO985095L publication Critical patent/NO985095L/no

2002-07-22 Publication of NO312959B1 publication Critical patent/NO312959B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Immunology (AREA)
Oncology (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Reproductive Health (AREA)
Transplantation (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Urology & Nephrology (AREA)
Tropical Medicine & Parasitology (AREA)
Diabetes (AREA)
Obesity (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO19985095A 1996-05-03 1998-11-02 Substituerte indazolderivater, anvendelse derav samt farmasöytisk preparat NO312959B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US1686196P	1996-05-03	1996-05-03
PCT/IB1997/000323 WO1997042174A1 (en)	1996-05-03	1997-04-01	Substituted indazole derivatives and their use as inhibitors phosphodiesterase (pde) type iv and the production of tumor necrosis factor (tnf)

Publications (3)

Publication Number	Publication Date
NO985095D0 true NO985095D0 (no)	1998-11-02
NO985095L NO985095L (no)	1998-12-29
NO312959B1 NO312959B1 (no)	2002-07-22

Family

ID=21779401

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19985095A NO312959B1 (no)	1996-05-03	1998-11-02	Substituerte indazolderivater, anvendelse derav samt farmasöytisk preparat

Country Status (42)

Country	Link
US (2)	US6211222B1 (no)
EP (1)	EP0912521B1 (no)
JP (1)	JP3148254B2 (no)
KR (1)	KR100339935B1 (no)
CN (2)	CN1112359C (no)
AP (4)	AP2001002304A0 (no)
AR (1)	AR006906A1 (no)
AT (1)	ATE292626T1 (no)
AU (1)	AU725576B2 (no)
BG (1)	BG64211B1 (no)
BR (1)	BR9709051A (no)
CA (2)	CA2389918A1 (no)
CO (1)	CO4650038A1 (no)
CZ (1)	CZ292825B6 (no)
DE (1)	DE69732966T2 (no)
DZ (1)	DZ2217A1 (no)
EA (1)	EA002272B1 (no)
ES (1)	ES2238079T3 (no)
GT (1)	GT199700043A (no)
HK (1)	HK1019443A1 (no)
HN (1)	HN1997000046A (no)
HR (1)	HRP970227B1 (no)
HU (1)	HUP9902459A3 (no)
ID (1)	ID16856A (no)
IL (2)	IL152083A0 (no)
IS (1)	IS4871A (no)
MA (1)	MA24158A1 (no)
MY (1)	MY132499A (no)
NO (1)	NO312959B1 (no)
NZ (1)	NZ332240A (no)
OA (1)	OA10904A (no)
PE (1)	PE64598A1 (no)
PL (1)	PL329836A1 (no)
SK (1)	SK148298A3 (no)
TN (1)	TNSN97070A1 (no)
TR (1)	TR199802202T2 (no)
TW (1)	TW449585B (no)
UA (1)	UA65536C2 (no)
UY (1)	UY24532A1 (no)
WO (1)	WO1997042174A1 (no)
YU (1)	YU16397A (no)
ZA (1)	ZA973804B (no)

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AP2001002304A0 (en) *	1996-05-03	2001-12-31	Pfizer	Substituted indazole derivatives and related compounds
US6005118A (en) *	1996-05-03	1999-12-21	Caron; Stephane	Methods of preparing 4-cyano-4 (substituted indazole) cyclohexane-carboxylic acids useful as PDE4 inhibitors
AU3102697A (en)	1996-06-19	1998-01-07	Rhone-Poulenc Rorer Limited	Substituted azabicylic compounds and their use as inhibitors of the production of tnf and cyclic amp phosphodiesterase
WO1998050367A1 (en) *	1997-05-08	1998-11-12	Pfizer Products Inc.	Processes and intermediates for preparing substituted indazole derivatives
IL126745A (en) *	1997-11-04	2003-09-17	Pfizer Prod Inc	Methods of preparing 4-cyano-4- (substituted indazole) cyclohexanecarboxylic acids useful as pde4 inhibitors
EA200000385A1 (ru) *	1997-11-04	2000-10-30	Пфайзер Продактс Инк.	Терапевтически активные соединения на основе индазольной биоизостерической замены катехина в ингибиторах фосфодиэстеразы типа vi (pde4)
BR9813926A (pt) *	1997-11-04	2000-09-19	Pfizer Prod Inc	Substituição de bioisóstero de catecol por indazol em compostos terapeuticamente ativos
IL132407A0 (en) *	1998-10-21	2001-03-19	Pfizer Prod Inc	Method for treating congestive heart failure
JP2000198734A (ja) *	1998-12-30	2000-07-18	Pfizer Inc	胃運動性減弱および関連疾患の治療のための運動性増強薬
US6362213B1 (en)	1999-12-23	2002-03-26	Icos Corporation	Cyclic AMP-specific phosphodiesterase inhibitors
WO2001047915A1 (en) *	1999-12-23	2001-07-05	Icos Corporation	Cyclic amp-specific phosphodiesterase inhibitors
US7211594B2 (en) *	2000-07-31	2007-05-01	Signal Pharmaceuticals, Llc	Indazole compounds and compositions thereof as JNK inhibitors and for the treatment of diseases associated therewith
US6897231B2 (en) *	2000-07-31	2005-05-24	Signal Pharmaceuticals, Inc.	Indazole derivatives as JNK inhibitors and compositions and methods related thereto
US6953774B2 (en)	2000-08-11	2005-10-11	Applied Research Systems Ars Holding N.V.	Methods of inducing ovulation
DK1908463T3 (da)	2001-12-14	2011-11-28	Merck Serono Sa	Fremgangsmåder til at inducere ægløsning ved anvendelse af en ikke polypeptid-CAMP-niveaumodulator
US20040034084A1 (en) *	2002-05-24	2004-02-19	Celgene Corporation	Methods for using JNK inhibitors for treating or preventing disease-related wasting
US7196082B2 (en) *	2002-11-08	2007-03-27	Merck & Co. Inc.	Ophthalmic compositions for treating ocular hypertension
US20050019366A1 (en) *	2002-12-31	2005-01-27	Zeldis Jerome B.	Drug-coated stents and methods of use therefor
DE10318610A1 (de)	2003-04-24	2004-11-11	Elbion Ag	7-Azaindole und deren Verwendung als Therapeutika
US7601847B2 (en)	2004-10-26	2009-10-13	Wyeth	Preparation and purification of 4-(indazol-3-yl)phenols
US20070004777A1 (en) *	2005-03-23	2007-01-04	Bhagwat Shripad S	Methods for treating or preventing acute myelogenous leukemia
EP2258359A3 (en)	2005-08-26	2011-04-06	Braincells, Inc.	Neurogenesis by muscarinic receptor modulation with sabcomelin
EP1928437A2 (en)	2005-08-26	2008-06-11	Braincells, Inc.	Neurogenesis by muscarinic receptor modulation
JP2009512711A (ja)	2005-10-21	2009-03-26	ブレインセルス，インコーポレイティド	Ｐｄｅ阻害による神経新生の調節
AU2006308889A1 (en)	2005-10-31	2007-05-10	Braincells, Inc.	GABA receptor mediated modulation of neurogenesis
US20100216734A1 (en)	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
CN101484180B (zh) *	2006-04-21	2014-01-08	森托科尔公司	Cxcl13拮抗剂及其用于治疗炎性疾病的用途
EP2021000A2 (en)	2006-05-09	2009-02-11	Braincells, Inc.	Neurogenesis by modulating angiotensin
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
WO2010099217A1 (en)	2009-02-25	2010-09-02	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations
US20150119399A1 (en)	2012-01-10	2015-04-30	President And Fellows Of Harvard College	Beta-cell replication promoting compounds and methods of their use
CA3081750A1 (en)	2017-11-06	2019-05-09	Rapt Therapeutics, Inc.	Anticancer agents

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JPS5654437A (en) *	1979-10-09	1981-05-14	Konishiroku Photo Ind Co Ltd	Direct positive image forming method
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US5440038A (en) *	1993-12-07	1995-08-08	Miles Inc.	Process for the purification of substituted 4-amino-1,2,4-triazine-5-ones
WO1996012720A1 (en) *	1994-10-20	1996-05-02	Pfizer Inc.	Bicyclic tetrahydro pyrazolopyridines and their use as medicaments
DE69516298T2 (de) *	1994-10-21	2000-12-28	Elisha Technologies Co. L.L.C., Moberly	Korrosionsverhinderndes puffer-system für metallprodukte
AP2001002304A0 (en) *	1996-05-03	2001-12-31	Pfizer	Substituted indazole derivatives and related compounds
WO1998050367A1 (en) *	1997-05-08	1998-11-12	Pfizer Products Inc.	Processes and intermediates for preparing substituted indazole derivatives

1996
- 1996-05-03 AP AP2001002304A patent/AP2001002304A0/xx unknown
- 1996-05-03 AP APAP/P/2001/002294A patent/AP1147A/en active
1997
- 1997-01-04 UA UA98105434A patent/UA65536C2/uk unknown
- 1997-04-01 AP APAP/P/2001/002304A patent/AP0102304A0/en unknown
- 1997-04-01 CN CN97194356A patent/CN1112359C/zh not_active Expired - Fee Related
- 1997-04-01 HU HU9902459A patent/HUP9902459A3/hu unknown
- 1997-04-01 CZ CZ19983492A patent/CZ292825B6/cs not_active IP Right Cessation
- 1997-04-01 KR KR1019980708867A patent/KR100339935B1/ko not_active IP Right Cessation
- 1997-04-01 NZ NZ332240A patent/NZ332240A/xx unknown
- 1997-04-01 CA CA002389918A patent/CA2389918A1/en not_active Abandoned
- 1997-04-01 PL PL97329836A patent/PL329836A1/xx unknown
- 1997-04-01 IL IL15208397A patent/IL152083A0/xx unknown
- 1997-04-01 AT AT97907247T patent/ATE292626T1/de not_active IP Right Cessation
- 1997-04-01 TR TR1998/02202T patent/TR199802202T2/xx unknown
- 1997-04-01 IL IL12654797A patent/IL126547A/xx not_active IP Right Cessation
- 1997-04-01 AU AU19373/97A patent/AU725576B2/en not_active Ceased
- 1997-04-01 ES ES97907247T patent/ES2238079T3/es not_active Expired - Lifetime
- 1997-04-01 CA CA002252982A patent/CA2252982C/en not_active Expired - Fee Related
- 1997-04-01 WO PCT/IB1997/000323 patent/WO1997042174A1/en active IP Right Grant
- 1997-04-01 BR BR9709051A patent/BR9709051A/pt active Search and Examination
- 1997-04-01 TW TW086104176A patent/TW449585B/zh active
- 1997-04-01 SK SK1482-98A patent/SK148298A3/sk unknown
- 1997-04-01 EP EP97907247A patent/EP0912521B1/en not_active Expired - Lifetime
- 1997-04-01 EA EA199800882A patent/EA002272B1/ru not_active IP Right Cessation
- 1997-04-01 DE DE69732966T patent/DE69732966T2/de not_active Expired - Fee Related
- 1997-04-01 JP JP53967097A patent/JP3148254B2/ja not_active Expired - Fee Related
- 1997-04-04 HN HN1997000046A patent/HN1997000046A/es unknown
- 1997-04-10 GT GT199700043A patent/GT199700043A/es unknown
- 1997-04-28 UY UY24532A patent/UY24532A1/es not_active IP Right Cessation
- 1997-04-29 AR ARP970101769A patent/AR006906A1/es not_active Application Discontinuation
- 1997-04-29 YU YU16397A patent/YU16397A/sh unknown
- 1997-04-30 AP APAP/P/1997/000975A patent/AP1146A/en active
- 1997-04-30 TN TNTNSN97070A patent/TNSN97070A1/fr unknown
- 1997-04-30 PE PE1997000330A patent/PE64598A1/es not_active Application Discontinuation
- 1997-04-30 MA MA24577A patent/MA24158A1/fr unknown
- 1997-04-30 DZ DZ970064A patent/DZ2217A1/fr active
- 1997-05-02 ZA ZA973804A patent/ZA973804B/xx unknown
- 1997-05-02 MY MYPI97001923A patent/MY132499A/en unknown
- 1997-05-02 ID IDP971466A patent/ID16856A/id unknown
- 1997-05-02 HR HR970227A patent/HRP970227B1/xx not_active IP Right Cessation
- 1997-05-05 CO CO97023872A patent/CO4650038A1/es unknown
- 1997-11-04 US US08/963,904 patent/US6211222B1/en not_active Expired - Fee Related
1998
- 1998-10-16 IS IS4871A patent/IS4871A/is unknown
- 1998-10-23 OA OA9800201A patent/OA10904A/en unknown
- 1998-11-02 NO NO19985095A patent/NO312959B1/no not_active IP Right Cessation
- 1998-11-23 BG BG102946A patent/BG64211B1/bg unknown
1999
- 1999-09-27 US US09/406,220 patent/US6127398A/en not_active Expired - Fee Related
- 1999-10-08 HK HK99104439A patent/HK1019443A1/xx not_active IP Right Cessation
2002
- 2002-11-08 CN CN02149950A patent/CN1422849A/zh active Pending

Also Published As

Publication number	Publication date
NO985095L (no)	1998-12-29
AU1937397A (en)	1997-11-26
BG102946A (en)	1999-11-30
YU16397A (sh)	1999-12-27
IS4871A (is)	1998-10-16
JPH11508284A (ja)	1999-07-21
PL329836A1 (en)	1999-04-12
IL152083A0 (en)	2003-05-29
ES2238079T3 (es)	2005-08-16
CA2252982C (en)	2002-10-08
NO312959B1 (no)	2002-07-22
AP9700975A0 (en)	1997-07-31
HUP9902459A3 (en)	2001-10-29
TW449585B (en)	2001-08-11
CN1217714A (zh)	1999-05-26
BG64211B1 (bg)	2004-05-31
OA10904A (en)	2001-10-11
US6211222B1 (en)	2001-04-03
GT199700043A (es)	1998-10-02
CO4650038A1 (es)	1998-09-03
JP3148254B2 (ja)	2001-03-19
EA002272B1 (ru)	2002-02-28
HRP970227B1 (en)	2002-06-30
DE69732966T2 (de)	2005-09-08
IL126547A0 (en)	1999-08-17
ID16856A (id)	1997-11-13
CA2389918A1 (en)	1997-11-13
AP2001002294A0 (en)	2001-12-31
MY132499A (en)	2007-10-31
KR100339935B1 (ko)	2002-07-18
AP2001002304A0 (en)	2001-12-31
AP0102304A0 (en)	1997-11-03
NZ332240A (en)	2000-07-28
DE69732966D1 (de)	2005-05-12
UY24532A1 (es)	2000-09-29
EP0912521B1 (en)	2005-04-06
US6127398A (en)	2000-10-03
HRP970227A2 (en)	2000-12-31
PE64598A1 (es)	1998-10-26
HN1997000046A (es)	1997-06-26
CZ349298A3 (cs)	1999-09-15
TR199802202T2 (xx)	1999-02-22
CA2252982A1 (en)	1997-11-13
EP0912521A1 (en)	1999-05-06
ZA973804B (en)	1998-11-02
ATE292626T1 (de)	2005-04-15
EA199800882A1 (ru)	1999-06-24
CN1112359C (zh)	2003-06-25
AP1146A (en)	2003-02-25
WO1997042174A1 (en)	1997-11-13
AP1147A (en)	2003-02-25
AU725576B2 (en)	2000-10-12
AR006906A1 (es)	1999-09-29
HUP9902459A2 (hu)	1999-11-29
UA65536C2 (en)	2004-04-15
TNSN97070A1 (fr)	2005-03-15
HK1019443A1 (en)	2000-02-11
CZ292825B6 (cs)	2003-12-17
KR20000010751A (ko)	2000-02-25
MA24158A1 (fr)	1997-12-31
BR9709051A (pt)	1999-08-03
IL126547A (en)	2003-03-12
SK148298A3 (en)	2000-02-14
CN1422849A (zh)	2003-06-11
DZ2217A1 (fr)	2002-12-03

Publication	Publication Date	Title
NO985095D0 (no)	1998-11-02	Substituerte indazolderivater og deres anvendelse som inhibitorer fosfodiesterase (PDE) type IV og produksjon av tumornekrosefaktor (TNF)
NO986103L (no)	1998-12-23	Substituerte indazol-derivater og deres anvendelse som fosfodiesterase (PDE)type IV - og tumornekrose-faktor (TNF)inhibitorer
NO991048D0 (no)	1999-03-03	Indazolderivater og deres anvendelse som inhibitorer av fosfodiesterase (PDE) type IV og fremstillingen av tumornekrosefaktor (TNF)
DK1475377T3 (da)	2006-10-23	Indol-derivater og deres anvendelse som inhibitorer for phosphodiesterase 4
DK1614683T3 (da)	2008-03-25	Indazolforbindelser og farmaceutiske sammensætninger til inhibering af proteinkinaser og fremgangsmåder til deres anvendelse
AU2002226911A1 (en)	2002-06-03	Indol derivative and their use as inhibitors of p38 kinase
AU2001288374A1 (en)	2002-03-22	Substituted oxindole derivatives as tyrosine kinase inhibitors
HUP0004512A3 (en)	2003-01-28	4-aminothiazole derivatives, their preparation and their use as inhibitors of cyclin-dependent kinases
NO941679D0 (no)	1994-05-06	Gallesyrederivater, fremgangsmåte for fremstilling og deres anvendelse
AU4436396A (en)	1996-08-14	Hydrosoluble 3-arylidene-2-oxindole derivatives as tyrosine kinase inhibitors
AU2002212226A1 (en)	2002-03-22	Use of indole derivatives for treating illnesses of the central nervous system
DK0950657T3 (da)	2004-11-22	Substituerede carbazoler, fremgangsmåde til deres fremstilling og deres anvendelse som sPLA2-inhibitorer
AU3885900A (en)	2000-10-09	Inhibitors of the egf-receptor tyrosine kinase and their use
PT934280E (pt)	2003-08-29	Derivados 2-cianoiminoimidazolo inibidores da pde iv
AU3094197A (en)	1998-01-14	Bicyclic 4-aralkylaminopyrimidine derivatives as tyrosine kinase inhibitors
DK0983249T3 (da)	2002-07-08	Fremgangsmåder og mellemprodukter til fremstilling af substituerede indazolderivater
NO934227D0 (no)	1993-11-23	Pyrrolderivater, fremgangsm}te for deres fremstilling og terapeutiske anvendelse
AU2876000A (en)	2000-08-29	Tyrosine kinase inhibitors and methods of using the same
AU4917000A (en)	2000-12-05	Oligohydroxyl substituted benzofuran-3-yl and pyridofuranylurea derivatives as phosphodiesterase iv inhibitors

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